메뉴 건너뛰기




Volumn 29, Issue 8, 2010, Pages 1348-1362

Phosphatidylinositol-(4,5)-bisphosphate enables efficient secretion of HIV-1 Tat by infected T-cells

Author keywords

HIV 1; PIP2; Tat; Toxin; Unconventional secretion

Indexed keywords

PHOSPHATIDYLINOSITOL (4,5) BISPHOSPHATE; PHOSPHOLIPID; TRANSACTIVATOR PROTEIN; TRYPTOPHAN; UNCLASSIFIED DRUG;

EID: 77951498245     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2010.32     Document Type: Article
Times cited : (150)

References (62)
  • 1
    • 0034631854 scopus 로고    scopus 로고
    • Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate
    • Aharonovitz O, Zaun HC, Balla T, York JD, Orlowski J, Grinstein S (2000) Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate. J Cell Biol 150: 213-224
    • (2000) J Cell Biol , vol.150 , pp. 213-224
    • Aharonovitz, O.1    Zaun, H.C.2    Balla, T.3    York, J.D.4    Orlowski, J.5    Grinstein, S.6
  • 2
    • 0035451761 scopus 로고    scopus 로고
    • PI 3-K and T-cell activation: Limitations of T-leukemic cell lines as signaling models
    • Astoul E, Edmunds C, Cantrell DA, Ward SG (2001) PI 3-K and T-cell activation: limitations of T-leukemic cell lines as signaling models. Trends Immunol 22: 490-496
    • (2001) Trends Immunol , vol.22 , pp. 490-496
    • Astoul, E.1    Edmunds, C.2    Cantrell, D.A.3    Ward, S.G.4
  • 3
    • 0034722326 scopus 로고    scopus 로고
    • Mutagenesis of the phosphatidylinositol 4,5-bisphosphate (PIP(2)) binding site in the NH(2)-terminal domain of ezrin correlates with its altered cellular distribution
    • Barret C, Roy C, Montcourrier P, Mangeat P, Niggli V (2000) Mutagenesis of the phosphatidylinositol 4,5-bisphosphate (PIP(2)) binding site in the NH(2)-terminal domain of ezrin correlates with its altered cellular distribution. J Cell Biol 151: 1067-1080
    • (2000) J Cell Biol , vol.151 , pp. 1067-1080
    • Barret, C.1    Roy, C.2    Montcourrier, P.3    Mangeat, P.4    Niggli, V.5
  • 5
    • 38549106998 scopus 로고    scopus 로고
    • Quantitative analysis of the binding of ezrin to large unilamellar vesicles containing phosphatidylinositol(4,5)-bisphosphate
    • Blin G, Margeat E, Carvalho K, Royer CA, Roy C, Picart C (2008) Quantitative analysis of the binding of ezrin to large unilamellar vesicles containing phosphatidylinositol(4,5)-bisphosphate. Biophys J 94: 1021-1033
    • (2008) Biophys J , vol.94 , pp. 1021-1033
    • Blin, G.1    Margeat, E.2    Carvalho, K.3    Royer, C.A.4    Roy, C.5    Picart, C.6
  • 7
    • 0035802108 scopus 로고    scopus 로고
    • Phosphatidylinositol 4,5-bisphosphate and Arf6-regulated membrane traffic
    • Brown FD, Rozelle AL, Yin HL, Balla T, Donaldson JG (2001) Phosphatidylinositol 4,5-bisphosphate and Arf6-regulated membrane traffic. J Cell Biol 154: 1007-1017
    • (2001) J Cell Biol , vol.154 , pp. 1007-1017
    • Brown, F.D.1    Rozelle, A.L.2    Yin, H.L.3    Balla, T.4    Donaldson, J.G.5
  • 8
    • 0037465698 scopus 로고    scopus 로고
    • Using a novel dual fluorescence quenching assay for measurement of tryptophan depth within lipid bilayers to determine hydrophobic alpha-helix locations within membranes
    • Caputo GA, London E (2003) Using a novel dual fluorescence quenching assay for measurement of tryptophan depth within lipid bilayers to determine hydrophobic alpha-helix locations within membranes. Biochemistry 42: 3265-3274
    • (2003) Biochemistry , vol.42 , pp. 3265-3274
