Localized epigenetic changes induced by D H recombination restricts recombinase to DJ H junctions

Nature Immunology

Volumn 13, Issue 12, 2012, Pages 1205-1212

  Subrahmanyam, Ramesh ^a   Du, Hansen ^a   Ivanova, Irina ^a   Chakraborty, Tirtha ^a,d,e   Ji, Yanhong ^b,d   Zhang, Yu ^c   Alt, Frederick W ^c   Schatz, David G ^b   Sen, Ranjan ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d XI'AN JIAOTONG UNIVERSITY   (China)

^e MODERNA THERAPEUTICS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEASE; RECOMBINASE; SIGNAL PEPTIDE;

ARTICLE; CONTROLLED STUDY; DH RECOMBINATION; EPIGENETICS; GENE REARRANGEMENT; GENETIC ANALYSIS; GENETIC RECOMBINATION; IMMUNOGLOBULIN HEAVY CHAIN GENE; PRIORITY JOURNAL;

ANIMALS; B-LYMPHOCYTES; CELL LINE; CHROMATIN; EPIGENESIS, GENETIC; GENE REARRANGEMENT, B-LYMPHOCYTE, HEAVY CHAIN; GENES, IMMUNOGLOBULIN HEAVY CHAIN; HISTONES; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN JOINING REGION; IMMUNOGLOBULIN VARIABLE REGION; MICE; PRECURSOR CELLS, B-LYMPHOID; RECOMBINASES; RECOMBINATION, GENETIC;

EID: 84869500767     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2447     Document Type: Article

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