-
1
-
-
0027248888
-
Prevention and treatment of allograft rejection in vivo by rapamycin: molecular and cellular mechanisms of action
-
Morris R.E. Prevention and treatment of allograft rejection in vivo by rapamycin: molecular and cellular mechanisms of action. Ann N Y Acad Sci 1993, 685:68-72.
-
(1993)
Ann N Y Acad Sci
, vol.685
, pp. 68-72
-
-
Morris, R.E.1
-
2
-
-
62349092099
-
The use of proliferation signal inhibitors in the prevention and treatment of allograft vasculopathy in heart transplantation
-
Delgado J.F., Manito N., Segovia J., Almenar L., Arizon J.M., Camprecios M., et al. The use of proliferation signal inhibitors in the prevention and treatment of allograft vasculopathy in heart transplantation. Transplant Rev (Orlando) 2009, 23:69-79.
-
(2009)
Transplant Rev (Orlando)
, vol.23
, pp. 69-79
-
-
Delgado, J.F.1
Manito, N.2
Segovia, J.3
Almenar, L.4
Arizon, J.M.5
Camprecios, M.6
-
3
-
-
0037030658
-
A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization
-
Morice M.C., Serruys P.W., Sousa J.E., Fajadet J., Ban H.E., Perin M., et al. A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization. N Engl J Med 2002, 346:1773-1780.
-
(2002)
N Engl J Med
, vol.346
, pp. 1773-1780
-
-
Morice, M.C.1
Serruys, P.W.2
Sousa, J.E.3
Fajadet, J.4
Ban, H.E.5
Perin, M.6
-
4
-
-
0035824907
-
Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling
-
Jonassen A.K., Sack M.N., Mjos O.D., Yellon D.M. Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling. Circ Res 2001, 89:1191-1198.
-
(2001)
Circ Res
, vol.89
, pp. 1191-1198
-
-
Jonassen, A.K.1
Sack, M.N.2
Mjos, O.D.3
Yellon, D.M.4
-
5
-
-
0042410540
-
Second window of protection following myocardial preconditioning: an essential role for PI3 kinase and p70S6 kinase
-
Kis A., Yellon D.M., Baxter G.F. Second window of protection following myocardial preconditioning: an essential role for PI3 kinase and p70S6 kinase. J Mol Cell Cardiol 2003, 35:1063-1071.
-
(2003)
J Mol Cell Cardiol
, vol.35
, pp. 1063-1071
-
-
Kis, A.1
Yellon, D.M.2
Baxter, G.F.3
-
6
-
-
80052147341
-
Differential roles of GSK-3beta during myocardial ischemia and ischemia/reperfusion
-
Zhai P., Sciarretta S., Galeotti J., Volpe M., Sadoshima J. Differential roles of GSK-3beta during myocardial ischemia and ischemia/reperfusion. Circ Res 2011, 109:502-511.
-
(2011)
Circ Res
, vol.109
, pp. 502-511
-
-
Zhai, P.1
Sciarretta, S.2
Galeotti, J.3
Volpe, M.4
Sadoshima, J.5
-
7
-
-
33746090919
-
Rapamycin confers preconditioning-like protection against ischemia-reperfusion injury in isolated mouse heart and cardiomyocytes
-
Khan S., Salloum F., Das A., Xi L., Vetrovec G.W., Kukreja R.C. Rapamycin confers preconditioning-like protection against ischemia-reperfusion injury in isolated mouse heart and cardiomyocytes. J Mol Cell Cardiol 2006, 41:256-264.
-
(2006)
J Mol Cell Cardiol
, vol.41
, pp. 256-264
-
-
Khan, S.1
Salloum, F.2
Das, A.3
Xi, L.4
Vetrovec, G.W.5
Kukreja, R.C.6
-
8
-
-
71649084135
-
Beneficial effects of mammalian target of rapamycin inhibition on left ventricular remodeling after myocardial infarction
-
Buss S.J., Muenz S., Riffel J.H., Malekar P., Hagenmueller M., Weiss C.S., et al. Beneficial effects of mammalian target of rapamycin inhibition on left ventricular remodeling after myocardial infarction. J Am Coll Cardiol 2009, 54:2435-2446.
