-
1
-
-
73349094086
-
Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
-
Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Kaewkungwal J, Chiu J, et al. (2009) Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N Engl J Med. 36: 2209-2220.
-
(2009)
N Engl J Med
, vol.36
, pp. 2209-2220
-
-
Rerks-Ngarm, S.1
Pitisuttithum, P.2
Nitayaphan, S.3
Kaewkungwal, J.4
Chiu, J.5
-
2
-
-
84859393693
-
Immune-correlates analysis of an HIV-1 vaccine efficacy trial
-
Haynes BF, Gilbert PB, McElrath MJ, Zolla-Pazner S, Tomaras GD, et al. (2012) Immune-correlates analysis of an HIV-1 vaccine efficacy trial. N Engl J Med. 366: 1275-1286.
-
(2012)
N Engl J Med
, vol.366
, pp. 1275-1286
-
-
Haynes, B.F.1
Gilbert, P.B.2
McElrath, M.J.3
Zolla-Pazner, S.4
Tomaras, G.D.5
-
3
-
-
77954663191
-
Innovative approaches to develop prophylactic and therapeutic vaccines against HIV/AIDS
-
(Guzman C.A. and Fuerstein G. Eds.), Chapter No. 14
-
Cafaro A, Macchia I, Maggiorella MT, Titti F, Ensoli B (2009). Innovative approaches to develop prophylactic and therapeutic vaccines against HIV/AIDS. In: Pharmaceutical Biotechnology (Guzman C.A. and Fuerstein G. Eds.), Chapter No. 14, 189-242.
-
(2009)
Pharmaceutical Biotechnology
, pp. 189-242
-
-
Cafaro, A.1
Macchia, I.2
Maggiorella, M.T.3
Titti, F.4
Ensoli, B.5
-
4
-
-
0033026062
-
Control of SHIV-89.6P-infection of cynomolgus monkeys by HIV-1 Tat protein vaccine
-
Cafaro A, Caputo A, Fracasso C, Maggiorella MT, Goletti D, et al. (1999) Control of SHIV-89.6P-infection of cynomolgus monkeys by HIV-1 Tat protein vaccine. Nat Med 5: 643-650.
-
(1999)
Nat Med
, vol.5
, pp. 643-650
-
-
Cafaro, A.1
Caputo, A.2
Fracasso, C.3
Maggiorella, M.T.4
Goletti, D.5
-
5
-
-
0033807492
-
SHIV89.6P pathogenicity in cynomolgus monkeys and control of viral replication and disease onset by human immunodeficiency virus type 1 Tat vaccine
-
Cafaro A, Caputo A, Maggiorella MT, Baroncelli S, Fracasso C, et al. (2000) SHIV89.6P pathogenicity in cynomolgus monkeys and control of viral replication and disease onset by human immunodeficiency virus type 1 Tat vaccine. J Med Primatol 29: 193-208.
-
(2000)
J Med Primatol
, vol.29
, pp. 193-208
-
-
Cafaro, A.1
Caputo, A.2
Maggiorella, M.T.3
Baroncelli, S.4
Fracasso, C.5
-
6
-
-
0035815501
-
Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89.6P)
-
Cafaro A, Titti F, Fracasso C, Maggiorella MT, Baroncelli S, et al. (2001) Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89.6P). Vaccine 19: 2862-2877.
-
(2001)
Vaccine
, vol.19
, pp. 2862-2877
-
-
Cafaro, A.1
Titti, F.2
Fracasso, C.3
Maggiorella, M.T.4
Baroncelli, S.5
-
7
-
-
77956629612
-
Impact of viral dose and major histocompatibility complex class IB haplotype on viral outcome in mauritian cynomolgus monkeys vaccinated with Tat upon challenge with simian/human immunodeficiency virus SHIV89.6P
-
Cafaro A, Bellino S, Titti F, Maggiorella MT, Sernicola L, et al. (2010) Impact of viral dose and major histocompatibility complex class IB haplotype on viral outcome in mauritian cynomolgus monkeys vaccinated with Tat upon challenge with simian/human immunodeficiency virus SHIV89.6P. J Virol 84: 8953-8958.
-
(2010)
J Virol
, vol.84
, pp. 8953-8958
-
-
Cafaro, A.1
Bellino, S.2
Titti, F.3
Maggiorella, M.T.4
Sernicola, L.5
-
8
-
-
4043096335
-
Long-term protection against SHIV89.6P replication in HIV-1 Tat vaccinated cynomolgus monkeys
-
Maggiorella MT, Baroncelli S, Michelini Z, Fanales-Belasio E, Moretti S, et al. (2004) Long-term protection against SHIV89.6P replication in HIV-1 Tat vaccinated cynomolgus monkeys. Vaccine 22: 3258-3269.
-
(2004)
Vaccine
, vol.22
, pp. 3258-3269
-
-
Maggiorella, M.T.1
Baroncelli, S.2
Michelini, Z.3
Fanales-Belasio, E.4
Moretti, S.5
-
9
-
-
65249088382
-
Containment of infection in tat vaccinated monkeys after rechallenge with a higher dose of SHIV89.6P(cy243)
-
Borsetti A, Baroncelli S, Maggiorella MT, Moretti S, Fanales-Belasio E, et al. (2009) Containment of infection in tat vaccinated monkeys after rechallenge with a higher dose of SHIV89.6P(cy243). Viral Immunol 22: 117-124.
