-
1
-
-
0024342063
-
Plasma homocysteine, a risk factor for vascular disease: Plasma levels in health, disease, and drug therapy
-
Ueland, P. M. and Refsum, H. (1989) Plasma homocysteine, a risk factor for vascular disease: plasma levels in health, disease, and drug therapy. J. Lab. Clin. Med. 114, 473-501.
-
(1989)
J. Lab. Clin. Med.
, vol.114
, pp. 473-501
-
-
Ueland, P.M.1
Refsum, H.2
-
2
-
-
0034672509
-
Betaine-homocysteine methyltransferase-2: cDNA cloning, gene sequence, physical map-ping, and expression of the human and mouse genes
-
Chadwick, L. H., McCandless, S. E., Silverman, G. L., Schwartz, S., Westaway, D. and Nadeau, J. H. (2000) Betaine-homocysteine methyltransferase-2: cDNA cloning, gene sequence, physical map-ping, and expression of the human and mouse genes. Genomics 70, 66-73.
-
(2000)
Genomics
, vol.70
, pp. 66-73
-
-
Chadwick, L.H.1
McCandless, S.E.2
Silverman, G.L.3
Schwartz, S.4
Westaway, D.5
Nadeau, J.H.6
-
3
-
-
0037458623
-
Plasma homocysteine is regulated by phospholipid methylation
-
Noga, A. A., Stead, L. M., Zhao, Y., Brosnan, M. E., Brosnan, J. T. and Vance, D. E. (2003) Plasma homocysteine is regulated by phospholipid methylation. J. Biol. Chem. 278, 5952-5955.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5952-5955
-
-
Noga, A.A.1
Stead, L.M.2
Zhao, Y.3
Brosnan, M.E.4
Brosnan, J.T.5
Vance, D.E.6
-
4
-
-
3242795763
-
Methylation demand: A key determinant of homocysteine metabolism
-
Brosnan, J. T., Jacobs, R. L., Stead, L. M. and Brosnan, M. E. (2004) Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim. Pol. 51, 405-413.
-
(2004)
Acta Biochim. Pol.
, vol.51
, pp. 405-413
-
-
Brosnan, J.T.1
Jacobs, R.L.2
Stead, L.M.3
Brosnan, M.E.4
-
5
-
-
0024351118
-
Fasting plasma homocysteine as a sensitive parameter of antifolate effect: A study of psoriasis patients receiving low-dose methotrexate treatment
-
Refsum, H., Helland, S. and Ueland, P. M. (1989) Fasting plasma homocysteine as a sensitive parameter of antifolate effect: a study of psoriasis patients receiving low-dose methotrexate treatment. Clin. Pharmacol. Ther. 46, 510-520.
-
(1989)
Clin. Pharmacol. Ther.
, vol.46
, pp. 510-520
-
-
Refsum, H.1
Helland, S.2
Ueland, P.M.3
-
6
-
-
0030920140
-
S-adenosylmethionine synthesis: Molecular mechanisms and clinical implications
-
Mato, J. M., Alvarez, L., Ortiz, P. and Pajares, M. A. (1987) S-adenosylmethionine synthesis: molecular mechanisms and clinical implications. Pharmacol. Ther. 73, 265-280.
-
(1987)
Pharmacol. Ther.
, vol.73
, pp. 265-280
-
-
Mato, J.M.1
Alvarez, L.2
Ortiz, P.3
Pajares, M.A.4
-
7
-
-
0031737909
-
Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat
-
Jacobs, R. L., House, J. D., Brosnan, M. E. and Brosnan, J. T. (1998) Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat. Diabetes 47, 1967-1970.
-
(1998)
Diabetes
, vol.47
, pp. 1967-1970
-
-
Jacobs, R.L.1
House, J.D.2
Brosnan, M.E.3
Brosnan, J.T.4
-
8
-
-
0029787429
-
Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase
-
Garrow, T. A. (1996) Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase. J. Biol. Chem. 271, 22831-22838.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22831-22838
-
-
Garrow, T.A.1
-
9
-
-
0021220516
-
Methionine metabolism in mammals: Distribution of homocysteine between competing pathways
-
Finkelstein, J. D. and Martin, J. J. (1984) Methionine metabolism in mammals: distribution of homocysteine between competing pathways. J. Biol. Chem. 259, 9508-9513.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 9508-9513
-
-
Finkelstein, J.D.1
Martin, J.J.2
-
10
-
-
4544358286
-
Betaine in human nutrition
-
Craig, S. A. (2004) Betaine in human nutrition. Am. J. Clin. Nutr. 80, 539-546.
-
(2004)
Am. J. Clin. Nutr.
, vol.80
, pp. 539-546
-
-
Craig, S.A.1
-
11
-
-
0025934347
-
Renal medullary organic osmolytes
-
García-Pérez, A. and Burg, M. B. (1991) Renal medullary organic osmolytes. Physiol. Rev. 71, 1081-1115.
-
(1991)
Physiol. Rev.
, vol.71
, pp. 1081-1115
-
-
García-Pérez, A.1
Burg, M.B.2
-
12
-
-
0019203791
-
Uptake of free choline by isolated perfused rat liver
-
Zeisel, S. H., Story, D. L., Wurtman, R. J. and Brunengraber, H. (1980) Uptake of free choline by isolated perfused rat liver. Proc. Natl. Acad. Sci. USA 77, 4417-4419.
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 4417-4419
-
-
Zeisel, S.H.1
Story, D.L.2
Wurtman, R.J.3
Brunengraber, H.4
-
13
-
-
0027528821
-
Characterization of betaine efflux from rat liver mitochondria
-
Porter, R. K., Scott, J. M. and Brand, M. D. (1993) Characterization of betaine efflux from rat liver mitochondria. Biochim. Biophys. Acta 1141, 269-274.
-
(1993)
Biochim. Biophys. Acta
, vol.1141
, pp. 269-274
-
-
Porter, R.K.1
Scott, J.M.2
Brand, M.D.3
-
14
-
-
0000749205
-
The function of cytidine coenzymes in the biosynthesis of phospholipids
-
Kennedy, E. G. and Weiss, S. B. (1956) The function of cytidine coenzymes in the biosynthesis of phospholipids. J. Biol. Chem. 222, 193-214.
-
(1956)
J. Biol. Chem.
, vol.222
, pp. 193-214
-
-
Kennedy, E.G.1
Weiss, S.B.2
-
15
-
-
0003196818
-
Mono and dimethylethanolamine isolated from rat liver phospholipids
-
Bremer, J. and Greenberg, D. M. (1959) Mono and dimethylethanolamine isolated from rat liver phospholipids. Biochim. Biophys. Acta 37, 173-175.
-
(1959)
Biochim. Biophys. Acta
, vol.37
, pp. 173-175
-
-
Bremer, J.1
Greenberg, D.M.2
-
16
-
-
0016761879
-
Regulation of phospholipid biosynthesis in isolated rat hepatocytes
-
Sundler, R. and Akesson, B. (1975) Regulation of phospholipid biosynthesis in isolated rat hepatocytes. J. Biol. Chem. 250, 3359-3367.
-
(1975)
J. Biol. Chem.
, vol.250
, pp. 3359-3367
-
-
Sundler, R.1
Akesson, B.2
-
17
-
-
0026710639
-
Choline transport into rat liver mitochondria: Characterization and kinetics of a specific transporter
-
Porter, R. K., Scott, J. M. and Brand, M. D. (1992) Choline transport into rat liver mitochondria: characterization and kinetics of a specific transporter. J. Biol. Chem. 26, 14637-14646.
