Tyrosine phosphorylation of the p21 cyclin-dependent kinase inhibitor facilitates the development of proneural glioma

Journal of Biological Chemistry

Volumn 287, Issue 46, 2012, Pages 38523-38530

  Hukkelhoven, Ellen ^a   Liu, Yuhui ^a,c   Yehs, Nancy ^a   Ciznadijas, Daniel ^a   Blain, Stacy W ^b   Koffs, Andrew ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b SUNY DOWNSTATE MEDICAL CENTER   (United States)

^c Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE SUBSTITUTION; ANIMAL MODEL; CDK INHIBITORS; CYCLIN-DEPENDENT KINASE; CYCLIN-DEPENDENT KINASE INHIBITORS; CYCLIND1; INHIBITORY ACTIVITY; MOUSE MODELS; ONCOGENIC ACTIVITIES; TUMOR CELLS; TUMOR DEVELOPMENT; TUMOR FORMATION; TYROSINE PHOSPHORYLATION; VAN DER WAALS;

AMINO ACIDS; HYDROGEN BONDS; PHOSPHORYLATION; VAN DER WAALS FORCES;

TUMORS;

CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1; TYROSINE;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GLIOMA; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR PROMOTION;

AMINO ACID SEQUENCE; ANIMALS; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM NEOPLASMS; CYCLIN D1; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; GLIOMA; HEK293 CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; TYROSINE;

ANIMALIA;

EID: 84869006754     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.366542     Document Type: Article

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