메뉴 건너뛰기




Volumn 6, Issue 7, 2011, Pages

Amplified B lymphocyte CD40 signaling drives regulatory B10 cell expansion in mice

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CD40 LIGAND; IMMUNOGLOBULIN G; INTERLEUKIN 10; CD22 ANTIGEN; CD40 ANTIGEN;

EID: 79960728714     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022464     Document Type: Article
Times cited : (62)

References (54)
  • 2
    • 0027394391 scopus 로고
    • The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome
    • Aruffo A, Farrington M, Hollenbaugh D, Li X, Milatovich A, et al. (1993) The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome. Cell 72: 291-300.
    • (1993) Cell , vol.72 , pp. 291-300
    • Aruffo, A.1    Farrington, M.2    Hollenbaugh, D.3    Li, X.4    Milatovich, A.5
  • 3
    • 0027960913 scopus 로고
    • CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation
    • Castigli E, Alt FW, Davidson L, Bottaro A, Mizoguchi E, et al. (1994) CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation. Proc Natl Acad Sci USA 91: 12135-12139.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12135-12139
    • Castigli, E.1    Alt, F.W.2    Davidson, L.3    Bottaro, A.4    Mizoguchi, E.5
  • 4
    • 0028447437 scopus 로고
    • The immune responses in the CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation
    • Kawabe T, Naka T, Yoshida K, Tanaka T, Fujiwara H, et al. (1994) The immune responses in the CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation. Immunity 1: 167-178.
    • (1994) Immunity , vol.1 , pp. 167-178
    • Kawabe, T.1    Naka, T.2    Yoshida, K.3    Tanaka, T.4    Fujiwara, H.5
  • 5
    • 0027236043 scopus 로고
    • B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40
    • Tsubata T, Wu J, Honjo T, (1993) B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40. Nature 12: 645-648.
    • (1993) Nature , vol.12 , pp. 645-648
    • Tsubata, T.1    Wu, J.2    Honjo, T.3
  • 8
    • 0031938031 scopus 로고    scopus 로고
    • Enhancement of T cell-independent immune responses in vivo by CD40 antibodies
    • Dullforce P, Sutton DC, Heath AW, (1998) Enhancement of T cell-independent immune responses in vivo by CD40 antibodies. Nat Med 4: 88-91.
    • (1998) Nat Med , vol.4 , pp. 88-91
    • Dullforce, P.1    Sutton, D.C.2    Heath, A.W.3
  • 9
    • 0033748344 scopus 로고    scopus 로고
    • B cell immunopoiesis: visualizing the impact of CD40 engagement on the course of T cell-independent immune responses in an Ig transgenic system
    • Erickson LD, Vogel LA, Cascalho M, Wong J, Wabl M, et al. (2000) B cell immunopoiesis: visualizing the impact of CD40 engagement on the course of T cell-independent immune responses in an Ig transgenic system. Eur J Immunol 30: 3121-3131.
    • (2000) Eur J Immunol , vol.30 , pp. 3121-3131
    • Erickson, L.D.1    Vogel, L.A.2    Cascalho, M.3    Wong, J.4    Wabl, M.5
  • 12
    • 0032896709 scopus 로고    scopus 로고
    • CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help
    • French RR, Chan HT, Tutt AL, Glennie MJ, (1999) CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help. Nat Med 5: 548-553.
    • (1999) Nat Med , vol.5 , pp. 548-553
    • French, R.R.1    Chan, H.T.2    Tutt, A.L.3    Glennie, M.J.4
  • 13
    • 0036196782 scopus 로고    scopus 로고
    • Short-circuiting long-lived humoral immunity by the heightened engagement of CD40
    • Erickson LD, Durell BG, Vogel LA, O'Connor BP, Cascalho M, et al. (2002) Short-circuiting long-lived humoral immunity by the heightened engagement of CD40. J Clin Invest 109: 613-620.