-
(1992)
J. Biol. Chem.
, vol.26
, pp. 14637-14646
-
-
Porter, R.K.1
Scott, J.M.2
Brand, M.D.3
-
18
-
-
0033583210
-
Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene
-
Park, E. I. and Garrow, T. A. (1999) Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene. J. Biol. Chem. 274, 7816-7824.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7816-7824
-
-
Park, E.I.1
Garrow, T.A.2
-
19
-
-
0034733006
-
Isolation and characterization of a mouse betaine-homocysteine S-methyltransferase gene and pseudogene
-
Neece, D. J., Griffiths, M. A. and Garrow, T. A. (2000) Isolation and characterization of a mouse betaine-homocysteine S-methyltransferase gene and pseudogene. Gene 250, 31-40.
-
(2000)
Gene
, vol.250
, pp. 31-40
-
-
Neece, D.J.1
Griffiths, M.A.2
Garrow, T.A.3
-
20
-
-
0031239784
-
Betaine-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene
-
Sunden, S. L., Renduchintala, M. S., Park, E. I., Miklasz, S. D. and Garrow, T. A. (1997) Betaine-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene. Arch. Biochem. Biophys. 345, 171-174.
-
(1997)
Arch. Biochem. Biophys.
, vol.345
, pp. 171-174
-
-
Sunden, S.L.1
Renduchintala, M.S.2
Park, E.I.3
Miklasz, S.D.4
Garrow, T.A.5
-
21
-
-
33646792817
-
Betaine-homocysteine S-methyltransferase (BHMT) transcription is inhibited by S-adenosylmethionine (AdoMet)
-
(Milstien, S., Kapatos, G., Levine, R. A. and Shane, B. Eds), Kluwer, Norwell
-
Castro, C., Breksa, A. P. III, Salisbury, E. M. and Garrow, T. A. (2001) Betaine-homocysteine S-methyltransferase (BHMT) transcription is inhibited by S-adenosylmethionine (AdoMet). In: Chemistry and Biology of Pteridines and Folates (Milstien, S., Kapatos, G., Levine, R. A. and Shane, B. Eds), pp. 549-556. Kluwer, Norwell.
-
(2001)
Chemistry and Biology of Pteridines and Folates
, pp. 549-556
-
-
Castro, C.1
Breksa III, A.P.2
Salisbury, E.M.3
Garrow, T.A.4
-
22
-
-
0026045338
-
Betaine-homocysteine methyltransferase: Organ distribution in man, pig and rat and subcellular distribution in the rat
-
McKeever, M. P., Weir, D. G., Molloy, A. and Scott, J. M. (1991) Betaine-homocysteine methyltransferase: organ distribution in man, pig and rat and subcellular distribution in the rat. Clin. Sci. 81, 551-556.
-
(1991)
Clin. Sci.
, vol.81
, pp. 551-556
-
-
McKeever, M.P.1
Weir, D.G.2
Molloy, A.3
Scott, J.M.4
-
23
-
-
0018595238
-
Betaine-homocysteine methyltransferase in the fungus Aspergillus nidulans
-
Balinska, M. and Paszewski, A. (1979) Betaine-homocysteine methyltransferase in the fungus Aspergillus nidulans. Biochem. Biophys. Res. Commun. 91, 1095-1100.
-
(1979)
Biochem. Biophys. Res. Commun.
, vol.91
, pp. 1095-1100
-
-
Balinska, M.1
Paszewski, A.2
-
24
-
-
0034957644
-
Purification and kinetic properties of betaine-homocysteine methyltransferase from Aphanothece halophytica
-
Waditee, R. and Incharoensakdi, A. (2001) Purification and kinetic properties of betaine-homocysteine methyltransferase from Aphanothece halophytica. Curr. Microbiol. 43, 107-111.
-
(2001)
Curr. Microbiol.
, vol.43
, pp. 107-111
-
-
Waditee, R.1
Incharoensakdi, A.2
-
25
-
-
0036549286
-
Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro
-
Fisher, M. C., Zeisel, S. H., Mar, M. H. and Sadler, T. W. (2002) Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro. FASEB J. 16, 619-621.
-
(2002)
FASEB J.
, vol.16
, pp. 619-621
-
-
Fisher, M.C.1
Zeisel, S.H.2
Mar, M.H.3
Sadler, T.W.4
-
26
-
-
0034607113
-
Comprehesive gene expression profile of a normal human liver
-
Yamashita, T., Hashimoto, S., Kaneko, S., Nagai, S., Toyoda, N., Suzuki, T., Kobayashi, K. and Matsushima, K. (2000) Comprehesive gene expression profile of a normal human liver. Biochem. Biophys. Res. Commun. 269, 110-116.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.269
, pp. 110-116
-
-
Yamashita, T.1
Hashimoto, S.2
Kaneko, S.3
Nagai, S.4
Toyoda, N.5
Suzuki, T.6
Kobayashi, K.7
Matsushima, K.8
-
27
-
-
0019462611
-
Enzymatic determination of betaine in rat tissues
-
Martin, J. J. and Finkelstein, J. D. (1981) Enzymatic determination of betaine in rat tissues. Anal. Biochem. 111, 72-76.
-
(1981)
Anal. Biochem.
, vol.111
, pp. 72-76
-
-
Martin, J.J.1
Finkelstein, J.D.2
-
28
-
-
0022596611
-
Developmental changes in the activities of enzymes related to methyl group metabolism in sheep tissues
-
Xue, G. P. and Snoswell, A. M. (1986) Developmental changes in the activities of enzymes related to methyl group metabolism in sheep tissues. Comp. Biochem. Physiol. 83B, 115-120.
-
(1986)
Comp. Biochem. Physiol.
, vol.83 B
, pp. 115-120
-
-
Xue, G.P.1
Snoswell, A.M.2
-
29
-
-
0032514889
-
Betaine-homocysteine methyltransferase is a developmentally regulated enzyme crystallin in rhesus monkey lens
-
Rao, P. V., Garrow, T. A., John, F., Garland, D., Millian, N. S. and Zigler, J. S. Jr (1998) Betaine-homocysteine methyltransferase is a developmentally regulated enzyme crystallin in rhesus monkey lens. J. Biol. Chem. 273, 30669-30674.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 30669-30674
-
-
Rao, P.V.1
Garrow, T.A.2
John, F.3
Garland, D.4
Millian, N.S.5
Zigler Jr., J.S.6
-
30
-
-
0020491455
-
Human hepatic methionine biosynthesis: Purification and characterization of betaine:Homocysteine S-methyltransferase
-
Skiba, W. E., Taylor, M. P., Wells, M. S., Mangum, J. H. and Awad, W. M. Jr (1982) Human hepatic methionine biosynthesis: purification and characterization of betaine:homocysteine S-methyltransferase. J. Biol. Chem. 257, 14944-14948.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 14944-14948
-
-
Skiba, W.E.1
Taylor, M.P.2
Wells, M.S.3
Mangum, J.H.4
Awad Jr., W.M.5
-
31
-
-
0027198477
-
Disordered methionine/homocysteine metabolism in premature vascular disease: Its occurrence, cofactor therapy, and enzymology
-
Dudman, N. P., Wilcken, D. E., Wang, J., Lynch, J. F., Macey, D. and Lundberg, P. (1993) Disordered methionine/homocysteine metabolism in premature vascular disease: its occurrence, cofactor therapy, and enzymology. Arterioscler. Thromb. 13, 1253-1260.
-
(1993)
Arterioscler. Thromb.
, vol.13
, pp. 1253-1260
-
-
Dudman, N.P.1
Wilcken, D.E.2
Wang, J.3
Lynch, J.F.4
Macey, D.5
Lundberg, P.6
-
32
-
-
0035450414
-
Immunohistochemical detection of betaine-homocysteine S-methyltransferase in human, pig, and rat liver and kidney
-
Delgado-Reyes, C. V., Wallig, M. A. and Garrow, T. A. (2001) Immunohistochemical detection of betaine-homocysteine S-methyltransferase in human, pig, and rat liver and kidney. Arch. Biochem. Biophys. 393, 184-186.
-
(2001)
Arch. Biochem. Biophys.
