Co-regulation between cyclo-oxygenase-2 and inducible nitric oxide synthase expression in the time-course of murine inflammation

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 361, Issue 1, 2000, Pages 98-106

  Posadas, Inmaculada ^a   Terencio, M Carmen ^a   Guillén, Isabel ^a   Ferrándiz, M Luisa ^a   Coloma, Julio ^a   Payá, Miguel ^a   Alcaraz, M José ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Co regulation; Cyclo oxygenase 2 inducible nitric oxide synthase; Inflammation; Murine

Indexed keywords

AMINOGUANIDINE; COLCHICINE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DEXAMETHASONE; INDOMETACIN; LEUKOTRIENE B4; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN E2; ZYMOSAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME REGULATION; FEMALE; INFLAMMATION; LEUKOCYTE MIGRATION; MACROPHAGE; MOUSE; NONHUMAN;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; COLCHICINE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DEXAMETHASONE; DINOPROSTONE; EICOSANOIDS; ENZYME INDUCTION; EXUDATES AND TRANSUDATES; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; INFLAMMATION; ISOENZYMES; LEUKOCYTES; MICE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; TIME FACTORS; ZYMOSAN;

EID: 0033971576     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002109900150     Document Type: Article

References (57)

1. Aeberhard EE, Henderson SA, Arabolos NS, Griscavage JM, Castro FE, Barrett CT, Ignarro LJ (1995) Nonsteroidal anti-inflammatory drugs inhibit expression of the inducible nitric oxide synthase gene. Biochem Biophys Res Commun 208:1053-1059
2. Amin AR, Attur M, Patel RN, Thakker GD, Marshall PJ, Rediske J, Stuchin SA, Patel IR, Abramson SB (1997) Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. J Clin Invest 99:1231-1237
3. Bishop-Bailey D, Larkin SW, Warner TD, Chen G, Mitchell JA (1997) Characterization of the induction of nitric oxide synthase and cyclo-oxygenase in rat aorta in organ culture. Br J Pharmacol 121:125-133
4. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
5. 2 synthase are markedly affected by glutathione and glutathione peroxidase(s). Biochemistry 34:3325-3337
6. Connor JR, Manning PT, Settle SL, Moore WM, Jerome GM, Webber RK, Tjoeng FS, Currie MG (1995) Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase. Eur J Pharmacol 273:15-24
7. Crofford LJ (1997) COX-1 and COX-2 tissue expression: implications and predictions. J Rheumatol 24 Suppl 49:15-19
8. Demiryurek AT, Cakici I, Kanzik I (1998) Peroxynitrite: a putative cytotoxin. Pharmacol Toxicol 82:113-117
9. Edwards JCW, Sedgwick AD, Willoughby DA (1981) The formation of a structure with the features of synovial lining by subcutaneous injection of air: an in vivo tissue culture system. J Pathol 134:147-156
10. Ferrándiz ML, Foster SJ (1991) Tumour necrosis factor production in a rat air pouch model of inflammation: role of eicosanoids. Agents Actions 32:289-294
11. 2 synthase (cyclooxygenase) in human monocytes. J Biol Chem 265:16737-16740
12. 2 of cytokine-elicited nitric oxide synthesis in rat liver macrophages. Biol Chem Hoppe-Seyler 373:897-902
13. Habib A, Bernard C, Lebret M, Créminon C, Esposito B, Tedgui A, Maclouf J (1997) Regulation of the expression of cyclooxygenase-2 by nitric oxide in rat peritoneal macrophages. J Immunol 158:3845-3851
14. Honoré P, Chapman V, Buritova J, Besson J-M (1995) Reduction of carrageenin oedema and the associated c-Fos expression in the rat lumbar spinal cord by nitric oxide synthase inhibitor. Br J Pharmacol 114:77-84