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 2435-2446
-
-
Buss, S.J.1
Muenz, S.2
Riffel, J.H.3
Malekar, P.4
Hagenmueller, M.5
Weiss, C.S.6
-
9
-
-
53749100817
-
The myocardial JAK/STAT pathway: from protection to failure
-
Boengler K., Hilfiker-Kleiner D., Drexler H., Heusch G., Schulz R. The myocardial JAK/STAT pathway: from protection to failure. Pharmacol Ther 2008, 120:172-185.
-
(2008)
Pharmacol Ther
, vol.120
, pp. 172-185
-
-
Boengler, K.1
Hilfiker-Kleiner, D.2
Drexler, H.3
Heusch, G.4
Schulz, R.5
-
10
-
-
79952070542
-
A murine model of inducible, cardiac-specific deletion of STAT3: its use to determine the role of STAT3 in the upregulation of cardioprotective proteins by ischemic preconditioning
-
Bolli R., Stein A.B., Guo Y.R., Wang O.L., Rokosh G., Dawn B., et al. A murine model of inducible, cardiac-specific deletion of STAT3: its use to determine the role of STAT3 in the upregulation of cardioprotective proteins by ischemic preconditioning. J Mol Cell Cardiol 2011, 50:589-597.
-
(2011)
J Mol Cell Cardiol
, vol.50
, pp. 589-597
-
-
Bolli, R.1
Stein, A.B.2
Guo, Y.R.3
Wang, O.L.4
Rokosh, G.5
Dawn, B.6
-
11
-
-
0035979176
-
An essential role of the JAK-STAT pathway in ischemic preconditioning
-
Xuan Y.T., Guo Y., Han H., Zhu Y., Bolli R. An essential role of the JAK-STAT pathway in ischemic preconditioning. Proc Natl Acad Sci U S A 2001, 98:9050-9055.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 9050-9055
-
-
Xuan, Y.T.1
Guo, Y.2
Han, H.3
Zhu, Y.4
Bolli, R.5
-
12
-
-
4444377395
-
IL-6 plays an obligatory role in late preconditioning via JAK-STAT signaling and upregulation of iNOS and COX-2
-
Dawn B., Xuan Y.T., Guo Y., Rezazadeh A., Stein A.B., Hunt G., et al. IL-6 plays an obligatory role in late preconditioning via JAK-STAT signaling and upregulation of iNOS and COX-2. Cardiovasc Res 2004, 64:61-71.
-
(2004)
Cardiovasc Res
, vol.64
, pp. 61-71
-
-
Dawn, B.1
Xuan, Y.T.2
Guo, Y.3
Rezazadeh, A.4
Stein, A.B.5
Hunt, G.6
-
13
-
-
59849118216
-
Cell biology. Moonlighting in mitochondria
-
Myers M.G. Cell biology. Moonlighting in mitochondria. Science 2009, 323:723-724.
-
(2009)
Science
, vol.323
, pp. 723-724
-
-
Myers, M.G.1
-
14
-
-
45849120527
-
Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning
-
Suleman N., Somers S., Smith R., Opie L.H., Lecour S.C. Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning. Cardiovasc Res 2008, 79:127-133.
-
(2008)
Cardiovasc Res
, vol.79
, pp. 127-133
-
-
Suleman, N.1
Somers, S.2
Smith, R.3
Opie, L.H.4
Lecour, S.C.5
-
15
-
-
3342889421
-
Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury
-
Hilfiker-Kleiner D., Hilfiker A., Fuchs M., Kaminski K., Schaefer A., Schieffer B., et al. Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury. Circ Res 2004, 95:187-195.
-
(2004)
Circ Res
, vol.95
, pp. 187-195
-
-
Hilfiker-Kleiner, D.1
Hilfiker, A.2
Fuchs, M.3
Kaminski, K.4
Schaefer, A.5
Schieffer, B.6
-
16
-
-
0242268405
-
Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age
-
Jacoby J.J., Kalinowski A., Liu M.G., Zhang S.S., Gao Q., Chai G.X., et al. Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age. Proc Natl Acad Sci U S A 2003, 100:12929-12934.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12929-12934
-
-
Jacoby, J.J.1
Kalinowski, A.2
Liu, M.G.3
Zhang, S.S.4
Gao, Q.5
Chai, G.X.6
-
17
-
-
37849023059
-
Cardioprotection by ischemic postconditioning is lost in aged and STAT3-deficient mice
-
Boengler K., Buechert A., Heinen Y., Roeskes C., Hilfiker-Kleiner D., Heusch G., et al. Cardioprotection by ischemic postconditioning is lost in aged and STAT3-deficient mice. Circ Res 2008, 102:131-135.
