Antigenic targets in tienilic acid hepatitis: Both cytochrome P450 2C11 and 2C11-tienilic acid adducts are transported to the plasma membrane of rat hepatocytes and recognized by human sera

Journal of Clinical Investigation

Volumn 98, Issue 6, 1996, Pages 1471-1480

  Robin, Marie Anne ^a   Maratrat, Michel ^b   Le Roy, Marie ^a   Le Breton, François Pierre ^a   Bonierbale, Eric ^c   Dansette, Patrick ^c   Ballet, François ^b   Mansuy, Daniel ^c   Pessayre, Dominique ^a  

^a BEAUJON HOSPITAL   (France)

^b SANOFI   (France)

^c CNRS   (France)

Author keywords

cell traffic; immunoallergic hepatitis; microtubules; neoantigen; vesicular transport

Indexed keywords

CYTOCHROME P450; TIENILIC ACID;

ANIMAL CELL; ANTIGEN RECOGNITION; ARTICLE; DRUG PROTEIN BINDING; HUMAN; IMMUNE RESPONSE; MICROTUBULE; NONHUMAN; PRIORITY JOURNAL; RAT; TOXIC HEPATITIS;

EID: 0029778819     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118936     Document Type: Article

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