-
1
-
-
0031458813
-
Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling
-
Ericson J, Rashbass P Schedl A, Brenner-Morton S, Kawakami A, et al. (1997) Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell 90: 169-180.
-
(1997)
Cell
, vol.90
, pp. 169-180
-
-
Ericson, J.1
Rashbass, P.2
Schedl, A.3
Brenner-Morton, S.4
Kawakami, A.5
-
2
-
-
0034640087
-
Homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube
-
Briscoe J, Pierani A, Jessell TM, Ericson JA, (2000) Homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell 101: 435-445.
-
(2000)
Cell
, vol.101
, pp. 435-445
-
-
Briscoe, J.1
Pierani, A.2
Jessell, T.M.3
Ericson, J.A.4
-
3
-
-
50649088457
-
Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network
-
Dessaud E, McMahon AP, Briscoe J, (2008) Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network. Development 135: 2489-2503.
-
(2008)
Development
, vol.135
, pp. 2489-2503
-
-
Dessaud, E.1
McMahon, A.P.2
Briscoe, J.3
-
4
-
-
14844300927
-
The floor plate: multiple cells, multiple signals
-
Placzek M, Briscoe J, (2005) The floor plate: multiple cells, multiple signals. Nat Rev Neurosci 6: 230-240.
-
(2005)
Nat Rev Neurosci
, vol.6
, pp. 230-240
-
-
Placzek, M.1
Briscoe, J.2
-
5
-
-
77953045687
-
Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube
-
Ribes V, Balaskas N, Sasai N, Cruz C, Dessaud E, et al. (2010) Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube. Genes Dev 24: 1186-1200.
-
(2010)
Genes Dev
, vol.24
, pp. 1186-1200
-
-
Ribes, V.1
Balaskas, N.2
Sasai, N.3
Cruz, C.4
Dessaud, E.5
-
6
-
-
80054022786
-
Gli Proteins in Development and Disease
-
Hui C-c, Angers S, (2011) Gli Proteins in Development and Disease. Annu Rev Cell Dev Biol 27: 513-527.
-
(2011)
Annu Rev Cell Dev Biol
, vol.27
, pp. 513-527
-
-
Hui, C.-c.1
Angers, S.2
-
7
-
-
0029777408
-
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
-
Chiang C, Litingtung Y, Lee E, Young KE, Corden JL, et al. (1996) Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383: 407-413.
-
(1996)
Nature
, vol.383
, pp. 407-413
-
-
Chiang, C.1
Litingtung, Y.2
Lee, E.3
Young, K.E.4
Corden, J.L.5
-
8
-
-
0037111827
-
A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord
-
Wijgerde M, McMahon JA, Rule M, McMahon AP, (2002) A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord. Genes Dev 16: 2849-2864.
-
(2002)
Genes Dev
, vol.16
, pp. 2849-2864
-
-
Wijgerde, M.1
McMahon, J.A.2
Rule, M.3
McMahon, A.P.4
-
9
-
-
0033808256
-
Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3
-
Litingtung Y, Chiang C, (2000) Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3. Nat Neurosci 3: 979-985.
-
(2000)
Nat Neurosci
, vol.3
, pp. 979-985
-
-
Litingtung, Y.1
Chiang, C.2
-
10
-
-
0031855859
-
Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice
-
Ding Q, Motoyama J, Gasca S, Mo R, Sasaki H, et al. (1998) Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development 125: 2533-2543.
-
(1998)
Development
, vol.125
, pp. 2533-2543
-
-
Ding, Q.1
Motoyama, J.2
Gasca, S.3
Mo, R.4
Sasaki, H.5
-
11
-
-
0034055649
-
Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation
-
Park HL, Bai C, Platt KA, Matise MP, Beeghly A, et al. (2000) Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. Development 127: 1593-1605.
-
(2000)
Development
, vol.127
, pp. 1593-1605
-
-
Park, H.L.1
Bai, C.2
Platt, K.A.3
Matise, M.P.4
Beeghly, A.5
-
12
-
-
0030866154
-
Altered neural cell fates and medulloblastoma in mouse Patched mutants
-
Goodrich LV, Milenković L, Higgins KM, Scott MP, (1997) Altered neural cell fates and medulloblastoma in mouse Patched mutants. Science 277: 1109-1113.
-
(1997)
Science
, vol.277
, pp. 1109-1113
-
-
Goodrich, L.V.1
Milenković, L.2
Higgins, K.M.3
Scott, M.P.4
-
13
-
-
0037706929
-
Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification
-
Motoyama J, Milenković L, Iwama M, Shikata Y, Scott MP, et al. (2003) Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification. Dev Biol 259: 150-161.
-
(2003)
Dev Biol
, vol.259
, pp. 150-161
-
-
Motoyama, J.1
Milenković, L.2
Iwama, M.3
Shikata, Y.4
Scott, M.P.5
-
14
-
-
14644401158
-
A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube
-
Stamataki D, Ulloa F, Tsoni SV, Mynett A, Briscoe J, (2005) A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube. Genes Dev 19: 626-641.