-
(2009)
Viral Immunol
, vol.22
, pp. 117-124
-
-
Borsetti, A.1
Baroncelli, S.2
Maggiorella, M.T.3
Moretti, S.4
Fanales-Belasio, E.5
-
10
-
-
55249107608
-
Thetherapeutic phase I trial of the recombinant native HIV-1 Tat protein
-
Ensoli B, Fiorelli V, Ensoli F, Lazzarin A, Visintini R, et al. (2008) Thetherapeutic phase I trial of the recombinant native HIV-1 Tat protein. AIDS 22: 2207-2209.
-
(2008)
AIDS
, vol.22
, pp. 2207-2209
-
-
Ensoli, B.1
Fiorelli, V.2
Ensoli, F.3
Lazzarin, A.4
Visintini, R.5
-
11
-
-
70849124014
-
The preventive phase I trialwith the HIV-1 Tat-based vaccine
-
Ensoli B, Fiorelli V, Ensoli F, Lazzarin A, Visintini R, et al. (2009) The preventive phase I trialwith the HIV-1 Tat-based vaccine. Vaccine 28: 371-378.
-
(2009)
Vaccine
, vol.28
, pp. 371-378
-
-
Ensoli, B.1
Fiorelli, V.2
Ensoli, F.3
Lazzarin, A.4
Visintini, R.5
-
12
-
-
67349268940
-
Phase I therapeutic trial of the HIV-1 Tat protein and long term follow-up
-
Longo O, Tripiciano A, Fiorelli V, Bellino S, Scoglio A, et al. (2009) Phase I therapeutic trial of the HIV-1 Tat protein and long term follow-up. Vaccine 27: 3306-3312.
-
(2009)
Vaccine
, vol.27
, pp. 3306-3312
-
-
Longo, O.1
Tripiciano, A.2
Fiorelli, V.3
Bellino, S.4
Scoglio, A.5
-
13
-
-
78649720290
-
Tat Reduces Immune Activation and Loss of Regulatory T-Cells and Improves Immune Function in Subjects on HAART
-
Ensoli B, Bellino S, Tripiciano A, Longo O, Francavilla A, et al. (2010) Tat Reduces Immune Activation and Loss of Regulatory T-Cells and Improves Immune Function in Subjects on HAART. PLoS ONE 5: e13540.
-
(2010)
PLoS ONE
, vol.5
-
-
Ensoli, B.1
Bellino, S.2
Tripiciano, A.3
Longo, O.4
Francavilla, A.5
-
14
-
-
0025344596
-
Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients
-
Ensoli B, Barillari G, Salahuddin SZ, Gallo RC, Wong-Staal F, (1990) Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients. Nature 345: 84-86.
-
(1990)
Nature
, vol.345
, pp. 84-86
-
-
Ensoli, B.1
Barillari, G.2
Salahuddin, S.Z.3
Gallo, R.C.4
Wong-Staal, F.5
-
15
-
-
0027458469
-
Release, uptake, and effects of extracellular Human Immunodeficiency Virus type 1 Tat protein on cell growth and viral transactivation
-
Ensoli B, Buonaguro L, Barillari G, Fiorelli V, Gendelman R, et al. (1993) Release, uptake, and effects of extracellular Human Immunodeficiency Virus type 1 Tat protein on cell growth and viral transactivation. J Virol 67: 277-287.
-
(1993)
J Virol
, vol.67
, pp. 277-287
-
-
Ensoli, B.1
Buonaguro, L.2
Barillari, G.3
Fiorelli, V.4
Gendelman, R.5
-
16
-
-
0030862924
-
HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region
-
Chang HC, Samaniego F, Nair BC, Buonaguro L, Ensoli B, (1997) HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region. AIDS 11: 1421-1431.
-
(1997)
AIDS
, vol.11
, pp. 1421-1431
-
-
Chang, H.C.1
Samaniego, F.2
Nair, B.C.3
Buonaguro, L.4
Ensoli, B.5
-
17
-
-
0028036878
-
Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma
-
Ensoli B, Gendelman R, Markham P, Fiorelli V, Colombini S, et al. (1994) Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma. Nature 371: 674-680.
-
(1994)
Nature
, vol.371
, pp. 674-680
-
-
Ensoli, B.1
Gendelman, R.2
Markham, P.3
Fiorelli, V.4
Colombini, S.5
-
18
-
-
0029029058
-
Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120
-
Westendorp MO, Frank R, Ochsenbauer C, Stricker K, Dhein J, et al. (1995) Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature 375: 497-500.
-
(1995)
Nature
, vol.375
, pp. 497-500
-
-
Westendorp, M.O.1
Frank, R.2
Ochsenbauer, C.3
Stricker, K.4
Dhein, J.5
-
19
-
-
0034633618
-
Selective CXCR4 antagonism by Tat: implications for in vivo expansion of coreceptor use by HIV-1
-
Xiao H, Neuveut C, Tiffany HL, Benkirane M, Rich EA, et al. (2000) Selective CXCR4 antagonism by Tat: implications for in vivo expansion of coreceptor use by HIV-1. Proc Natl Acad Sci USA 97: 11466-11471.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11466-11471
-
-
Xiao, H.1
Neuveut, C.2
Tiffany, H.L.3
Benkirane, M.4
Rich, E.A.5
-
20
-
-
20144389037
-
Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope protein
-
Marchio S, Alfano M, Primo L, Gramaglia D, Butini L, et al. (2005) Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope protein. Blood 105: 2802-2811.
-
(2005)
Blood
, vol.105
, pp. 2802-2811
-
-
Marchio, S.1
Alfano, M.2
Primo, L.3
Gramaglia, D.4
Butini, L.5
-
21
-
-
77951498245
-
Phosphatidylinositol-(4,5)-bisphosphate enables efficient secretion of HIV-1 Tat by infected T-cells
-
Rayne F, Debaisieux S, Yezid H, Lin YL, Mettling C, et al. (2010) Phosphatidylinositol-(4,5)-bisphosphate enables efficient secretion of HIV-1 Tat by infected T-cells. EMBO J. 29: 1348-1362.
