-
1
-
-
58149402403
-
Genetic effect on blood pressure is modulated by age: The Hypertension Genetic Epidemiology Network Study
-
Shi G, Gu CC, Kraja AT, et al. Genetic effect on blood pressure is modulated by age: the Hypertension Genetic Epidemiology Network Study. Hypertension 2009, 53: 35-41.
-
(2009)
Hypertension
, vol.53
, pp. 35-41
-
-
Shi, G.1
Gu, C.C.2
Kraja, A.T.3
-
3
-
-
41549085053
-
Identification of hypertension-susceptibility genes and pathways by a systemic multiple candidate gene approach: The millennium genome project for hypertension
-
DOI 10.1291/hypres.31.203
-
Kohara K, Tabara Y, Nakura J, et al. Identification of hypertension-susceptibility genes and pathways by a systemic multiple candidate gene approach: the millennium genome project for hypertension. Hypertens Res 2008, 31: 203-12. (Pubitemid 351461098)
-
(2008)
Hypertension Research
, vol.31
, Issue.2
, pp. 203-212
-
-
Kohara, K.1
Tabara, Y.2
Nakura, J.3
Imai, Y.4
Ohkubo, T.5
Hata, A.6
Soma, M.7
Nakayama, T.8
Umemura, S.9
Hirawa, N.10
Ueshima, H.11
Kita, Y.12
Ogihara, T.13
Katsuya, T.14
Takahashi, N.15
Tokunaga, K.16
Miki, T.17
-
4
-
-
0029949063
-
Leptin activation in hypothalamus
-
Woods AJ, Stock MJ. Leptin activation in hypothalamus. Nature 1996, 381: 745.
-
(1996)
Nature
, vol.381
, pp. 745
-
-
Woods, A.J.1
Stock, M.J.2
-
5
-
-
0035022513
-
Gender difference in the relationships among hyperleptinemia, hyperinsulinemia, and hypertension
-
DOI 10.1081/CEH-100102673
-
Takizawa H, Ura N, Saitoh S, et al. Gender difference in the relationships among hyperleptinemia, hyperinsulinemia, and hypertension. Clin Exp Hypertens 2001, 23: 357-68. (Pubitemid 32411069)
-
(2001)
Clinical and Experimental Hypertension
, vol.23
, Issue.4
, pp. 357-368
-
-
Takizawa, H.1
Ura, N.2
Saitoh, S.3
Wang, L.4
Higashiura, K.5
Takagi, S.6
Takada, M.7
Togashi, N.8
Nakano, M.9
Hayashi, Y.10
Shimamoto, K.11
-
6
-
-
53749097600
-
High-circulating leptin levels are associated with greater risk of hypertension in men independently of body mass and insulin resistance: Results of an eight-year follow-up study
-
Galletti F, D'Elia L, Barba G, et al. High-circulating leptin levels are associated with greater risk of hypertension in men independently of body mass and insulin resistance: results of an eight-year follow-up study. J Clin Endocrinol Metab 2008, 93: 3922-6.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 3922-3926
-
-
Galletti, F.1
D'Elia, L.2
Barba, G.3
-
7
-
-
0030830662
-
Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activity and blood pressure in normal rats
-
Dunbar JC, Hu Y, Lu H. Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activity and blood pressure in normal rats. Diabetes 1997, 46: 2040-3. (Pubitemid 27512093)
-
(1997)
Diabetes
, vol.46
, Issue.12
, pp. 2040-2043
-
-
Dunbar, J.C.1
Hu, Y.2
Lu, H.3
-
8
-
-
33749616410
-
Effect of genetic variation in the leptin gene promoter and the leptin receptor gene on obesity risk in a population-based case-control study in Spain
-
DOI 10.1007/s10654-006-9045-6
-