, vol.393
, pp. 184-186
-
-
Delgado-Reyes, C.V.1
Wallig, M.A.2
Garrow, T.A.3
-
33
-
-
12444341903
-
Localization of the PE methylation pathway and SR-BI to the canalicular membrane: Evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol
-
Sehayek, E., Wang, R., Ono, J. G., Zinchuk, V. S., Duncan, E. M., Shefer, S., Vance, D. E., Ananthanarayanan, M., Chait, B. T. and Breslow, J. L. (2003) Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol. J. Lipid Res. 44, 1605-1613.
-
(2003)
J. Lipid Res.
, vol.44
, pp. 1605-1613
-
-
Sehayek, E.1
Wang, R.2
Ono, J.G.3
Zinchuk, V.S.4
Duncan, E.M.5
Shefer, S.6
Vance, D.E.7
Ananthanarayanan, M.8
Chait, B.T.9
Breslow, J.L.10
-
34
-
-
0015427721
-
Methionine metabolism in mammals: Kinetic study of betaine-homocysteine methyltransferase
-
Finkelstein, J. D., Harris, B. J. and Kyle, W. E. (1972) Methionine metabolism in mammals: kinetic study of betaine-homocysteine methyltransferase. Arch. Biochem. Biophys. 153, 320-324.
-
(1972)
Arch. Biochem. Biophys.
, vol.153
, pp. 320-324
-
-
Finkelstein, J.D.1
Harris, B.J.2
Kyle, W.E.3
-
35
-
-
0026593201
-
Betaine: Homocysteine methyltransferase from rat liver: Purification and inhibition by a boronic acid substrate analog
-
Lee, K. H., Cava, M., Amiri, P., Ottoboni, T. and Lindquist, R. N. (1992) Betaine: homocysteine methyltransferase from rat liver: purification and inhibition by a boronic acid substrate analog. Arch. Biochem. Biophys. 292, 77-86.
-
(1992)
Arch. Biochem. Biophys.
, vol.292
, pp. 77-86
-
-
Lee, K.H.1
Cava, M.2
Amiri, P.3
Ottoboni, T.4
Lindquist, R.N.5
-
36
-
-
0035098121
-
Crystallization and preliminary X-ray crystallographic studies of recombinant human betaine-homocysteine S-methyltransferase
-
Bose, N. and Momany, C. (2001) Crystallization and preliminary X-ray crystallographic studies of recombinant human betaine-homocysteine S-methyltransferase. Acta Crystallogr. D Biol. Crystallogr. 57, 431-433.
-
(2001)
Acta Crystallogr. D Biol. Crystallogr.
, vol.57
, pp. 431-433
-
-
Bose, N.1
Momany, C.2
-
37
-
-
0036713122
-
Crystallization and preliminary X-ray study of recombinant betaine-homocysteine S-methyltransferase from rat liver
-
González, B., Pajares, M. A., Too, H. P., Garrido, F., Blundell, T. L. and Sanz-Aparicio, J. (2002) Crystallization and preliminary X-ray study of recombinant betaine-homocysteine S-methyltransferase from rat liver. Acta Crystallogr. D Biol. Crystallogr. 58, 1507-1510.
-
(2002)
Acta Crystallogr. D Biol. Crystallogr.
, vol.58
, pp. 1507-1510
-
-
González, B.1
Pajares, M.A.2
Too, H.P.3
Garrido, F.4
Blundell, T.L.5
Sanz-Aparicio, J.6
-
38
-
-
0036711477
-
Betaine-homocysteine methyltransferase: Zinc in a distorted barrel
-
Evans, J. C., Huddler, D. P., Jiracek, J., Castro, C., Millian, N. S., Garrow, T. A. and Ludwig, M. L. (2002) Betaine-homocysteine methyltransferase: zinc in a distorted barrel. Structure 10, 1159-1171.
-
(2002)
Structure
, vol.10
, pp. 1159-1171
-
-
Evans, J.C.1
Huddler, D.P.2
Jiracek, J.3
Castro, C.4
Millian, N.S.5
Garrow, T.A.6
Ludwig, M.L.7
-
39
-
-
2442603566
-
Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis
-
Castro, C., Gratson, A. A., Evans, J. C., Jiracek, J., Collinsova, M., Ludwig, M. L. and Garrow, T. A. (2004) Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis. Biochemistry 43, 5341-5351.
-
(2004)
Biochemistry
, vol.43
, pp. 5341-5351
-
-
Castro, C.1
Gratson, A.A.2
Evans, J.C.3
Jiracek, J.4
Collinsova, M.5
Ludwig, M.L.6
Garrow, T.A.7
-
40
-
-
0032147170
-
Human betaine-homocysteine methyltransferase is a zinc metalloenzyme
-
Millian, N. S. and Garrow, T. A. (1998) Human betaine-homocysteine methyltransferase is a zinc metalloenzyme. Arch. Biochem. Biophys. 356, 93-98.
-
(1998)
Arch. Biochem. Biophys.
, vol.356
, pp. 93-98
-
-
Millian, N.S.1
Garrow, T.A.2
-
41
-
-
0037444810
-
Active-site mutagenesis study of rat liver betaine-homocysteine S-methyltransferase
-
Gonzalez, B., Campillo, N., Garrido, F., Gasset, M., Sanz-Aparicio, J. and Pajares, M. A. (2003) Active-site mutagenesis study of rat liver betaine-homocysteine S-methyltransferase. Biochem. J. 370, 945-952.
-
(2003)
Biochem. J.
, vol.370
, pp. 945-952
-
-
Gonzalez, B.1
Campillo, N.2
Garrido, F.3
Gasset, M.4
Sanz-Aparicio, J.5
Pajares, M.A.6
-
42
-
-
0016371704
-
Methionine metabolism in mammals: Regulatory effects of S-adenosylhomocysteine
-
Finkelstein, J. D., Kyle, W. E. and Harris, B. J. (1974) Methionine metabolism in mammals: regulatory effects of S-adenosylhomocysteine. Arch. Biochem. Biophys. 165, 774-779.
-
(1974)
Arch. Biochem. Biophys.
, vol.165
, pp. 774-779
-
-
Finkelstein, J.D.1
Kyle, W.E.2
Harris, B.J.3
-
43
-
-
0021100297
-
Evidence for direct methyl transfer in betaine: Homocysteine methyltransferase
-
Awad, W. M. Jr, Whitney, P. L., Skiba, W. E., Mangum, J. H. and Wells, M. S. (1983) Evidence for direct methyl transfer in betaine: homocysteine methyltransferase. J. Biol. Chem. 258, 12790-12792.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 12790-12792
-
-
Awad Jr., W.M.1
Whitney, P.L.2
Skiba, W.E.3
Mangum, J.H.4
Wells, M.S.5
-
44
-
-
0021761430
-
Inactivation of betaine-homocysteine methyltransferase by adenosylmethionine and adenosylethionine
-
Finkelstein, J. D. and Martin, J. J. (1984) Inactivation of betaine-homocysteine methyltransferase by adenosylmethionine and adenosylethionine. Biochem. Biophys. Res. Commun. 118, 14-19.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.118
, pp. 14-19
-
-
Finkelstein, J.D.1
Martin, J.J.2
-
45
-
-
0037330285
-
Combining combinatorial chemistry and affinity chromatography: Highly selective inhibitors of human betaine:Homocysteine S-methyltransferase
-
Collinsova, M., Castro, C., Garrow, T. A., Yiotakis, A., Dive, V. and Jiracek, J. (2003) Combining combinatorial chemistry and affinity chromatography: highly selective inhibitors of human betaine:homocysteine S-methyltransferase. Chem. Biol. 10, 113-122.
-
(2003)
Chem. Biol.
