Proteasomal inhibition in intracerebral hemorrhage: Neuroprotective and anti-inflammatory effects of bortezomib

Neuroscience Research

Volumn 58, Issue 1, 2007, Pages 12-18

  Sinn, Dong In ^a   Lee, Soon Tae ^a,b   Chu, Kon ^a   Jung, Keun Hwa ^a,c   Kim, Eun Hee ^a   Kim, Jeong Min ^a   Park, Dong Kyu ^a   Song, Eun Cheol ^a   Kim, Byung Su ^b   Yoon, Sung Soo ^b   Kim, Manho ^a   Roh, Jae Kyu ^a  

^a Seoul National University   (South Korea)

^b Seoul National University Hospital   (South Korea)

^c Korea Centers for Disease Control and Prevention   (South Korea)

Author keywords

Apoptosis; Bortezomib; Inflammation; Intracerebral hemorrhage; Proteasome inhibition; Ubiquitin proteasome system (UPS)

Indexed keywords

BORTEZOMIB; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MYELOPEROXIDASE; PROTEASOME; TUMOR NECROSIS FACTOR ALPHA;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN EDEMA; BRAIN HEMORRHAGE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DOSE COMPARISON; ENZYME INHIBITION; GENE EXPRESSION; HEMATOMA; MALE; MICROGLIA; MORTALITY; NEUROPROTECTION; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL MARKERS; BORONIC ACIDS; BRAIN EDEMA; CEREBRAL CORTEX; CEREBRAL HEMORRHAGE; CYTOKINES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENCEPHALITIS; GLIOSIS; INFLAMMATION MEDIATORS; MALE; MICROGLIA; NEUROPROTECTIVE AGENTS; NEUTROPHILS; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PYRAZINES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TREATMENT OUTCOME;

EID: 34247897136     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2007.01.006     Document Type: Article

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