-
1
-
-
0034526865
-
Proceedings of the ATS workshop on refractory asthma: Current understanding, recommendations, and unanswered questions
-
American Thoracic Society
-
American Thoracic Society. Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions. Am J Respir Crit Care Med 2000;162:2341-51.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 2341-2351
-
-
-
2
-
-
0032875377
-
Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics
-
Wenzel SE, Schwartz LB, Langmack EL, et al. Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med 1999;160:1001-8. (Pubitemid 29442043)
-
(1999)
American Journal of Respiratory and Critical Care Medicine
, vol.160
, Issue.3
, pp. 1001-1008
-
-
Wenzel, S.E.1
Schwartz, L.B.2
Langmack, E.L.3
Halliday, J.L.4
Trudeau, J.B.5
Gibbs, R.L.6
Chu, H.W.7
-
3
-
-
61849086181
-
Mepolizumab (anti-IL 5) and exacerbations of refractory eosinophilic asthma
-
Haldar PBC, Hargadon B, Gupat S, et al. Mepolizumab (anti-IL 5) and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009;360:973-84.
-
(2009)
N Engl J Med
, vol.360
, pp. 973-984
-
-
Haldar, P.B.C.1
Hargadon, B.2
Gupat, S.3
-
4
-
-
0346041503
-
Distinguishing severe asthma phenotypes: Role of age at onset and eosinophilic inflammation
-
DOI 10.1016/j.jaci.2003.10.041
-
Miranda C, Busacker A, Balzar S, et al. Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation. J Allergy Clin Immunol 2004;113:101-8. (Pubitemid 38096168)
-
(2004)
Journal of Allergy and Clinical Immunology
, vol.113
, Issue.1
, pp. 101-108
-
-
Miranda, C.1
Busacker, A.2
Balzar, S.3
Trudeau, J.4
Wenzel, S.E.5
-
5
-
-
0035447569
-
Factors associated with persistent airflow limitation in severe asthma
-
ten Brinke A, Zwinderman AH, Sterk PJ, et al. Factors associated with persistent airflow limitation in severe asthma. Am J Respir Crit Care Med 2001;164:744-8. (Pubitemid 32881907)
-
(2001)
American Journal of Respiratory and Critical Care Medicine
, vol.164
, Issue.5
, pp. 744-748
-
-
Ten, B.A.1
Zwinderman, A.H.2
Sterk, P.J.3
Rabe, K.F.4
Bel, E.H.5
-
7
-
-
0030776790
-
Relationship between il-4 and il-5 mrna expression and disease severity in atopic asthma
-
Humbert M, Corrigan CJ, Kimmitt P, et al. Relationship between IL-4 and IL-5 mRNA expression and disease severity in atopic asthma. Am J Respir Crit Care Med 1997;156:704-8. (Pubitemid 27396404)
-
(1997)
American Journal of Respiratory and Critical Care Medicine
, vol.156
, Issue.3 I
, pp. 704-708
-
-
Humbert, M.1
Corrigan, C.J.2
Kimmitt, P.3
Till, S.J.4
Kay, A.B.5
Durham, S.R.6
-
8
-
-
61849155730
-
Mepolizumab in prednisone-dependent asthma with sputum eosinophilia
-
Nair P, Pizzichini M, Kjarsgaard MIM, et al. Mepolizumab in prednisone-dependent asthma with sputum eosinophilia. N Engl J Med 2009;360:985-93.
-
(2009)
N Engl J Med
, vol.360
, pp. 985-993
-
-
Nair, P.1
Pizzichini, M.2
Kjarsgaard, M.I.M.3
-
9
-
-
81455155725
-
Reslizumab for poorly controlled, eosinophilic asthma: A randomized, placebo-controlled study
-
Castro M, Mathur S, Hargreave F, et al. Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study. Am J Respir Crit Care Med 2011;184:1125-32.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 1125-1132
-
-
Castro, M.1
Mathur, S.2
Hargreave, F.3
-
10
-
-
85047693849
-
Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics
-
DOI 10.1172/JCI200317974
-
Flood-Page P, Menzies-Gow A, Phipps S, et al. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J Clin Invest 2003;112:1029-36. (Pubitemid 38056318)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.7
, pp. 1029-1036
-
-
Flood-Page, P.1
Menzies-Gow, A.2
Phipps, S.3
Ying, S.4
Wangoo, A.5
Ludwig, M.S.6
Barnes, N.7
Robinson, D.8
Kay, A.B.9
-
11
-
-
0033571732
-
Differential regulation of epithelial-derived C-C chemokine expression by IL-4 and the glucocorticoid budesonide
-
Stellato C, Matsukura S, Fal A, et al. Differential regulation of epithelial-derived C-C chemokine expression by IL-4 and the glucocorticoid budesonide. J Immunol 1999;163:5624-32.
