Divergent synthesis of 2,6-diaryl-substituted 5,7,8-trimethyl-1,4- benzoxazines via microwave-promoted palladium-catalyzed Suzuki-Miyaura cross coupling and biological evaluation

Tetrahedron

Volumn 68, Issue 50, 2012, Pages 10302-10309

  Koini, Eftychia N ^a   Avlonitis, Nicolaos ^a,b   Martins Duarte, Erica S ^c   De Souza, Wanderley ^c,d   Vommaro, Rossiane C ^c   Calogeropoulou, Theodora ^a  

^a INSTITUTE OF BIOLOGY   (Greece)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^d INSTITUTO NACIONAL DE METROLOGIA   (Brazil)

Author keywords

2,6 Diaryl substituted 1,4 benzoxazines; 6 Halo 1,4 benzoxazines; Microwave assisted synthesis; Suzuki Miyaura cross coupling reaction; Toxoplasma gondii

Indexed keywords

ALKYL GROUP; BENZOXAZINE DERIVATIVE; BORONIC ACID DERIVATIVE; PALLADIUM; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; VINYL DERIVATIVE;

ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CATALYST; CHEMICAL REACTION; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; MICROWAVE IRRADIATION; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY; SUZUKI REACTION; TACHYZOITE; TOXOPLASMA GONDII;

TOXOPLASMA GONDII;

EID: 84869094930     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2012.10.009     Document Type: Article

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