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Volumn 23, Issue 11, 2012, Pages 1166-1175

Overexpression of endothelial nitric oxide synthase improves endothelium-dependent vasodilation in arteries infused with helper-dependent adenovirus

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HELPER DEPENDENT ADENOVIRUS VECTOR; MESSENGER RNA; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84869016654     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2012.127     Document Type: Article
Times cited : (6)

References (60)
  • 1
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and the ugly
    • Beckman, J.S., and Koppenol, W.H. (1996). Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and the ugly. Am. J. Physiol. 271, C1424-C1437.
    • (1996) Am. J. Physiol. , vol.271
    • Beckman, J.S.1    Koppenol, W.H.2
  • 2
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman, J.S., Beckman, T.W., Chen, J., et al. (1990). Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. U. S. A. 87, 1620-1624.
    • (1990) Proc. Natl. Acad. Sci. U. S. A. , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3
  • 3
    • 0032480777 scopus 로고    scopus 로고
    • In vivo gene transfer of nitric oxide synthase enhances vasomotor function in carotid arteries from normal and cholesterol-fed rabbits
    • Channon, K.M., Qian, H., Neplioueva, V., et al. (1998a). In vivo gene transfer of nitric oxide synthase enhances vasomotor function in carotid arteries from normal and cholesterol-fed rabbits. Circulation 98, 1905-1911.
    • (1998) Circulation , vol.98 , pp. 1905-1911
    • Channon, K.M.1    Qian, H.2    Neplioueva, V.3
  • 4
    • 0032577967 scopus 로고    scopus 로고
    • Acute host-mediated endothelial injury after adenoviral gene transfer in normal rabbit arteries: Impact on transgene expression and endothelial function
    • Channon, K.M., Qian, H., Youngblood, S.A., et al. (1998b). Acute host-mediated endothelial injury after adenoviral gene transfer in normal rabbit arteries: impact on transgene expression and endothelial function. Circ. Res. 82, 1253-1262.
    • (1998) Circ. Res. , vol.82 , pp. 1253-1262
    • Channon, K.M.1    Qian, H.2    Youngblood, S.A.3
  • 5
    • 0031059375 scopus 로고    scopus 로고
    • Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery
    • Chen, A.F.Y., O'Brien, T., Tsutsui, M., et al. (1997). Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery. Circ. Res. 80, 327-335.
    • (1997) Circ. Res. , vol.80 , pp. 327-335
    • Chen, A.F.Y.1    O'Brien, T.2    Tsutsui, M.3
  • 6
    • 0030426525 scopus 로고    scopus 로고
    • Production and characterization of human 293 cell lines expressing the sitespecific recombinase Cre
    • Chen, L., Anton, M., and Graham, F.L. (1996). Production and characterization of human 293 cell lines expressing the sitespecific recombinase Cre. Somat. Cell Mol. Genet. 22, 477-488.
    • (1996) Somat. Cell Mol. Genet. , vol.22 , pp. 477-488
    • Chen, L.1    Anton, M.2    Graham, F.L.3
  • 7
    • 70350502352 scopus 로고    scopus 로고
    • Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy
    • Chen, Y.H., Chang, M., and Davidson, B.L. (2009). Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy. Nat. Med. 15, 1215-1218.
    • (2009) Nat. Med. , vol.15 , pp. 1215-1218
    • Chen, Y.H.1    Chang, M.2    Davidson, B.L.3
  • 8
    • 0037387579 scopus 로고    scopus 로고
    • Intra-arterial tumor necrosis factor-alpha impairs endothelium-dependent vasodilatation and stimulates local tissue plasminogen activator release in humans
    • Chia, S., Qadan, M., Newton, R., et al. (2003). Intra-arterial tumor necrosis factor-alpha impairs endothelium-dependent vasodilatation and stimulates local tissue plasminogen activator release in humans. Arterioscler. Thromb. Vasc. Biol. 23, 695-701.
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 695-701
    • Chia, S.1    Qadan, M.2    Newton, R.3
  • 9
    • 34249308175 scopus 로고    scopus 로고
    • Molecular engineering of vein bypass grafts
    • Conte, M.S. (2007). Molecular engineering of vein bypass grafts. J. Vasc. Surg. 45(Suppl A), A74-81.