-
(1999)
J Immunol
, vol.163
, pp. 5624-5632
-
-
Stellato, C.1
Matsukura, S.2
Fal, A.3
-
12
-
-
0034976854
-
Interleukin-13 upregulates eotaxin expression in airway epithelial cells by a STAT6-dependent mechanism
-
Matsukura S, Stellato C, Georas SN, et al. Interleukin-13 upregulates eotaxin expression in airway epithelial cells by a STAT6-dependent mechanism. Am J Respir Cell Mol Biol 2001;24:755-61. (Pubitemid 32550599)
-
(2001)
American Journal of Respiratory Cell and Molecular Biology
, vol.24
, Issue.6
, pp. 755-761
-
-
Matsukura, S.1
Stellato, C.2
Georas, S.N.3
Casolaro, V.4
Plitt, J.R.5
Miura, K.6
Kurosawa, S.7
Schindler, U.8
Schleimer, R.P.9
-
13
-
-
0037326942
-
Chemokines in asthma: Cooperative interaction between chemokines and IL-13
-
quiz 243
-
Zimmermann N, Hershey GK, Foster PS, et al. Chemokines in asthma: cooperative interaction between chemokines and IL-13. J Allergy Clin Immunol 2003;111:227-42; quiz 243.
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 227-242
-
-
Zimmermann, N.1
Hershey, G.K.2
Foster, P.S.3
-
14
-
-
16244381378
-
Eotaxin-2 and eotaxin-3 expression is associated with persistent eosinophilic bronchial inflammation in patients with asthma after allergen challenge
-
DOI 10.1016/j.jaci.2004.11.045
-
Ravensberg AJ, Ricciardolo FL, van Schadewijk A, et al. Eotaxin-2 and eotaxin-3 expression is associated with persistent eosinophilic bronchial inflammation in patients with asthma after allergen challenge. J Allergy Clin Immunol 2005;115:779-85. (Pubitemid 40460853)
-
(2005)
Journal of Allergy and Clinical Immunology
, vol.115
, Issue.4
, pp. 779-785
-
-
Ravensberg, A.J.1
Ricciardolo, F.L.M.2
Van Schadewijk, A.3
Rabe, K.F.4
Sterk, P.J.5
Hiemstra, P.S.6
Mauad, T.7
-
15
-
-
9144240999
-
Concerted expression of eotaxin-1, eotaxin-2, and eotaxin-3 in human bronchial epithelial cells
-
DOI 10.1016/j.cellimm.2003.10.001
-
Komiya A, Nagase H, Yamada H, et al. Concerted expression of eotaxin-1, eotaxin-2, and eotaxin-3 in human bronchial epithelial cells. Cell Immunol 2003;225:91-100. (Pubitemid 38091553)
-
(2003)
Cellular Immunology
, vol.225
, Issue.2
, pp. 91-100
-
-
Komiya, A.1
Nagase, H.2
Yamada, H.3
Sekiya, T.4
Yamaguchi, M.5
Sano, Y.6
Hanai, N.7
Furuya, A.8
Ohta, K.9
Matsushima, K.10
Yoshie, O.11
Yamamoto, K.12
Hirai, K.13
-
16
-
-
0034948630
-
Eotaxin expression after segmental allergen challenge in subjects with atopic asthma
-
Lilly CM, Nakamura H, Belostotsky OI, et al. Eotaxin expression after segmental allergen challenge in subjects with atopic asthma. Am J Respir Crit Care Med 2001;163:1669-75. (Pubitemid 32578774)
-
(2001)
American Journal of Respiratory and Critical Care Medicine
, vol.163
, Issue.7
, pp. 1669-1675
-
-
Lilly, C.M.1
Nakamura, H.2
Belostotsky, O.I.3
Haley, K.J.4
Garcia-Zepeda, E.A.5
Luster, A.D.6
Israel, E.7
-
17
-
-
0034969165
-
Eotaxin-3 but not eotaxin gene expression is upregulated in asthmatics 24 hours after allergen challenge
-
Berkman N, Ohnona S, Chung FK, et al. Eotaxin-3 but not eotaxin gene expression is upregulated in asthmatics 24 hours after allergen challenge. Am J Respir Cell Mol Biol 2001;24:682-7. (Pubitemid 32550589)
-
(2001)
American Journal of Respiratory Cell and Molecular Biology
, vol.24
, Issue.6
, pp. 682-687
-
-
Berkman, N.1
Ohnona, S.2
Chung, F.K.3
Breuer, R.4
-
18
-
-
33845987340
-
Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program
-
DOI 10.1016/j.jaci.2006.11.639, PII S0091674906030302
-
Moore WC, Bleecker ER, Curran-Everett D, et al. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol 2007;119:405-13. (Pubitemid 46210080)
-
(2007)
Journal of Allergy and Clinical Immunology
, vol.119
, Issue.2
, pp. 405-413
-
-
Moore, W.C.1
Bleecker, E.R.2
Curran-Everett, D.3
Erzurum, S.C.4
Ameredes, B.T.5
Bacharier, L.6
Calhoun, W.J.7
Castro, M.8
Chung, K.F.9
Clark, M.P.10
Dweik, R.A.11
Fitzpatrick, A.M.12
Gaston, B.13
Hew, M.14
Hussain, I.15
Jarjour, N.N.16
Israel, E.17
Levy, B.D.18
Murphy, J.R.19
Peters, S.P.20
Teague, W.G.21
Meyers, D.A.22
Busse, W.W.23
Wenzel, S.E.24
more..
