A complex extracellular sphingomyelinase of Pseudomonas aeruginosa inhibits angiogenesis by selective cytotoxicity to endothelial cells

PLoS Pathogens

Volumn 5, Issue 5, 2009, Pages

  Vasil, Michael L ^a   Stonehouse, Martin J ^a   Vasil, Adriana I ^a   Wadsworth, Sandra J ^b,e   Goldfine, Howard ^b   Bolcome III, Robert E ^c,d   Chan, Joanne ^c,d  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e TEMPLE UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; ENHANCED GREEN FLUORESCENT PROTEIN; GRGDS PROTEIN; PROTEIN; RGD PROTEIN; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG; ANGIOGENESIS INHIBITOR; PHOSPHOTRANSFERASE; SPHINGOMYELIN SYNTHASE, PSEUDOMONAS AERUGINOSA;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASSAY; BLOOD CELL; CALCIUM SIGNALING; CELL INVASION; CELL MIGRATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DIABETIC RETINOPATHY; EMBRYO; ENDOTHELIUM CELL; ENZYME ACTIVE SITE; ENZYME ACTIVITY; FEMALE; FERTILIZATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INJECTION; MOUSE; MUTANT; NONHUMAN; PROTEIN MOTIF; PSEUDOMONAS AERUGINOSA; SEPSIS; TUMOR VASCULARIZATION; VASCULARIZATION; VASCULITIS; WILD TYPE; WOUND HEALING; ZEBRA FISH; ANIMAL; CELL MOTION; CHEMISTRY; CHO CELL; CRICETULUS; DRUG EFFECT; ENZYMOLOGY; FIBROBLAST; HAMSTER; METABOLISM; PHYSIOLOGY; TRANSGENIC ANIMAL; UMBILICAL VEIN;

DANIO RERIO; PSEUDOMONAS AERUGINOSA;

ANGIOGENESIS INHIBITORS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CALCIUM SIGNALING; CELL MOVEMENT; CHO CELLS; CRICETINAE; CRICETULUS; ENDOTHELIAL CELLS; FIBROBLASTS; HUMANS; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; PSEUDOMONAS AERUGINOSA; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS); UMBILICAL VEINS; ZEBRAFISH;

EID: 67249164000     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000420     Document Type: Article

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