Vasomotor dysfunction early after exposure of normal rabbit arteries to an adenoviral vector

Human Gene Therapy

Volumn 8, Issue 9, 1997, Pages 1033-1040

  Lafont, Antoine ^a   Loirand, Gervaise ^b   Pacaud, Pierre ^b   Vilde, Françoise ^a   Lemarchand, Patricia ^c   Escande, Denis ^d  

^a Hopital Boucicaut   (France)

^b INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c INSERM   (France)

^d CHU de Nantes   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA GALACTOSIDASE; BRIMONIDINE; CALCIMYCIN; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; POTASSIUM CHLORIDE;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; EAR ARTERY; EXPRESSION VECTOR; FEMORAL ARTERY; GENE TRANSFER; HISTOCHEMISTRY; INFLAMMATORY CELL; NONHUMAN; RABBIT; REPORTER GENE; VASOMOTOR REFLEX; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0030742242     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1997.8.9-1033     Document Type: Article

References (35)

1. BEASLEY, D., SCHWARTZ, J.H., and BRENNER, B.M. (1991). Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells. J. Clin. Invest. 87, 602-608.
2. BUSSE, R., and MÜLSCH, A. (1990). Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells. FEBS Lett. 275, 87-90.
3. DANNENBERG, A.M., and SUGA, M. (1981). Histochemical stains for macrophages in cell smears and tissue sections: β-Galactosidase, acid phosphatase, nonspecific esterase, succinic dehydrogenase, and cytochrome oxidase. In Methods for Studying Mononuclear Phagocytes. D.O. Adams, P.J. Edelson, and H.S. Koren, eds. (Academic Press, New York) pp. 375-395.
4. DION, L.D., FANG, J., and GARVER, R.I. (1996). Supernatant rescue assay vs. polymerase chain reaction for detection of wild type adenovirus-contaminating recombinant adenovirus stocks. J. Virol. Methods 56, 99-103.
5. EISSA, N.T., CHU, C.S., DANEL, C., and CRYSTAL, R.G. (1994). Evaluation of respiratory epithelium of normals and individuals with cystic fibrosis for the presence of adenovirus E1a sequences relevant to the use of E1a- adenovinis vectors for gene therapy for the respiratory manifestations of cystic fibrosis. Hum. Gene Ther. 5, 1105-1114.
6. ERZURUM, S.C., LEMARCHAND, P., ROSENFELD, M.A., YOO, J-H., and CRYSTAL, R.G. (1993). Protection of human endothelial cells from oxidant injury by adenovirus-mediated transfer of the human catalase cDNA. Nucleic Acids Res. 21, 1607-1612.
7. FISHER, K.J., CHOI, H., BURDA, J., CHEN, S-J., and WILSON, J.M. (1996). Recombinant adenovirus deleted of all viral genes for gene therapy for cystic fibrosis. Virology 217, 11-22.
8. FLAVAHAN, N.A., and VANHOUTTE, P.M. (1986). Alpha-1 and Alpha-2 adrenoceptor: response coupling in canine saphenous and femoral veins. J. Pharmacol. Exper. Ther. 239, 784-789.
9. GRAHAM, F.L., and PREVEC, L. (1992). Adenovirus-based expression vectors and recombinant vaccines. In New Approaches to Immunological Problems. R.W. Ellis, ed. (Butterworth-Heinemann, Boston, MA) pp. 363-390.
10. GUZMAN, R.J., LEMARCHAND, P., CRYSTAL, R.G., EPSTEIN, S.E., and FINKEL, T. (1993). Efficient and selective adenovirus-mediated gene transfer into vascular neointima. Circulation 88, 2838-2848.
11. LEE, S.W., TRAPNELL, B.C., RADE, J.J., VIRMANI, R., and DICHEK, D.A. (1993). In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries. Circ. Res. 73, 797-807.
12. LEMARCHAND, P., JONES, M., YAMADA, I., and CRYSTAL, R.G. (1993). In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors. Circ. Res. 72, 1132-1138.
13. LENNON, P.F., COLLARD, C.D., MORISSEY, M.A., and STAHL, G.L. (1996). Complement-induced endothelial dysfunction in rabbits: Mechanisms, recovery, and gender differences. Am. J. Physiol. 270, H1924-H1932.
14. LOSORDO, D.W., PICKERING, J.G., TAKESHITA, S., LECLERC, G., GAL, D., WEIR, L., KEARNEY, M., JEKANOWSKI, J., and ISNER, J.M. (1994). Use of the rabbit ear artery to serially assess foreign protein secretion after site-specific arterial gene transfer in vivo. Evidence that anatomic identification of successful gene transfer may underestimate the potential magnitude of transgene expression. Circulation 89, 785-792.