, vol.10
, pp. 113-122
-
-
Collinsova, M.1
Castro, C.2
Garrow, T.A.3
Yiotakis, A.4
Dive, V.5
Jiracek, J.6
-
46
-
-
0027515431
-
Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism
-
Allen, R. H., Stabler, S. P. and Lindenbaum, J. (1993) Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism. Metabolism 42, 1448-1460.
-
(1993)
Metabolism
, vol.42
, pp. 1448-1460
-
-
Allen, R.H.1
Stabler, S.P.2
Lindenbaum, J.3
-
47
-
-
33745662826
-
S-alkylated homocysteine derivatives: New inhibitors of human betaine-homocysteine S-methyltransferase
-
Jiracek, J., Collinsova, M., Rosenberg, I., Budesinsky, M., Protivinska, E., Netusilova, H. and Garrow, T. A. (2006) S-alkylated homocysteine derivatives: new inhibitors of human betaine-homocysteine S-methyltransferase. J. Med. Chem. 49, 3982-3989.
-
(2006)
J. Med. Chem.
, vol.49
, pp. 3982-3989
-
-
Jiracek, J.1
Collinsova, M.2
Rosenberg, I.3
Budesinsky, M.4
Protivinska, E.5
Netusilova, H.6
Garrow, T.A.7
-
48
-
-
0345624497
-
Recombinant human liver betaine-homocysteine S-methyltransferase: Identification of three cysteine residues critical for zinc binding
-
rd and Garrow, T. A. (1999) Recombinant human liver betaine-homocysteine S-methyltransferase: identification of three cysteine residues critical for zinc binding. Biochemistry 38, 13991-13998.
-
(1999)
Biochemistry
, vol.38
, pp. 13991-13998
-
-
Breksa III, A.P.1
Garrow, T.A.2
-
49
-
-
1942457281
-
Crystal structure of rat liver betaine homocysteine s-methyltransferase reveals new oligomerization features and conformational changes upon substrate binding
-
Gonzalez, B., Pajares, M. A., Martínez-Ripoll, M., Blundell, T. L. and Sanz-Aparicio, J. (2004) Crystal structure of rat liver betaine homocysteine s-methyltransferase reveals new oligomerization features and conformational changes upon substrate binding. J. Mol. Biol. 338, 771-782.
-
(2004)
J. Mol. Biol.
, vol.338
, pp. 771-782
-
-
Gonzalez, B.1
Pajares, M.A.2
Martínez-Ripoll, M.3
Blundell, T.L.4
Sanz-Aparicio, J.5
-
50
-
-
0036509518
-
Random mutagenesis of the zinc-binding motif of betaine-homocysteine methyltransferase reveals that Gly 214 is essential
-
Breksa, A. P. 3rd and Garrow, T. A. (2002) Random mutagenesis of the zinc-binding motif of betaine-homocysteine methyltransferase reveals that Gly 214 is essential. Arch. Biochem. Biophys. 399, 73-80.
-
(2002)
Arch. Biochem. Biophys.
, vol.399
, pp. 73-80
-
-
Breksa III, A.P.1
Garrow, T.A.2
-
51
-
-
29644433420
-
Conformation-dependent inactivation of human betaine-homocysteine S-methyltransferase by hydrogen peroxide in vitro
-
Miller, C. M., Szegedi, S. S. and Garrow, T. A. (2005) Conformation-dependent inactivation of human betaine-homocysteine S-methyltransferase by hydrogen peroxide in vitro. Biochem. J. 392, 443-448.
-
(2005)
Biochem. J.
, vol.392
, pp. 443-448
-
-
Miller, C.M.1
Szegedi, S.S.2
Garrow, T.A.3
-
52
-
-
2342498275
-
Oligomerization is required for betaine-homocysteine S-methyltransferase function
-
Szegedi, S. S. and Garrow, T. A. (2004) Oligomerization is required for betaine-homocysteine S-methyltransferase function. Arch. Biochem. Biophys. 426, 32-42.
-
(2004)
Arch. Biochem. Biophys.
, vol.426
, pp. 32-42
-
-
Szegedi, S.S.1
Garrow, T.A.2
-
53
-
-
27744488576
-
Rat liver betaine-homocysteine S-methyltransferase equilibrium unfolding: Insights into intermediate structure through tryptophan substitutions
-
Garrido, F., Gasset, M., Sanz-Aparicio, J., Alfons, C. and Pajares, M. A. (2005) Rat liver betaine-homocysteine S-methyltransferase equilibrium unfolding: insights into intermediate structure through tryptophan substitutions. Biochem. J. 391, 589-599.
-
(2005)
Biochem. J.
, vol.391
, pp. 589-599
-
-
Garrido, F.1
Gasset, M.2
Sanz-Aparicio, J.3
Alfons, C.4
Pajares, M.A.5
-
54
-
-
0033179315
-
Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase
-
Sowden, M. P., Collins, H. L., Smith, H. C., Garrow, T. A., Sparks, J. D. and Sparks, C. E. (1999) Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase. Biochem. J. 341, 639-645.
-
(1999)
Biochem. J.
, vol.341
, pp. 639-645
-
-
Sowden, M.P.1
Collins, H.L.2
Smith, H.C.3
Garrow, T.A.4
Sparks, J.D.5
Sparks, C.E.6
-
55
-
-
0024653550
-
Effect of vitamin B12-deficien-cy on the activity of hepatic cystathionine beta-synthase in rats
-
Doi, T., Kawata, T., Tadano, N., Iijima, T. and Maekawa, A. (1989) Effect of vitamin B12-deficien-cy on the activity of hepatic cystathionine beta-synthase in rats. J. Nutr. Sci. Vitaminol. 35, 101-110.
-
(1989)
J. Nutr. Sci. Vitaminol.
, vol.35
, pp. 101-110
-
-
Doi, T.1
Kawata, T.2
Tadano, N.3
Iijima, T.4
Maekawa, A.5
-
56
-
-
0020615293
-
Regulation of hepatic betaine-homocysteine methyltransferase by dietary betaine
-
Finkelstein, J. D., Martin, J. J., Harris, B. J. and Kyle, W. E. (1983) Regulation of hepatic betaine-homocysteine methyltransferase by dietary betaine. J. Nutr. 113, 519-521.
-
(1983)
J. Nutr.
, vol.113
, pp. 519-521
-
-
Finkelstein, J.D.1
Martin, J.J.2
Harris, B.J.3
Kyle, W.E.4
-
57
-
-
0023032002
-
Methionine metabolism in mammals: Adaptation to methionine excess
-
Finkelstein, J. D. and Martin, J. J. (1986) Methionine metabolism in mammals: adaptation to methionine excess. J. Biol. Chem. 261, 1582-1587.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 1582-1587
-
-
Finkelstein, J.D.1
Martin, J.J.2
-
58
-
-
0022480508
-
Effect of dietary cystine on methionine metabolism in rat liver
-
Finkelstein, J. D., Martin, J. J. and Harris, B. J. (1986) Effect of dietary cystine on methionine metabolism in rat liver. J. Nutr. 116, 985-990.
-
(1986)
J. Nutr.
, vol.116
, pp. 985-990
-
-
Finkelstein, J.D.1
Martin, J.J.2
Harris, B.J.3
-
59
-
-
0023732986
-
Methionine metabolism in mammals: The methionine-sparing effect of cystine
-
Finkelstein, J. D., Martin, J. J. and Harris, B. J. (1988) Methionine metabolism in mammals: the methionine-sparing effect of cystine. J. Biol. Chem. 263, 11750-11754.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 11750-11754
-
-
Finkelstein, J.D.1
Martin, J.J.2
Harris, B.J.3
-
60
-
-
0036273776
-
Selenium deficiency in Fisher-344 rats decreases plasma and tissue homocysteine concentrations and alters plasma homocysteine and cysteine redox status
-
Uthus, E. O., Yokoi, K. and Davis, C. D. (2002) Selenium deficiency in Fisher-344 rats decreases plasma and tissue homocysteine concentrations and alters plasma homocysteine and cysteine redox status. J. Nutr. 132, 1122-1128.
