DUSP6 is a novel transcriptional target of p53 and regulates p53-mediated apoptosis by modulating expression levels of Bcl-2 family proteins

FEBS Letters

Volumn 586, Issue 23, 2012, Pages 4233-4240

  Piya, Sujan ^a   Kim, Ji Young ^a   Bae, Jeehyeon ^b   Seol, Dai Wu ^c   Moon, Ae Ran ^a   Kim, Tae Hyoung ^a  

^a Chosun University   (South Korea)

^b CHA University   (South Korea)

^c Chung Ang University   (South Korea)

Author keywords

Bcl 2 family protein; Cell death; DUSP6; ERK; p53

Indexed keywords

DUAL SPECIFICITY PHOSPHATASE 6; FLUOROURACIL; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN BAD; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P53; SHORT HAIRPIN RNA;

APOPTOSIS; ARTICLE; BINDING SITE; CELL STRESS; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DUSP6 GENE; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE OVEREXPRESSION; GENE TARGETING; GENOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN STABILITY; TRANSACTIVATION; TRANSCRIPTION REGULATION;

APOPTOSIS; DUAL SPECIFICITY PHOSPHATASE 6; FLUOROURACIL; HCT116 CELLS; HUMANS; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84869489646     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.10.031     Document Type: Article

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