-
(2010)
EMBO J
, vol.29
, pp. 1348-1362
-
-
Rayne, F.1
Debaisieux, S.2
Yezid, H.3
Lin, Y.L.4
Mettling, C.5
-
22
-
-
0027220944
-
The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence
-
Barillari G, Gendelman R, Gallo RC, Ensoli B, (1993) The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence. Proc Natl Acad Sci U S A 90: 7941-7945.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 7941-7945
-
-
Barillari, G.1
Gendelman, R.2
Gallo, R.C.3
Ensoli, B.4
-
23
-
-
0033566297
-
The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor
-
Barillari G, Sgadari C, Fiorelli V, Samaniego F, Colombini S, et al. (1999) The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor. Blood 94: 663-672.
-
(1999)
Blood
, vol.94
, pp. 663-672
-
-
Barillari, G.1
Sgadari, C.2
Fiorelli, V.3
Samaniego, F.4
Colombini, S.5
-
24
-
-
0033566827
-
Inflammatory cytokines synergize with the HIV-1 Tat protein to promote angiogenesis and Kaposi's sarcoma via induction of basic fibroblast growth factor and the alpha v beta 3 integrin
-
Barillari G, Sgadari C, Palladino C, Gendelman R, Caputo A, et al. (1999) Inflammatory cytokines synergize with the HIV-1 Tat protein to promote angiogenesis and Kaposi's sarcoma via induction of basic fibroblast growth factor and the alpha v beta 3 integrin. J Immunol 163: 1929-1935.
-
(1999)
J Immunol
, vol.163
, pp. 1929-1935
-
-
Barillari, G.1
Sgadari, C.2
Palladino, C.3
Gendelman, R.4
Caputo, A.5
-
25
-
-
0036144393
-
Inflammation, immune reactivity, and angiogenesis in a severe combined immunodeficiency model of rheumatoid arthritis
-
Davis LS, Sackler M, Brezinschek RI, Lightfoot E, Bailey JL, et al. (2002) Inflammation, immune reactivity, and angiogenesis in a severe combined immunodeficiency model of rheumatoid arthritis. Am J Pathol 160: 357-367.
-
(2002)
Am J Pathol
, vol.160
, pp. 357-367
-
-
Davis, L.S.1
Sackler, M.2
Brezinschek, R.I.3
Lightfoot, E.4
Bailey, J.L.5
-
26
-
-
33646381864
-
Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis
-
Koning GA, Schiffelers RM, Wauben MH, Kok RJ, Mastrobattista E, et al. (2006) Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis. Arthritis Rheum 54: 1198-1208.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1198-1208
-
-
Koning, G.A.1
Schiffelers, R.M.2
Wauben, M.H.3
Kok, R.J.4
Mastrobattista, E.5
-
28
-
-
0027466377
-
A novel integrin specificity exemplified by binding of the alpha v beta 5 integrin to the basic domain of the HIV Tat protein and vitronectin
-
Vogel BE, Lee SJ, Hildebrand A, Craig W, Pierschbacher MD, et al. (1993) A novel integrin specificity exemplified by binding of the alpha v beta 5 integrin to the basic domain of the HIV Tat protein and vitronectin. J Cell Biol 121: 461-468.
-
(1993)
J Cell Biol
, vol.121
, pp. 461-468
-
-
Vogel, B.E.1
Lee, S.J.2
Hildebrand, A.3
Craig, W.4
Pierschbacher, M.D.5
-
29
-
-
0036136322
-
Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses
-
Fanales-Belasio E, Moretti S, Nappi F, Barillari G, Micheletti F, et al. (2002) Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses. J Immunol 168: 197-206.
-
(2002)
J Immunol
, vol.168
, pp. 197-206
-
-
Fanales-Belasio, E.1
Moretti, S.2
Nappi, F.3
Barillari, G.4
Micheletti, F.5
-
30
-
-
64849092816
-
HIV-1 Tat addresses dendritic cells to induce a predominant Th1-type adaptive immune response that appears prevalent in the asymptomatic stage of infection
-
Fanales-Belasio E, Moretti S, Fiorelli V, Tripiciano A, Pavone Cossut MR, et al. (2009) HIV-1 Tat addresses dendritic cells to induce a predominant Th1-type adaptive immune response that appears prevalent in the asymptomatic stage of infection. J Immunol 182: 2888-2897.
-
(2009)
J Immunol
, vol.182
, pp. 2888-2897
-
-
Fanales-Belasio, E.1
Moretti, S.2
Fiorelli, V.3
Tripiciano, A.4
Pavone Cossut, M.R.5
-
31
-
-
4644302152
-
HIV-1 tat protein modulates the generation of cytotoxic T cell epitopes by modifying proteasome composition and enzymatic activity
-
Gavioli R, Gallerani E, Fortini C, Fabris M, Bottoni A, et al. (2004) HIV-1 tat protein modulates the generation of cytotoxic T cell epitopes by modifying proteasome composition and enzymatic activity. J Immunol 173: 3838-3843.
-
(2004)
J Immunol
, vol.173
, pp. 3838-3843
-
-
Gavioli, R.1
Gallerani, E.2
Fortini, C.3
Fabris, M.4
Bottoni, A.5
-
32
-
-
37849043864
-
The Tat protein broadens T cell responses directed to the HIV-1 antigens Gag and Env: implications for the design of new vaccination strategies against AIDS
-
Gavioli R, Cellini S, Castaldello A, Voltan R, Gallerani E, et al. (2008) The Tat protein broadens T cell responses directed to the HIV-1 antigens Gag and Env: implications for the design of new vaccination strategies against AIDS. Vaccine 26: 727-737.