-
(2002)
J. Nutr.
, vol.132
, pp. 1122-1128
-
-
Uthus, E.O.1
Yokoi, K.2
Davis, C.D.3
-
61
-
-
0041417403
-
Dietary folate and selenium affect dimethylhydrazine-induced aberrant crypt formation, global DNA methylation and one-carbon metabolism in rats
-
Davis, C. D. and Uthus, E. O. (2003) Dietary folate and selenium affect dimethylhydrazine-induced aberrant crypt formation, global DNA methylation and one-carbon metabolism in rats. J. Nutr. 133, 2907-2914.
-
(2003)
J. Nutr.
, vol.133
, pp. 2907-2914
-
-
Davis, C.D.1
Uthus, E.O.2
-
62
-
-
0017951821
-
The effect of diet and of methionine loading on activity of enzymes in the transulfuration pathway in sheep
-
Radcliffe, B. C. and Egan, A. R. (1978) The effect of diet and of methionine loading on activity of enzymes in the transulfuration pathway in sheep. Aust. J. Biol. Sci. 31, 105-114.
-
(1978)
Aust. J. Biol. Sci.
, vol.31
, pp. 105-114
-
-
Radcliffe, B.C.1
Egan, A.R.2
-
63
-
-
0031989155
-
Hepatic and renal betaine-homocysteine methyltransferase activity in pigs as affected by dietary intakes of sulfur amino acids, choline, and betaine
-
Emmert, J. L., Webel, D. M., Biehl, R. R., Griffiths, M. A., Garrow, L. S., Garrow, T. A. and Baker, D. H. (1998) Hepatic and renal betaine-homocysteine methyltransferase activity in pigs as affected by dietary intakes of sulfur amino acids, choline, and betaine. J. Anim. Sci. 76, 606-610.
-
(1998)
J. Anim. Sci.
, vol.76
, pp. 606-610
-
-
Emmert, J.L.1
Webel, D.M.2
Biehl, R.R.3
Griffiths, M.A.4
Garrow, L.S.5
Garrow, T.A.6
Baker, D.H.7
-
64
-
-
0014034924
-
The effect of alcoholism on absorption of folic acid (H3-PGA) evaluated by plasma levels and urine excretion
-
Halsted, C. H., Griggs, R. C. and Harris, J. W. (1967) The effect of alcoholism on absorption of folic acid (H3-PGA) evaluated by plasma levels and urine excretion. J. Lab. Clin. Med. 69, 116-131.
-
(1967)
J. Lab. Clin. Med.
, vol.69
, pp. 116-131
-
-
Halsted, C.H.1
Griggs, R.C.2
Harris, J.W.3
-
65
-
-
0016209349
-
Ethanol-induced changes in methionine metabolism in rat liver
-
Finkelstein, J. D., Cello, J. P. and Kyle, W. E. (1974) Ethanol-induced changes in methionine metabolism in rat liver. Biochem. Biophys. Res. Commun. 61, 525-531.
-
(1974)
Biochem. Biophys. Res. Commun.
, vol.61
, pp. 525-531
-
-
Finkelstein, J.D.1
Cello, J.P.2
Kyle, W.E.3
-
66
-
-
0030248641
-
Betaine effects on hepatic methionine metabolism elicited by short-term ethanol feeding
-
Barak, A. J., Beckenhauer, H. C. and Tuma, D. J. (1996) Betaine effects on hepatic methionine metabolism elicited by short-term ethanol feeding. Alcohol 13, 483-486.
-
(1996)
Alcohol
, vol.13
, pp. 483-486
-
-
Barak, A.J.1
Beckenhauer, H.C.2
Tuma, D.J.3
-
67
-
-
0027318064
-
Dietary betaine promotes generation of hepatic S-adenosylmethionine and protects the liver from ethanol-induced fatty infiltration
-
Barak, A. J., Beckenhauer, H. C., Junnila, M. and Tuma, D. J. (1993) Dietary betaine promotes generation of hepatic S-adenosylmethionine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin. Exp. Res. 17, 552-555.
-
(1993)
Alcohol Clin. Exp. Res.
, vol.17
, pp. 552-555
-
-
Barak, A.J.1
Beckenhauer, H.C.2
Junnila, M.3
Tuma, D.J.4
-
68
-
-
0037162531
-
Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig
-
Halsted, C. H., Villanueva, J. A., Devlin, A. M., Niemela, O., Parkkila, S., Garrow, T. A., Wallock, L. M., Shigenaga, M. K., Melnyk, S. And James, S. J. (2002) Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig. Proc. Natl. Acad. Sci. USA 99, 10072-10077.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10072-10077
-
-
Halsted, C.H.1
Villanueva, J.A.2
Devlin, A.M.3
Niemela, O.4
Parkkila, S.5
Garrow, T.A.6
Wallock, L.M.7
Shigenaga, M.K.8
Melnyk, S.9
James, S.J.10
-
69
-
-
0025890221
-
Hepatic transmethylation and blood alcohol levels
-
Barak, A. J., Beckenhauer, H. C. and Tuma, D. J. (1991) Hepatic transmethylation and blood alcohol levels. Alcohol Alcohol. 26, 125-128.
-
(1991)
Alcohol Alcohol.
, vol.26
, pp. 125-128
-
-
Barak, A.J.1
Beckenhauer, H.C.2
Tuma, D.J.3
-
70
-
-
0015116983
-
Methionine metabolism in mammals: Regulation of homocysteine methyltransferases in rat tissue
-
Finkelstein, J. D., Kyle, W. and Harris, B. J. (1971) Methionine metabolism in mammals: regulation of homocysteine methyltransferases in rat tissue. Arch. Biochem. Biophys. 146, 84-92.
-
(1971)
Arch. Biochem. Biophys.
, vol.146
, pp. 84-92
-
-
Finkelstein, J.D.1
Kyle, W.2
Harris, B.J.3
-
71
-
-
0016371704
-
Methionine metabolism in mammals: Regulatory effects of S-adenosylhomocysteine
-
Finkelstein, J. D., Kyle, W. E. and Harris, B. J. (1974) Methionine metabolism in mammals: regulatory effects of S-adenosylhomocysteine. Arch. Biochem. Biophys. 165, 774-779.
-
(1974)
Arch. Biochem. Biophys.
, vol.165
, pp. 774-779
-
-
Finkelstein, J.D.1
Kyle, W.E.2
Harris, B.J.3
-
72
-
-
0031737909
-
Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat
-
Jacobs, R. L., House, J. D., Brosnan, M. E. and Brosnan, J. T. (1998) Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat. Diabetes 47, 1967-1970.
-
(1998)
Diabetes
, vol.47
, pp. 1967-1970
-
-
Jacobs, R.L.1
House, J.D.2
Brosnan, M.E.3
Brosnan, J.T.4
-
73
-
-
8544257376
-
Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acid
-
Nieman, K. M., Rowling, M. J., Garrow, T. A. and Schalinske, K. L. (2004) Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acid. J. Biol. Chem. 279, 45708-45712.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 45708-45712
-
-
Nieman, K.M.1
Rowling, M.J.2
Garrow, T.A.3
Schalinske, K.L.4
-
74
-
-
33646431671
-
Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in rat liver
-
Ratnam, S., Wijekoon, E. P., Hall, B., Garrow, T. A., Brosnan, M. E. and Brosnan, J. T. (2006) Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in rat liver. Am. J. Physiol. Endocrinol. Metab. 290, E933-E939.
-
(2006)
Am. J. Physiol. Endocrinol. Metab.