-
(2005)
Genes Dev
, vol.19
, pp. 626-641
-
-
Stamataki, D.1
Ulloa, F.2
Tsoni, S.V.3
Mynett, A.4
Briscoe, J.5
-
15
-
-
84856094426
-
Gene regulatory logic for reading the Sonic Hedgehog Signaling gradient in the vertebrate neural tube
-
Balaskas N, Ribeiro A, Panovska J, Dessaud E, Sasai N, et al. (2012) Gene regulatory logic for reading the Sonic Hedgehog Signaling gradient in the vertebrate neural tube. Cell 148: 273-284.
-
(2012)
Cell
, vol.148
, pp. 273-284
-
-
Balaskas, N.1
Ribeiro, A.2
Panovska, J.3
Dessaud, E.4
Sasai, N.5
-
16
-
-
27644584608
-
Cardiac and CNS defects in a mouse with targeted disruption of Suppressor of fused
-
Cooper AF, Yu KP, Brueckner M, Brailey LL, Johnson L, et al. (2005) Cardiac and CNS defects in a mouse with targeted disruption of Suppressor of fused. Development 132: 4407-4417.
-
(2005)
Development
, vol.132
, pp. 4407-4417
-
-
Cooper, A.F.1
Yu, K.P.2
Brueckner, M.3
Brailey, L.L.4
Johnson, L.5
-
17
-
-
69449084098
-
The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling
-
Cheung HO-L, Zhang X, Riberio A, Mo R, Makino S, et al. (2009) The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling. Sci signal 2: ra29.
-
(2009)
Sci Signal
, vol.2
-
-
Cheung, H.O.-L.1
Zhang, X.2
Riberio, A.3
Mo, R.4
Makino, S.5
-
18
-
-
68149178664
-
The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development
-
Endoh-Yamagami S, Evangelista M, Wilson D, Wen X, Theunissen J-W, et al. (2009) The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development. Curr Biol 19: 1320-1326.
-
(2009)
Curr Biol
, vol.19
, pp. 1320-1326
-
-
Endoh-Yamagami, S.1
Evangelista, M.2
Wilson, D.3
Wen, X.4
Theunissen, J.-W.5
-
19
-
-
69449099121
-
Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling
-
Liem KF, He M, Ocbina PJR, Anderson KV, (2009) Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling. Proc Natl Acad Sci USA 106: 13377-13382.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 13377-13382
-
-
Liem, K.F.1
He, M.2
Ocbina, P.J.R.3
Anderson, K.V.4
-
20
-
-
31744451535
-
Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway
-
Svärd J, Heby-Henricson K, Henricson KH, Persson-Lek M, Rozell B, et al. (2006) Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway. Dev Cell 10: 187-197.
-
(2006)
Dev Cell
, vol.10
, pp. 187-197
-
-
Svärd, J.1
Heby-Henricson, K.2
Henricson, K.H.3
Persson-Lek, M.4
Rozell, B.5
-
21
-
-
31744450041
-
Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms
-
Barnfield PC, Zhang X, Thanabalasingham V, Yoshida M, Hui C-c, (2005) Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms. Differentiation 73: 397-405.
-
(2005)
Differentiation
, vol.73
, pp. 397-405
-
-
Barnfield, P.C.1
Zhang, X.2
Thanabalasingham, V.3
Yoshida, M.4
Hui, C.-c.5
-
22
-
-
69249245332
-
Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
-
Chen M-H, Wilson CW, Li YJ, Law KKL, Lu C-S, et al. (2009) Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved. Genes Dev 23: 1910-1928.
-
(2009)
Genes Dev
, vol.23
, pp. 1910-1928
-
-
Chen, M.-H.1
Wilson, C.W.2
Li, Y.J.3
Law, K.K.L.4
Lu, C.-S.5
-
23
-
-
77953050811
-
Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors
-
Wang C, Pan Y, Wang B, (2010) Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors. Development 137: 2001-2009.
-
(2010)
Development
, vol.137
, pp. 2001-2009
-
-
Wang, C.1
Pan, Y.2
Wang, B.3
-
24
-
-
77958508124
-
A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes
-
Tukachinsky H, Lopez LV, Salic A, (2010) A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes. J Cell Biol 191: 415-428.
-
(2010)
J Cell Biol
, vol.191
, pp. 415-428
-
-
Tukachinsky, H.1
Lopez, L.V.2
Salic, A.3
-
25
-
-
77950463564
-
The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
-
Humke EW, Dorn KV, Milenković L, Scott MP, Rohatgi R, (2010) The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins. Genes Dev 24: 670-682.
-
(2010)
Genes Dev
, vol.24
, pp. 670-682
-
-
Humke, E.W.1
Dorn, K.V.2
Milenković, L.3
Scott, M.P.4
Rohatgi, R.5
-
26
-
-
0033533714
-
Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1
-
Ding Q, Fukami S-i, Meng X, Nishixaki Y, Zhang X, et al. (1999) Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1. Curr Biol 9: 1119-1122.
