Interleukin-17A induction of angiogenesis, cell migration, and cytoskeletal rearrangement

Arthritis and Rheumatism

Volumn 63, Issue 11, 2011, Pages 3263-3273

  Moran, Ellen M ^a   Connolly, Mary ^a   Gao, Wei ^a   McCormick, Jennifer ^a   Fearon, Ursula ^a   Veale, Douglas J ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CHEMOTACTIC FACTOR; F ACTIN; IMMUNOGLOBULIN G; INTERLEUKIN 17; MATRIGEL; MONOCYTE CHEMOTACTIC PROTEIN 1; RAC1 PROTEIN;

ANGIOGENESIS; ARTICLE; CELL INVASION; CELL MIGRATION; CLINICAL ARTICLE; CYTOSKELETON; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; GROWTH RELATED ONCOGENE ALPHA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; ONCOGENE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; UPREGULATION; WESTERN BLOTTING;

ARTHRITIS, RHEUMATOID; CELL MOVEMENT; CYTOSKELETON; FIBROBLASTS; HUMANS; INTERLEUKIN-17; NEOVASCULARIZATION, PHYSIOLOGIC; SYNOVIAL MEMBRANE;

EID: 80155211550     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.30582     Document Type: Article

References (50)

1. Koenders MI, Joosten LA, van den Berg WB,. Potential new targets in arthritis therapy: interleukin (IL)-17 and its relation to tumour necrosis factor and IL-1 in experimental arthritis. Ann Rheum Dis 2006; 65: 29-33.
2. Moran E, Mullan R, McCormick J, Connolly M, Sullivan O, FitzGerald O, et al. Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-α, oncostatin M and response to biologic therapies. Arthritis Res Ther 2009; 11: R113.
3. Kehlen A, Thiele K, Riemann D, Langner J,. Expression, modulation and signalling of IL-17 receptor in fibroblast-like synoviocytes of patients with rheumatoid arthritis. Clin Exp Immunol 2002; 127: 539-46. (Pubitemid 34437828)
4. Honorati MC, Meliconi R, Pulsatelli L, Cane S, Frizziero L, Facchini A,. High in vivo expression of interleukin-17 receptor in synovial endothelial cells and chondrocytes from arthritis patients. Rheumatology (Oxford) 2001; 40: 522-7.
5. Hueber AJ, Asquith DL, Miller AM, Reilly J, Kerr S, Leipe J, et al. Cutting edge: mast cells express IL-17A in rheumatoid arthritis synovium. J Immunol 2010; 184: 3336-40.
6. Genovese MC, Van den Bosch F, Roberson SA, Bojin S, Biagini IM, Ryan P, et al. LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a phase I randomized, double-blind, placebo-controlled, proof-of-concept study. Arthritis Rheum 2010; 62: 929-39.
7. Szekanecz Z, Koch AE,. Vascular involvement in rheumatic diseases: 'vascular rheumatology'. Arthritis Res Ther 2008; 10: 224.
8. Wang AZ, Wang JC, Fisher GW, Diamond HS,. Interleukin-1β-stimulated invasion of articular cartilage by rheumatoid synovial fibroblasts is inhibited by antibodies to specific integrin receptors and by collagenase inhibitors. Arthritis Rheum 1997; 40: 1298-307. (Pubitemid 27430142)
9. Horton MA,. The αvβ3 integrin "vitronectin receptor." Int J Biochem Cell Biol 1997; 29: 721-5.
10. Lamalice L, Le Boeuf F, Huot J,. Endothelial cell migration during angiogenesis. Circ Res 2007; 100: 782-94. (Pubitemid 46555683)
11. Numasaki M, Lotze MT, Sasaki H,. Interleukin-17 augments tumour necrosis factor-α-induced elaboration of proangiogenic factors from fibroblasts. Immunol Lett 2004; 93: 39-43. (Pubitemid 38591518)
12. Ryu S, Lee JH, Kim SI,. IL-17 increased the production of vascular endothelial growth factor in rheumatoid arthritis synoviocytes. Clin Rheumatol 2006; 25: 16-20.
13. Pickens SR, Volin MV, Mandelin AM, Kolls JK, Pope RM, Shahrara S,. IL-17 contributes to angiogenesis in rheumatoid arthritis. J Immunol 2010; 184: 3233-41.