    • Caputo, G.A.1    London, E.2
  • 9
    • 55549118226 scopus 로고    scopus 로고
    • Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides
    • Chan R, Uchil PD, Jin J, Shui G, Ott DE, Mothes W, Wenk MR (2008) Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides. J Virol 82: 11228-11238
    • (2008) J Virol , vol.82 , pp. 11228-11238
    • Chan, R.1    Uchil, P.D.2    Jin, J.3    Shui, G.4    Ott, D.E.5    Mothes, W.6    Wenk, M.R.7
  • 10
    • 0030862924 scopus 로고    scopus 로고
    • HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region
    • Chang HC, Samaniego F, Nair BC, Buonaguro L, Ensoli B (1997) HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region. AIDS 11:1421-1431
    • (1997) AIDS , vol.11 , pp. 1421-1431
    • Chang, H.C.1    Samaniego, F.2    Nair, B.C.3    Buonaguro, L.4    Ensoli, B.5
  • 13
    • 11144292734 scopus 로고    scopus 로고
    • GRP1 pleckstrin homology domain: Activation parameters and novel search mechanism for rare target lipid
    • Corbin JA, Dirkx RA, Falke JJ (2004) GRP1 pleckstrin homology domain: activation parameters and novel search mechanism for rare target lipid. Biochemistry 43: 16161-16173
    • (2004) Biochemistry , vol.43 , pp. 16161-16173
    • Corbin, J.A.1    Dirkx, R.A.2    Falke, J.J.3
  • 14
  • 15
    • 33749836234 scopus 로고    scopus 로고
    • Phosphoinositides in cell regulation and membrane dynamics
    • Di Paolo G, De Camilli P (2006) Phosphoinositides in cell regulation and membrane dynamics. Nature 443: 651-657
    • (2006) Nature , vol.443 , pp. 651-657
    • Di Paolo, G.1    De Camilli, P.2
  • 16
    • 34247872880 scopus 로고    scopus 로고
    • Identification of a signal peptide for unconventional secretion
    • Dupont E, Prochiantz A, Joliot A (2007) Identification of a signal peptide for unconventional secretion. J Biol Chem 282: 8994-9000
    • (2007) J Biol Chem , vol.282 , pp. 8994-9000
    • Dupont, E.1    Prochiantz, A.2    Joliot, A.3
  • 17
    • 0025344596 scopus 로고
    • Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients
    • Ensoli B, Barillari G, Salahuddin SZ, Gallo RC, Wong-Staal F (1990) Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients. Nature 345: 84-86
    • (1990) Nature , vol.345 , pp. 84-86
    • Ensoli, B.1    Barillari, G.2    Salahuddin, S.Z.3    Gallo, R.C.4    Wong-Staal, F.5
  • 18
    • 0027458469 scopus 로고
    • Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation
    • Ensoli B, Buonaguro L, Barillari G, Fiorelli V, Gendelman R, Morgan RA, Wingfield P, Gallo RC (1993) Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J Virol 67: 277-287
    • (1993) J Virol , vol.67 , pp. 277-287
    • Ensoli, B.1    Buonaguro, L.2    Barillari, G.3    Fiorelli, V.4    Gendelman, R.5    Morgan, R.A.6    Wingfield, P.7    Gallo, R.C.8
  • 19
    • 0033587718 scopus 로고    scopus 로고
    • Tat as one key to HIV-induced immune pathogen-esis and Tat toxoid as an important component of a vaccine
    • Gallo RC (1999) Tat as one key to HIV-induced immune pathogen-esis and Tat toxoid as an important component of a vaccine. Proc Natl Acad Sci USA 96: 8324-8326
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 8324-8326
    • Gallo, R.C.1
  • 21
    • 0025815391 scopus 로고
    • Transcellular transactivation by the human immunodeficiency virus type 1 tat protein
    • Helland DE, Welles JL, Caputo A, Haseltine WA (1991) Transcellular transactivation by the human immunodeficiency virus type 1 tat protein. J Virol 65: 4547-4549
