Discovery and characterization of inhibitors of Pseudomonas aeruginosa type III secretion

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 5, 2010, Pages 1988-1999

  Aiello, Daniel ^a   Williams, John D ^a   Majgier Baranowska, Helena ^a   Patel, Ishan ^a   Peet, Norton P ^a   Huang, Jin ^b   Lory, Stephen ^b   Bowlin, Terry L ^a   Moir, Donald T ^a  

^a MICROBIOTIX INC   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAMIDE DERIVATIVE; ANTIBIOTIC AGENT; AROMATIC COMPOUND; BACTERIAL PROTEIN; BETA LACTAMASE; ELASTASE; EXOS PROTEIN; EXOT PROTEIN; HYBRID PROTEIN; LUX PROTEIN; MBX 1641; MBX 1668; MBX 1684; MBX 1685; MBX 1686; PHENOXYACETAMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; ENANTIOMER; ENZYME RELEASE; FEMALE; GENE TRANSLOCATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NONHUMAN; OPERON; PHOTORHABDUS LUMINESCENS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN SECRETION; PSEUDOMONAS AERUGINOSA; REPORTER GENE; STRUCTURE ACTIVITY RELATION; SUPERNATANT; TYPE III SECRETION SYSTEM; YERSINIA PESTIS;

ACETAMIDES; ADP RIBOSE TRANSFERASES; ANIMALS; BETA-LACTAMASES; CHO CELLS; CRICETINAE; CRICETULUS; DRUG DESIGN; DRUG DISCOVERY; GTPASE-ACTIVATING PROTEINS; HELA CELLS; HUMANS; LUCIFERASES; MULTIPROTEIN COMPLEXES; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; SECRETORY PATHWAY; VIRULENCE; VIRULENCE FACTORS;

EID: 77951249812     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01598-09     Document Type: Article

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