    • (2002) J Clin Invest , vol.109 , pp. 613-620
    • Erickson, L.D.1    Durell, B.G.2    Vogel, L.A.3    O'Connor, B.P.4    Cascalho, M.5
  • 14
    • 77956195961 scopus 로고    scopus 로고
    • Augmented Ab response with premature germinal center regression in CD40L transgenic mice
    • Kishi Y, Aiba Y, Higuchi T, Furukawa K, Tokuhisa T, et al. (2010) Augmented Ab response with premature germinal center regression in CD40L transgenic mice. J Immunol 185: 211-219.
    • (2010) J Immunol , vol.185 , pp. 211-219
    • Kishi, Y.1    Aiba, Y.2    Higuchi, T.3    Furukawa, K.4    Tokuhisa, T.5
  • 15
    • 77956196649 scopus 로고    scopus 로고
    • Constitutive CD40L expression on B cells prematurely terminates germinal center response and leads to augmented plasma cell production in T cell areas
    • Bolduc A, Long E, Stapler D, Cascalho M, Tsubata T, et al. (2010) Constitutive CD40L expression on B cells prematurely terminates germinal center response and leads to augmented plasma cell production in T cell areas. J Immunol 185: 220-230.
    • (2010) J Immunol , vol.185 , pp. 220-230
    • Bolduc, A.1    Long, E.2    Stapler, D.3    Cascalho, M.4    Tsubata, T.5
  • 16
    • 0031279986 scopus 로고    scopus 로고
    • CD40 ligand expressed on B cells in the BXSB mouse model of systemic lupus erythematosus
    • Blossom S, Chu EB, Weigle WO, Gilbert KM, (1997) CD40 ligand expressed on B cells in the BXSB mouse model of systemic lupus erythematosus. J Immunol 159: 4580-4586.
    • (1997) J Immunol , vol.159 , pp. 4580-4586
    • Blossom, S.1    Chu, E.B.2    Weigle, W.O.3    Gilbert, K.M.4
  • 17
    • 0029913381 scopus 로고    scopus 로고
    • Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production
    • Desai-Mehta A, Lu L, Ramsey-Goldman R, Datta SK, (1996) Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production. J Clin Invest 97: 2063-2073.
    • (1996) J Clin Invest , vol.97 , pp. 2063-2073
    • Desai-Mehta, A.1    Lu, L.2    Ramsey-Goldman, R.3    Datta, S.K.4
  • 18
    • 0345824714 scopus 로고    scopus 로고
    • Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions
    • Grammer AC, Slota R, Fischer R, Gur H, Girschick H, et al. (2003) Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions. J Clin Invest 112: 1506-1520.
    • (2003) J Clin Invest , vol.112 , pp. 1506-1520
    • Grammer, A.C.1    Slota, R.2    Fischer, R.3    Gur, H.4    Girschick, H.5
  • 19
    • 2442420974 scopus 로고    scopus 로고
    • Ectopic CD40 ligand expression on B cells triggers intestinal inflammation
    • Kawamura T, Kanai T, Dohi T, Uraushihara K, Totsuka T, et al. (2004) Ectopic CD40 ligand expression on B cells triggers intestinal inflammation. J Immunol 172: 6388-6397.
    • (2004) J Immunol , vol.172 , pp. 6388-6397
    • Kawamura, T.1    Kanai, T.2    Dohi, T.3    Uraushihara, K.4    Totsuka, T.5
  • 20
    • 0036134879 scopus 로고    scopus 로고
    • Cutting Edge: Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease
    • Higuchi T, Aiba Y, Nomura T, Matsuda J, Mochida K, et al. (2002) Cutting Edge: Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease. J Immunol 168: 9-12.
    • (2002) J Immunol , vol.168 , pp. 9-12
    • Higuchi, T.1    Aiba, Y.2    Nomura, T.3    Matsuda, J.4    Mochida, K.5
  • 21
    • 0029012969 scopus 로고
    • A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP
    • Doody GM, Justement LB, Delibrias CC, Mathews RJ, Lin J, et al. (1995) A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP. Science 269: 242-244.