-
19
-
-
33646945087
-
H2 cytokine IL-13
-
DOI 10.1016/j.jaci.2006.01.049, PII S0091674906003101
-
Trudeau J, Hu H, Chibana K, et al. Selective downregulation of prostaglandin E2-related pathways by the Th2 cytokine IL-13. J Allergy Clin Immunol 2006;117:1446-54. (Pubitemid 43795756)
-
(2006)
Journal of Allergy and Clinical Immunology
, vol.117
, Issue.6
, pp. 1446-1454
-
-
Trudeau, J.1
Hu, H.2
Chibana, K.3
Chu, H.W.4
Westcott, J.Y.5
Wenzel, S.E.6
-
20
-
-
79960993627
-
Safety of investigative bronchoscopy in the Severe Asthma Research Program
-
Moore WC, Evans MD, Bleecker ER, et al. Safety of investigative bronchoscopy in the Severe Asthma Research Program. J Allergy Clin Immunol 2011;128:328-336.e3.
-
(2011)
J Allergy Clin Immunol
, vol.128
-
-
Moore, W.C.1
Evans, M.D.2
Bleecker, E.R.3
-
21
-
-
0027231657
-
Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects
-
Fahy JV, Liu J, Wong H, et al. Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis 1993;147:1126-31. (Pubitemid 23149867)
-
(1993)
American Review of Respiratory Disease
, vol.147
, Issue.5
, pp. 1126-1131
-
-
Fahy, J.V.1
Liu, J.2
Wong, H.3
Boushey, H.A.4
-
22
-
-
80052145134
-
15-Lipoxygenase 1 interacts with phosphatidylethanolamine-binding protein to regulate MAPK signaling in human airway epithelial cells
-
Zhao J, O'Donnell VB, Balzar S, et al. 15-Lipoxygenase 1 interacts with phosphatidylethanolamine-binding protein to regulate MAPK signaling in human airway epithelial cells. Proc Natl Acad Sci USA 2011;108:14246-51.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 14246-14251
-
-
Zhao, J.1
O'Donnell, V.B.2
Balzar, S.3
-
23
-
-
0003011470
-
Quantile regression with bootstrapped standard errors
-
Gould W. Quantile regression with bootstrapped standard errors. Stata Tech Bull 1993;2:19-21.