-
(2008)
Circ Res
, vol.102
, pp. 131-135
-
-
Boengler, K.1
Buechert, A.2
Heinen, Y.3
Roeskes, C.4
Hilfiker-Kleiner, D.5
Heusch, G.6
-
18
-
-
33746859331
-
The JAK/STAT pathway is essential for opioid-induced cardioprotection: JAK2 as a mediator of STAT3, Akt, and GSK-3 beta
-
Gross E.R., Hsu A.K., Gross G.J. The JAK/STAT pathway is essential for opioid-induced cardioprotection: JAK2 as a mediator of STAT3, Akt, and GSK-3 beta. Am J Physiol Heart Circ Physiol 2006, 291:H827-H834.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
-
-
Gross, E.R.1
Hsu, A.K.2
Gross, G.J.3
-
19
-
-
78649324875
-
Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion
-
Boengler K., Hilfiker-Kleiner D., Heusch G., Schulz R. Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion. Basic Res Cardiol 2010, 105:771-785.
-
(2010)
Basic Res Cardiol
, vol.105
, pp. 771-785
-
-
Boengler, K.1
Hilfiker-Kleiner, D.2
Heusch, G.3
Schulz, R.4
-
20
-
-
81355146580
-
Mitochondrial STAT3 activation and cardioprotection by ischemic postconditioning in pigs with regional myocardial ischemia/reperfusion
-
Heusch G., Musiolik J., Gedik N., Skyschally A. Mitochondrial STAT3 activation and cardioprotection by ischemic postconditioning in pigs with regional myocardial ischemia/reperfusion. Circ Res 2011, 109:1302-1308.
-
(2011)
Circ Res
, vol.109
, pp. 1302-1308
-
-
Heusch, G.1
Musiolik, J.2
Gedik, N.3
Skyschally, A.4
-
21
-
-
59849101586
-
Function of mitochondrial Stat3 in cellular respiration
-
Wegrzyn J., Potla R., Chwae Y.J., Sepuri N.B., Zhang Q., Koeck T., et al. Function of mitochondrial Stat3 in cellular respiration. Science 2009, 323:793-797.
-
(2009)
Science
, vol.323
, pp. 793-797
-
-
Wegrzyn, J.1
Potla, R.2
Chwae, Y.J.3
Sepuri, N.B.4
Zhang, Q.5
Koeck, T.6
-
22
-
-
80051943914
-
Mitochondrial-targeted signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen species
-
Szczepanek K., Chen Q., Derecka M., Salloum F.N., Zhang Q., Szelag M., et al. Mitochondrial-targeted signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen species. J Biol Chem 2011, 286:29610-29620.
-
(2011)
J Biol Chem
, vol.286
, pp. 29610-29620
-
-
Szczepanek, K.1
Chen, Q.2
Derecka, M.3
Salloum, F.N.4
Zhang, Q.5
Szelag, M.6
-
23
-
-
66149148931
-
ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice
-
Das A., Salloum F.N., Xi L., Rao Y.J., Kukreja R.C. ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice. Am J Physiol Heart Circ Physiol 2009, 296:H1236-H1243.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
-
-
Das, A.1
Salloum, F.N.2
Xi, L.3
Rao, Y.J.4
Kukreja, R.C.5
-
24
-
-
41549085082
-
Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice
-
Salloum F.N., Abbate A., Das A., Houser J.E., Mudrick C.A., Qureshi I.Z., et al. Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice. Am J Physiol Heart Circ Physiol 2008, 294:H1398-H1406.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
Salloum, F.N.1
Abbate, A.2
Das, A.3
Houser, J.E.4
Mudrick, C.A.5
Qureshi, I.Z.6
-
25
-
-
16844382827
-
Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling
-
Das A., Xi L., Kukreja R.C. Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling. J Biol Chem 2005, 280:12944-12955.
-
(2005)
J Biol Chem
, vol.280
, pp. 12944-12955
-
-
Das, A.1
Xi, L.2
Kukreja, R.C.3
-
26
-
-
57649155045
-
Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta
-
Das A., Xi L., Kukreja R.C. Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta. J Biol Chem 2008, 283:29572-29585.