    • (1991) J Virol , vol.65 , pp. 4547-4549
    • Helland, D.E.1    Welles, J.L.2    Caputo, A.3    Haseltine, W.A.4
  • 22
    • 33845313646 scopus 로고    scopus 로고
    • PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane
    • Heo WD, Inoue T, Park WS, Kim ML, Park BO, Wandless TJ, Meyer T (2006) PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane. Science 314: 1458-1461
    • (2006) Science , vol.314 , pp. 1458-1461
    • Heo, W.D.1    Inoue, T.2    Park, W.S.3    Kim, M.L.4    Park, B.O.5    Wandless, T.J.6    Meyer, T.7
  • 23
    • 0034625410 scopus 로고    scopus 로고
    • A pleckstrin homology domain specific for phosphatidylinositol 4, 5-bispho-sphate (PtdIns-4,5-P2) and fused to green fluorescent protein identifies plasma membrane PtdIns-4,5-P2 as being important in exocytosis
    • Holz RW, Hlubek MD, Sorensen SD, Fisher SK, Balla T, Ozaki S, Prestwich GD, Stuenkel EL, Bittner MA (2000) A pleckstrin homology domain specific for phosphatidylinositol 4, 5-bispho-sphate (PtdIns-4,5-P2) and fused to green fluorescent protein identifies plasma membrane PtdIns-4,5-P2 as being important in exocytosis. J Biol Chem 275: 17878-17885
    • (2000) J Biol Chem , vol.275 , pp. 17878-17885
    • Holz, R.W.1    Hlubek, M.D.2    Sorensen, S.D.3    Fisher, S.K.4    Balla, T.5    Ozaki, S.6    Prestwich, G.D.7    Stuenkel, E.L.8    Bittner, M.A.9
  • 25
    • 0031661154 scopus 로고    scopus 로고
    • Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strains
    • Huang L, Bosch I, Hofmann W, Sodroski J, Pardee AB (1998) Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strains. J Virol 72: 8952-8960
    • (1998) J Virol , vol.72 , pp. 8952-8960
    • Huang, L.1    Bosch, I.2    Hofmann, W.3    Sodroski, J.4    Pardee, A.B.5
  • 26
    • 1242269845 scopus 로고    scopus 로고
    • Multiple effects of HIV-1 trans-activator protein on the pathogenesis of HIV-1 infection
    • Huigen MC, Kamp W, Nottet HS (2004) Multiple effects of HIV-1 trans-activator protein on the pathogenesis of HIV-1 infection. Eur J Clin Invest 34: 57-66
    • (2004) Eur J Clin Invest , vol.34 , pp. 57-66
    • Huigen, M.C.1    Kamp, W.2    Nottet, H.S.3
  • 27
    • 0032855497 scopus 로고    scopus 로고
    • Multifaceted activities of the HIV-1 transactivator of transcription, Tat
    • Jeang KT, Xiao H, Rich EA (1999) Multifaceted activities of the HIV-1 transactivator of transcription, Tat. J Biol Chem 274: 28837-28840
    • (1999) J Biol Chem , vol.274 , pp. 28837-28840
    • Jeang, K.T.1    Xiao, H.2    Rich, E.A.3
  • 28
    • 1542609485 scopus 로고    scopus 로고
    • Transduction peptides: From technology to physiology
    • Joliot A, Prochiantz A (2004) Transduction peptides: from technology to physiology. Nat Cell Biol 6: 189-196
    • (2004) Nat Cell Biol , vol.6 , pp. 189-196
    • Joliot, A.1    Prochiantz, A.2
  • 29
    • 0032585530 scopus 로고    scopus 로고
    • Phosphatidylinositol-4,5-bisphosphate is required for endocytic coated vesicle formation
    • Jost M, Simpson F, Kavran JM, Lemmon MA, Schmid SL (1998) Phosphatidylinositol-4,5-bisphosphate is required for endocytic coated vesicle formation. Curr Biol 8: 1399-1402
    • (1998) Curr Biol , vol.8 , pp. 1399-1402
    • Jost, M.1    Simpson, F.2    Kavran, J.M.3    Lemmon, M.A.4    Schmid, S.L.5
  • 30
    • 39749084641 scopus 로고    scopus 로고
