Capillarisin inhibits iNOS, COX-2 expression, and proinflammatory cytokines in LPS-induced RAW 264.7 macrophages via the suppression of ERK, JNK, and NF-κB activation

Immunopharmacology and Immunotoxicology

Volumn 35, Issue 1, 2013, Pages 34-42

  Han, Suckbae ^a   Lee, Jong Hyun ^a   Kim, Chulwon ^a   Nam, Dongwoo ^a   Chung, Won Seok ^a   Lee, Seok Geun ^a   Ahn, Kyoo Seok ^a   Cho, Somi K ^b   Cho, Moonjae ^c   Ahn, Kwang Seok ^a  

^a Kyung Hee University   (South Korea)

^b Jeju National University   (South Korea)

^c Jeju National University School of Medicine   (South Korea)

Author keywords

Capillarisin; Cyclooxygenase 2; Inflammation; NF B; Nitric oxide

Indexed keywords

ANTIINFLAMMATORY AGENT; ARTEMISIA CAPILLARIS EXTRACT; CAPILLARISIN; CYCLOOXYGENASE 2; FLAVONE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN E2; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTEMISIA CAPILLARIS; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; ENZYME REPRESSION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CELL LINE; CHROMONES; CYCLOOXYGENASE 2; DINOPROSTONE; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

ARTEMISIA CAPILLARIS; ASTERACEAE;

EID: 84869171007     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.3109/08923973.2012.736522     Document Type: Article

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