15. Ialenti A, Moncada S, Di Rosa M (1993) Modulation of adjuvant arthritis by endogenous nitric oxide. Br J Pharmacol 110:701-705
16. 2 production by vascular smooth muscle cells. Biochem Biophys Res Commun 194:420-424
17. Iuvone T, Carnuccio R, Di Rosa M (1994) Modulation of granuloma formation by endogenous nitric oxide. Eur J Pharmacol 265:89-92
18. -) regulatory pathways. J Immunol 157:2129-2135
19. Kang RY, Freire Moar J, Sigal E, Chu CQ (1996) Expression of cyclooxygenase-2 in human and an animal model of rheumatoid arthritis. Br J Rheumatol 35:711-718
20. Kaur H, Halliwell B (1994) Evidence for nitric oxide-mediated oxidative damage in chronic inflammation. Nitrotyrosine in serum and synovial fluid from rheumatoid patients. FEBS Lett 350:9-12
21. Knowles RG, Moncada S (1994) Nitric oxide synthases in mammals. Biochem J 298:249-258
22. Knowles RG, Merrett M, Salter M, Moncada S (1990) Differential induction of brain, lung and liver nitric oxide synthase by endotoxin in the rat. Biochem J 270:833-836
23. Konno S, Tsurufuji S (1983) Induction of zymosan-air-pouch inflammation in rats and its characterization with reference to the effects of anticomplementary and anti-inflammatory agents. Br J Pharmacol 80:269-277
24. Marotta P, Sautebin L, Di Rosa M (1992) Modulation of the induction of nitric oxide synthase by eicosanoids in the murine macrophage cell line J774.2 cells. Br J Pharmacol 107:640-641
25. Masferrer JL, Zweifel BS, Needleman P. (1990) Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice. J Clin Invest 86:1375-1379
26. Masferrer JL, Zweifel BS, Manning PT, Hauser SD, Leahy KM, Smith WG, Isakson PC, Seibert K (1994) Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. Proc Natl Acad Sci USA 91:3228-3232
27. Michel T, Feron O (1997) Nitric oxide synthases: which, where, how, and why? J Clin Invest 100:2146-2152
28. Misko TP, Schilling RJ, Salvemini D, Moore WM, Currie MG (1993) A fluorometric assay for the measurement of nitrite in biological samples. Anal Biochem 214:11-16
29. Mitchell JA, Sheng H, Förstermann U, Murad F (1991) Characterization of nitric oxide synthases in non-adrenergic non-cholinergic nerve-containing tissue from the rat anococcygeus muscle. Br J Pharmacol 104:289-291
30. Moroney MA, Alcaraz MJ, Forder RA, Carey F, Hoult JRS (1988) Selectivity of neutrophil 5-lipoxygenase and cyclo-oxygenase inhibition by an anti-inflammatory flavonoid glycoside and related aglycone flavonoids. J Pharm Pharmacol 40:787-792
31. Mullet D, Fertel RH, Kniss D, Cox GW (1997) An increase in intracellular cyclic AMP modulates nitric oxide production in IFN-γ-treated macrophages. J Immunol 158:897-904
32. Nathan C (1997) Inducible nitric oxide synthase: what difference does it make? J Clin Invest 100:2417-2423
33. 2 on the induction of nitric oxide-and prostanoid-forming pathways in cultured rat mesangial cells. Biochem J 313:617-623
34. Palmer RMJ, Ferrige AG, Moncada S (1987) Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327:524-526
35. Payá M, García Pastor P, Coloma J, Alcaraz MJ (1997) Nitric oxide synthase and cyclo-oxygenase pathways in the inflammatory response induced by zymosan in the rat air pouch. Br J Pharmacol 120:1445-1452
36. Perretti M, Solito E, Parente L (1992) Evidence that endogenous interleukin-1 is involved in leukocyte migration in acute experimental inflammation in rats and mice. Agents Actions 35: 71-78
37. Perretti M, Szabó C, Thiemermann C (1995) Effect of interleukin-4 and interleukin-10 on leucocyte migration and nitric oxide production in the mouse. Br J Pharmacol 116:2251-2257