Portoles O, Sorli JV, Frances F, et al. Effect of genetic variation in the leptin gene promoter and the leptin receptor gene on obesity risk in a population-based case-control study in Spain. Eur J Epidemiol 2006, 21: 605-12. (Pubitemid 44546622)
-
(2006)
European Journal of Epidemiology
, vol.21
, Issue.8
, pp. 605-612
-
-
Portoles, O.1
Sorli, J.V.2
Frances, F.3
Coltell, O.4
Gonzalez, J.I.5
Saiz, C.6
Corella, D.7
-
9
-
-
0035073893
-
A single nucleotide polymorphism (SNP) in the leptin receptor is associated with BMI, fat mass and leptin levels in postmenopausal Caucasian women
-
DOI 10.1007/s004390100468
-
Quinton ND, Lee AJ, Ross RJ, Eastell R, Blakemore AI. A single nucleotide polymorphism (SNP) in the leptin receptor is associated with BMI, fat mass and leptin levels in postmenopausal Caucasian women. Hum Genet 2001, 108: 233-6. (Pubitemid 32293670)
-
(2001)
Human Genetics
, vol.108
, Issue.3
, pp. 233-236
-
-
Quinton, N.D.1
Lee, A.J.2
Ross, R.J.M.3
Eastell, R.4
Blakemore, A.I.F.5
-
10
-
-
33845508086
-
Polymorphism of the 3′-untranslated region of the leptin receptor gene, but not the adiponectin SNP45 polymorphism, predicts type 2 diabetes: A population-based study
-
DOI 10.2337/dc06-0355
-
Nannipieri M, Posadas R, Bonotti A, et al. Polymorphism of the 3′-untranslated region of the leptin receptor gene, but not the adiponectin SNP45 polymorphism, predicts type 2 diabetes: a population-based study. Diabetes Care 2006, 29: 2509-11. (Pubitemid 44912262)
-
(2006)
Diabetes Care
, vol.29
, Issue.11
, pp. 2509-2511
-
-
Nannipieri, M.1
Posadas, R.2
Bonotti, A.3
Williams, K.E.N.4
Gonzalez-Villalpando, C.5
Stern, M.P.6
Ferrannini, E.7
-
11
-
-
77958143645
-
Leptin receptor Lys109Arg and Gln223Arg polymorphisms are associated with early atherosclerosis
-
Saukko M, Kesaniemi YA, Ukkola O. Leptin receptor Lys109Arg and Gln223Arg polymorphisms are associated with early atherosclerosis. Metab Syndr Relat Disord 8: 425-30.
-
Metab Syndr Relat Disord
, vol.8
, pp. 425-430
-
-
Saukko, M.1
Kesaniemi, Y.A.2
Ukkola, O.3
-
12
-
-
72949119318
-
Leptin G-2548A and leptin receptor Q223R gene polymorphisms are not associated with obesity in Romanian subjects
-
Constantin A, Costache G, Sima AV, Glavce CS, Vladica M, Popov DL. Leptin G-2548A and leptin receptor Q223R gene polymorphisms are not associated with obesity in Romanian subjects. Biochem Biophys Res Commun 2010, 391: 282-6.
-
(2010)
Biochem Biophys Res Commun
, vol.391
, pp. 282-286
-
-
Constantin, A.1
Costache, G.2
Sima, A.V.3
Glavce, C.S.4
Vladica, M.5
Popov, D.L.6
-
13
-
-
0033694380
-
Hypertension in obesity and the leptin receptor gene locus
-
Rosmond R, Chagnon YC, Holm G, et al. Hypertension in obesity and the leptin receptor gene locus. J Clin Endocrinol Metab 2000, 85: 3126-31.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 3126-3131
-
-
Rosmond, R.1
Chagnon, Y.C.2
Holm, G.3
-
14
-
-
48349132166
-
Leptin-receptor polymorphisms relate to obesity through blunted leptin-mediated sympathetic nerve activation in a Caucasian male population
-
Masuo K, Straznicky NE, Lambert GW, et al. Leptin-receptor polymorphisms relate to obesity through blunted leptin-mediated sympathetic nerve activation in a Caucasian male population. Hypertens Res 2008, 31: 1093-100.