-
(1993)
Stata Tech Bull
, vol.2
, pp. 19-21
-
-
Gould, W.1
-
24
-
-
79551511756
-
Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program
-
Balzar S, Fajt ML, Comhair SA, et al. Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program. Am J Respir Crit Care Med 2011;183:299-309.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 299-309
-
-
Balzar, S.1
Fajt, M.L.2
Comhair, S.A.3
-
26
-
-
0030942468
-
Expression of eotaxin by human lung epithelial cells. Induction by cytokines and inhibition by glucocorticoids
-
Lilly CM, Nakamura H, Kesselman H, et al. Expression of eotaxin by human lung epithelial cells: induction by cytokines and inhibition by glucocorticoids. J Clin Invest 1997;99:1767-73. (Pubitemid 27163829)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.7
, pp. 1767-1773
-
-
Lilly, C.M.1
Nakamura, H.2
Kesselman, H.3
Nagler-Anderson, C.4
Asano, K.5
Garcia-Zepeda, E.A.6
Rothenberg, M.E.7
Drazen, J.M.8
Luster, A.D.9
-
27
-
-
0031445441
-
Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co-localization of eotaxin mRNA to bronchial epithelial and endothelial cells
-
DOI 10.1002/eji.1830271252
-
Ying S, Robinson DS, Meng Q, et al. Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co-localization of eotaxin mRNA to bronchial epithelial and endothelial cells. Eur J Immunol 1997;27:3507-16. (Pubitemid 28018050)
-
(1997)
European Journal of Immunology
, vol.27
, Issue.12
, pp. 3507-3516
-
-
Ying, S.1
Robinson, D.S.2
Meng, Q.3
Rottman, J.4
Kennedy, R.5
Ringler, D.J.6
Mackay, C.R.7
Daugherty, B.L.8
Springer, M.S.9
Durham, S.R.10
Williams, T.J.11
Kay, A.B.12
-
28
-
-
33748787128
-
Epithelial differentiation is a determinant in the production of eotaxin-2 and -3 by bronchial epithelial cells in response to IL-4 and IL-13
-
DOI 10.1016/j.molimm.2006.04.008, PII S0161589006001568
-
van Wetering S, Zuyderduyn S, Ninaber DK, et al. Epithelial differentiation is a determinant in the production of eotaxin-2 and -3 by bronchial epithelial cells in response to IL-4 and IL-13. Mol Immunol 2007;44:803-11. (Pubitemid 44415012)
-
(2007)
Molecular Immunology
, vol.44
, Issue.5
, pp. 803-811
-
-
Van Wetering, S.1
Zuyderduyn, S.2
Ninaber, D.K.3
Van Sterkenburg, M.A.J.A.4
Rabe, K.F.5
Hiemstra, P.S.6
-
29
-
-
33644847416
-
Mast cell β-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities
-
Pang L, Nie M, Corbett L, et al. Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities. J Immunol 2006;176:3788-95. (Pubitemid 43364027)
-
(2006)
Journal of Immunology
, vol.176
, Issue.6
, pp. 3788-3795
-
-
Pang, L.1
Nie, M.2
Corbett, L.3
Sutcliffe, A.4
Knox, A.J.5
-
30
-
-
0035985401
-
Regulation of human eotaxin-3/CCL26 expression: Modulation by cytokines and glucocorticoids
-
Banwell ME, Tolley NS, Williams TJ, et al. Regulation of human eotaxin-3/CCL26 expression: modulation by cytokines and glucocorticoids. Cytokine 2002;17:317-23.
-
(2002)
Cytokine
, vol.17
, pp. 317-323
-
-
Banwell, M.E.1
Tolley, N.S.2
Williams, T.J.3
-
31
-
-
33847765099
-
Eotaxin-2 in sputum cell culture to evaluate asthma inflammation
-
DOI 10.1183/09031936.00060205
-
Scheicher ME, Teixeira MM, Cunha FQ, et al. Eotaxin-2 in sputum cell culture to evaluate asthma inflammation. Eur Respir J 2007;29:489-95. (Pubitemid 46372095)
-
(2007)
European Respiratory Journal
, vol.29
, Issue.3
, pp. 489-495
-
-
Scheicher, M.E.1
Teixeira, M.M.2
Cunha, F.Q.3
Teixeira Jr., A.L.4
Filho, J.T.5
Vianna, E.O.6
Cunha, F.Q.7
-
32
-
-
17144362809
-
Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation
-
DOI 10.1074/jbc.M406037200
-
Pope SM, Fulkerson PC, Blanchard C, et al. Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation. J Biol Chem 2005;280:13952-61. (Pubitemid 40517296)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.14
, pp. 13952-13961
-
-
Pope, S.M.1
Fulkerson, P.C.2
Blanchard, C.3
Akei, H.S.4
Nikolaidis, N.M.5
Zimmermann, N.6
Molkentin, J.D.7
Rothenberg, M.E.8
-
33
-
-
0037083509
-
Eotaxin-2 generation is differentially regulated by lipopolysaccharide and IL-4 in monocytes and macrophages
-
Watanabe K, Jose PJ, Rankin SM. Eotaxin-2 generation is differentially regulated by lipopolysaccharide and IL-4 in monocytes and macrophages. J Immunol 2002;168:1911-18. (Pubitemid 34135793)
-
(2002)
Journal of Immunology
, vol.168
, Issue.4
, pp. 1911-1918
-
-
Watanabe, K.1
Jose, P.J.2
Rankin, S.M.3
|