, vol.290
-
-
Ratnam, S.1
Wijekoon, E.P.2
Hall, B.3
Garrow, T.A.4
Brosnan, M.E.5
Brosnan, J.T.6
-
75
-
-
21944433018
-
Plasma choline and betaine and their relation to plasma homocysteine in normal pregnancy
-
Velzing-Aarts, F. V., Holm, P. I., Fokkema, M. R., van der Dijs, F. P., Ueland, P. M. and Muskiet, F. A. (2005) Plasma choline and betaine and their relation to plasma homocysteine in normal pregnancy. Am. J. Clin. Nutr. 81, 1383-1389.
-
(2005)
Am. J. Clin. Nutr.
, vol.81
, pp. 1383-1389
-
-
Velzing-Aarts, F.V.1
Holm, P.I.2
Fokkema, M.R.3
Van Der Dijs, F.P.4
Ueland, P.M.5
Muskiet, F.A.6
-
76
-
-
33645864368
-
Methionine flux to transsulfuration is enhanced in the long living Ames dwarf mouse
-
Uthus, E. O. and Brown-Borg, H. M. (2006) Methionine flux to transsulfuration is enhanced in the long living Ames dwarf mouse. Mech. Ageing Dev. 127, 444-450.
-
(2006)
Mech. Ageing Dev.
, vol.127
, pp. 444-450
-
-
Uthus, E.O.1
Brown-Borg, H.M.2
-
77
-
-
7944232175
-
Triiodothyronine treatment attenuates the induction of hepatic glycine N-methyltransferase by retinoic acid and elevates plasma homocysteine concentrations in rats
-
Tanghe, K. A., Garrow, T. A. and Schalinske, K. L. (2004) Triiodothyronine treatment attenuates the induction of hepatic glycine N-methyltransferase by retinoic acid and elevates plasma homocysteine concentrations in rats. J. Nutr. 134, 2913-2918.
-
(2004)
J. Nutr.
, vol.134
, pp. 2913-2918
-
-
Tanghe, K.A.1
Garrow, T.A.2
Schalinske, K.L.3
-
78
-
-
0027454075
-
MTX does not affect enhanced biosynthesis and metabolism of S-adenosylmethionine in testosterone-induced hypertrophic mouse kidney
-
Chmurzynska, W., Manteuffel-Cymborowska, M., Szlazak, M. and Grzelakowska-Sztabert, B. (1993) MTX does not affect enhanced biosynthesis and metabolism of S-adenosylmethionine in testosterone-induced hypertrophic mouse kidney. Adv. Exp. Med. Biol. 338, 699-702.
-
(1993)
Adv. Exp. Med. Biol.
, vol.338
, pp. 699-702
-
-
Chmurzynska, W.1
Manteuffel-Cymborowska, M.2
Szlazak, M.3
Grzelakowska-Sztabert, B.4
-
79
-
-
0020600474
-
Effects of nitrous oxide-induced inactivation of cobalamin on methionine and S-adenosylmethionine metabolism in the rat
-
Lumb, M., Sharer, N., Deacon, R., Jennings, P., Purkiss, P., Perry, J. and Chanarin, I. (1983) Effects of nitrous oxide-induced inactivation of cobalamin on methionine and S-adenosylmethionine metabolism in the rat. Biochim. Biophys. Acta 756, 354-359.
-
(1983)
Biochim. Biophys. Acta
, vol.756
, pp. 354-359
-
-
Lumb, M.1
Sharer, N.2
Deacon, R.3
Jennings, P.4
Purkiss, P.5
Perry, J.6
Chanarin, I.7
-
80
-
-
0022560576
-
Perturbation of methionine metabolism in sheep with nitrous-oxide-induced inactivation of cobalamin
-
Xue, G. P., Snoswell, A. M. and Runciman, W. B. (1986) Perturbation of methionine metabolism in sheep with nitrous-oxide-induced inactivation of cobalamin. Biochem. Int. 12, 61-69.
-
(1986)
Biochem. Int.
, vol.12
, pp. 61-69
-
-
Xue, G.P.1
Snoswell, A.M.2
Runciman, W.B.3
-
81
-
-
11144344914
-
High sodium chloride intake decreases betaine-homocysteine S-methyltransferase expression in guinea pig liver and kidney
-
Delgado-Reyes, C. V. and Garrow, T. A. (2005) High sodium chloride intake decreases betaine-homocysteine S-methyltransferase expression in guinea pig liver and kidney. Am. J. Physiol. Regul. Integr. Comp. Physiol. 228, R182-R187.
-
(2005)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.228
-
-
Delgado-Reyes, C.V.1
Garrow, T.A.2
-
82
-
-
0036714669
-
Acute valproate administration impairs methionine metabolism in rats
-
Ubeda, N., Alonso-Aperte, E. and Varela-Moreiras, G. (2002) Acute valproate administration impairs methionine metabolism in rats. J. Nutr. 132, 2737-2742.
-
(2002)
J. Nutr.
, vol.132
, pp. 2737-2742
-
-
Ubeda, N.1
Alonso-Aperte, E.2
Varela-Moreiras, G.3
-
83
-
-
33744538358
-
Transplacental arsenic plus postnatal 12-O-teradecanoyl phorbol-13-acetate exposures associated with hepatocarcinogenesis induce similar aberrant gene expression patterns in male and female mouse liver
-
Liu, J., Xie, Y., Merrick, B. A., Shen, J., Ducharme, D. M., Collins, J., Diwan, B. A., Logsdon, D. and Waalkes, M. P. (2006) Transplacental arsenic plus postnatal 12-O-teradecanoyl phorbol-13-acetate exposures associated with hepatocarcinogenesis induce similar aberrant gene expression patterns in male and female mouse liver. Toxicol. Appl. Pharmacol. 213, 216-223.
-
(2006)
Toxicol. Appl. Pharmacol.
, vol.213
, pp. 216-223
-
-
Liu, J.1
Xie, Y.2
Merrick, B.A.3
Shen, J.4
Ducharme, D.M.5
Collins, J.6
Diwan, B.A.7
Logsdon, D.8
Waalkes, M.P.9
-
84
-
-
0037364454
-
Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency
-
Schwahn, B. C., Chen, Z., Laryea, M. D., Wendel, U., Lussier-Cacan, S., Genest, J. Jr, Mar, M. H., Zeisel, S. H., Castro, C., Garrow, T. and Rozen, R. (2003) Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency. FASEB J. 17, 512-514.
-
(2003)
FASEB J.
, vol.17
, pp. 512-514
-
-
Schwahn, B.C.1
Chen, Z.2
Laryea, M.D.3
Wendel, U.4
Lussier-Cacan, S.5
Genest Jr., J.6
Mar, M.H.7
Zeisel, S.H.8
Castro, C.9
Garrow, T.10
Rozen, R.11
-
85
-
-
23344449775
-
Physiological regulation of phospholipid methylation alters plasma homocysteine in mice
-
Jacobs, R. L., Stead, L. M., Devlin, C., Tabas, I., Brosnan, M. E., Brosnan, J. T. and Vance, D. E. (2005) Physiological regulation of phospholipid methylation alters plasma homocysteine in mice. J. Biol. Chem. 280, 28299-28305.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 28299-28305
-
-
Jacobs, R.L.1
Stead, L.M.2
Devlin, C.3
Tabas, I.4
Brosnan, M.E.5
Brosnan, J.T.6
Vance, D.E.7
-
86
-
-
2342501877
-
Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency
-
Schwahn, B. C., Wendel, U., Lussier-Cacan, S., Mar, M. H., Zeisel, S. H., Leclerc, D., Castro, C., Garrow, T. and Rozen, R. (2004) Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency. Metabolism 53, 594-599.
-
(2004)
Metabolism
, vol.53
, pp. 594-599
-
-
Schwahn, B.C.1
Wendel, U.2
Lussier-Cacan, S.3
Mar, M.H.4
Zeisel, S.H.5
Leclerc, D.6
Castro, C.7
Garrow, T.8
Rozen, R.9
-
87
-
-
4043064391
-
Role of TNF-alpha in ethanol-induced hyperhomocysteinemia and murine alcoholic liver injury
-
Ji, C., Deng, Q. and Kaplowitz, N. (2004) Role of TNF-alpha in ethanol-induced hyperhomocysteinemia and murine alcoholic liver injury. Hepatology 40, 442-451.