-
(2008)
Hypertens Res
, vol.31
, pp. 1093-1100
-
-
Masuo, K.1
Straznicky, N.E.2
Lambert, G.W.3
-
15
-
-
0021813187
-
Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
-
DOI 10.1007/BF00280883
-
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28: 412-9. (Pubitemid 15018832)
-
(1985)
Diabetologia
, vol.28
, Issue.7
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
-
16
-
-
0030876805
-
Receptor-mediated regional sympathetic nerve activation by leptin
-
Haynes WG, Morgan DA, Walsh SA, Mark AL, Sivitz WI. Receptor-mediated regional sympathetic nerve activation by leptin. J Clin Invest 1997, 100: 270-8. (Pubitemid 27349073)
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.2
, pp. 270-278
-
-
Haynes, W.G.1
Morgan, D.A.2
Walsh, S.A.3
Mark, A.L.4
Sivitz, W.I.5
-
17
-
-
79954701326
-
Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation
-
Harlan SM, Morgan DA, Agassandian K, et al. Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation. Circ Res 2011, 108: 808-12.
-
(2011)
Circ Res
, vol.108
, pp. 808-812
-
-
Harlan, S.M.1
Morgan, D.A.2
Agassandian, K.3
-
18
-
-
77952497025
-
Leptin-induced sympathetic nerve activation: Signaling mechanisms and cardiovascular consequences in obesity
-
Rahmouni K. Leptin-induced sympathetic nerve activation: signaling mechanisms and cardiovascular consequences in obesity. Curr Hypertens Rev 2010, 6: 104-209.
-
(2010)
Curr Hypertens Rev
, vol.6
, pp. 104-209
-
-
Rahmouni, K.1
-
19
-
-
68549133296
-
Association between the Gln223Arg polymorphism of the leptin receptor and metabolic syndrome in free-living community elderly
-
Gottlieb MG, Bodanese LC, Leite LE, et al. Association between the Gln223Arg polymorphism of the leptin receptor and metabolic syndrome in free-living community elderly. Metab Syndr Relat Disord 2009, 7: 341-8.
-
(2009)
Metab Syndr Relat Disord
, vol.7
, pp. 341-348
-
-
Gottlieb, M.G.1
Bodanese, L.C.2
Leite, L.E.3
-
20
-
-
12944257370
-
Pathophysiological role of leptin in obesity-related hypertension
-
Aizawa-Abe M, Ogawa Y, Masuzaki H, et al. Pathophysiological role of leptin in obesity-related hypertension. J Clin Invest 2000, 105: 1243-52. (Pubitemid 30266077)
-
(2000)
Journal of Clinical Investigation
, vol.105
, Issue.9
, pp. 1243-1252
-
-
Aizawa-Abe, M.1
Ogawa, Y.2
Masuzaki, H.3
Ebihara, K.4
Satoh, N.5
Iwai, H.6
Matsuoka, N.7
Hayashi, T.8
Hosoda, K.9
Inoue, G.10
Yoshimasa, Y.11
Nakao, K.12
-
21
-
-
18644375929
-
Association analysis of the Gln223Arg polymorphism in the human leptin receptor gene, and traits related to obesity in Mexican adolescents
-
DOI 10.1038/sj.jhh.1001824
-
Guízar-Mendoza JM, Amador-Licona N, Flores-Martínez SE, López-Cardona MG, Ahuatzin-Trémary R, Sánchez-Corona J. Association analysis of the Gln223Arg polymorphism in the human leptin receptor gene, and traits related to obesity in Mexican adolescents. J Hum Hypertens 2005, 19: 341-6. (Pubitemid 40662854)
-
(2005)
Journal of Human Hypertension
, vol.19
, Issue.5
, pp. 341-346
-
-
Guizar-Mendoza, J.M.1
Amador-Licona, N.2
Flores-Martinez, S.E.3
Lopez-Cardona, M.G.4
Ahuatzin-Tremary, R.5
Sanchez-Corona, J.6
-
22
-
-
0033794850
-
Human Leptin: From an Adipocyte Hormone to an Endocrine Mediator
-
Wauters M, Considine RV, Van Gaal LF. Human Leptin: From an Adipocyte Hormone to an Endocrine Mediator. Eur J Endocrinol 2000, 143: 293-311.