    • (2007) J. Vasc. Surg. , vol.45 , Issue.SUPPL. A
    • Conte, M.S.1
  • 10
    • 79955939666 scopus 로고    scopus 로고
    • Construction of a novel expression cassette for increasing transgene expression in vivo in endothelial cells of large blood vessels
    • Dronadula, N., Du, L., Flynn, R., et al. (2011). Construction of a novel expression cassette for increasing transgene expression in vivo in endothelial cells of large blood vessels. Gene Ther. 18, 501-508.
    • (2011) Gene Ther. , vol.18 , pp. 501-508
    • Dronadula, N.1    Du, L.2    Flynn, R.3
  • 11
    • 79957461678 scopus 로고    scopus 로고
    • Helper-dependent adenoviral vector achieves prolonged, stable expression of IL-10 in rabbit carotid arteries but does not limit early atherogenesis
    • Du, L., Dronadula, N., Tanaka, S., and Dichek, D.A. (2011). Helper-dependent adenoviral vector achieves prolonged, stable expression of IL-10 in rabbit carotid arteries but does not limit early atherogenesis. Hum. Gene Ther. 22, 959-968.
    • (2011) Hum. Gene Ther. , vol.22 , pp. 959-968
    • Du, L.1    Dronadula, N.2    Tanaka, S.3    Dichek, D.A.4
  • 12
    • 0026529017 scopus 로고
    • Low level in vivo gene transfer into the arterial wall through a perforated balloon catheter
    • Flugelman, M.Y., Jaklitsch, M.T., Newman, K.D., et al. (1992). Low level in vivo gene transfer into the arterial wall through a perforated balloon catheter. Circulation 85, 1110-1117.
    • (1992) Circulation , vol.85 , pp. 1110-1117
    • Flugelman, M.Y.1    Jaklitsch, M.T.2    Newman, K.D.3
  • 13
    • 78650875616 scopus 로고    scopus 로고
    • Helper-dependent adenoviral vectors are superior in vitro to first-generation vectors for endothelial cell-targeted gene therapy
    • Flynn, R., Buckler, J.M., Tang, C., et al. (2010). Helper-dependent adenoviral vectors are superior in vitro to first-generation vectors for endothelial cell-targeted gene therapy. Mol. Ther. 18, 2121-2129.
    • (2010) Mol. Ther. , vol.18 , pp. 2121-2129
    • Flynn, R.1    Buckler, J.M.2    Tang, C.3
  • 14
    • 80053571267 scopus 로고    scopus 로고
    • Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosis
    • Flynn, R., Qian, K., Tang, C., et al. (2011). Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosis. Mol. Ther. 19, 1833-1841.
    • (2011) Mol. Ther. , vol.19 , pp. 1833-1841
    • Flynn, R.1    Qian, K.2    Tang, C.3
  • 15
    • 0030577061 scopus 로고    scopus 로고
    • The 1996 Albert Lasker Medical Research Awards. The discovery of endothelium-derived relaxing factor and its importance in the identification of nitric oxide
    • Furchgott, R.F. (1996). The 1996 Albert Lasker Medical Research Awards. The discovery of endothelium-derived relaxing factor and its importance in the identification of nitric oxide. JAMA 276, 1186-1188.
    • (1996) JAMA , vol.276 , pp. 1186-1188
    • Furchgott, R.F.1
  • 16
    • 34948856860 scopus 로고    scopus 로고
    • Cardiovascular gene therapy: Current status and therapeutic potential
    • Gaffney, M.M., Hynes, S.O., Barry, F., and O'Brien, T. (2007). Cardiovascular gene therapy: current status and therapeutic potential. Br. J. Pharmacol. 152, 175-188.
    • (2007) Br. J. Pharmacol. , vol.152 , pp. 175-188
    • Gaffney, M.M.1    Hynes, S.O.2    Barry, F.3    O'Brien, T.4
  • 17
    • 12344255581 scopus 로고    scopus 로고
    • Gene transfer into rabbit arteries with adeno-associated virus and adenovirus vectors
    • Gruchala, M., Bhardwaj, S., Pajusola, K., et al. (2004). Gene transfer into rabbit arteries with adeno-associated virus and adenovirus vectors. J. Gene Med. 6, 545-554.
    • (2004) J. Gene Med. , vol.6 , pp. 545-554
    • Gruchala, M.1    Bhardwaj, S.2    Pajusola, K.3
  • 18
    • 9144251963 scopus 로고    scopus 로고
    • Gene transfer of endothelial NO synthase, but not eNOS plus inducible NOS, regressed atherosclerosis in rabbits
    • Hayashi, T., Sumi, D., Juliet, P.A., et al. (2004). Gene transfer of endothelial NO synthase, but not eNOS plus inducible NOS, regressed atherosclerosis in rabbits. Cardiovasc. Res. 61, 339-351.
