Identification and evaluation of twin-arginine translocase inhibitors

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 12, 2012, Pages 6223-6234

  Vasil, Michael L ^a   Tomaras, Andrew P ^a,b   Pritchard, Arthur E ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; BACTERIAL PROTEIN; ENZYME INHIBITOR; MALEIMIDE DERIVATIVE; N PHENYLMALEIMIDE; PHOSPHOLIPASE C; TWIN ARGININE TRANSLOCASE INHIBITOR; TWIN ARGININE TRANSLOCASE TRANSPORTED HEMOLYTIC PHOSPHOLIPASE C; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; BURKHOLDERIA PSEUDOMALLEI; CONTROLLED STUDY; HIGH THROUGHPUT SCREENING; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA;

ARABINOSE; BURKHOLDERIA PSEUDOMALLEI; CLONING, MOLECULAR; COLORIMETRY; ENZYME INDUCTION; ENZYME INHIBITORS; HIGH-THROUGHPUT SCREENING ASSAYS; MALEIMIDES; MEMBRANE TRANSPORT PROTEINS; NITRILES; PHOSPHORYLCHOLINE; PLASMIDS; POLYMERASE CHAIN REACTION; PSEUDOMONAS AERUGINOSA; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONES; TYPE C PHOSPHOLIPASES;

EID: 84869232603     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01575-12     Document Type: Article

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