-
(2000)
Eur J Endocrinol
, vol.143
, pp. 293-311
-
-
Wauters, M.1
Considine, R.V.2
Van Gaal, L.F.3
-
23
-
-
0030965884
-
Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion
-
Emilsson V, Liu YL, Cawthorne MA, Morton NM, Davenport M. Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes 1997, 46: 313-6. (Pubitemid 27272267)
-
(1997)
Diabetes
, vol.46
, Issue.2
, pp. 313-316
-
-
Emilsson, V.1
Liu, Y.-L.2
Cawthorne, M.A.3
Morton, N.M.4
Davenport, M.5
-
24
-
-
30544443607
-
Genetic variation in leptin receptor gene is associated with type 2 diabetes and body weight: The Finnish Diabetes Prevention Study
-
DOI 10.1038/sj.ijo.0803024, PII 0803024
-
Salopuro T, Pulkkinen L, Lindström J, et al Finnish Diabetes Prevention Study Group. Genetic variation in leptin receptor gene is associated with type 2 diabetes and body weight: The Finnish Diabetes Prevention Study. Int J Obes (Lond) 2005, 29: 1245-51. (Pubitemid 43080304)
-
(2005)
International Journal of Obesity
, vol.29
, Issue.10
, pp. 1245-1251
-
-
Salopuro, T.1
Pulkkinen, L.2
Lindstrom, J.3
Eriksson, J.G.4
Valle, T.T.5
Hamalainen, H.6
Ilanne-Parikka, P.7
Keinanen-Kiukaanniemi, S.8
Tuomilehto, J.9
Laakso, M.10
Uusitupa, M.11
-
25
-
-
0034917636
-
Leptin receptor gene polymorphisms are associated with insulin in obese women with impaired glucose tolerance
-
DOI 10.1210/jc.86.7.3227
-
Wauters M, Mertens I, Rankinen T, Chagnon M, Bouchard C, Van Gaal L. Leptin receptor gene polymorphisms are associated with insulin in obese women with impaired glucose tolerance. J Clin Endocrinol Metab 2001, 86: 3227-32. (Pubitemid 32673492)
-
(2001)
Journal of Clinical Endocrinology and Metabolism
, vol.86
, Issue.7
, pp. 3227-3232
-
-
Wauters, M.1
Mertens, I.2
Rankinen, T.3
Chagnon, M.4
Bouchardt, C.5
Van Gaal, L.6
-
26
-
-
3042636426
-
Tyrosine phosphatase 1B and leptin receptor genes and their interaction in type 2 diabetes
-
DOI 10.1111/j.1365-2796.2004.01339.x
-
Santaniemi M, Ukkola O, Kesäniemi YA. Tyrosine phosphatase 1B and leptin receptor genes and their interaction in type 2 diabetes. J Intern Med 2004, 256: 48-55. (Pubitemid 38813619)
-
(2004)
Journal of Internal Medicine
, vol.256
, Issue.1
, pp. 48-55
-
-
Santaniemi, M.1
Ukkola, O.2
Kesaniemi, Y.A.3
-
27
-
-
31544469841
-
Polymorphisms in the leptin receptor (LEPR)--putative association with obesity and T2DM
-
Park KS, Shin HD, Park BL, et al. Polymorphisms in the leptin receptor (LEPR)--putative association with obesity and T2DM. J Hum Genet 2006, 51: 85-91.
-
(2006)
J Hum Genet
, vol.51
, pp. 85-91
-
-
Park, K.S.1
Shin, H.D.2
Park, B.L.3
-
28
-
-
35348965856
-
Obesity causes very low density lipoprotein clearance defects in low-density lipoprotein receptor-deficient mice
-
DOI 10.1016/j.jnutbio.2006.12.010, PII S0955286307000186
-
Coenen KR, Gruen ML, Hasty AH. Obesity causes very low density lipoprotein clearance defects in low-density lipoprotein receptor-deficient mice. J Nutr Biochem 2007, 18: 727-35. (Pubitemid 47600650)
-
(2007)
Journal of Nutritional Biochemistry
, vol.18
, Issue.11
, pp. 727-735
-
-
Coenen, K.R.1
Gruen, M.L.2
Hasty, A.H.3
-
29
-
-
48749130018
-
Leptin, soluble leptin receptor, lipid profiles, and LEPR gene polymorphisms in Thai children and adolescents
-
Popruk S, Tungtrongchitr R, Petmitr S, et al. Leptin, soluble leptin receptor, lipid profiles, and LEPR gene polymorphisms in Thai children and adolescents. Int J Vitam Nutr Res 2008, 78: 9-15.
