Evaluation of core-shell particle columns for ion-pair reversed-phase liquid chromatography analysis of oligonucleotides

Journal of Pharmaceutical and Biomedical Analysis

Volumn 72, Issue , 2013, Pages 25-32

  Biba, Mirlinda ^a,b   Welch, Christopher J ^a   Foley, Joe P ^b   Mao, Bing ^a   Vazquez, Enrique ^a   Arvary, Rebecca A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b DREXEL UNIVERSITY   (United States)

Author keywords

Core shell particle columns; Ion pair reversed phase liquid chromatography; Oligonucleotides; SiRNA; Sub 2 m core shell columns

Indexed keywords

OLIGONUCLEOTIDE;

ARTICLE; BASE PAIRING; PARTICLE SIZE; POROSITY; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY;

CHROMATOGRAPHY, REVERSE-PHASE; OLIGONUCLEOTIDES; PARTICLE SIZE;

EID: 84869075138     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.09.007     Document Type: Article

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