Comparative NMR-based metabonomic investigation of the metabolic phenotype associated with tienilic acid and tienilic acid isomer

Chemical Research in Toxicology

Volumn 25, Issue 11, 2012, Pages 2412-2422

  Coen, Muireann ^a   Rademacher, Peter M ^b   Zou, Wei ^c   Scott, Michael ^d   Ganey, Patricia E ^e   Roth, Robert ^e   Nelson, Sidney D ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF WASHINGTON   (United States)

^c Michigan State University ^*  (United States)

^d MICHIGAN STATE UNIVERSITY   (United States)

^e MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; HYPOTAURINE; TIENILIC ACID;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOENERGY; CHEMICAL ANALYSIS; CLINICAL CHEMISTRY; CONTROLLED STUDY; DISEASE COURSE; DISEASE MARKER; ENZYME ACTIVITY; HISTOPATHOLOGY; HOMEOSTASIS; LIVER TOXICITY; MALE; METABOLOME; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PHENOTYPE; RAT; TOXIC HEPATITIS;

ANIMALS; CHEMISTRY, CLINICAL; ENDPOINT DETERMINATION; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MOLECULAR STRUCTURE; PHENOTYPE; RATS; RATS, SPRAGUE-DAWLEY; STEREOISOMERISM; TICRYNAFEN; TOXICITY TESTS;

RATTUS;

EID: 84869479631     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx3002803     Document Type: Article

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