    • Active caspase-1 is a regulator of unconventional protein secretion
    • Keller M, Ruegg A, Werner S, Beer HD (2008) Active caspase-1 is a regulator of unconventional protein secretion. Cell 132: 818-831
    • (2008) Cell , vol.132 , pp. 818-831
    • Keller, M.1    Ruegg, A.2    Werner, S.3    Beer, H.D.4
  • 31
    • 0038281249 scopus 로고    scopus 로고
    • Phosphoinositide recognition domains
    • Lemmon MA (2003) Phosphoinositide recognition domains. Traffic 4: 201-213
    • (2003) Traffic , vol.4 , pp. 201-213
    • Lemmon, M.A.1
  • 32
    • 0028874438 scopus 로고
    • Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain
    • Lemmon MA, Ferguson KM, O'Brien R, Sigler PB, Schlessinger J (1995) Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain. Proc Natl Acad Sci USA 92: 10472-10476
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 10472-10476
    • Lemmon, M.A.1    Ferguson, K.M.2    O'Brien, R.3    Sigler, P.B.4    Schlessinger, J.5
  • 33
    • 0028190349 scopus 로고
    • Spatial association of HIV-1 tat protein and the nucleolar transport protein B23 in stably transfected Jurkat T-cells
    • Marasco WA, Szilvay AM, Kalland KH, Helland DG, Reyes HM, Walter RJ (1994) Spatial association of HIV-1 tat protein and the nucleolar transport protein B23 in stably transfected Jurkat T-cells. Arch Virol 139: 133-154
    • (1994) Arch Virol , vol.139 , pp. 133-154
    • Marasco, W.A.1    Szilvay, A.M.2    Kalland, K.H.3    Helland, D.G.4    Reyes, H.M.5    Walter, R.J.6
  • 34
    • 0035914391 scopus 로고    scopus 로고
    • Visualization of in vivo direct interaction between HIV-1 TAT and human cyclin T1 in specific subcellular compartments by fluorescence resonance energy transfer
    • Marcello A, Cinelli RA, Ferrari A, Signorelli A, Tyagi M, Pellegrini V, Beltram F, Giacca M (2001) Visualization of in vivo direct interaction between HIV-1 TAT and human cyclin T1 in specific subcellular compartments by fluorescence resonance energy transfer. J Biol Chem 276: 39220-39225
    • (2001) J Biol Chem , vol.276 , pp. 39220-39225
    • Marcello, A.1    Cinelli, R.A.2    Ferrari, A.3    Signorelli, A.4    Tyagi, M.5    Pellegrini, V.6    Beltram, F.7    Giacca, M.8
  • 35
    • 0026704160 scopus 로고
    • Transcellular activation of the human immunodeficiency virus type 1 long terminal repeat in cocultured lymphocytes
    • Marcuzzi A, Weinberger J, Weinberger OK (1992) Transcellular activation of the human immunodeficiency virus type 1 long terminal repeat in cocultured lymphocytes. J Virol 66: 4228-4232
    • (1992) J Virol , vol.66 , pp. 4228-4232
    • Marcuzzi, A.1    Weinberger, J.2    Weinberger, O.K.3
  • 36
    • 0038708567 scopus 로고    scopus 로고
    • Membrane targeting of Grb2-associated binder-1 (Gab1), scaffolding protein through Src myristoylation sequence substitutes for Gab1 pleckstrin homology domain and switches an epidermal growth factor response to an invasive morphogenic program
    • Maroun CR, Naujokas MA, Park M (2003) Membrane targeting of Grb2-associated binder-1 (Gab1) scaffolding protein through Src myristoylation sequence substitutes for Gab1 pleckstrin homology domain and switches an epidermal growth factor response to an invasive morphogenic program. Mol Biol Cell 14: 1691-1708
    • (2003) Mol Biol Cell , vol.14 , pp. 1691-1708
    • Maroun, C.R.1    Naujokas, M.A.2    Park, M.3
  • 38
    • 20444381680 scopus 로고    scopus 로고