14. Witowski J, Pawlaczyk K, Breborowicz A, Scheuren A, Kuzlan-Pawlaczyk M, Wisniewska J, et al. IL-17 stimulates intraperitoneal neutrophil infiltration through the release of GROα chemokine from mesothelial cells. J Immunol 2000; 165: 5814-21.
15. Miossec P,. IL-17 in rheumatoid arthritis: a new target for treatment or just another cytokine? Joint Bone Spine 2004; 71: 87-90. (Pubitemid 38407212)
16. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315-24. (Pubitemid 18091653)
17. Fearon U, Mullan R, Markham T, Connolly M, Sullivan S, Poole AR, et al. Oncostatin M induces angiogenesis and cartilage degradation in rheumatoid arthritis synovial tissue and human cartilage cocultures. Arthritis Rheum 2006; 54: 3152-62. (Pubitemid 44622086)
18. Fearon U, Griosios K, Fraser A, Reece R, Emery P, Jones PF, et al. Angiopoietins, growth factors, and vascular morphology in early arthritis. J Rheumatol 2003; 30: 260-8. (Pubitemid 36152587)
19. Pickens SR, Volin MV, Mandelin AM II, Kolls JK, Pope RM, Shahrara S,. IL-17 contributes to angiogenesis in rheumatoid arthritis. J Immunol 2010; 184: 3233-41.
20. Numasaki M, Fukushi J, Ono M, Narula SK, Zavodny PJ, Kudo T, et al. Interleukin-17 promotes angiogenesis and tumor growth. Blood 2003; 101: 2620-7. (Pubitemid 36857622)
21. Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, et al. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J Immunol 2005; 175: 6177-89. (Pubitemid 41508106)
22. Sweeney SE, Firestein GS,. Rheumatoid arthritis: regulation of synovial inflammation. Int J Biochem Cell Biol 2004; 36: 372-8. (Pubitemid 37542434)
23. H17 cells in asthma and COPD. Annu Rev Physiol 2010; 72: 495-516.
24. Awane M, Andres PG, Li DJ, Reinecker HC,. NF-IκB-inducing kinase is a common mediator of IL-17-, TNF-α-, and IL-1β-induced chemokine promoter activation in intestinal epithelial cells. J Immunol 1999; 162: 5337-44. (Pubitemid 29307140)
25. Laan M, Cui ZH, Hoshino H, Lotvall J, Sjostrand M, Gruenert DC, et al. Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways. J Immunol 1999; 162: 2347-52. (Pubitemid 29288861)
26. Liang SC, Long AJ, Bennett F, Whitters MJ, Karim R, Collins M, et al. An IL-17F/A heterodimer protein is produced by mouse Th17 cells and induces airway neutrophil recruitment. J Immunol 2007; 179: 7791-9.
27. Koch AE, Kunkel SL, Shah MR, Hosaka S, Halloran MM, Haines GK, et al. Growth-related gene product α: a chemotactic cytokine for neutrophils in rheumatoid arthritis. J Immunol 1995; 155: 3660-6.
28. Koch AE, Kunkel SL, Harlow LA, Johnson B, Evanoff HL, Haines GK, et al. Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis. J Clin Invest 1992; 90: 772-9.
29. Garcia-Vicuna R, Gomez-Gaviro V, Dominguez-Luis MJ, Pec MK, Gonzalez-Alvaro I, Alvaro-Gracia JM, et al. CC and CXC chemokine receptors mediate migration, proliferation, and matrix metalloproteinase production by fibroblast-like synoviocytes from rheumatoid arthritis patients. Arthritis Rheum 2004; 50: 3866-77. (Pubitemid 39643933)
30. Yuan GH, Masuko-Hongo K, Nishioka K,. Role of chemokines/chemokine receptor systems in cartilage degradation. Drug News Perspect 2001; 14: 591-600. (Pubitemid 34202599)
31. Lisignoli G, Toneguzzi S, Grassi F, Piacentini A, Tschon M, Cristino S, et al. Different chemokines are expressed in human arthritic bone biopsies: IFN-γ and IL-6 differentially modulate IL-8, MCP-1 and RANTES production by arthritic osteoblasts. Cytokine 2002; 20: 231-8. (Pubitemid 37163476)