-
(2008)
J Biol Chem
, vol.283
, pp. 29572-29585
-
-
Das, A.1
Xi, L.2
Kukreja, R.C.3
-
27
-
-
67349242289
-
STAT3 deletion sensitizes cells to oxidative stress
-
Barry S.P., Townsend P.A., McCormick J., Knight R.A., Scarabelli T.M., Latchman D.S., et al. STAT3 deletion sensitizes cells to oxidative stress. Biochem Biophys Res Commun 2009, 385:324-329.
-
(2009)
Biochem Biophys Res Commun
, vol.385
, pp. 324-329
-
-
Barry, S.P.1
Townsend, P.A.2
McCormick, J.3
Knight, R.A.4
Scarabelli, T.M.5
Latchman, D.S.6
-
28
-
-
58149229482
-
Pretreatment with insulin before ischaemia reduces infarct size in Langendorff-perfused rat hearts
-
Fuglesteg B.N., Tiron C., Jonassen A.K., Mjos O.D., Ytrehus K. Pretreatment with insulin before ischaemia reduces infarct size in Langendorff-perfused rat hearts. Acta Physiol (Oxf) 2009, 195:273-282.
-
(2009)
Acta Physiol (Oxf)
, vol.195
, pp. 273-282
-
-
Fuglesteg, B.N.1
Tiron, C.2
Jonassen, A.K.3
Mjos, O.D.4
Ytrehus, K.5
-
29
-
-
3142566467
-
Cross-talk between the survival kinases during early reperfusion: its contribution to ischemic preconditioning
-
Hausenloy D.J., Mocanu M.M., Yellon D.M. Cross-talk between the survival kinases during early reperfusion: its contribution to ischemic preconditioning. Cardiovasc Res 2004, 63:305-312.
-
(2004)
Cardiovasc Res
, vol.63
, pp. 305-312
-
-
Hausenloy, D.J.1
Mocanu, M.M.2
Yellon, D.M.3
-
30
-
-
82555187786
-
A novel cardioprotective p38-MAPK/mTOR pathway
-
Hernandez G., Lal H., Fidalgo M., Guerrero A., Zalvide J., Force T., et al. A novel cardioprotective p38-MAPK/mTOR pathway. Exp Cell Res 2011, 317:2938-2949.
-
(2011)
Exp Cell Res
, vol.317
, pp. 2938-2949
-
-
Hernandez, G.1
Lal, H.2
Fidalgo, M.3
Guerrero, A.4
Zalvide, J.5
Force, T.6
-
31
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov D.D., Ali S.M., Sengupta S., Sheen J.H., Hsu P.P., Bagley A.F., et al. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol Cell 2006, 22:159-168.
-
(2006)
Mol Cell
, vol.22
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
Sheen, J.H.4
Hsu, P.P.5
Bagley, A.F.6
-
32
-
-
0030807080
-
Rapamycin inhibits alpha 1-adrenergic receptor-stimulated cardiac myocyte hypertrophy but not activation of hypertrophy-associated genes. Evidence for involvement of p70 S6 kinase
-
Boluyt M.O., Zheng J.S., Younes A., Long X., O'Neill L., Silverman H., et al. Rapamycin inhibits alpha 1-adrenergic receptor-stimulated cardiac myocyte hypertrophy but not activation of hypertrophy-associated genes. Evidence for involvement of p70 S6 kinase. Circ Res 1997, 81:176-186.
-
(1997)
Circ Res
, vol.81
, pp. 176-186
-
-
Boluyt, M.O.1
Zheng, J.S.2
Younes, A.3
Long, X.4
O'Neill, L.5
Silverman, H.6
-
33
-
-
33746699629
-
Inhibition of mTOR reduces chronic pressure-overload cardiac hypertrophy and fibrosis
-
Gao X.M., Wong G., Wang B., Kiriazis H., Moore X.L., Su Y.D., et al. Inhibition of mTOR reduces chronic pressure-overload cardiac hypertrophy and fibrosis. J Hypertens 2006, 24:1663-1670.