-
(2008)
Vaccine
, vol.26
, pp. 727-737
-
-
Gavioli, R.1
Cellini, S.2
Castaldello, A.3
Voltan, R.4
Gallerani, E.5
-
33
-
-
72949119184
-
Immobilized HIV-1 Tat protein promotes gene transfer via a transactivation-independent mechanism which requires binding of Tat to viral particles
-
Nappi F, Chiozzini C, Bordignon V, Borsetti A, Bellino S, et al. (2009) Immobilized HIV-1 Tat protein promotes gene transfer via a transactivation-independent mechanism which requires binding of Tat to viral particles. J Gene Med 11: 955-965.
-
(2009)
J Gene Med
, vol.11
, pp. 955-965
-
-
Nappi, F.1
Chiozzini, C.2
Bordignon, V.3
Borsetti, A.4
Bellino, S.5
-
34
-
-
0035114575
-
Antibodies against full-length Tat protein and some low-molecular-weight Tat-peptides correlate with low or undetectable viral load in HIV-1 seropositive patients
-
Re MC, Vignoli M, Furlini G, Gibellini D, Colangeli V, et al. (2001) Antibodies against full-length Tat protein and some low-molecular-weight Tat-peptides correlate with low or undetectable viral load in HIV-1 seropositive patients. J Clin Virol 21: 81-89.
-
(2001)
J Clin Virol
, vol.21
, pp. 81-89
-
-
Re, M.C.1
Vignoli, M.2
Furlini, G.3
Gibellini, D.4
Colangeli, V.5
-
35
-
-
0026081198
-
Contribution of antibody response to recombinant HIV-1 gene-encoded proucts nef, rev, tat, and protease in predicting development of AIDS in HIV-1-infected individuals
-
Reiss P, de Wolf F, Kuiken CL, de Ronde A, Dekker J, et al. (1991) Contribution of antibody response to recombinant HIV-1 gene-encoded proucts nef, rev, tat, and protease in predicting development of AIDS in HIV-1-infected individuals. J Acquir Immune Defic Syndr 4: 165-172.
-
(1991)
J Acquir Immune Defic Syndr
, vol.4
, pp. 165-172
-
-
Reiss, P.1
de Wolf, F.2
Kuiken, C.L.3
de Ronde, A.4
Dekker, J.5
-
36
-
-
0032057349
-
Antibodies to the HIV-1 Tat protein correlated with non progression to AIDS: a rationale for the use of Tat toxoid as an HIV-1 vaccine
-
Zagury JF, Sill A, Blattner W, Lachgar A, Le Buanec H, et al. (1998) Antibodies to the HIV-1 Tat protein correlated with non progression to AIDS: a rationale for the use of Tat toxoid as an HIV-1 vaccine. J Hum Virol 1: 282-292.
-
(1998)
J Hum Virol
, vol.1
, pp. 282-292
-
-
Zagury, J.F.1
Sill, A.2
Blattner, W.3
Lachgar, A.4
Le Buanec, H.5
-
37
-
-
0037228189
-
Antibodies to Tat and Vpr in the GRIV cohort: differential association with maintenance of long-term non progression status in HIV-1 infection
-
Richardson MW, Mirchandani J, Duong J, Grimaldo S, Kocieda V, et al. (2003) Antibodies to Tat and Vpr in the GRIV cohort: differential association with maintenance of long-term non progression status in HIV-1 infection. Biomed Pharmacother 57: 4-14.
-
(2003)
Biomed Pharmacother
, vol.57
, pp. 4-14
-
-
Richardson, M.W.1
Mirchandani, J.2
Duong, J.3
Grimaldo, S.4
Kocieda, V.5
-
38
-
-
20144389726
-
The presence of anti-Tat antibodies is predictive of long-term non progression to AIDS or severe immunodeficiency: findings in a cohort of HIV-1 seroconverters
-
Rezza G, Fiorelli V, Dorrucci M, Ciccozzi M, Tripiciano A, et al. (2005) The presence of anti-Tat antibodies is predictive of long-term non progression to AIDS or severe immunodeficiency: findings in a cohort of HIV-1 seroconverters. J Infect Dis 191: 1321-1324.
-
(2005)
J Infect Dis
, vol.191
, pp. 1321-1324
-
-
Rezza, G.1
Fiorelli, V.2
Dorrucci, M.3
Ciccozzi, M.4
Tripiciano, A.5
-
39
-
-
27844474248
-
Vaccines based on the native HIV Tat protein and on the combination of Tat and the structural HIV protein variant DeltaV2 Env
-
Ensoli B, Cafaro A, Caputo A, Fiorelli V, Ensoli F, et al. (2005) Vaccines based on the native HIV Tat protein and on the combination of Tat and the structural HIV protein variant DeltaV2 Env. Microbes Infect 7: 1392-1399.
-
(2005)
Microbes Infect
, vol.7
, pp. 1392-1399
-
-
Ensoli, B.1
Cafaro, A.2
Caputo, A.3
Fiorelli, V.4
Ensoli, F.5
-
40
-
-
33947380960
-
A replication-competent adenovirus-human immunodeficiency virus (Ad-HIV) tat and Ad-HIV env priming/Tat and envelope protein boosting regimen elicits enhanced protective efficacy against simian/human immunodeficiency virus SHIV89.6P challenge in rhesus macaques
-
Demberg T, Florese RH, Heath MJ, Larsen K, Kalisz I, et al. (2007) A replication-competent adenovirus-human immunodeficiency virus (Ad-HIV) tat and Ad-HIV env priming/Tat and envelope protein boosting regimen elicits enhanced protective efficacy against simian/human immunodeficiency virus SHIV89.6P challenge in rhesus macaques. J Virol 81: 3414-3427.
