Gliomagenesis arising from Pten- and Ink4a/Arf-deficient neural progenitor cells is mediated by the p53-Fbxw7/Cdc4 pathway, which controls c-Myc

Cancer Research

Volumn 72, Issue 22, 2012, Pages 6065-6075

  Kim, Hong Sug ^a   Woolard, Kevin ^a   Lai, Chen ^a   Bauer, Peter O ^a   Maric, Dragan ^a   Song, Hua ^a   Li, Aiguo ^a   Kotliarova, Svetlana ^a   Zhang, Wei ^a   Fine, Howard A ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARF PROTEIN; CELL PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; FBXW7 PROTEIN; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARF GENE; ARTICLE; CANCER GRADING; CANCER SURVIVAL; CARCINOGENESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL RENEWAL; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; GENE DELETION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE LOCUS; GENE MUTATION; GENE OVEREXPRESSION; GENE REPRESSION; GENE SILENCING; GLIOMA; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INK4A GENE; MALE; MUTANT; MUTATIONAL ANALYSIS; NONHUMAN; ONCOGENE; ONCOGENE C MYC; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE GENE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SURVIVAL TIME;

ANIMALS; APOPTOSIS; BRAIN NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; F-BOX PROTEINS; FEMALE; GLIOBLASTOMA; MALE; MICE; MICE, KNOCKOUT; NEURAL STEM CELLS; PROTO-ONCOGENE PROTEINS C-MYC; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN-PROTEIN LIGASES;

EID: 84869221943     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-2594     Document Type: Article

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