    • Acid-triggered membrane insertion of pseudomonas exotoxin A involves an original mechanism based on pH-regulated trypto-phan exposure
    • Méré J, Morlon-Guyot J, Bonhoure A, Chiche L, Beaumelle B (2005) Acid-triggered membrane insertion of pseudomonas exotoxin A involves an original mechanism based on pH-regulated trypto-phan exposure. J Biol Chem 280: 21194-21201
    • (2005) J Biol Chem , vol.280 , pp. 21194-21201
    • Méré, J.1    Morlon-Guyot, J.2    Bonhoure, A.3    Chiche, L.4    Beaumelle, B.5
  • 39
    • 58849089529 scopus 로고    scopus 로고
    • Mechanisms of regulated unconventional protein secretion
    • Nickel W, Rabouille C (2009) Mechanisms of regulated unconventional protein secretion. Nat Rev Mol Cell Biol 10: 148-155
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 148-155
    • Nickel, W.1    Rabouille, C.2
  • 40
    • 6944255361 scopus 로고    scopus 로고
    • Phosphatidylinositol (4,5) bisphosphate regulates HIV-1 Gag targeting to the plasma membrane
    • Ono A, Ablan SD, Lockett SJ, Nagashima K, Freed EO (2004) Phosphatidylinositol (4,5) bisphosphate regulates HIV-1 Gag targeting to the plasma membrane. Proc Natl Acad Sci USA 101: 14889-14894
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 14889-14894
    • Ono, A.1    Ablan, S.D.2    Lockett, S.J.3    Nagashima, K.4    Freed, E.O.5
  • 41
    • 12944258677 scopus 로고    scopus 로고
    • Comparative analysis of HIV-1 Tat variants
    • Pantano S, Carloni P (2005) Comparative analysis of HIV-1 Tat variants. Proteins 58: 638-643
    • (2005) Proteins , vol.58 , pp. 638-643
    • Pantano, S.1    Carloni, P.2
  • 43
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: Virion clearance rate, infected cell life span, and viral generation time
    • Perelson AS, Neumann AU, Markowitz M, Leonard JM, Ho DD (1996) HIV-1 dynamics in vivo: virion clearance rate, infected cell life span, and viral generation time. Science 271: 1582-1586
    • (1996) Science , vol.271 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 44
    • 0028252718 scopus 로고
    • Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell lines
    • Ranki A, Lagerstedt A, Ovod V, Aavik E, Krohn KJ (1994) Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell lines. Arch Virol 139: 365-378
    • (1994) Arch Virol , vol.139 , pp. 365-378
    • Ranki, A.1    Lagerstedt, A.2    Ovod, V.3    Aavik, E.4    Krohn, K.J.5
  • 47
    • 0042707772 scopus 로고    scopus 로고
    • Contrasting membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domains
    • Stahelin RV, Long F, Peter BJ, Murray D, De Camilli P, McMahon HT, Cho W (2003) Contrasting membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domains. J Biol Chem 278: 28993-28999
    • (2003) J Biol Chem , vol.278 , pp. 28993-28999
    • Stahelin, R.V.1    Long, F.2    Peter, B.J.3    Murray, D.4    De Camilli, P.5    McMahon, H.T.6    Cho, W.7
  • 48
    • 0032488243 scopus 로고    scopus 로고
    • Intracellular trafficking and interactions of the HIV-1 Tat protein
    • Stauber RH, Pavlakis GN (1998) Intracellular trafficking and interactions of the HIV-1 Tat protein. Virology 252: 126-136
    • (1998) Virology , vol.252 , pp. 126-136
    • Stauber, R.H.1    Pavlakis, G.N.2
  • 51
    • 46349098379 scopus 로고    scopus 로고
    • A direct role for phosphatidylinositol-4,5-bisphosphate in unconventional secretion of fibroblast growth factor 2