-
(1999)
Curr Biol
, vol.9
, pp. 1119-1122
-
-
Ding, Q.1
Fukami, S.-i.2
Meng, X.3
Nishixaki, Y.4
Zhang, X.5
-
27
-
-
4544353067
-
Suppressor of fused regulates Gli activity through a dual binding mechanism
-
Merchant M, Vajdos FF, Ultsch M, Maun HR, Wendt U, et al. (2004) Suppressor of fused regulates Gli activity through a dual binding mechanism. Mol Cell Biol 24: 8627-8641.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8627-8641
-
-
Merchant, M.1
Vajdos, F.F.2
Ultsch, M.3
Maun, H.R.4
Wendt, U.5
-
28
-
-
80051536284
-
Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu
-
Hsu S-HC, Zhang X, Yu C, Li ZH, Wunder JS, et al. (2011) Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu. Development 138: 3791-3801.
-
(2011)
Development
, vol.138
, pp. 3791-3801
-
-
Hsu, S.-H.C.1
Zhang, X.2
Yu, C.3
Li, Z.H.4
Wunder, J.S.5
-
29
-
-
0033603209
-
A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventral spinal cord
-
Pierani A, Brenner-Morton S, Chiang C, Jessell TM, (1999) A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventral spinal cord. Cell 97: 903-915.
-
(1999)
Cell
, vol.97
, pp. 903-915
-
-
Pierani, A.1
Brenner-Morton, S.2
Chiang, C.3
Jessell, T.M.4
-
30
-
-
0141862018
-
Opposing FGF and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extension
-
Diez del Corral R, Olivera-Martinez I, Goriely A, Gale E, Maden M, et al. (2003) Opposing FGF and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extension. Neuron 40: 65-79.
-
(2003)
Neuron
, vol.40
, pp. 65-79
-
-
Diez del Corral, R.1
Olivera-Martinez, I.2
Goriely, A.3
Gale, E.4
Maden, M.5
-
31
-
-
0141862010
-
A requirement for retinoic acid-mediated transcriptional activation in ventral neural patterning and motor neuron specification
-
Novitch BG, Wichterle H, Jessell TM, Sockanathan S, (2003) A requirement for retinoic acid-mediated transcriptional activation in ventral neural patterning and motor neuron specification. Neuron 40: 81-95.
-
(2003)
Neuron
, vol.40
, pp. 81-95
-
-
Novitch, B.G.1
Wichterle, H.2
Jessell, T.M.3
Sockanathan, S.4
-
32
-
-
1942489385
-
Retinoic acid and the control of dorsoventral patterning in the avian spinal cord
-
Wilson L, Gale E, Chambers D, Maden M, (2004) Retinoic acid and the control of dorsoventral patterning in the avian spinal cord. Dev Biol 269: 433-446.
-
(2004)
Dev Biol
, vol.269
, pp. 433-446
-
-
Wilson, L.1
Gale, E.2
Chambers, D.3
Maden, M.4
-
33
-
-
80051500553
-
Tcf/Lef repressors differentially regulate Shh-Gli target gene activation thresholds to generate progenitor patterning in the developing CNS
-
Wang H, Lei Q, Oosterveen T, Ericson J, Matise MP, (2011) Tcf/Lef repressors differentially regulate Shh-Gli target gene activation thresholds to generate progenitor patterning in the developing CNS. Development 138: 3711-3721.
-
(2011)
Development
, vol.138
, pp. 3711-3721
-
-
Wang, H.1
Lei, Q.2
Oosterveen, T.3
Ericson, J.4
Matise, M.P.5
-
34
-
-
73349130440
-
Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate
-
Pospisilik JA, Schramek D, Schnidar H, Cronin SJF, Nehme NT, et al. (2010) Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. Cell 140: 148-160.
-
(2010)
Cell
, vol.140
, pp. 148-160
-
-
Pospisilik, J.A.1
Schramek, D.2
Schnidar, H.3
Cronin, S.J.F.4
Nehme, N.T.5
-
35
-
-
0035958941
-
Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R asymmetry by the mouse node
-
Zhang XM, Ramalho-Santos M, McMahon AP, (2001) Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R asymmetry by the mouse node. Cell 106: 781-792.
-
(2001)
Cell
, vol.106
, pp. 781-792
-
-
Zhang, X.M.1
Ramalho-Santos, M.2
McMahon, A.P.3
-
36
-
-
0031020221
-
Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development
-
Mo R, Freer AM, Zinyk DL, Crackower MA, Michaud J, et al. (1997) Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development. Development 124: 113-123.
-
(1997)
Development
, vol.124
, pp. 113-123
-
-
Mo, R.1
Freer, A.M.2
Zinyk, D.L.3
Crackower, M.A.4
Michaud, J.5
|