    • (1995) Science , vol.269 , pp. 242-244
    • Doody, G.M.1    Justement, L.B.2    Delibrias, C.C.3    Mathews, R.J.4    Lin, J.5
  • 23
    • 0034625416 scopus 로고    scopus 로고
    • CD22 forms a quaternary complex with SHIP, Grb2 and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux
    • Poe JC, Fujimoto M, Jansen PJ, Miller AS, Tedder TF, (2000) CD22 forms a quaternary complex with SHIP, Grb2 and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux. J Biol Chem 275: 17420-17427.
    • (2000) J Biol Chem , vol.275 , pp. 17420-17427
    • Poe, J.C.1    Fujimoto, M.2    Jansen, P.J.3    Miller, A.S.4    Tedder, T.F.5
  • 24
    • 0030499431 scopus 로고    scopus 로고
    • CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice
    • Sato S, Miller AS, Inaoki M, Bock CB, Jansen PJ, et al. (1996) CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity 5: 551-562.
    • (1996) Immunity , vol.5 , pp. 551-562
    • Sato, S.1    Miller, A.S.2    Inaoki, M.3    Bock, C.B.4    Jansen, P.J.5
  • 25
    • 0842278644 scopus 로고    scopus 로고
    • Severely-impaired B lymphocyte proliferation, survival and induction of the c-Myc:Cullin 1 ubiquitin ligase pathway resulting from CD22 deficiency on the C57BL/6 genetic background
    • Poe JC, Haas KM, Uchida J, Lee Y, Fujimoto M, et al. (2004) Severely-impaired B lymphocyte proliferation, survival and induction of the c-Myc:Cullin 1 ubiquitin ligase pathway resulting from CD22 deficiency on the C57BL/6 genetic background. J Immunol 172: 2100-2110.
    • (2004) J Immunol , vol.172 , pp. 2100-2110
    • Poe, J.C.1    Haas, K.M.2    Uchida, J.3    Lee, Y.4    Fujimoto, M.5
  • 26
    • 75749087574 scopus 로고    scopus 로고
    • B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer
    • DiLillo DJ, Matsushita T, Tedder TF, (2010) B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer. Ann N Y Acad Sci 1183: 38-57.
    • (2010) Ann N Y Acad Sci , vol.1183 , pp. 38-57
    • DiLillo, D.J.1    Matsushita, T.2    Tedder, T.F.3
  • 27
    • 67649235672 scopus 로고    scopus 로고
    • The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals
    • Yanaba K, Bouaziz J-D, Matsushita T, Tsubata T, Tedder TF, (2009) The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals. J Immunol 182: 7459-7472.
    • (2009) J Immunol , vol.182 , pp. 7459-7472
    • Yanaba, K.1    Bouaziz, J.-D.2    Matsushita, T.3    Tsubata, T.4    Tedder, T.F.5
  • 28
    • 78751469622 scopus 로고    scopus 로고
    • Characterization of a rare IL-10-competent B cell subset in humans that parallels mouse regulatory B10 cells
    • Iwata Y, Matsushita T, Horikawa M, DiLillo DJ, Yanaba K, et al. (2011) Characterization of a rare IL-10-competent B cell subset in humans that parallels mouse regulatory B10 cells. Blood 117: 530-541.
    • (2011) Blood , vol.117 , pp. 530-541
    • Iwata, Y.1    Matsushita, T.2    Horikawa, M.3    DiLillo, D.J.4    Yanaba, K.5
  • 29
    • 0029924630 scopus 로고    scopus 로고
    • Frequent aberrant immunoglobulin gene rearrangements in pro-B cells revealed by a bcl-xL transgene
    • Fang W, Mueller DL, Pennell CA, Rivard JJ, Li YS, et al. (1996) Frequent aberrant immunoglobulin gene rearrangements in pro-B cells revealed by a bcl-xL transgene. Immunity 4: 291-299.