    • Temmerman K, Ebert AD, Muller HM, Sinning I, Tews I, Nickel W (2008) A direct role for phosphatidylinositol-4,5-bisphosphate in unconventional secretion of fibroblast growth factor 2. Traffic 9: 1204-1217
    • (2008) Traffic , vol.9 , pp. 1204-1217
    • Temmerman, K.1    Ebert, A.D.2    Muller, H.M.3    Sinning, I.4    Tews, I.5    Nickel, W.6
  • 52
    • 0032911885 scopus 로고    scopus 로고
    • The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin beta-dependent nuclear localization signals
    • Truant R, Cullen BR (1999) The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin beta-dependent nuclear localization signals. Mol Cell Biol 19: 1210-1217
    • (1999) Mol Cell Biol , vol.19 , pp. 1210-1217
    • Truant, R.1    Cullen, B.R.2
  • 53
    • 0032547744 scopus 로고    scopus 로고
    • Visualization of phosphoinositides that bind pleckstrin homology domains: Calcium-and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools
    • Varnai P, Balla T (1998) Visualization of phosphoinositides that bind pleckstrin homology domains: calcium-and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools. J Cell Biol 143: 501-510
    • (1998) J Cell Biol , vol.143 , pp. 501-510
    • Varnai, P.1    Balla, T.2
  • 54
    • 2342507144 scopus 로고    scopus 로고
    • HIV-1 Tat enters T-cells using coated pits before translocating from acidified endosomes and eliciting biological responses
    • Vendeville A, Rayne F, Bonhoure A, Bettache N, Montcourrier P, Beaumelle B (2004) HIV-1 Tat enters T-cells using coated pits before translocating from acidified endosomes and eliciting biological responses. Mol Biol Cell 15: 2347-2360
    • (2004) Mol Biol Cell , vol.15 , pp. 2347-2360
    • Vendeville, A.1    Rayne, F.2    Bonhoure, A.3    Bettache, N.4    Montcourrier, P.5    Beaumelle, B.6
  • 55
    • 44049108744 scopus 로고    scopus 로고
    • Toward an AIDS vaccine
    • Walker BD, Burton DR (2008) Toward an AIDS vaccine. Science 320: 760-764
    • (2008) Science , vol.320 , pp. 760-764
    • Walker, B.D.1    Burton, D.R.2
  • 56
    • 0036566427 scopus 로고    scopus 로고
    • Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1
    • Watt SA, Kular G, Fleming IN, Downes CP, Lucocq JM (2002) Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1. Biochem J 363: 657-666
    • (2002) Biochem J , vol.363 , pp. 657-666
    • Watt, S.A.1    Kular, G.2    Fleming, I.N.3    Downes, C.P.4    Lucocq, J.M.5
  • 57
    • 0033198104 scopus 로고    scopus 로고
    • HIV-1 Tat induces monocyte chemoattractant protein-1-mediated monocyte transmigration across a model of the human blood-brain barrier and up-regulates CCR5 expression on human monocytes
    • Weiss JM, Nath A, Major EO, Berman JW (1999) HIV-1 Tat induces monocyte chemoattractant protein-1-mediated monocyte transmigration across a model of the human blood-brain barrier and up-regulates CCR5 expression on human monocytes. J Immunol 163: 2953-2959
    • (1999) J Immunol , vol.163 , pp. 2953-2959
    • Weiss, J.M.1    Nath, A.2    Major, E.O.3    Berman, J.W.4
  • 58
    • 0032987478 scopus 로고    scopus 로고
    • Membrane protein folding and stability: Physical principles
    • White SH, Wimley WC (1999) Membrane protein folding and stability: physical principles. Annu Rev Biophys Biomol Struct 28: 319-365
    • (1999) Annu Rev Biophys Biomol Struct , vol.28 , pp. 319-365
    • White, S.H.1    Wimley, W.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.