Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 22, 2003, Pages 12929-12934

  Jacoby, Jörg J ^a   Kalinowski, April ^a   Liu, Mu Gen ^a,d   Zhang, Samuel S M ^a   Gao, Qian ^a   Chai, Gui Xuan ^a   Ji, Lan ^a   Iwamoto, Yoshiki ^a,e   Li, En ^b   Schneider, Michael ^c   Russell, Kerry S ^a   Fu, Xin Yuan ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d FUWAI HOSPITAL   (China)

^e MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DOXORUBICIN; GLYCOPROTEIN GP 130; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DISEASE PREDISPOSITION; ECHOCARDIOGRAPHY; GENE DELETION; HEART DISEASE; HEART FAILURE; HEART INJURY; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART PROTECTION; HISTOLOGY; INFLAMMATION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE; WILD TYPE;

AGING; ALLELES; ANIMALS; DNA-BINDING PROTEINS; DOXORUBICIN; ECHOCARDIOGRAPHY; FIBROSIS; HEART FAILURE, CONGESTIVE; INFLAMMATION; MICE; MICE, KNOCKOUT; MUSCLE CELLS; MYOCARDIUM; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TUMOR NECROSIS FACTOR-ALPHA; VENTRICULAR FUNCTION, LEFT;

ANIMALIA;

EID: 0242268405     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2134694100     Document Type: Article

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