-
(2008)
Int J Vitam Nutr Res
, vol.78
, pp. 9-15
-
-
Popruk, S.1
Tungtrongchitr, R.2
Petmitr, S.3
-
30
-
-
40449091302
-
Frequency of distribution of leptin receptor gene polymorphism in obstructive sleep apnea patients
-
Popko K, Gorska E, Wasik M, et al. Frequency of distribution of leptin receptor gene polymorphism in obstructive sleep apnea patients. J Physiol Pharmacol 2007, 58 (Suppl 5): 551-61. (Pubitemid 351346705)
-
(2007)
Journal of Physiology and Pharmacology
, vol.58
, Issue.SUPPL. 5
, pp. 551-561
-
-
Popko, K.1
Gorska, E.2
Wasik, M.3
Stoklosa, A.4
Plywaczewski, R.5
Winiarska, M.6
Gorecka, D.7
Sliwinski, P.8
Demkow, U.9
-
31
-
-
10744223625
-
Leptin receptor polymorphism is associated with serum lipid levels and impairment of cholesterol lowering effect by simvastatin in Japanese men
-
DOI 10.1016/S0168-8227(03)00163-3
-
Takahashi-Yasuno A, Masuzaki H, Miyawaki T, et al. Leptin receptor polymorphism is associated with serum lipid levels and impairment of cholesterol lowering effect by simvastatin in Japanese men. Diabetes Res Clin Pract 2003, 62: 169-75. (Pubitemid 37414983)
-
(2003)
Diabetes Research and Clinical Practice
, vol.62
, Issue.3
, pp. 169-175
-
-
Takahashi-Yasuno, A.1
Masuzaki, H.2
Miyawaki, T.3
Ogawa, Y.4
Matsuoka, N.5
Hayashi, T.6
Hosoda, K.7
Inoue, G.8
Yoshimasa, Y.9
Nakao, K.10
-
32
-
-
23744479594
-
A novel quantitative trait locus on chromosome 1 with pleiotropic effects on HDL-cholesterol and LDL particle size in hypertensive sibships
-
DOI 10.1016/j.amjhyper.2005.02.010, PII S0895706105000993
-
Kullo IJ, Turner ST, Boerwinkle E, Kardia SL, de Andrade M. A novel quantitative trait locus on chromosome 1 with pleiotropic effects on HDL-cholesterol and LDL particle size in hypertensive sibships. Am J Hypertens 2005, 18: 1084-90. (Pubitemid 41139907)
-
(2005)
American Journal of Hypertension
, vol.18
, Issue.8
, pp. 1084-1090
-
-
Kullo, I.J.1
Turner, S.T.2
Boerwinkle, E.3
Kardia, S.L.R.4
De Andrade, M.5
-
33
-
-
77949266531
-
The Q223R polymorphism in LEPR is associated with obesity in Pacific Islanders
-
Furusawa T, Naka I, Yamauchi T, et al. The Q223R polymorphism in LEPR is associated with obesity in Pacific Islanders. Hum Genet 2010, 127: 287-94.
-
(2010)
Hum Genet
, vol.127
, pp. 287-294
-
-
Furusawa, T.1
Naka, I.2
Yamauchi, T.3
-
34
-
-
67349258284
-
LEPR p.Q223R Polymorphism influences plasma leptin levels and body mass index in Tunisian obese patients
-
Ben Ali S, Kallel A, Sediri Y, et al. LEPR p.Q223R Polymorphism influences plasma leptin levels and body mass index in Tunisian obese patients. Arch Med Res 2009, 40: 186-90.
-
(2009)
Arch Med Res
, vol.40
, pp. 186-190
-
-
Ben Ali, S.1
Kallel, A.2
Sediri, Y.3
|