-
(2007)
J Virol
, vol.81
, pp. 3414-3427
-
-
Demberg, T.1
Florese, R.H.2
Heath, M.J.3
Larsen, K.4
Kalisz, I.5
-
41
-
-
79953211067
-
A combination HIV vaccine based on Tat and Env proteins was immunogenic and protected macaques from mucosal SHIV challenge in a pilot study
-
Ferrantelli F, Maggiorella MT, Schiavoni I, Sernicola L, Olivieri E, et al. (2011) A combination HIV vaccine based on Tat and Env proteins was immunogenic and protected macaques from mucosal SHIV challenge in a pilot study. Vaccine 29: 2918-2932.
-
(2011)
Vaccine
, vol.29
, pp. 2918-2932
-
-
Ferrantelli, F.1
Maggiorella, M.T.2
Schiavoni, I.3
Sernicola, L.4
Olivieri, E.5
-
42
-
-
9244262981
-
Nonstructural HIV proteins as targets for prophylactic or therapeutic vaccines
-
Ferrantelli F, Cafaro A, Ensoli B, (2004) Nonstructural HIV proteins as targets for prophylactic or therapeutic vaccines. Curr Opin Biotechnol 15: 543-556.
-
(2004)
Curr Opin Biotechnol
, vol.15
, pp. 543-556
-
-
Ferrantelli, F.1
Cafaro, A.2
Ensoli, B.3
-
43
-
-
0030832885
-
Inhibition of HIV-1 replication by a Tat transdominant negative mutant in human peripheral blood lymphocytes from healthy donors and HIV-1-infected patients
-
Rossi C, Balboni PG, Betti M, Marconi PC, Bozzini R, et al. (1997) Inhibition of HIV-1 replication by a Tat transdominant negative mutant in human peripheral blood lymphocytes from healthy donors and HIV-1-infected patients. Gene Ther 4: 1261-1269.
-
(1997)
Gene Ther
, vol.4
, pp. 1261-1269
-
-
Rossi, C.1
Balboni, P.G.2
Betti, M.3
Marconi, P.C.4
Bozzini, R.5
-
44
-
-
0141788494
-
Purification, characterization, and immunogenicity of a soluble trimeric envelope protein containing a partial deletion of the V2 loop derived from SF162, an R5-tropic human immunodeficiency virus type 1 isolate
-
Srivastava IK, Stamatatos L, Kan E, Vajdy M, Lian Y, et al. (2003) Purification, characterization, and immunogenicity of a soluble trimeric envelope protein containing a partial deletion of the V2 loop derived from SF162, an R5-tropic human immunodeficiency virus type 1 isolate. J Virol 77: 11244-11259.
-
(2003)
J Virol
, vol.77
, pp. 11244-11259
-
-
Srivastava, I.K.1
Stamatatos, L.2
Kan, E.3
Vajdy, M.4
Lian, Y.5
-
45
-
-
21644446614
-
The V1, V2, and V3 regions of the human immunodeficiency virus type 1 envelope differentially affect the viral phenotype in an isolate-dependent manner
-
Saunders CJ, McCaffrey RA, Zharkikh I, Kraft Z, Malenbaum SE, et al. (2005) The V1, V2, and V3 regions of the human immunodeficiency virus type 1 envelope differentially affect the viral phenotype in an isolate-dependent manner. J Virol 79: 9069-9080.
-
(2005)
J Virol
, vol.79
, pp. 9069-9080
-
-
Saunders, C.J.1
McCaffrey, R.A.2
Zharkikh, I.3
Kraft, Z.4
Malenbaum, S.E.5
-
46
-
-
0035925592
-
Mucosal vaccines: non toxic derivatives of LT and CT as mucosal adjuvants
-
Pizza M, Giuliani MM, Fontana MR, Monaci E, Douce G, et al. (2001) Mucosal vaccines: non toxic derivatives of LT and CT as mucosal adjuvants. Vaccine 19: 2534-2541.
-
(2001)
Vaccine
, vol.19
, pp. 2534-2541
-
-
Pizza, M.1
Giuliani, M.M.2
Fontana, M.R.3
Monaci, E.4
Douce, G.5
-
47
-
-
33749650756
-
Innate anti-viral immunity is associated with the protection elicited by the simian immunodeficiency virus (SIV) live attenuated virus vaccine in cynomolgus monkeys
-
Goletti D, Macchia I, Leone P, Pace M, Sernicola L, et al. (2006) Innate anti-viral immunity is associated with the protection elicited by the simian immunodeficiency virus (SIV) live attenuated virus vaccine in cynomolgus monkeys. Med Sci Monit 12: BR330-340.
-
(2006)
Med Sci Monit
, vol.12
-
-
Goletti, D.1
Macchia, I.2
Leone, P.3
Pace, M.4
Sernicola, L.5
-
48
-
-
4444238182
-
Use of retroviral vectors for the analysis of SIV/HIV-specific CD8 T cell responses
-
Negri RM, Buffa V, Leone P, Bona R, Borghi M, et al. (2004) Use of retroviral vectors for the analysis of SIV/HIV-specific CD8 T cell responses. J Immunol Methods 291: 153-163.