    • (2004) Cardiovasc. Res. , vol.61 , pp. 339-351
    • Hayashi, T.1    Sumi, D.2    Juliet, P.A.3
  • 19
    • 0001957609 scopus 로고
    • Adenoviridae and their replication
    • B.N. Fields and D.M. Knipe, eds. (Raven Press, New York)
    • Horwitz, M.S. (1991). Adenoviridae and their replication. In Fundamental Virology. B.N. Fields and D.M. Knipe, eds. (Raven Press, New York) pp. 771-813.
    • (1991) Fundamental Virology , pp. 771-813
    • Horwitz, M.S.1
  • 20
    • 79957497629 scopus 로고    scopus 로고
    • Helper-dependent adenovirus is superior to first-generation adenovirus for expressing transgenes in atherosclerosis-prone arteries
    • Jiang, B., Qian, K., Du, L., et al. (2011). Helper-dependent adenovirus is superior to first-generation adenovirus for expressing transgenes in atherosclerosis-prone arteries. Arterioscler. Thromb. Vasc. Biol. 31, 1317-1325.
    • (2011) Arterioscler. Thromb. Vasc. Biol. , vol.31 , pp. 1317-1325
    • Jiang, B.1    Qian, K.2    Du, L.3
  • 21
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • Kubes, P., Suzuki, M., and Granger, D.N. (1991). Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc. Natl. Acad. Sci. U. S. A. 88, 4651-4655.
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 4651-4655
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 22
    • 0030754269 scopus 로고    scopus 로고
    • Enhanced endothelium-dependent relaxations after gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries
    • Kullo, I.J., Mozes, G., Schwartz, R.S., et al. (1997). Enhanced endothelium-dependent relaxations after gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries. Hypertension 30, 314-320.
    • (1997) Hypertension , vol.30 , pp. 314-320
    • Kullo, I.J.1    Mozes, G.2    Schwartz, R.S.3
  • 23
    • 0030742242 scopus 로고    scopus 로고
    • Vasomotor dysfunction early after exposure of normal rabbit arteries to an adenoviral vector
    • Lafont, A., Loirand, G., Pacaud, P., et al. (1997). Vasomotor dysfunction early after exposure of normal rabbit arteries to an adenoviral vector. Hum. Gene Ther. 8, 1033-1040.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 1033-1040
    • Lafont, A.1    Loirand, G.2    Pacaud, P.3
  • 24
    • 0027407198 scopus 로고
    • In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors
    • Lemarchand, P., Jones, M., Yamada, I., and Crystal, R.G. (1993). In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors. Circ. Res. 72, 1132-1138.
    • (1993) Circ. Res. , vol.72 , pp. 1132-1138
    • Lemarchand, P.1    Jones, M.2    Yamada, I.3    Crystal, R.G.4
  • 25
    • 72949102434 scopus 로고    scopus 로고
    • Genetic manipulation of endothelial cells by viral vectors
    • Lindemann, D., and Schnittler, H. (2009). Genetic manipulation of endothelial cells by viral vectors. Thromb. Haemost. 102, 1135-1143.
    • (2009) Thromb. Haemost. , vol.102 , pp. 1135-1143
    • Lindemann, D.1    Schnittler, H.2
  • 26
    • 70449581253 scopus 로고    scopus 로고
    • Constriction of arteries by urokinase-type plasminogen activator requires catalytic activity and is independent of NH2-terminal domains
    • Massey, P.G., Tanaka, S., Buckler, J., et al. (2009). Constriction of arteries by urokinase-type plasminogen activator requires catalytic activity and is independent of NH2-terminal domains. Thromb. Haemost. 102, 983-992.
    • (2009) Thromb. Haemost. , vol.102 , pp. 983-992
    • Massey, P.G.1    Tanaka, S.2    Buckler, J.3
  • 27
    • 0027942628 scopus 로고
    • Treatment of intracoronary thrombus with local urokinase infusion using a new, site-specific drug delivery system: The Dispatch catheter
    • McKay, R.G., Fram, D.B., Hirst, J.A., et al. (1994). Treatment of intracoronary thrombus with local urokinase infusion using a new, site-specific drug delivery system: The Dispatch catheter. Cathet. Cardiovasc. Diagn. 33, 181-188.
