Critical role for the helix region of p57(Kip2) in cyclin-dependent kinase 2 inhibition and growth suppression

Journal of Biological Chemistry

Volumn 273, Issue 26, 1998, Pages 16544-16550

  Hashimoto, Y ^a   Kohri, K ^a   Kaneko, Y ^a   Morisaki, H ^a   Kato, T ^a   Ikeda, K ^a   Nakanishi, M ^a  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; ADENOSINE TRIPHOSPHATE; CYCLIN A; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1C; CYCLIN E; ENZYME INHIBITOR; GROWTH INHIBITOR; NUCLEAR PROTEIN; PROTEIN SERINE THREONINE KINASE;

ARTICLE; CELL CYCLE; CRYSTAL STRUCTURE; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GROWTH REGULATION; NONHUMAN; PRIORITY JOURNAL; AMINO ACID SEQUENCE; ANIMAL; ARMYWORM; BACULOVIRUS; BINDING SITE; CHEMISTRY; DRUG ANTAGONISM; ESCHERICHIA COLI; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; BACULOVIRIDAE; BINDING SITES; CDC2-CDC28 KINASES; CRYSTALLOGRAPHY, X-RAY; CYCLIN A; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P57; CYCLIN-DEPENDENT KINASES; ENZYME INHIBITORS; ESCHERICHIA COLI; GROWTH INHIBITORS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR PROTEINS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN-SERINE-THREONINE KINASES; SEQUENCE ALIGNMENT; SPODOPTERA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032568666     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.26.16544     Document Type: Article

References (29)