-
(2004)
J Immunol Methods
, vol.291
, pp. 153-163
-
-
Negri, R.M.1
Buffa, V.2
Leone, P.3
Bona, R.4
Borghi, M.5
-
49
-
-
10744229841
-
Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells
-
Yu X, Zhan X, D'Costa J, Tanavde VM, Ye Z, et al. (2003) Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Mol Ther 7: 827-838.
-
(2003)
Mol Ther
, vol.7
, pp. 827-838
-
-
Yu, X.1
Zhan, X.2
D'Costa, J.3
Tanavde, V.M.4
Ye, Z.5
-
50
-
-
0031686754
-
High-titer human immunodeficiency virus type 1-based vector systems for gene delivery into nondividing cells
-
Mochizuki H, Schwartz JP, Tanaka K, Brady RO, Reiser J, (1998) High-titer human immunodeficiency virus type 1-based vector systems for gene delivery into nondividing cells. J Virol 72: 8873-8883.
-
(1998)
J Virol
, vol.72
, pp. 8873-8883
-
-
Mochizuki, H.1
Schwartz, J.P.2
Tanaka, K.3
Brady, R.O.4
Reiser, J.5
-
51
-
-
0023638246
-
Recovery of HIV-related retroviruses from Italian patients with AIDS or AIDS-related complex and from asymptomatic at-risk individuals
-
Rossi GB, Verani P, Macchi B, Federico M, Orecchia A, et al. (1987) Recovery of HIV-related retroviruses from Italian patients with AIDS or AIDS-related complex and from asymptomatic at-risk individuals. Ann N Y Acad Sci 511: 390-400.
-
(1987)
Ann N Y Acad Sci
, vol.511
, pp. 390-400
-
-
Rossi, G.B.1
Verani, P.2
Macchi, B.3
Federico, M.4
Orecchia, A.5
-
52
-
-
0031661154
-
Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strains
-
Huang L, Bosch I, Hofmann W, Sodroski J, Pardee AB, (1998) Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strains. J Virol 72: 8952-8960.
-
(1998)
J Virol
, vol.72
, pp. 8952-8960
-
-
Huang, L.1
Bosch, I.2
Hofmann, W.3
Sodroski, J.4
Pardee, A.B.5
-
53
-
-
33846585525
-
Generation and characterization of a stable cell population releasing fluorescent HIV-1-based Virus Like Particles in an inducible way
-
Muratori C, D'Aloja P, Superti F, Tinari A, Sol-Foulon N, et al. (2006) Generation and characterization of a stable cell population releasing fluorescent HIV-1-based Virus Like Particles in an inducible way. BMC. Biotechnol 6: 52.
-
(2006)
BMC. Biotechnol
, vol.6
, pp. 52
-
-
Muratori, C.1
D'Aloja, P.2
Superti, F.3
Tinari, A.4
Sol-Foulon, N.5
-
54
-
-
0027136282
-
Comparative protein modelling by satisfaction of spatial restraints
-
Sali A, Blundell TL, (1993) Comparative protein modelling by satisfaction of spatial restraints. J Mol Biol 234: 779-815.
-
(1993)
J Mol Biol
, vol.234
, pp. 779-815
-
-
Sali, A.1
Blundell, T.L.2
-
55
-
-
23444454552
-
The Amber biomolecular simulation programs
-
Case DA, Cheatham TE 3rd, Darden T, Gohlke H, Luo R, et al (2005) The Amber biomolecular simulation programs. J Comput Chem 26: 1668-1688.
-
(2005)
J Comput Chem
, vol.26
, pp. 1668-1688
-
-
Case, D.A.1
Cheatham 3rd, T.E.2
Darden, T.3
Gohlke, H.4
Luo, R.5
-
56
-
-
0033623587
-
1H-13C nuclear magnetic resonance assignment and structural characterization of HIV-1 Tat protein
-
Péloponèse JM Jr, Grégoire C, Opi S, Esquieu D, Sturgis J, et al. (2000) 1H-13C nuclear magnetic resonance assignment and structural characterization of HIV-1 Tat protein. C R Acad Sci III 323: 883-94.
-
(2000)
C R Acad Sci III
, vol.323
, pp. 883-894
-
-
Péloponèse Jr., J.M.1
Grégoire, C.2
Opi, S.3
Esquieu, D.4
Sturgis, J.5
-
57
-
-
0034765711
-
Homonuclear (1)H-NMR assignment and structural characterization of human immunodeficiency virus type 1 Tat Mal protein
-
Grégoire C, Péloponèse JM Jr, Esquieu D, Opi S, Campbell G, et al. (2001) Homonuclear (1)H-NMR assignment and structural characterization of human immunodeficiency virus type 1 Tat Mal protein. Biopolymers 62: 324-35.
-
(2001)
Biopolymers
, vol.62
, pp. 324-335
-
-
Grégoire, C.1
Péloponèse Jr., J.M.2
Esquieu, D.3
Opi, S.4
Campbell, G.5
-
58
-
-
13844302894
-
Structure of an unliganded simian immunodeficiency virus gp120 core
-
Chen B, Vogan EM, Gong H, Skehel JJ, Wiley DC, et al. (2005) Structure of an unliganded simian immunodeficiency virus gp120 core. Nature 433: 834-841.
-
(2005)
Nature
, vol.433
, pp. 834-841
-
-
Chen, B.1
Vogan, E.M.2
Gong, H.3
Skehel, J.J.4
Wiley, D.C.5
-
59
-
-
27744597054
-
Structure of a V3-containing HIV-1 gp120 core
-
Huang CC, Tang M, Zhang MY, Majeed S, Montabana E, et al. (2005) Structure of a V3-containing HIV-1 gp120 core. Science 310: 1025-1028.