    • (1994) Cathet. Cardiovasc. Diagn. , vol.33 , pp. 181-188
    • McKay, R.G.1    Fram, D.B.2    Hirst, J.A.3
  • 28
    • 0032401551 scopus 로고    scopus 로고
    • Ex vivo gene transfer of endothelial nitric oxide synthase to atherosclerotic rabbit aortic rings improves relaxations to acetylcholine
    • Mozes, G., Kullo, I.J., Mohacsi, T.G., et al. (1998). Ex vivo gene transfer of endothelial nitric oxide synthase to atherosclerotic rabbit aortic rings improves relaxations to acetylcholine. Atherosclerosis 141, 265-271.
    • (1998) Atherosclerosis , vol.141 , pp. 265-271
    • Mozes, G.1    Kullo, I.J.2    Mohacsi, T.G.3
  • 29
    • 14944349322 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene transfer restores endothelium-dependent relaxations and attenuates lesion formation in carotid arteries in apolipoprotein E-deficient mice
    • Mujynya-Ludunge, K., Viswambharan, H., Driscoll, R., et al. (2005). Endothelial nitric oxide synthase gene transfer restores endothelium-dependent relaxations and attenuates lesion formation in carotid arteries in apolipoprotein E-deficient mice. Basic Res. Cardiol. 100, 102-111.
    • (2005) Basic Res. Cardiol. , vol.100 , pp. 102-111
    • Mujynya-Ludunge, K.1    Viswambharan, H.2    Driscoll, R.3
  • 30
    • 0024392603 scopus 로고
    • Recombinant gene expression in vivo within endothelial cells of the arterial wall
    • Nabel, E.G., Plautz, G., Boyce, F.M., et al. (1989). Recombinant gene expression in vivo within endothelial cells of the arterial wall. Science 244, 1342-1344.
    • (1989) Science , vol.244 , pp. 1342-1344
    • Nabel, E.G.1    Plautz, G.2    Boyce, F.M.3
  • 31
    • 0028883466 scopus 로고
    • Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia
    • Newman, K.D., Dunn, P.F., Owens, J.W., et al. (1995). Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia. J. Clin. Invest. 96, 2955-2965.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2955-2965
    • Newman, K.D.1    Dunn, P.F.2    Owens, J.W.3
  • 32
    • 67650391207 scopus 로고    scopus 로고
    • Nitric oxide synthase gene therapy: Progress and prospects
    • O'Connor, D.M., and O'Brien, T. (2009). Nitric oxide synthase gene therapy: progress and prospects. Expert Opin. Biol. Ther. 9, 867-878.
    • (2009) Expert Opin. Biol. Ther. , vol.9 , pp. 867-878
    • O'Connor, D.M.1    O'Brien, T.2
  • 33
    • 0027242030 scopus 로고
    • Hypercholesterolemia increases endothelial superoxide anion production
    • Ohara, Y., Peterson, T.E., and Harrison, D.G. (1993). Hypercholesterolemia increases endothelial superoxide anion production. J. Clin. Invest. 91, 2546-2551.
    • (1993) J. Clin. Invest. , vol.91 , pp. 2546-2551
    • Ohara, Y.1    Peterson, T.E.2    Harrison, D.G.3
  • 34
    • 0032535435 scopus 로고    scopus 로고
    • Hypotension and reduced nitric oxide-elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase
    • Ohashi, Y., Kawashima, S., Hirata, K., et al. (1998). Hypotension and reduced nitric oxide-elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase. J. Clin. Invest. 102, 2061-2071.
    • (1998) J. Clin. Invest. , vol.102 , pp. 2061-2071
    • Ohashi, Y.1    Kawashima, S.2    Hirata, K.3
  • 35
    • 0031692410 scopus 로고    scopus 로고
    • Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery after experimental subarachnoid hemorrhage
    • discussion 1965-1966
    • Onoue, H., Tsutsui, M., Smith, L., et al. (1998). Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery after experimental subarachnoid hemorrhage. Stroke 29, 1959-1965; discussion 1965-1966.
