α1D-adrenoceptor-induced relaxation on rat carotid artery is impaired during the endothelial dysfunction evoked in the early stages of hyperhomocysteinemia

European Journal of Pharmacology

Volumn 543, Issue 1-3, 2006, Pages 83-91

  de Andrade, Claudia Roberta ^a   Fukada, Sandra Yasuyo ^a   Olivon, Vania Claudia ^a   de Godoy, Marcio A F ^a   Haddad, Renato ^b   Eberlin, Marcos Nogueira ^b   Cunha, Fernando Queiroz ^a   de Souza, Heraldo Possolo ^a   Laurindo, Francisco R M ^a   de Oliveira, Ana Maria ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

1D adrenoceptor; Carotid artery; Hyperhomocysteinemia; Modulation; Nitric oxide; Oxidative stress; Phenylephrine; Relaxation

Indexed keywords

5 METHYLURAPIDIL; 8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; PRAZOSIN; SUPEROXIDE; SUPEROXIDE DISMUTASE; 5-METHYLURAPIDIL; ADRENERGIC RECEPTOR ALPHA(1D); ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ENZYME INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PIPERAZINE DERIVATIVE;

ANIMAL TISSUE; ARTERY DILATATION; ARTICLE; BLOOD VESSEL REACTIVITY; CAROTID ARTERY; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVITY; HYPERHOMOCYSTEINEMIA; HYPOTHESIS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR ENDOTHELIUM; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PATHOPHYSIOLOGY; VASOCONSTRICTION; VASODILATATION; WISTAR RAT;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; CAROTID ARTERIES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HYPERHOMOCYSTEINEMIA; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; PIPERAZINES; PRAZOSIN; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; SUPEROXIDE DISMUTASE; SUPEROXIDES; VASOCONSTRICTION; VASODILATION;

EID: 33746190611     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.06.003     Document Type: Article

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