-
(2005)
Science
, vol.310
, pp. 1025-1028
-
-
Huang, C.C.1
Tang, M.2
Zhang, M.Y.3
Majeed, S.4
Montabana, E.5
-
60
-
-
0034212826
-
BiGGER: a new (soft) docking algorithm for predicting protein interactions
-
Palma PN, Krippahl L, Wampler JE, Moura JJ, (2000) BiGGER: a new (soft) docking algorithm for predicting protein interactions. Proteins 39: 372-384.
-
(2000)
Proteins
, vol.39
, pp. 372-384
-
-
Palma, P.N.1
Krippahl, L.2
Wampler, J.E.3
Moura, J.J.4
-
62
-
-
0037442962
-
HADDOCK: a protein-protein docking approach based on biochemical or biophysical information
-
Dominguez C, Boelens R, Bonvin AM, (2003) HADDOCK: a protein-protein docking approach based on biochemical or biophysical information. J Am Chem Soc 125: 1731-1737.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 1731-1737
-
-
Dominguez, C.1
Boelens, R.2
Bonvin, A.M.3
-
63
-
-
0037023363
-
Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand
-
Xiong JP, Stehle T, Zhang R, Joachimiak A, Frech M, et al. (2002) Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand. Science 296: 151-155.
-
(2002)
Science
, vol.296
, pp. 151-155
-
-
Xiong, J.P.1
Stehle, T.2
Zhang, R.3
Joachimiak, A.4
Frech, M.5
-
64
-
-
0031710033
-
A third-generation lentivirus vector with a conditional packaging system
-
Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, et al. (1998) A third-generation lentivirus vector with a conditional packaging system. J Virol 72(11): 8463-71.
-
(1998)
J Virol
, vol.72
, Issue.11
, pp. 8463-8471
-
-
Dull, T.1
Zufferey, R.2
Kelly, M.3
Mandel, R.J.4
Nguyen, M.5
-
65
-
-
0031058001
-
Human blood dendritic cells: binding to vascular endothelium and expression of adhesion molecules
-
Brown KA, Bedford P, Macey M, McCarthy DA, Leroy F, et al. (1997) Human blood dendritic cells: binding to vascular endothelium and expression of adhesion molecules. Clin Exp Immunol 107: 601-607.
-
(1997)
Clin Exp Immunol
, vol.107
, pp. 601-607
-
-
Brown, K.A.1
Bedford, P.2
Macey, M.3
McCarthy, D.A.4
Leroy, F.5
-
66
-
-
0032510194
-
Monocyte-derived dendritic cells and monocytes migrate to HIV-Tat RGD and basic peptides
-
Benelli R, Mortarini R, Anichini A, Giunciuglio D, Noonan DM, et al. (1998) Monocyte-derived dendritic cells and monocytes migrate to HIV-Tat RGD and basic peptides. AIDS 12: 261-268.
-
(1998)
AIDS
, vol.12
, pp. 261-268
-
-
Benelli, R.1
Mortarini, R.2
Anichini, A.3
Giunciuglio, D.4
Noonan, D.M.5
-
67
-
-
0033939342
-
Comparative analysis of integrin expression on monocyte-derived macrophages and monocyte-derived dendritic cells
-
Ammon C, Meyer SP, Schwarzfischer L, Krause SW, Andreesen R, et al. (2000) Comparative analysis of integrin expression on monocyte-derived macrophages and monocyte-derived dendritic cells. Immunology 100: 364-369.
-
(2000)
Immunology
, vol.100
, pp. 364-369
-
-
Ammon, C.1
Meyer, S.P.2
Schwarzfischer, L.3
Krause, S.W.4
Andreesen, R.5
-
68
-
-
0034667982
-
Maturation-dependent expression and function of the CD49d integrin on monocyte-derived human dendritic cells
-
Puig-Kröger A, Sanz-Rodríguez F, Longo N, Sánchez-Mateos P, Botella L, et al. (2000) Maturation-dependent expression and function of the CD49d integrin on monocyte-derived human dendritic cells. J Immunol 165: 4338-4345.
-
(2000)
J Immunol
, vol.165
, pp. 4338-4345
-
-
Puig-Kröger, A.1
Sanz-Rodríguez, F.2
Longo, N.3
Sánchez-Mateos, P.4
Botella, L.5
-
69
-
-
0035070929
-
Efficient gene transduction by RGD-fiber modified recombinant adenovirus into dendritic cells
-
Sada-Mikami R, Heike Y, Kanai S, Azuma M, Shirakawa K, et al. (2001) Efficient gene transduction by RGD-fiber modified recombinant adenovirus into dendritic cells. Jpn J Cancer Res 92: 321-327.
-
(2001)
Jpn J Cancer Res
, vol.92
, pp. 321-327
-
-
Sada-Mikami, R.1
Heike, Y.2
Kanai, S.3
Azuma, M.4
Shirakawa, K.5
-
71
-
-
77955280992
-
The modulation of dendritic cell integrin binding and activation by RGD-peptide density gradient substrates
-
Acharya AP, (2010) The modulation of dendritic cell integrin binding and activation by RGD-peptide density gradient substrates. Biomaterials 31: 7444-7454.
-
(2010)
Biomaterials
, vol.31
, pp. 7444-7454
-
-
Acharya, A.P.1
-
72
-
-
30044447736
-
Immune cell migration in inflammation: present and future therapeutic targets
-
Luster AD, Alon R, von Andrian UH, (2005) Immune cell migration in inflammation: present and future therapeutic targets. Nat Immunol 6: 1182-1190.