15. MARCH, K.L., MADISON, J.E., and TRAPNELL, B.C. (1995). Pharmacokinetics of adenoviral vector-mediated gene delivery to vascular smooth muscle cells: Modulation by poloxamer 407 and implications for cardiovascular gene therapy. Hum. Gene Ther. 6, 41-53.
16. MASTRANGELI, A., DANEL, C., ROSENFELD, M.A., STRATFORD-PERRICAUDET, L., PERRICAUDET, M., PAVIRANI, A., LECOCQ, J-P., and CRYSTAL, R.G. (1993). Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer. J. Clin. Invest. 91, 225-234.
17. MC COY, R.D., DAVIDSON, B.L., ROESSELR, B.J., HUFFNAGLE, G.B., JANICH, S.L., LAING, T.J., and SIMON, R.H. (1995). Pulmonary inflammation induced by incomplete or inactivated adenoviral particles. Hum. Gene Ther. 6, 1553-1560.
18. MC GROGY, W.J., BAUTISTA, D.S., and GRAHAM, F.L. (1988). A simple technique for the rescue of early region I Mutations into infectious human adenovirus type 5. Virology 163, 614-617.
19. MITTEREDER, N., MARCH, K.L., and TRAPNELL, B.C. (1996). Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy. J. Virol. 70, 7498-7509.
20. MONCADA, S., PALMER, R.M.J., and HIGGS, E.A. (1991). Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev. 43, 109-142.
21. MULLER, D.W., GORDON, D., SAN, H., YANG, Z., POMPILI, V.J., NABEL, G.J., and NABEL, E.G. (1994). Catheter-mediated pulmonary vascular gene transfer and expression. Circ. Res. 75, 1039-1049.
22. MYERS, P.R., ZHONG, Q., JONES, J.J., TANNER, M.A., ADAMS, H.R., and PARKER, J.L. (1995). Release of EDRF and NO in ex vivo perfused aorta: inhibition by in vivo E. coli endotoxemia. Am. J. Physiol. 268, H955-H961.
23. NABEL, E.G. (1995). Gene therapy for cardiovascular disease. Circulation 91, 541-548.
24. NEWMAN, K.D., DUNN, P.F., OWENS, J.W., SCHULICK, A.H., VIRMANI, R., SUKHOVA, G., LIBBY, P., and DICHEK, D.A. (1995). Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia. J. Clin. Invest. 96, 2955-2965.
25. PARKER, J.L., and ADAMS, H.R. (1993). Selective inhibition of endothelium-dependent vasodilator capacity by Escherichia coli endotoxemia. Circ. Res. 72, 539-551.
26. RAPOPORT, R.M., and MURAD, F. (1983). Agonist induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cyclic GMP. Circ. Res. 52, 352-357.
27. REES, D.D., CELLEK, S., PALMER, R.M.J., and MONCADA, S. (1990). Dexamethasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone. An insight into endotoxin shock. Biochem. Biophys. Res. Commun. 173, 541-547.
28. ROME, J.J., SHAYANI, V., NEWMAN, K.D., FARRELL, S., LEE, S.W., VIRMANI, R., and DICHEK, D.A. (1994). Adenoviral vector-mediated gene transfer into sheep arteries using a double-balloon catheter. Hum. Gene Ther. 5, 1249-1258.
29. SCHACHTNER, S.K., ROME, J.J., HOYT, R.F., JR., NEWMAN, K.D., VIRMANI, R., and DICHEK, D.A. (1995). In vivo adenovirus-mediated gene transfer via the pulmonary artery of rats. Circ. Res. 76, 701-709.
30. SCHULICK, A.H., DONG, G., NEWMAN, K.D., VIRMANI, R., and DICHEK, D.A. (1995a). Endothelium-specific in vivo gene transfer. Circ. Res. 77, 475-485.
31. SCHULICK, A.H., NEWMAN, K.D., VIRMANI, R., and DICHEK, D.A. (1995b). In vivo gene transfer into injured carotid arteries. Optimization and evaluation of acute toxicity. Circulation 91, 2407-2414.
32. STEG, P.G., FELDMAN, L.J., SCOAZEC, J.Y., TAHLIL, O., BARRY, J.J., BOULECHFAR, S., RAGOT, T., ISNER, J.M., and PERRICAUDET, M. (1994). Arterial gene transfer to rabbit endothelial and smooth muscle cells using percutaneous delivery of an adenoviral vector. Circulation 90, 1648-1656.
33. STRATFORD-PERRICAUDET, L.D., MAKEH, I., PERRICAUDET, M., and BRIAND, P. (1992). Widespread long-term gene transfer to mouse skeletal muscles and heart. J. Clin. Invest. 90, 626-630.
34. WANG, P., BA, Z.F., and CHAUDRY, I.H. (1994). Administration of tumor necrosis factor-alpha in vivo depresses endothelium-dependent relaxation. Am. J. Physiol. 266, H2535-H2541.
35. WILLARD, J.E., LANDAU, C., GLAMANN, D.B., BURNS, D., JESSEN, M.E., PIRWITZ, M.J., GERARD, R.D., and MEIDELL, R.S. (1994). Genetic modification of the vessel wall. Comparison of surgical and catheter-based techniques for delivery of recombinant adenovirus. Circulation 89, 2190-2197.