-
(2006)
J Hypertens
, vol.24
, pp. 1663-1670
-
-
Gao, X.M.1
Wong, G.2
Wang, B.3
Kiriazis, H.4
Moore, X.L.5
Su, Y.D.6
-
34
-
-
3042608187
-
Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload
-
McMullen J.R., Sherwood M.C., Tarnavski O., Zhang L., Dorfman A.L., Shioi T., et al. Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload. Circulation 2004, 109:3050-3055.
-
(2004)
Circulation
, vol.109
, pp. 3050-3055
-
-
McMullen, J.R.1
Sherwood, M.C.2
Tarnavski, O.3
Zhang, L.4
Dorfman, A.L.5
Shioi, T.6
-
35
-
-
0037382861
-
Rapamycin attenuates load-induced cardiac hypertrophy in mice
-
Shioi T., McMullen J.R., Tarnavski O., Converso K., Sherwood M.C., Manning W.J., et al. Rapamycin attenuates load-induced cardiac hypertrophy in mice. Circulation 2003, 107:1664-1670.
-
(2003)
Circulation
, vol.107
, pp. 1664-1670
-
-
Shioi, T.1
McMullen, J.R.2
Tarnavski, O.3
Converso, K.4
Sherwood, M.C.5
Manning, W.J.6
-
36
-
-
77955290360
-
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice
-
Zhang D., Contu R., Latronico M.V., Zhang J., Rizzi R., Catalucci D., et al. MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J Clin Invest 2010, 120:2805-2816.
-
(2010)
J Clin Invest
, vol.120
, pp. 2805-2816
-
-
Zhang, D.1
Contu, R.2
Latronico, M.V.3
Zhang, J.4
Rizzi, R.5
Catalucci, D.6
-
37
-
-
84863665544
-
Cardiac mTOR protects the heart against ischemia-reperfusion injury
-
Aoyagi T., Kusakari Y., Xiao C.Y., Inouye B.T., Takahashi M., Scherrer-Crosbie M., et al. Cardiac mTOR protects the heart against ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol 2012, 303:H75-H85.
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.303
-
-
Aoyagi, T.1
Kusakari, Y.2
Xiao, C.Y.3
Inouye, B.T.4
Takahashi, M.5
Scherrer-Crosbie, M.6
-
38
-
-
34548051362
-
Survival pathways in hypertrophy and heart failure: the gp130-STAT axis
-
Fischer P., Hilfiker-Kleiner D. Survival pathways in hypertrophy and heart failure: the gp130-STAT axis. Basic Res Cardiol 2007, 102:393-411.
-
(2007)
Basic Res Cardiol
, vol.102
, pp. 393-411
-
-
Fischer, P.1
Hilfiker-Kleiner, D.2
-
39
-
-
4043082106
-
Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning
-
Smith R.M., Suleman N., Lacerda L., Opie L.H., Akira S., Chien K.R., et al. Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning. Cardiovasc Res 2004, 63:611-616.
-
(2004)
Cardiovasc Res
, vol.63
, pp. 611-616
-
-
Smith, R.M.1
Suleman, N.2
Lacerda, L.3
Opie, L.H.4
Akira, S.5
Chien, K.R.6
-
40
-
-
0033838783
-
Activation of JAK/STAT pathway transduces cytoprotective signal in rat acute myocardial infarction
-
Negoro S., Kunisada K., Tone E., Funamoto M., Oh H., Kishimoto T., et al. Activation of JAK/STAT pathway transduces cytoprotective signal in rat acute myocardial infarction. Cardiovasc Res 2000, 47:797-805.
-
(2000)
Cardiovasc Res
, vol.47
, pp. 797-805
-
-
Negoro, S.1
Kunisada, K.2
Tone, E.3
Funamoto, M.4
Oh, H.5
Kishimoto, T.6
-
42
-
-
0037901025
-
Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway
-
Wierenga A.T., Vogelzang I., Eggen B.J., Vellenga E. Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway. Exp Hematol 2003, 31:398-405.
-
(2003)
Exp Hematol
, vol.31
, pp. 398-405
-
-
Wierenga, A.T.1
Vogelzang, I.2
Eggen, B.J.3
Vellenga, E.4
-
43
-
-
77951434599
-
STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transduction
-
Nguyen-Jackson H., Panopoulos A.D., Zhang H., Li H.S., Watowich S.S. STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transduction. Blood 2010, 115:3354-3363.