-
(2005)
Nat Immunol
, vol.6
, pp. 1182-1190
-
-
Luster, A.D.1
Alon, R.2
von Andrian, U.H.3
-
73
-
-
77949409948
-
Targeting early infection to prevent HIV-1 mucosal transmission
-
Haase AT, (2010) Targeting early infection to prevent HIV-1 mucosal transmission. Nature 11: 217-223.
-
(2010)
Nature
, vol.11
, pp. 217-223
-
-
Haase, A.T.1
-
74
-
-
20144389037
-
Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope protein
-
Marchiò S, Alfano M, Primo L, Gramaglia D, Butini L, et al. (2005) Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope protein. Blood 105: 2802-2811.
-
(2005)
Blood
, vol.105
, pp. 2802-2811
-
-
Marchiò, S.1
Alfano, M.2
Primo, L.3
Gramaglia, D.4
Butini, L.5
-
75
-
-
18144397438
-
Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic subtypes and may impact viral RNA levels
-
Chohan B, Lang D, Sagar M, Korber B, Lavreys L, et al. (2005) Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic subtypes and may impact viral RNA levels. J Virol 79: 6528-6531.
-
(2005)
J Virol
, vol.79
, pp. 6528-6531
-
-
Chohan, B.1
Lang, D.2
Sagar, M.3
Korber, B.4
Lavreys, L.5
-
76
-
-
12144289425
-
Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission
-
Derdeyn CA, Decker JM, Bibollet-Ruche F, Mokili JL, Muldoon M, et al. (2004) Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission. Science 303: 2019-2022.
-
(2004)
Science
, vol.303
, pp. 2019-2022
-
-
Derdeyn, C.A.1
Decker, J.M.2
Bibollet-Ruche, F.3
Mokili, J.L.4
Muldoon, M.5
-
77
-
-
33846552274
-
Role of V1V2 and other human immunodeficiency virus type 1 envelope domains in resistance to autologous neutralization during clade C infection
-
Rong R, Bibollet-Ruche F, Mulenga J, Allen S, Blackwell JL, et al. (2007) Role of V1V2 and other human immunodeficiency virus type 1 envelope domains in resistance to autologous neutralization during clade C infection. J Virol 81: 1350-1359.
-
(2007)
J Virol
, vol.81
, pp. 1350-1359
-
-
Rong, R.1
Bibollet-Ruche, F.2
Mulenga, J.3
Allen, S.4
Blackwell, J.L.5
-
78
-
-
33748925430
-
Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity
-
Sagar M, Wu X, Lee S, Overbaugh J, (2006) Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity. J Virol 80: 9586-9598.
-
(2006)
J Virol
, vol.80
, pp. 9586-9598
-
-
Sagar, M.1
Wu, X.2
Lee, S.3
Overbaugh, J.4
-
79
-
-
0035000679
-
The ability of an oligomeric human immunodeficiency virus type 1 (HIV-1) envelope antigen to elicit neutralizing antibodies against primary HIV-1 isolates is improved following partial deletion of the second hypervariable region
-
Barnett SW, Lu S, Srivastava I, Cherpelis S, Gettie A, et al. (2001) The ability of an oligomeric human immunodeficiency virus type 1 (HIV-1) envelope antigen to elicit neutralizing antibodies against primary HIV-1 isolates is improved following partial deletion of the second hypervariable region. J Virol 75: 5526-5540.
-
(2001)
J Virol
, vol.75
, pp. 5526-5540
-
-
Barnett, S.W.1
Lu, S.2
Srivastava, I.3
Cherpelis, S.4
Gettie, A.5
-
80
-
-
0030812563
-
Replication and neutralization of human immunodeficiency virus type 1 lacking the V1 and V2 variable loops of the gp120 envelope glycoprotein
-
Cao J, Sullivan N, Desjardin E, Parolin C, Robinson J, et al. (1997) Replication and neutralization of human immunodeficiency virus type 1 lacking the V1 and V2 variable loops of the gp120 envelope glycoprotein. J Virol 71: 9808-9812.
-
(1997)
J Virol
, vol.71
, pp. 9808-9812
-
-
Cao, J.1
Sullivan, N.2
Desjardin, E.3
Parolin, C.4
Robinson, J.5
-
81
-
-
0032169683
-
Effect of major deletions in the V1 and V2 loops of a macrophage-tropic HIV type 1 isolate on viral envelope structure, cell entry, and replication
-
Stamatatos L, Wiskerchen M, Cheng-Mayer C, (1998) Effect of major deletions in the V1 and V2 loops of a macrophage-tropic HIV type 1 isolate on viral envelope structure, cell entry, and replication. AIDS Res Hum Retroviruses 14: 1129-1139.
-
(1998)
AIDS Res Hum Retroviruses
, vol.14
, pp. 1129-1139
-
-
Stamatatos, L.1
Wiskerchen, M.2
Cheng-Mayer, C.3
-
82
-
-
0029119783
-
Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding
-
Wyatt R, Moore J, Accola M, Desjardin E, Robinson J, et al. (1995) Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding. J Virol 69: 5723-5733.
-
(1995)
J Virol
, vol.69
, pp. 5723-5733
-
-
Wyatt, R.1
Moore, J.2
Accola, M.3
Desjardin, E.4
Robinson, J.5
-
83
-
-
33751256549
-
Candidate HIV-1 Tat vaccine development: from basic science to clinical trials
-
Ensoli B, Fiorelli V, Ensoli F, Cafaro A, Titti F, et al. (2006) Candidate HIV-1 Tat vaccine development: from basic science to clinical trials. AIDS 20: 2245-2261.
-
(2006)
AIDS
, vol.20
, pp. 2245-2261
-
-
Ensoli, B.1
Fiorelli, V.2
Ensoli, F.3
Cafaro, A.4
Titti, F.5
|