Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration

Journal of Cell Biology

Volumn 199, Issue 2, 2012, Pages 331-345

  Wang, Shujie ^a,b   Watanabe, Takashi ^a   Matsuzawa, Kenji ^a   Katsumi, Akira ^a   Kakeno, Mai ^a   Matsui, Toshinori ^a   Ye, Feng ^c   Sato, Kazuhide ^a   Murase, Kiyoko ^a   Sugiyama, Ikuko ^a,d   Kimura, Kazushi ^b   Mizoguchi, Akira ^b   Ginsberg, Mark H ^c   Collard, John G ^e   Kaibuchi, Kozo ^a,d  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; INTEGRIN; PROTEIN TIAM1; PROTEINASE ACTIVATED RECEPTOR; RAC1 PROTEIN; TALIN; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CELL MIGRATION; CELL SPREADING; COMPLEX FORMATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL ADHESION; CELL COMMUNICATION; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL MOVEMENT; CELL POLARITY; CERCOPITHECUS AETHIOPS; COS CELLS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEK293 CELLS; HELA CELLS; HUMANS; INTEGRINS; MEMBRANE PROTEINS; PROTEIN KINASE C; RAC1 GTP-BINDING PROTEIN; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TALIN; VERO CELLS;

EID: 84869129672     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201202041     Document Type: Article

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