Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways

Nature Medicine

Volumn 18, Issue 11, 2012, Pages 1665-1672

  Bhargava, Prerna ^a   Li, Changlin ^b   Stanya, Kristopher J ^a   Jacobi, David ^a,c   Dai, Lingling ^a,d   Liu, Sihao ^a   Gangl, Matthew R ^a   Harn, Donald A ^b   Lee, Chih Hao ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c UNIVERSITY HOSPITAL OF TOURS   (France)

^d CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; GLYCAN; INSULIN; INTERLEUKIN 10; INTERLEUKIN 4; LACTO N FUCOPENTOSE III; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; FATTY LIVER; GLUCOSE TOLERANCE; IMMUNOMODULATION; INFLAMMATION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPOGENESIS; LIVER PROTECTION; MACROPHAGE; MALE; METABOLIC REGULATION; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE; AMINO SUGARS; ANIMALS; DENDRITIC CELLS; DIABETES MELLITUS, EXPERIMENTAL; DIET, HIGH-FAT; FATTY LIVER; HEP G2 CELLS; HUMANS; INFLAMMATION; INSULIN RESISTANCE; INTERLEUKIN-10; LIVER; MACROPHAGES; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, OBESE; POLYSACCHARIDES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION;

MUS; VERMES;

EID: 84869227969     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2962     Document Type: Article

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