-
(2010)
Blood
, vol.115
, pp. 3354-3363
-
-
Nguyen-Jackson, H.1
Panopoulos, A.D.2
Zhang, H.3
Li, H.S.4
Watowich, S.S.5
-
44
-
-
34047250349
-
Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells
-
Saxena N.K., Sharma D., Ding X., Lin S., Marra F., Merlin D., et al. Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells. Cancer Res 2007, 67:2497-2507.
-
(2007)
Cancer Res
, vol.67
, pp. 2497-2507
-
-
Saxena, N.K.1
Sharma, D.2
Ding, X.3
Lin, S.4
Marra, F.5
Merlin, D.6
-
45
-
-
21244500204
-
Inhibition of GSK-3beta as a target for cardioprotection: the importance of timing, location, duration and degree of inhibition
-
Murphy E., Steenbergen C. Inhibition of GSK-3beta as a target for cardioprotection: the importance of timing, location, duration and degree of inhibition. Expert Opin Ther Targets 2005, 9:447-456.
-
(2005)
Expert Opin Ther Targets
, vol.9
, pp. 447-456
-
-
Murphy, E.1
Steenbergen, C.2
-
46
-
-
85047692700
-
Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore
-
Juhaszova M., Zorov D.B., Kim S.H., Pepe S., Fu Q., Fishbein K.W., et al. Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore. J Clin Invest 2004, 113:1535-1549.
-
(2004)
J Clin Invest
, vol.113
, pp. 1535-1549
-
-
Juhaszova, M.1
Zorov, D.B.2
Kim, S.H.3
Pepe, S.4
Fu, Q.5
Fishbein, K.W.6
-
47
-
-
67649882599
-
Role of glycogen synthase kinase-3beta in cardioprotection
-
Juhaszova M., Zorov D.B., Yaniv Y., Nuss H.B., Wang S., Sollott S.J. Role of glycogen synthase kinase-3beta in cardioprotection. Circ Res 2009, 104:1240-1252.
-
(2009)
Circ Res
, vol.104
, pp. 1240-1252
-
-
Juhaszova, M.1
Zorov, D.B.2
Yaniv, Y.3
Nuss, H.B.4
Wang, S.5
Sollott, S.J.6
-
48
-
-
0035413614
-
Glycogen synthase kinase-3: properties, functions, and regulation
-
Ali A., Hoeflich K.P., Woodgett J.R. Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev 2001, 101:2527-2540.
-
(2001)
Chem Rev
, vol.101
, pp. 2527-2540
-
-
Ali, A.1
Hoeflich, K.P.2
Woodgett, J.R.3
-
49
-
-
0037147327
-
ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons
-
Hetman M., Hsuan S.L., Habas A., Higgins M.J., Xia Z. ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons. J Biol Chem 2002, 277:49577-49584.
-
(2002)
J Biol Chem
, vol.277
, pp. 49577-49584
-
-
Hetman, M.1
Hsuan, S.L.2
Habas, A.3
Higgins, M.J.4
Xia, Z.5
-
50
-
-
33644855216
-
Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1
-
Maurer U., Charvet C., Wagman A.S., Dejardin E., Green D.R. Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol Cell 2006, 21:749-760.
-
(2006)
Mol Cell
, vol.21
, pp. 749-760
-
-
Maurer, U.1
Charvet, C.2
Wagman, A.S.3
Dejardin, E.4
Green, D.R.5
-
51
-
-
0037205315
-
Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development
-
Hardt S.E., Sadoshima J. Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development. Circ Res 2002, 90:1055-1063.
-
(2002)
Circ Res
, vol.90
, pp. 1055-1063
-
-
Hardt, S.E.1
Sadoshima, J.2
-
53
-
-
79952843143
-
GSK-3beta at the crossroads in the signalling of heart preconditioning: implication of mTOR and Wnt pathways
-
Vigneron F., Dos S.P., Lemoine S., Bonnet M., Tariosse L., Couffinhal T., et al. GSK-3beta at the crossroads in the signalling of heart preconditioning: implication of mTOR and Wnt pathways. Cardiovasc Res 2011, 90:49-56.