-
(2004)
Hepatology
, vol.40
, pp. 442-451
-
-
Ji, C.1
Deng, Q.2
Kaplowitz, N.3
-
88
-
-
0033838043
-
Association of betaine-homocysteine S-methyltransferase with microtubules
-
Sandu, C., Nick, P., Hess, D., Schiltz, E., Garrow, T. A. and Brandsch, R. (2000) Association of betaine-homocysteine S-methyltransferase with microtubules. Biol. Chem. 381, 619-622.
-
(2000)
Biol. Chem.
, vol.381
, pp. 619-622
-
-
Sandu, C.1
Nick, P.2
Hess, D.3
Schiltz, E.4
Garrow, T.A.5
Brandsch, R.6
-
89
-
-
22644439789
-
Screening of hepatocyte proteins binding to complete S protein of hepatitis B virus by yeast-two hybrid system
-
Bai, G. Q., Cheng, J., Zhang, S. L., Huang, Y. P., Wang, L., Liu, Y. and Lin, S. M. (2005) Screening of hepatocyte proteins binding to complete S protein of hepatitis B virus by yeast-two hybrid system. World, J. Gastroenterol. 11, 3899-3904.
-
(2005)
World, J. Gastroenterol.
, vol.11
, pp. 3899-3904
-
-
Bai, G.Q.1
Cheng, J.2
Zhang, S.L.3
Huang, Y.P.4
Wang, L.5
Liu, Y.6
Lin, S.M.7
-
90
-
-
2942587184
-
In vitro modification of betaine-homocysteine S-methyltransferase by tissue-type transglutaminase
-
Ichikawa, A., Ohashi, Y., Terada, S., Natsuka, S. and Ikura, K. (2004) In vitro modification of betaine-homocysteine S-methyltransferase by tissue-type transglutaminase. Int. J. Biochem. Cell. Biol. 36, 1981-1992.
-
(2004)
Int. J. Biochem. Cell. Biol.
, vol.36
, pp. 1981-1992
-
-
Ichikawa, A.1
Ohashi, Y.2
Terada, S.3
Natsuka, S.4
Ikura, K.5
-
91
-
-
0033591236
-
Autolyso-somal membrane-associated betaine homocysteine methyltransferase: Limited degradation fragment of a sequestered cytosolic enzyme monitoring autophagy
-
Ueno, T., Ishidoh, K., Mineki, R., Tanida, I., Murayama, K., Kadowaki, M. and Kominami, E. (1999) Autolyso-somal membrane-associated betaine homocysteine methyltransferase: limited degradation fragment of a sequestered cytosolic enzyme monitoring autophagy. J. Biol. Chem. 274, 15222-15229.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15222-15229
-
-
Ueno, T.1
Ishidoh, K.2
Mineki, R.3
Tanida, I.4
Murayama, K.5
Kadowaki, M.6
Kominami, E.7
-
92
-
-
0035117521
-
Leupeptin-induced appearance of partial fragment of betaine homocysteine methyltransferase during autophagic maturation in rat hepatocytes
-
Furuya, N., Kanazawa, T., Fujimura, S., Ueno, T., Kominami, E. and Kadowaki, M. (2001) Leupeptin-induced appearance of partial fragment of betaine homocysteine methyltransferase during autophagic maturation in rat hepatocytes. J. Biochem. 129, 313-320.
-
(2001)
J. Biochem.
, vol.129
, pp. 313-320
-
-
Furuya, N.1
Kanazawa, T.2
Fujimura, S.3
Ueno, T.4
Kominami, E.5
Kadowaki, M.6
-
93
-
-
0034647819
-
B48 preferentially translated over B100 in cells with increased endogenous apoB mRNA
-
Collins, H. L., Sparks, C. E. and Sparks, J. D. (2000) B48 preferentially translated over B100 in cells with increased endogenous apoB mRNA. Biochem. Biophys. Res. Commun. 273, 1156-1160.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.273
, pp. 1156-1160
-
-
Collins, H.L.1
Sparks, C.E.2
Sparks, J.D.3
-
94
-
-
33645755849
-
Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine-homocysteine S-methyltransferase
-
Sparks, J. D., Collins, H. L., Chirieac, D. V., Cianci, J., Jokinen, J., Sowden, M. P., Galloway, C. A. and Sparks, C. E. (2006) Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine-homocysteine S-methyltransferase. Biochem, J. 395, 363-371.
-
(2006)
Biochem, J.
, vol.395
, pp. 363-371
-
-
Sparks, J.D.1
Collins, H.L.2
Chirieac, D.V.3
Cianci, J.4
Jokinen, J.5
Sowden, M.P.6
Galloway, C.A.7
Sparks, C.E.8
-
95
-
-
20044363320
-
Proteome analysis of human hepatocellular carcinoma tissues by two-dimensional difference gel electrophoresis and mass spectrometry
-
Liang, C. R., Leow, C. K., Neo, J. C., Tan, G. S., Lo, S. L., Lim, J. W., Seow, T. K., Lai, P. B. and Cheng, M. C. (2005) Proteome analysis of human hepatocellular carcinoma tissues by two-dimensional difference gel electrophoresis and mass spectrometry. Proteomics 5, 2258-2271.
-
(2005)
Proteomics
, vol.5
, pp. 2258-2271
-
-
Liang, C.R.1
Leow, C.K.2
Neo, J.C.3
Tan, G.S.4
Lo, S.L.5
Lim, J.W.6
Seow, T.K.7
Lai, P.B.8
Cheng, M.C.9
-
96
-
-
0033821506
-
Is the increase in serum cystathionine levels in patients with liver cirrhosis a consequence of impaired homocysteine transsulfuration at the level of gamma-cystathionase?
-
Look, M. P., Riezler, R., Reichel, C., Brensing, K. A., Rockstroh, J. K., Stabler S.P, Spengler, U., Berthold, H. K. and Sauerbruch, T. (2000) Is the increase in serum cystathionine levels in patients with liver cirrhosis a consequence of impaired homocysteine transsulfuration at the level of gamma-cystathionase? Scand. J. Gastroenterol. 35, 866-872.
-
(2000)
Scand. J. Gastroenterol.
, vol.35
, pp. 866-872
-
-
Look, M.P.1
Riezler, R.2
Reichel, C.3
Brensing, K.A.4
Rockstroh, J.K.5
Stabler, S.P.6
Spengler, U.7
Berthold, H.K.8
Sauerbruch, T.9
-
97
-
-
0034999383
-
Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations
-
McGregor, D. O., Dellow, W. J., Lever, M., George, P. M., Robson, R. A. and Chambers, S. T. (2001) Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations. Kidney Int. 59, 2267-2272.
-
(2001)
Kidney Int.
, vol.59
, pp. 2267-2272
-
-
McGregor, D.O.1
Dellow, W.J.2
Lever, M.3
George, P.M.4
Robson, R.A.5
Chambers, S.T.6
-
98
-
-
0033658966
-
Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma
-
Avila, M. A., Berasain, C., Torres, L., Martin-Duce, A., Corrales, F. J., Yang, H., Prieto, J., Lu, S. C., Caballería, J., Rodes, J. and Mato, J. M. (2000) Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma. J. Hepatol. 33, 907-914.
