Steroid-insensitive ERK1/2 activity drives CXCL8 synthesis and neutrophilia by airway smooth muscle

American Journal of Respiratory Cell and Molecular Biology

Volumn 45, Issue 5, 2011, Pages 984-990

  Robins, Stephanie ^a   Roussel, Lucie ^a   Schachter, Amanda ^a   Risse, Paul André ^a   Mogas, Andrea K ^a   Olivenstein, Ron ^b   Martin, James G ^a   Hamid, Qutayba ^a   Rousseau, Simon ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Airway smooth muscle cells; ERK; MAPK; p38; Severe asthma

Indexed keywords

BECLOMETASONE; CORTICOSTEROID; DEXAMETHASONE; FLUTICASONE PROPIONATE PLUS SALMETEROL; FLUTICASONE PROPIONATE PLUS SALMETEROL XINAFOATE; FORMOTEROL; GLUCOCORTICOID; INTERLEUKIN 17; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; MONTELUKAST; SALBUTAMOL; THEOPHYLLINE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; ASTHMA; BREATHING MUSCLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG RESISTANCE; ENDOTHELIUM CELL; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; LUNG BIOPSY; MALE; NEUTROPHILIA; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SMOOTH MUSCLE; UPREGULATION;

ADULT; AGED; AGED, 80 AND OVER; ANTI-ASTHMATIC AGENTS; ASTHMA; CELLS, CULTURED; DUAL SPECIFICITY PHOSPHATASE 1; FEMALE; GLUCOCORTICOIDS; HUMANS; INTERLEUKIN-8; MALE; MAP KINASE SIGNALING SYSTEM; MIDDLE AGED; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; NEUTROPHILS; SEVERITY OF ILLNESS INDEX; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; YOUNG ADULT;

EID: 80555143027     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2010-0450OC     Document Type: Article

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