-
(2011)
Cardiovasc Res
, vol.90
, pp. 49-56
-
-
Vigneron, F.1
Dos, S.P.2
Lemoine, S.3
Bonnet, M.4
Tariosse, L.5
Couffinhal, T.6
-
54
-
-
3843150632
-
Aortic eNOS expression and phosphorylation in Apo-E knockout mice: differing effects of rapamycin and simvastatin
-
Naoum J.J., Zhang S., Woodside K.J., Song W., Guo Q., Belalcazar L.M., et al. Aortic eNOS expression and phosphorylation in Apo-E knockout mice: differing effects of rapamycin and simvastatin. Surgery 2004, 136:323-328.
-
(2004)
Surgery
, vol.136
, pp. 323-328
-
-
Naoum, J.J.1
Zhang, S.2
Woodside, K.J.3
Song, W.4
Guo, Q.5
Belalcazar, L.M.6
-
55
-
-
79952188007
-
Platelet-endothelial cell adhesion molecule-1 regulates endothelial NO synthase activity and localization through signal transducers and activators of transcription 3-dependent NOSTRIN expression
-
McCormick M.E., Goel R., Fulton D., Oess S., Newman D., Tzima E. Platelet-endothelial cell adhesion molecule-1 regulates endothelial NO synthase activity and localization through signal transducers and activators of transcription 3-dependent NOSTRIN expression. Arterioscler Thromb Vasc Biol 2011, 31:643-649.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 643-649
-
-
McCormick, M.E.1
Goel, R.2
Fulton, D.3
Oess, S.4
Newman, D.5
Tzima, E.6
-
56
-
-
0037168547
-
NOSTRIN: a protein modulating nitric oxide release and subcellular distribution of endothelial nitric oxide synthase
-
Zimmermann K., Opitz N., Dedio J., Renne C., Muller-Esterl W., Oess S. NOSTRIN: a protein modulating nitric oxide release and subcellular distribution of endothelial nitric oxide synthase. Proc Natl Acad Sci U S A 2002, 99:17167-17172.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 17167-17172
-
-
Zimmermann, K.1
Opitz, N.2
Dedio, J.3
Renne, C.4
Muller-Esterl, W.5
Oess, S.6
-
57
-
-
79957523514
-
Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes
-
Haghikia A., Missol-Kolka E., Tsikas D., Venturini L., Brundiers S., Castoldi M., et al. Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes. Eur Heart J 2011, 32:1287-1297.
-
(2011)
Eur Heart J
, vol.32
, pp. 1287-1297
-
-
Haghikia, A.1
Missol-Kolka, E.2
Tsikas, D.3
Venturini, L.4
Brundiers, S.5
Castoldi, M.6
-
58
-
-
0034711508
-
The late phase of preconditioning
-
Bolli R. The late phase of preconditioning. Circ Res 2000, 87:972-983.
-
(2000)
Circ Res
, vol.87
, pp. 972-983
-
-
Bolli, R.1
-
59
-
-
0033608951
-
Essential role of inducible nitric oxide synthase in monophosphoryl lipid A-induced late cardioprotection: evidence from pharmacological inhibition and gene knockout mice
-
Xi L., Jarrett N.C., Hess M.L., Kukreja R.C. Essential role of inducible nitric oxide synthase in monophosphoryl lipid A-induced late cardioprotection: evidence from pharmacological inhibition and gene knockout mice. Circulation 1999, 99:2157-2163.
-
(1999)
Circulation
, vol.99
, pp. 2157-2163
-
-
Xi, L.1
Jarrett, N.C.2
Hess, M.L.3
Kukreja, R.C.4
-
60
-
-
34548396883
-
Endothelial nitric oxide synthase plays an obligatory role in the late phase of ischemic preconditioning by activating the protein kinase C epsilon p44/42 mitogen-activated protein kinase pSer-signal transducers and activators of transcription 1/3 pathway
-
Xuan Y.T., Guo Y., Zhu Y., Wang O.L., Rokosh G., Bolli R. Endothelial nitric oxide synthase plays an obligatory role in the late phase of ischemic preconditioning by activating the protein kinase C epsilon p44/42 mitogen-activated protein kinase pSer-signal transducers and activators of transcription 1/3 pathway. Circulation 2007, 116:535-544.
-
(2007)
Circulation
, vol.116
, pp. 535-544
-
-
Xuan, Y.T.1
Guo, Y.2
Zhu, Y.3
Wang, O.L.4
Rokosh, G.5
Bolli, R.6
|