32. Lisignoli G, Toneguzzi S, Pozzi C, Piacentini A, Riccio M, Ferruzzi A, et al. Proinflammatory cytokines and chemokine production and expression by human osteoblasts isolated from patients with rheumatoid arthritis and osteoarthritis. J Rheumatol 1999; 26: 791-9. (Pubitemid 29195664)
33. Plater-Zyberk C, Hoogewerf AJ, Proudfoot AE, Power CA, Wells TN,. Effect of a CC chemokine receptor antagonist on collagen induced arthritis in DBA/1 mice. Immunol Lett 1997; 57: 117-20. (Pubitemid 27319323)
34. Boiardi L, Macchioni P, Meliconi R, Pulsatelli L, Facchini A, Salvarani C,. Relationship between serum RANTES levels and radiological progression in rheumatoid arthritis patients treated with methotrexate. Clin Exp Rheumatol 1999; 17: 419-25. (Pubitemid 29343625)
35. Iwamoto T, Okamoto H, Toyama Y, Momohara S,. Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients. FEBS J 2008; 275: 4448-55.
36. Kolls JK, Linden A,. Interleukin-17 family members and inflammation. Immunity 2004; 21: 467-76. (Pubitemid 39370503)
37. Eliceiri BP, Cheresh DA,. The role of αv integrins during angiogenesis: insights into potential mechanisms of action and clinical development. J Clin Invest 1999; 103: 1227-30. (Pubitemid 29218291)
38. Helfrich MH, Nesbitt SA, Lakkakorpi PT, Barnes MJ, Bodary SC, Shankar G, et al. β1 integrins and osteoclast function: involvement in collagen recognition and bone resorption. Bone 1996; 19: 317-28. (Pubitemid 26370834)
39. Brakebusch C, Bouvard D, Stanchi F, Sakai T, Fassler R,. Integrins in invasive growth. J Clin Invest 2002; 109: 999-1006. (Pubitemid 34408573)
40. Carr MW, Alon R, Springer TA,. The C-C chemokine MCP-1 differentially modulates the avidity of β1 and β2 integrins on T lymphocytes. Immunity 1996; 4: 179-87. (Pubitemid 26093777)
41. Weber C, Kitayama J, Springer TA,. Differential regulation of β1 and β2 integrin avidity by chemoattractants in eosinophils. Proc Natl Acad Sci U S A 1996; 93: 10939-44. (Pubitemid 26333096)
42. Rinaldi N, Schwarz EM, Weis D, Leppelmann JP, Lukoschek M, Keilholz U, et al. Increased expression of integrins on fibroblast-like synoviocytes from rheumatoid arthritis in vitro correlates with enhanced binding to extracellular matrix proteins. Ann Rheum Dis 1997; 56: 45-51. (Pubitemid 27060573)
43. Hauzenberger D, Klominek J, Sundqvist KG,. Functional specialization of fibronectin-binding β1-integrins in T lymphocyte migration. J Immunol 1994; 153: 960-71. (Pubitemid 24228487)
44. Laudanna C, Kim JY, Constantin G, Butcher E,. Rapid leukocyte integrin activation by chemokines. Immunol Rev 2002; 186: 37-46.
45. Chan A, Akhtar M, Brenner M, Zheng Y, Gulko PS, Symons M,. The GTPase Rac regulates the proliferation and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients. Mol Med 2007; 13: 297-304. (Pubitemid 47175039)
46. 3K. Nature 1997; 390: 632-6. (Pubitemid 28016201)
47. Huang H, Kim HJ, Chang EJ, Lee ZH, Hwang SJ, Kim HM, et al. IL-17 stimulates the proliferation and differentiation of human mesenchymal stem cells: implications for bone remodeling. Cell Death Differ 2009; 16: 1332-43.
48. Van Golen KL, Ying C, Sequeira L, Dubyk CW, Reisenberger T, Chinnaiyan AM, et al. CCL2 induces prostate cancer transendothelial cell migration via activation of the small GTPase Rac. J Cell Biochem 2008; 104: 1587-97.
49. Tanaka T, Terada M, Ariyoshi K, Morimoto K,. Monocyte chemoattractant protein-1/CC chemokine ligand 2 enhances apoptotic cell removal by macrophages through Rac1 activation. Biochem Biophys Res Commun 2010; 399: 677-82.
50. Kinashi T,. Intracellular signalling controlling integrin activation in lymphocytes. Nat Rev Immunol 2005; 5: 546-59. (Pubitemid 40961332)