    • (1996) Immunity , vol.4 , pp. 291-299
    • Fang, W.1    Mueller, D.L.2    Pennell, C.A.3    Rivard, J.J.4    Li, Y.S.5
  • 30
    • 54949141219 scopus 로고    scopus 로고
    • Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression
    • Matsushita T, Yanaba K, Bouaziz J-D, Fujimoto M, Tedder TF, (2008) Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression. J Clin Invest 118: 3420-3430.
    • (2008) J Clin Invest , vol.118 , pp. 3420-3430
    • Matsushita, T.1    Yanaba, K.2    Bouaziz, J.-D.3    Fujimoto, M.4    Tedder, T.F.5
  • 31
    • 77956895769 scopus 로고    scopus 로고
    • Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling EAE initiation and late-phase immunopathogenesis
    • Matsushita T, Horikawa M, Iwata Y, Tedder TF, (2010) Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling EAE initiation and late-phase immunopathogenesis. J Immunol 185: 2240-2252.
    • (2010) J Immunol , vol.185 , pp. 2240-2252
    • Matsushita, T.1    Horikawa, M.2    Iwata, Y.3    Tedder, T.F.4
  • 32
    • 0029094609 scopus 로고
    • Abnormal B lymphocyte development, activation and differentiation in mice that lack or overexpress the CD19 signal transduction molecule
    • Engel P, Zhou L-J, Ord DC, Sato S, Koller B, et al. (1995) Abnormal B lymphocyte development, activation and differentiation in mice that lack or overexpress the CD19 signal transduction molecule. Immunity 3: 39-50.
    • (1995) Immunity , vol.3 , pp. 39-50
    • Engel, P.1    Zhou, L.-J.2    Ord, D.C.3    Sato, S.4    Koller, B.5
  • 33
    • 40449141768 scopus 로고    scopus 로고
    • Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice
    • DiLillo DJ, Hamaguchi Y, Ueda Y, Yang K, Uchida J, et al. (2008) Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice. J Immunol 180: 361-371.
    • (2008) J Immunol , vol.180 , pp. 361-371
    • DiLillo, D.J.1    Hamaguchi, Y.2    Ueda, Y.3    Yang, K.4    Uchida, J.5
  • 34
    • 33747752856 scopus 로고    scopus 로고
    • CD22 ligand binding regulates normal and malignant B lymphocyte survival in vivo
    • Haas KM, Sen S, Sanford IG, Miller AS, Poe JC, et al. (2006) CD22 ligand binding regulates normal and malignant B lymphocyte survival in vivo. J Immunol 177: 3063-3073.
    • (2006) J Immunol , vol.177 , pp. 3063-3073
    • Haas, K.M.1    Sen, S.2    Sanford, I.G.3    Miller, A.S.4    Poe, J.C.5
  • 35
    • 5444234832 scopus 로고    scopus 로고
    • CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms
    • Poe JC, Fujimoto Y, Hasegawa M, Haas KM, Miller AS, et al. (2004) CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms. Nat Immunol 5: 1078-1087.
    • (2004) Nat Immunol , vol.5 , pp. 1078-1087
    • Poe, J.C.1    Fujimoto, Y.2    Hasegawa, M.3    Haas, K.M.4    Miller, A.S.5
  • 36
    • 49249136452 scopus 로고    scopus 로고
    • Regulatory B cells as inhibitors of immune responses and inflammation
    • Bouaziz J-D, Yanaba K, Tedder TF, (2008) Regulatory B cells as inhibitors of immune responses and inflammation. Immunol Rev 224: 201-214.
    • (2008) Immunol Rev , vol.224 , pp. 201-214
    • Bouaziz, J.-D.1    Yanaba, K.2    Tedder, T.F.3
  • 37
    • 43049156086 scopus 로고    scopus 로고
    • A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses
    • Yanaba K, Bouaziz J-D, Haas KM, Poe JC, Fujimoto M, et al. (2008) A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses. Immunity 28: 639-650.