38. Radomski MW, Palmer RMJ, Moncada S (1990) Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells. Proc Natl Acad Sci USA 87:10043-10047
39. Rao TS, Currie JL, Shaffer AF, Isakson PC (1994) In vivo characterization of zymosan-induced mouse peritoneal inflammation. J Pharmacol Exp Ther 269:917-925
40. 6-(1-iminoethyl)lysine on zymosan-induced plasma extravasation in rat skin. J Immunol 159:383-390
41. Ristimäki A, Garfinkel S, Wessendorf J, Maciag T, Hla T (1994) Induction of cyclooxygenase-2 by interleukin-1α. Evidence for post-transcriptional regulation Induction of cyclooxygenase-2 by interleukin-1α. Evidence for post-transcriptional regulation. J Biol Chem 269:11769-11775
42. Salvemini D, Seibert K, Masferrer J, Misko TP, Currie MG, Needleman P (1994) Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. J Clin Invest 93:1940-1947
43. Salvemini D, Settle SL, Masferrer JL, Seibert K, Currie MG, Needleman P (1995a) Regulation of prostaglandin production by nitric oxide; an in vivo analysis. Br J Pharmacol 114: 1171-1178
44. Salvemini D, Manning PT, Zweifel BS, Seibert K, Connor J, Currie MG, Needleman P, Masferrer JL (1995b) Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors. J Clin Invest 96:301-308
45. Salvemini D, Wang Z-Q, Wyatt PS, Bourdon DM, Marino MH, Manning PT, Currie MG (1996) Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. Br J Pharmacol 118:829-838
46. Sautebin L, Ialenti A, Ianaro A, Di Rosa M (1995) Modulation by nitric oxide of prostaglandin biosynthesis in the rat. Br J Pharmacol 114:323-328
47. Stefanovic-Racic M, Meyers K, Meschter C, Coffey JW, Hoffman RA, Evans CH (1994) N-monomethyl arginine, an inhibitor of nitric oxide synthase, suppresses the development of adjuvant arthritis in rats. Arthritis Rheum 37:1062-1069
48. Swierkosz TA, Mitchell JA, Warner TD, Botting RM, Vane JR (1995) Co-induction of nitric oxide synthase and cyclo-oxygenase: interactions between nitric oxide and prostanoids. Br J Pharmacol 114:1335-1342
49. Szabo C, Dawson VL (1998) Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion. Trends Pharmacol Sci 19:287-298
50. 2 negatively modulates induction of nitric oxide synthase by interleukin 1. Proc Natl Acad Sci USA 91:12168-12172
51. Tetsuka T, Daphna-Iken D, Miler BW, Guan Z, Baier LD, Morrison AR (1996) Nitric oxide amplifies interleukin 1-induced cyclooxygenase-2 expression in rat mesangial cells. J Clin Invest 97:2051-2056
52. Tomlinson A, Appleton I, Moore AR, Gilroy DW, Willis D, Mitchell JA, Willoughby DA (1994) Cyclo-oxygenase and nitric oxide synthase isoforms in rat carrageenin-induced pleurisy. Br J Pharmacol 113:693-698
53. G-monomethylarginine, reduces carrageenan-induced pleurisy in the rat. J Pharmacol Exp Ther 273:1295-1299
54. Vane JR, Mitchell JA, Appleton I, Tomlison A, Bishop-Bailey D, Croxtall J, Willoughby DA (1994) Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. Proc Natl Acad Sci USA 91:2046-2050
55. Wallace JL, Bak A, McKnight W, Asfaha S, Sharkey KA, MacNaughton WK (1998) Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: implications for gastrointestinal toxicity. Gastroenterology 115:101-109
56. Watkins DN, Garlepp MJ, Thompson PJ (1997) Regulation of the inducible cyclo-oxygenase pathway in human cultured airway epithelial (A549) cells by nitric oxide. Br J Pharmacol 121:1482-1488
57. Wright CD, Mülsch A, Busse R, Osswald H (1989) Generation of nitric oxide by human neutrophils. Biochem Biophys Res Commun 160:813-819