-
(2000)
J. Hepatol.
, vol.33
, pp. 907-914
-
-
Avila, M.A.1
Berasain, C.2
Torres, L.3
Martin-Duce, A.4
Corrales, F.J.5
Yang, H.6
Prieto, J.7
Lu, S.C.8
Caballería, J.9
Rodes, J.10
Mato, J.M.11
-
99
-
-
0037987813
-
Betaine homocysteine methyltransferase: Gene cloning and expression analysis in rat liver cirrhosis
-
Forestier, M., Banninger, R., Reichen, J. and Solioz, M. (2003) Betaine homocysteine methyltransferase: gene cloning and expression analysis in rat liver cirrhosis. Biochim. Biophys. Acta 1638, 29-34.
-
(2003)
Biochim. Biophys. Acta
, vol.1638
, pp. 29-34
-
-
Forestier, M.1
Banninger, R.2
Reichen, J.3
Solioz, M.4
-
100
-
-
0021825085
-
Disturbance of methyl group metabolism in alloxan-diabetic sheep
-
Xue, G. P. and Snoswell, A. M. (1985) Disturbance of methyl group metabolism in alloxan-diabetic sheep. Biochem. Int. 10, 897-905.
-
(1985)
Biochem. Int.
, vol.10
, pp. 897-905
-
-
Xue, G.P.1
Snoswell, A.M.2
-
101
-
-
30744462183
-
Homocysteine metabolism in ZDF (type 2) diabetic rats
-
Wijekoon, E. P., Hall, B., Ratnam, S., Brosnan, M. E., Zeisel, S. H. and Brosnan, J. T. (2005) Homocysteine metabolism in ZDF (type 2) diabetic rats. Diabetes 54, 3245-3251.
-
(2005)
Diabetes
, vol.54
, pp. 3245-3251
-
-
Wijekoon, E.P.1
Hall, B.2
Ratnam, S.3
Brosnan, M.E.4
Zeisel, S.H.5
Brosnan, J.T.6
-
102
-
-
33745511245
-
The use of betaine in the treatment of elevated homocysteine
-
Lawson-Yuen, A. and Levy, H. L. (2006) The use of betaine in the treatment of elevated homocysteine. Mol. Genet. Metab. 88, 201-207.
-
(2006)
Mol. Genet. Metab.
, vol.88
, pp. 201-207
-
-
Lawson-Yuen, A.1
Levy, H.L.2
-
103
-
-
33645743547
-
Improvement in stroke mortality in Canada and the United States, 1990 to 2002
-
Yang, Q., Botto, L. D., Ericsson, J. D., Berry, R. J., Sambell, C., Johansen, H. and Friedman, J. M. (2006) Improvement in stroke mortality in Canada and the United States, 1990 to 2002. Circulation 113, 1335-1343.
-
(2006)
Circulation
, vol.113
, pp. 1335-1343
-
-
Yang, Q.1
Botto, L.D.2
Ericsson, J.D.3
Berry, R.J.4
Sambell, C.5
Johansen, H.6
Friedman, J.M.7
-
104
-
-
27644521579
-
Vitamin intervention for stroke prevention trial
-
Spence, J. D., Bang, H., Chambless, L. E. and Stampfer, M. J. (2005) Vitamin intervention for stroke prevention trial. Stroke 36, 2404-2409.
-
(2005)
Stroke
, vol.36
, pp. 2404-2409
-
-
Spence, J.D.1
Bang, H.2
Chambless, L.E.3
Stampfer, M.J.4
-
105
-
-
1942476900
-
Cystathionine beta-synthase deficiency: Effects of betaine supplementation after methionine restriction in B6-nonresponsive homocystinuria
-
nd (2004) Cystathionine beta-synthase deficiency: effects of betaine supplementation after methionine restriction in B6-nonresponsive homocystinuria. Genet. Med. 6, 90-95.
-
(2004)
Genet. Med.
, vol.6
, pp. 90-95
-
-
Singh, R.H.1
Kruger, W.D.2
Wang, L.3
Pasquali, M.4
Elsas II, E.J.5
-
106
-
-
0038497517
-
Classical homocystinuria: Vascular risk and its prevention
-
Yap, S. (2003) Classical homocystinuria: vascular risk and its prevention. J. Inherit. Metab. Dis. 26, 259-265.
-
(2003)
J. Inherit. Metab. Dis.
, vol.26
, pp. 259-265
-
-
Yap, S.1
-
107
-
-
0033730997
-
Betaine-homocysteine methyltransferase (BHMT): Genomic sequencing and relevance to hyperhomocysteinemia and vascular disease in humans
-
Heil, S. G., Lievers, K. J., Boers, G. H., Verhoef, P., den Heijer, M., Trijbels, F. J. and Blom, H. J. (2000) Betaine-homocysteine methyltransferase (BHMT): genomic sequencing and relevance to hyperhomocysteinemia and vascular disease in humans. Mol. Genet. Metab. 71, 511-519.
-
(2000)
Mol. Genet. Metab.
, vol.71
, pp. 511-519
-
-
Heil, S.G.1
Lievers, K.J.2
Boers, G.H.3
Verhoef, P.4
Den Heijer, M.5
Trijbels, F.J.6
Blom, H.J.7
-
108
-
-
0038124366
-
Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease
-
Weisberg, I. S., Park, E., Ballman, K. V., Berger, P., Nunn, M., Suh, D. S., Breaksa, A. P. 3rd, Garrow, T. A. and Rozen, R. (2003) Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease. Atherosclerosis 167, 205-214.
-
(2003)
Atherosclerosis
, vol.167
, pp. 205-214
-
-
Weisberg, I.S.1
Park, E.2
Ballman, K.V.3
Berger, P.4
Nunn, M.5
Suh, D.S.6
Breaksa III, A.P.7
Garrow, T.A.8
Rozen, R.9
-
109
-
-
0042322356
-
Common variant in betaine-homocysteine methyltransferase (BHMT) and risk for spina bifida
-
Morin, I., Platt, R., Weisberg, I., Sabbaghian, N., Wu, Q., Garrow, T. A., Rozen, R. (2003) Common variant in betaine-homocysteine methyltransferase (BHMT) and risk for spina bifida. Am. J. Med. Genet 119A, 172-176.
-
(2003)
Am. J. Med. Genet
, vol.119 A
, pp. 172-176
-
-
Morin, I.1
Platt, R.2
Weisberg, I.3
Sabbaghian, N.4
Wu, Q.5
Garrow, T.A.6
Rozen, R.7
-
110
-
-
0042668586
-
Genetic linkage of candidate genes in families with abdominal aortic aneurysms?
-
van Vlijmen-van Keulen, C. J., Vahl, A. C., Hennekam, R. C., Rauwerda, J. A. and Pals, G. (2003) Genetic linkage of candidate genes in families with abdominal aortic aneurysms? Eur. J. Vasc. Endovasc. Surg. 26, 205-210.
-
(2003)
Eur. J. Vasc. Endovasc. Surg.
, vol.26
, pp. 205-210
-
-
Van Vlijmen-van Keulen, C.J.1
Vahl, A.C.2
Hennekam, R.C.3
Rauwerda, J.A.4
Pals, G.5
-
111
-
-
0016243140
-
Mechanisms initiating cataract formation
-
Kinoshita, J. H. (1974) Mechanisms initiating cataract formation. Invest. Ophthalmol. 13, 713-724.
-
(1974)
Invest. Ophthalmol.
, vol.13
, pp. 713-724
-
-
Kinoshita, J.H.1
-
112
-
-
26244454970
-
Gene expression in rats with Barrett's esophagus and esophageal adenocarcinoma induced by gastroduodenoesophageal reflux
-
Cheng, P., Gong, J., Wang, T., Chen, J., Liu, G. S. and Zhang, R. (2005) Gene expression in rats with Barrett's esophagus and esophageal adenocarcinoma induced by gastroduodenoesophageal reflux. World, J. Gastroenterol. 11, 5117-5122.
-
(2005)
World, J. Gastroenterol.
, vol.11
, pp. 5117-5122
-
-
Cheng, P.1
Gong, J.2
Wang, T.3
Chen, J.4
Liu, G.S.5
Zhang, R.6
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