    • (2008) Immunity , vol.28 , pp. 639-650
    • Yanaba, K.1    Bouaziz, J.-D.2    Haas, K.M.3    Poe, J.C.4    Fujimoto, M.5
  • 38
    • 77954473511 scopus 로고    scopus 로고
    • Protective and pathogenic roles for B cells during systemic autoimmunity in NZB/W F1 mice
    • Haas KM, Watanabe R, Matsushita T, Nakashima H, Ishiura N, et al. (2010) Protective and pathogenic roles for B cells during systemic autoimmunity in NZB/W F1 mice. J Immunol 184: 4789-4800.
    • (2010) J Immunol , vol.184 , pp. 4789-4800
    • Haas, K.M.1    Watanabe, R.2    Matsushita, T.3    Nakashima, H.4    Ishiura, N.5
  • 39
    • 0030456897 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice
    • Wolf SD, Dittel BN, Hardardottir F, Janeway CA Jr, (1996) Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice. J Exp Med 184: 2271-2278.
    • (1996) J Exp Med , vol.184 , pp. 2271-2278
    • Wolf, S.D.1    Dittel, B.N.2    Hardardottir, F.3    Janeway Jr., C.A.4
  • 41
    • 42649124913 scopus 로고    scopus 로고
    • Not always the bad guys: B cells as regulators of autoimmune pathology
    • Fillatreau S, Gray D, Anderton SM, (2008) Not always the bad guys: B cells as regulators of autoimmune pathology. Nature Rev Immunol 8: 391-397.
    • (2008) Nature Rev Immunol , vol.8 , pp. 391-397
    • Fillatreau, S.1    Gray, D.2    Anderton, S.M.3
  • 42
    • 0036197923 scopus 로고    scopus 로고
    • Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation
    • Mizoguchi A, Mizoguchi E, Takedatsu H, Blumberg RS, Bhan AK, (2002) Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation. Immunity 16: 219-230.
    • (2002) Immunity , vol.16 , pp. 219-230
    • Mizoguchi, A.1    Mizoguchi, E.2    Takedatsu, H.3    Blumberg, R.S.4    Bhan, A.K.5
  • 43
    • 30544438882 scopus 로고    scopus 로고
    • To 'B' regulated: B cells as members of the regulatory workforce
    • Serra P, Santamaria P, (2006) To 'B' regulated: B cells as members of the regulatory workforce. Trends Immunol 27: 7-10.
    • (2006) Trends Immunol , vol.27 , pp. 7-10
    • Serra, P.1    Santamaria, P.2
  • 44
    • 37849044394 scopus 로고    scopus 로고
    • The 'short' history of regulatory B cells
    • Mauri C, Ehrenstein MR, (2008) The 'short' history of regulatory B cells. Trends Immunol 29: 34-40.
    • (2008) Trends Immunol , vol.29 , pp. 34-40
    • Mauri, C.1    Ehrenstein, M.R.2
  • 45
    • 45449099469 scopus 로고    scopus 로고
    • Cytokine-producing B lymphocytes-key regulators of immunity
    • Lund FE, (2008) Cytokine-producing B lymphocytes-key regulators of immunity. Curr Opin Immunol 20: 332-338.
    • (2008) Curr Opin Immunol , vol.20 , pp. 332-338
    • Lund, F.E.1
  • 46
    • 77954505663 scopus 로고    scopus 로고
    • Regulatory B cells (B10 cells) have a suppressive role in murine lupus: CD19 and B10 cell deficiency exacerbates systemic autoimmunity
    • Watanabe R, Ishiura N, Nakashima H, Kuwano Y, Okochi H, et al. (2010) Regulatory B cells (B10 cells) have a suppressive role in murine lupus: CD19 and B10 cell deficiency exacerbates systemic autoimmunity. J Immunol 184: 4801-4809.