    • (1998) Stroke , vol.29 , pp. 1959-1965
    • Onoue, H.1    Tsutsui, M.2    Smith, L.3
  • 36
    • 0031798450 scopus 로고    scopus 로고
    • Improvement of relaxation in an atherosclerotic artery by gene transfer of endothelial nitric oxide synthase
    • Ooboshi, H., Toyoda, K., Faraci, F.M., et al. (1998). Improvement of relaxation in an atherosclerotic artery by gene transfer of endothelial nitric oxide synthase. Arterioscler. Thromb. Vasc. Biol. 18, 1752-1758.
    • (1998) Arterioscler. Thromb. Vasc. Biol. , vol.18 , pp. 1752-1758
    • Ooboshi, H.1    Toyoda, K.2    Faraci, F.M.3
  • 37
    • 0036330231 scopus 로고    scopus 로고
    • Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice
    • Ozaki, M., Kawashima, S., Yamashita, T., et al. (2002). Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice. J. Clin. Invest. 110, 331-340.
    • (2002) J. Clin. Invest. , vol.110 , pp. 331-340
    • Ozaki, M.1    Kawashima, S.2    Yamashita, T.3
  • 38
    • 13844251902 scopus 로고    scopus 로고
    • Helper-dependent adenoviral vectors for gene therapy
    • Palmer, D.J., and Ng, P. (2005). Helper-dependent adenoviral vectors for gene therapy. Hum. Gene Ther. 16, 1-16.
    • (2005) Hum. Gene Ther. , vol.16 , pp. 1-16
    • Palmer, D.J.1    Ng, P.2
  • 39
    • 0030462599 scopus 로고    scopus 로고
    • A helper-dependent adenovirus vector system: Removal of helper virus by Cremediated excision of the viral packaging signal
    • Parks, R.J., Chen, L., Anton, M., et al. (1996). A helper-dependent adenovirus vector system: Removal of helper virus by Cremediated excision of the viral packaging signal. Proc. Natl. Acad. Sci. U. S. A. 93, 13565-13570.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 13565-13570
    • Parks, R.J.1    Chen, L.2    Anton, M.3
  • 40
    • 0033564035 scopus 로고    scopus 로고
    • Nitric oxide synthase gene therapy rapidly reduces adhesion molecule expression and inflammatory cell infiltration in carotid arteries of cholesterol-fed rabbits
    • Qian, H., Neplioueva, V., Shetty, G.A., et al. (1999). Nitric oxide synthase gene therapy rapidly reduces adhesion molecule expression and inflammatory cell infiltration in carotid arteries of cholesterol-fed rabbits. Circulation 99, 2979-2982.
    • (1999) Circulation , vol.99 , pp. 2979-2982
    • Qian, H.1    Neplioueva, V.2    Shetty, G.A.3
  • 41
    • 0035844088 scopus 로고    scopus 로고
    • Improved adenoviral vector for vascular gene therapy: Beneficial effects on vascular function and inflammation
    • Qian, H.S., Channon, K., Neplioueva, V., et al. (2001). Improved adenoviral vector for vascular gene therapy: Beneficial effects on vascular function and inflammation. Circ. Res. 88, 911-917.
    • (2001) Circ. Res. , vol.88 , pp. 911-917
    • Qian, H.S.1    Channon, K.2    Neplioueva, V.3
  • 42
    • 0025366847 scopus 로고
    • An Larginine/ nitric oxide pathway present in human platelets regulates aggregation
    • Radomski, M.W., Palmer, R.M., and Moncada, S. (1990). An Larginine/ nitric oxide pathway present in human platelets regulates aggregation. Proc. Natl. Acad. Sci. U. S. A. 87, 5193-5197.
    • (1990) Proc. Natl. Acad. Sci. U. S. A. , vol.87 , pp. 5193-5197
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 43
    • 0028177464 scopus 로고
    • Anatomic barriers influence the distribution of in vivo gene transfer into the arterial wall. Modeling with microscopic tracer particles and verification with a recombinant adenoviral vector
    • Rome, J.J., Shayani, V., Flugelman, M.Y., et al. (1994). Anatomic barriers influence the distribution of in vivo gene transfer into the arterial wall. Modeling with microscopic tracer particles and verification with a recombinant adenoviral vector. Arterioscler. Thromb. 14, 148-161.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 148-161
    • Rome, J.J.1    Shayani, V.2    Flugelman, M.Y.3
  • 44
    • 12944315064 scopus 로고    scopus 로고
    • Optimization of the helper-dependent adenovirus system for production and potency in vivo
    • Sandig, V., Youil, R., Bett, A.J., et al. (2000). Optimization of the helper-dependent adenovirus system for production and potency in vivo. Proc. Natl. Acad. Sci. U. S. A. 97, 1002-1007.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 1002-1007
    • Sandig, V.1    Youil, R.2    Bett, A.J.3
  • 45
    • 0033961047 scopus 로고    scopus 로고
    • Expression of Fas ligand in arteries of hypercholesterolemic rabbits accelerates atherosclerotic lesion formation
    • Schneider, D.B., Vassalli, G., Wen, S., et al. (2000). Expression of Fas ligand in arteries of hypercholesterolemic rabbits accelerates atherosclerotic lesion formation. Arterioscler. Thromb. Vasc. Biol. 20, 298-308.
