Genetic polymorphisms modulate the folate metabolism of Brazilian individuals with Down syndrome

Molecular Biology Reports

Volumn 39, Issue 10, 2012, Pages 9277-9284

  Biselli, J M ^a   Zampieri, B L ^a   Goloni Bertollo, E M ^a   Haddad, R ^b   Fonseca, M F R ^b   Eberlin, M N ^b   Vannucchi, H ^c   Carvalho, V M ^d   Pavarino, E C ^a  

^a FACULDADE DE MEDICINA DE SÃO JOSÉ DO RIO PRETO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d Fleury   (Brazil)

Author keywords

Down syndrome; Folate; Genetic polymorphism; Homocysteine; Methylmalonic acid

Indexed keywords

BETAINE HOMOCYSTEINE METHYLTRANSFERASE; HOMOCYSTEINE; METHIONINE SYNTHASE REDUCTASE; METHYLENETETRAHYDROFOLATE DEHYDROGENASE; METHYLENETETRAHYDROFOLATE DEHYDROGENASE 1; METHYLMALONIC ACID; S ADENOSYLMETHIONINE; TRANSCOBALAMIN II; UNCLASSIFIED DRUG;

ADULT; AGE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN SYNDROME; FEMALE; FOLATE METABOLISM; FOLIC ACID BLOOD LEVEL; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; IMMUNOASSAY; INFANT; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TANDEM MASS SPECTROMETRY;

ADOLESCENT; ADULT; BRAZIL; CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, PAIR 21; DOWN SYNDROME; FEMALE; FOLIC ACID; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENOTYPE; HOMOCYSTEINE; HUMANS; INFANT; LINEAR MODELS; MALE; METHYLMALONIC ACID; POLYMORPHISM, GENETIC; SEQUENCE ANALYSIS, DNA; VITAMIN B 12 DEFICIENCY; YOUNG ADULT;

EID: 84868595660     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-1629-5     Document Type: Article

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