    • (2010) J Immunol , vol.184 , pp. 4801-4809
    • Watanabe, R.1    Ishiura, N.2    Nakashima, H.3    Kuwano, Y.4    Okochi, H.5
  • 47
    • 1542514778 scopus 로고    scopus 로고
    • Distinct profiles of human B cell effector cytokines: a role in immune regulation
    • Duddy ME, Alter A, Bar-Or A, (2004) Distinct profiles of human B cell effector cytokines: a role in immune regulation. J Immunol 172: 3422-3427.
    • (2004) J Immunol , vol.172 , pp. 3422-3427
    • Duddy, M.E.1    Alter, A.2    Bar-Or, A.3
  • 48
    • 0037450740 scopus 로고    scopus 로고
    • Prevention of arthritis by interleukin 10-producing B cells
    • Mauri C, Gray D, Mushtaq N, Londei M, (2003) Prevention of arthritis by interleukin 10-producing B cells. J Exp Med 197: 489-501.
    • (2003) J Exp Med , vol.197 , pp. 489-501
    • Mauri, C.1    Gray, D.2    Mushtaq, N.3    Londei, M.4
  • 49
    • 0030666959 scopus 로고    scopus 로고
    • Suppressive role of B cells in chronic colitis of T cell receptor α mutant mice
    • Mizoguchi A, Mizoguchi E, Smith RN, Preffer FI, Bhan AK, (1997) Suppressive role of B cells in chronic colitis of T cell receptor α mutant mice. J Exp Med 186: 1749-1756.
    • (1997) J Exp Med , vol.186 , pp. 1749-1756
    • Mizoguchi, A.1    Mizoguchi, E.2    Smith, R.N.3    Preffer, F.I.4    Bhan, A.K.5
  • 50
    • 77955027018 scopus 로고    scopus 로고
    • B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals
    • Smith SH, Haas KM, Poe JC, Yanaba K, Ward CD, et al. (2010) B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals. Int Immunol 22: 681-691.
    • (2010) Int Immunol , vol.22 , pp. 681-691
    • Smith, S.H.1    Haas, K.M.2    Poe, J.C.3    Yanaba, K.4    Ward, C.D.5
  • 51
    • 0030272352 scopus 로고    scopus 로고
    • The many roles of CD40 in cell-mediated inflammatory responses
    • Stout RD, Suttles J, (1996) The many roles of CD40 in cell-mediated inflammatory responses. Immunol Today 17: 487-492.
    • (1996) Immunol Today , vol.17 , pp. 487-492
    • Stout, R.D.1    Suttles, J.2
  • 52
    • 67349266245 scopus 로고    scopus 로고
    • The co-evolution of our understanding of CD40 and inflammation
    • Wagner DH Jr, (2009) The co-evolution of our understanding of CD40 and inflammation. Diabetologia 52: 997-999.
    • (2009) Diabetologia , vol.52 , pp. 997-999
    • Wagner Jr., D.H.1
  • 53
    • 74649083783 scopus 로고    scopus 로고
    • CD19+CD24hiCD38hi B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients
    • Blair PA, Norena LY, Flores-Borja F, Rawlings DJ, Isenberg DA, et al. (2010) CD19+CD24hiCD38hi B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients. Immunity 32: 129-140.
    • (2010) Immunity , vol.32 , pp. 129-140
    • Blair, P.A.1    Norena, L.Y.2    Flores-Borja, F.3    Rawlings, D.J.4    Isenberg, D.A.5
  • 54
    • 0033583479 scopus 로고    scopus 로고
    • Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies
    • O'Keefe TL, Williams GT, Batista FD, Neuberger MS, (1999) Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies. J Exp Med 189: 1307-1313.
    • (1999) J Exp Med , vol.189 , pp. 1307-1313
    • O'Keefe, T.L.1    Williams, G.T.2    Batista, F.D.3    Neuberger, M.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.