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 298-308
    • Schneider, D.B.1    Vassalli, G.2    Wen, S.3
  • 46
    • 0029095454 scopus 로고
    • Endothelium-specific in vivo gene transfer
    • Schulick, A.H., Dong, G., Newman, K.D., et al. (1995). Endothelium-specific in vivo gene transfer. Circ. Res. 77, 475-485.
    • (1995) Circ. Res. , vol.77 , pp. 475-485
    • Schulick, A.H.1    Dong, G.2    Newman, K.D.3
  • 47
    • 84858004765 scopus 로고    scopus 로고
    • Geneeluting stents: Non-viral, liposome-based gene delivery of eNOS to the blood vessel wall in vivo results in enhanced endothelialization but does not reduce restenosis in a hypercholesterolemic model
    • Sharif, F., Hynes, S.O., McCullagh, K.J., et al. (2012). Geneeluting stents: non-viral, liposome-based gene delivery of eNOS to the blood vessel wall in vivo results in enhanced endothelialization but does not reduce restenosis in a hypercholesterolemic model. Gene Ther. 19, 321-328.
    • (2012) Gene Ther. , vol.19 , pp. 321-328
    • Sharif, F.1    Hynes, S.O.2    McCullagh, K.J.3
  • 48
    • 34250836426 scopus 로고    scopus 로고
    • A specific role for eNOS-derived reactive oxygen species in atherosclerosis progression
    • Takaya, T., Hirata, K., Yamashita, T., et al. (2007). A specific role for eNOS-derived reactive oxygen species in atherosclerosis progression. Arterioscler. Thromb. Vasc. Biol. 27, 1632-1637.
    • (2007) Arterioscler. Thromb. Vasc. Biol. , vol.27 , pp. 1632-1637
    • Takaya, T.1    Hirata, K.2    Yamashita, T.3
  • 49
    • 68849128353 scopus 로고    scopus 로고
    • DRG-targeted helper-dependent adenoviruses mediate selective gene delivery for therapeutic rescue of sensory neuronopathies in mice
    • Terashima, T., Oka, K., Kritz, A.B., et al. (2009). DRG-targeted helper-dependent adenoviruses mediate selective gene delivery for therapeutic rescue of sensory neuronopathies in mice. J. Clin. Invest. 119, 2100-2112.
    • (2009) J. Clin. Invest. , vol.119 , pp. 2100-2112
    • Terashima, T.1    Oka, K.2    Kritz, A.B.3
  • 50
    • 0028798793 scopus 로고
    • Gene therapy inhibiting neointimal vascular lesion: In vivo transfer of endothelial cell nitric oxide synthase gene
    • von der Leyen, H.E., Gibbons, G.H., Morishita, R., et al. (1995). Gene therapy inhibiting neointimal vascular lesion: In vivo transfer of endothelial cell nitric oxide synthase gene. Proc. Natl. Acad. Sci. U. S. A. 92, 1137-1141.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 1137-1141
    • Von Der Leyen, H.E.1    Gibbons, G.H.2    Morishita, R.3
  • 51
    • 1042298185 scopus 로고    scopus 로고
    • Adenoviral transfer of endothelial nitric oxide synthase attenuates lesion formation in a novel murine model of postangioplasty restenosis
    • von der Thu sen, J.H., Fekkes, M.L., Passier, R., et al. (2004). Adenoviral transfer of endothelial nitric oxide synthase attenuates lesion formation in a novel murine model of postangioplasty restenosis. Arterioscler. Thromb. Vasc. Biol. 24, 357-362.
