Expression of Concern: Mitotically inactivated embryonic stem cells can be used as an in vivo feeder layer to nurse damaged myocardium after acute myocardial infarction: a preclinical study (Circulation Research (2012) 111 (1286-1296) DOI: 10.1161/CIRCRESAHA.111.262584);Mitotically inactivated embryonic stem cells can be used as an in vivo feeder layer to nurse damaged myocardium after acute myocardial infarction: A preclinical study

Circulation Research

Volumn 111, Issue 10, 2012, Pages 1286-1296

  Burt, Richard K ^a   Chen, You Hong ^b   Verda, Larissa ^a   Lucena, Carolina ^c   Navale, Shankararao ^b   Johnson, Jesse ^b   Han, Xiaoqiang ^a   Lomasney, Jon ^a   Baker, Jessa M ^b   Ngai, Ka Leung ^d   Kino, Aya ^a   Carr, James ^a   Kajstura, Jan ^e   Anversa, Piero ^e  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Genani Corporation   (United States)

^c CECOLFES   (Colombia)

^d MegaBases Inc   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

acute myocardial infarction; embryonic stem cells; irradiated stem cells

Indexed keywords

BROMODEOXYCYTIDINE; DNA;

ACUTE HEART INFARCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CELL PROLIFERATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DNA SYNTHESIS; EMBRYONIC STEM CELL; FEEDER CELL; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION PROFILING; HEART FUNCTION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HUMAN; HUMAN CELL; IN VIVO STUDY; IRRADIATION; MALE; MICROARRAY ANALYSIS; MITOSIS; MOUSE; NONHUMAN; NURSE; PRIORITY JOURNAL; RHESUS MONKEY; SOMATIC CELL; Y CHROMOSOME;

EID: 84868700636     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/RES.0000000000000241     Document Type: Erratum

References (41)

1. Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I, Quaini F, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA. 2001;98:10344-10349. (Pubitemid 32803022)
2. Burt RK, Loh Y, Pearce W, Beohar N, Barr WG, Craig R, Wen Y, Rapp JA, Kessler J. Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant diseases. JAMA. 2008;299:925-936. (Pubitemid 351397068)
3. Kocher AA, Schuster MD, Szabolcs MJ, Takuma S, Burkhoff D, Wang J, Homma S, Edwards NM, Itescu S. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents car-diomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med. 2001;7:430-436. (Pubitemid 32298545)
4. Jackson KA, Majka SM, Wang H, Pocius J, Hartley CJ, Majesky MW, Entman ML, Michael LH, Hirschi KK, Goodell MA. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest. 2001;107:1395-1402. (Pubitemid 32522033)
5. Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B, Pickel J, McKay R, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. Bone marrow cells regenerate infarcted myocardium. Nature. 2001;410:701-705. (Pubitemid 32290358)
6. Krause DS, Theise ND, Collector MI, Henegariu O, Hwang S, Gardner R, Neutzel S, Sharkis SJ. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell. 2001;105:369-377. (Pubitemid 32455343)
7. Rota M, Kajstura J, Hosoda T, et al. Bone marrow cells adopt the cardio-myogenic fate in vivo. Proc Natl Acad Sci USA. 2007;104:17783-17788. (Pubitemid 350210912)
8. Alvarez-Dolado M, Pardal R, Garcia-Verdugo JM, Fike JR, Lee HO, Pfeffer K, Lois C, Morrison SJ, Alvarez-Buylla A. Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepa-tocytes. Nature. 2003;425:968-973. (Pubitemid 37376928)
9. Ishikawa F, Shimazu H, Shultz LD, Fukata M, Nakamura R, Lyons B, Shimoda K, Shimoda S, Kanemaru T, Nakamura K, Ito H, Kaji Y, Perry AC, Harada M. Purifed human hematopoietic stem cells contrib ute to the generation of cardiomyocytes through cell fusion. FASEB J. 2006;20:950-952.
10. Murry CE, Soonpaa MH, Reinecke H, Nakajima H, Nakajima HO, Rubart M, Pasumarthi KB, Virag JI, Bartelmez SH, Poppa V, Bradford G, Dowell JD, Williams DA, Field LJ. Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature. 2004;428:664-668. (Pubitemid 38524810)
11. Nygren JM, Jovinge S, Breitbach M, Säwén P, Röll W, Hescheler J, Taneera J, Fleischmann BK, Jacobsen SE. Bone marrow-derived hema-topoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation. Nat Med. 2004;10:494-501. (Pubitemid 38667908)
12. Nygren JM, Liuba K, Breitbach M, Stott S, Thorén L, Roell W, Geisen C, Sasse P, Kirik D, Björklund A, Nerlov C, Fleischmann BK, Jovinge S, Jacobsen SE. Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion. Nat Cell Biol. 2008;10:584-592. (Pubitemid 351627378)
13. Mangi AA, Noiseux N, Kong D, He H, Rezvani M, Ingwall JS, Dzau VJ. Mesenchymal stem cells modifed with Akt prevent remodeling and restore performance of infarcted hearts. Nat Med. 2003;9:1195-1201. (Pubitemid 37173705)
14. Sussman MA, Murry CE. Bones of contention: marrow-derived cells in myocardial regeneration. J Mol Cell Cardiol. 2008;44:950-953.
15. Hoofnagle MH, Wamhoff BR, Owens GK. Lost in transdifferentiation. J Clin Invest. 2004;113:1249-1251. (Pubitemid 39069920)
16. Behfar A, Hodgson DM, Zingman LV, Perez-Terzic C, Yamada S, Kane GC, Alekseev AE, Pucéat M, Terzic A. Administration of allogenic stem cells dosed to secure cardiogenesis and sustained infarct repair. Ann N Y Acad Sci. 2005;1049:189-198. (Pubitemid 40967586)
17. Nussbaum J, Minami E, Lafamme MA, Virag JA, Ware CB, Masino A, Muskheli V, Pabon L, Reinecke H, Murry CE. Transplantation of undif-ferentiated murine embryonic stem cells in the heart: teratoma formation and immune response. FASEB J. 2007;21:1345-1357. (Pubitemid 46684837)
18. Leor J, Gerecht S, Cohen S, Miller L, Holbova R, Ziskind A, Shachar M, Feinberg MS, Guetta E, Itskovitz-Eldor J. Human embryonic stem cell transplantation to repair the infarcted myocardium. Heart. 2007;93:1278-1284. (Pubitemid 47492921)
19. Lafamme MA, Chen K Y, Naumova AV, et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol. 2007;25:1015-1024. (Pubitemid 47517637)
20. Mummery CL, Zhang J, Ng ES, Elliott DA, Elefanty AG, Kamp TJ. Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview. Circ Res. 2012;111:344-358.
21. Thew M, Seymour E. The science and ethics of primate research. Lancet. 2009;374:607-608.
22. Traverse JH, Henry TD, Ellis SG, et al; Cardiovascular Cell Therapy Research Network. Effect of intracoronary delivery of autologous bone marrow mononuclear cells 2 to 3 weeks following acute myocardial infarction on left ventricular function: the LateTIME randomized trial. JAMA. 2011;306:2110-2119.
23. Thum T, Bauersachs J, Poole-Wilson PA, Volk HD, Anker SD. The dying stem cell hypothesis: immune modulation as a novel mechanism for progenitor cell therapy in cardiac muscle. J Am Coll Cardiol. 2005;46:1799-1802. (Pubitemid 41579799)
24. Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, Chimenti S, Kasahara H, Rota M, Musso E, Urbanek K, Leri A, Kajstura J, Nadal-Ginard B, Anversa P. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell. 2003;114:763-776. (Pubitemid 37186770)
25. Oh H, Bradfute SB, Gallardo TD, Nakamura T, Gaussin V, Mishina Y, Pocius J, Michael LH, Behringer RR, Garry DJ, Entman ML, Schneider MD. Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci USA. 2003;100:12313-12318. (Pubitemid 37271557)
26. Martin CM, Meeson AP, Robertson SM, Hawke TJ, Richardson JA, Bates S, Goetsch SC, Gallardo TD, Garry DJ. Persistent expression of the ATP-binding cassette transporter, Abcg2, identifes cardiac SP cells in the developing and adult heart. Dev Biol. 2004;265:262-275. (Pubitemid 38018836)
27. Bearzi C, Rota M, Hosoda T, et al. Human cardiac stem cells. Proc Natl Acad Sci USA. 2007;104:14068-14073. (Pubitemid 350003336)
28. Gonzalez A, Rota M, Nurzynska D, et al. Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan. Circ Res. 2008;102:597-606. (Pubitemid 351416761)
29. Murry CE, Kühn B. Taking a load off: nuclear remodeling after mechanically supporting the failing human heart. Circulation. 2010;121:957-959.
30. Palmer TD, Willhoite AR, Gage FH. Vascular niche for adult hippocam-pal neurogenesis. J Comp Neurol. 2000;425:479-494.
31. Smart N, Bollini S, Dubé KN, Vieira JM, Zhou B, Davidson S, Yellon D, Riegler J, Price AN, Lythgoe MF, Pu WT, Riley PR. De novo car-diomyocytes from within the activated adult heart after injury. Nature. 2011;474:640-644.
32. Gerdes HH, Bukoreshtliev NV, Barroso JF. Tunneling nanotubes: a new route for the exchange of components between animal cells. FEBS Lett. 2007;581:2194-2201. (Pubitemid 46709910)
33. Gurke S, Barroso JF, Gerdes HH. The art of cellular communication: tunneling nanotubes bridge the divide. Histochem Cell Biol. 2008;129:539-550.
34. Spees JL, Olson SD, Whitney MJ, Prockop DJ. Mitochondrial transfer between cells can rescue aerobic respiration. Proc Natl Acad Sci USA. 2006;103:1283-1288. (Pubitemid 43191157)
35. Rørth P. Communication by touch: role of cellular extensions in complex animals. Cell. 2003;112:595-598. (Pubitemid 36331772)
36. Collino F, Deregibus MC, Bruno S, Sterpone L, Aghemo G, Viltono L, Tetta C, Camussi G. Microvesicles derived from adult human bone marrow and tissue specifc mesenchymal stem cells shuttle selected pattern of miRNAs. PLoS ONE. 2010;5:e11803.
37. Bruno S, Grange C, Deregibus MC, Calogero RA, Saviozzi S, Collino F, Morando L, Busca A, Falda M, Bussolati B, Tetta C, Camussi G. Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol. 2009;20:1053-1067.
38. Gatti S, Bruno S, Deregibus MC, Sordi A, Cantaluppi V, Tetta C, Camussi G. Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury. Nephrol Dial Transplant. 2011;26:1474-1483.
39. Camussi G, Deregibus MC, Bruno S, Cantaluppi V, Biancone L. Exosomes/microvesicles as a mechanism of cell-to-cell communication. Kidney Int. 2010;78:838-848.
40. Deregibus MC, Cantaluppi V, Calogero R, Lo Iacono M, Tetta C, Biancone L, Bruno S, Bussolati B, Camussi G. Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA. Blood. 2007;110:2440-2448. (Pubitemid 47523165)
41. Neubauer S. The failing heart-an engine out of fuel. N Engl J Med. 2007;356:1140-1151. (Pubitemid 46425598)