    • (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24 , pp. 357-362
    • Von Der Thusen, J.H.1    Fekkes, M.L.2    Passier, R.3
  • 52
    • 0030161017 scopus 로고    scopus 로고
    • Second-generation adenovirus vectors
    • Wang, Q., and Finer, M.H. (1996). Second-generation adenovirus vectors. Nat. Med. 2, 714-716.
    • (1996) Nat. Med. , vol.2 , pp. 714-716
    • Wang, Q.1    Finer, M.H.2
  • 53
    • 0034082167 scopus 로고    scopus 로고
    • Secondgeneration adenoviral vectors do not prevent rapid loss of transgene expression and vector DNA from the arterial wall
    • Wen, S., Schneider, D.B., Driscoll, R.M., et al. (2000). Secondgeneration adenoviral vectors do not prevent rapid loss of transgene expression and vector DNA from the arterial wall. Arterioscler. Thromb. Vasc. Biol. 20, 1452-1458.
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 1452-1458
    • Wen, S.1    Schneider, D.B.2    Driscoll, R.M.3
  • 54
    • 0035569961 scopus 로고    scopus 로고
    • Inclusion of the E3 region in an adenoviral vector decreases inflammation and neointimal formation after arterial gene transfer
    • Wen, S., Driscoll, R.M., Schneider, D.B., and Dichek, D. (2001). Inclusion of the E3 region in an adenoviral vector decreases inflammation and neointimal formation after arterial gene transfer. Arterioscler. Thromb. Vasc. Biol. 21, 1777-1782.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 1777-1782
    • Wen, S.1    Driscoll, R.M.2    Schneider, D.B.3    Dichek, D.4
  • 55
    • 4544329958 scopus 로고    scopus 로고
    • Improved vascular gene transfer with a helper-dependent adenoviral vector
    • Wen, S., Graf, S., Massey, P.G., and Dichek, D.A. (2004). Improved vascular gene transfer with a helper-dependent adenoviral vector. Circulation 110, 1484-1491.
    • (2004) Circulation , vol.110 , pp. 1484-1491
    • Wen, S.1    Graf, S.2    Massey, P.G.3    Dichek, D.A.4
  • 56
    • 0033859852 scopus 로고    scopus 로고
    • Mechanisms of reduced nitric oxide/cGMP-mediated vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase
    • Yamashita, T., Kawashima, S., Ohashi, Y., et al. (2000). Mechanisms of reduced nitric oxide/cGMP-mediated vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase. Hypertension 36, 97-102.
    • (2000) Hypertension , vol.36 , pp. 97-102
    • Yamashita, T.1    Kawashima, S.2    Ohashi, Y.3
  • 57
    • 0034650348 scopus 로고    scopus 로고
    • Cardiovascular gene therapy
    • Yla-Herttuala, S., and Martin, J.F. (2000). Cardiovascular gene therapy. Lancet 355, 213-222.
    • (2000) Lancet , vol.355 , pp. 213-222
    • Yla-Herttuala, S.1    Martin, J.F.2
  • 58
    • 0037628872 scopus 로고    scopus 로고
    • In vivo gene transfer of inducible nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits
    • Zanetti, M., d'Uscio, L.V., Kovesdi, I., et al. (2003). In vivo gene transfer of inducible nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits. Stroke 34, 1293-1298.
    • (2003) Stroke , vol.34 , pp. 1293-1298
    • Zanetti, M.1    D'Uscio, L.V.2    Kovesdi, I.3
  • 59
    • 0029047323 scopus 로고
    • Nitric oxide modulates the expression of monocyte chemoattractant protein 1 in cultured human endothelial cells
    • Zeiher, A.M., Fisslthaler, B., Schray-Utz, B., and Busse, R. (1995). Nitric oxide modulates the expression of monocyte chemoattractant protein 1 in cultured human endothelial cells. Circ. Res. 76, 980-986.
    • (1995) Circ. Res. , vol.76 , pp. 980-986
    • Zeiher, A.M.1    Fisslthaler, B.2    Schray-Utz, B.3    Busse, R.4
  • 60
    • 33646544087 scopus 로고    scopus 로고
    • TNF-alpha contributes to endothelial dysfunction in ischemia/reperfusion injury
    • Zhang, C., Xu, X., Potter, B.J., et al. (2006). TNF-alpha contributes to endothelial dysfunction in ischemia/reperfusion injury. Arterioscler. Thromb. Vasc. Biol. 26, 475-480.
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 475-480
    • Zhang, C.1    Xu, X.2    Potter, B.J.3


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