Polar aprotic modifiers for chromatographic separation and back-exchange reduction for protein hydrogen/deuterium exchange monitored by fourier transform ion cyclotron resonance mass spectrometry

Journal of the American Society for Mass Spectrometry

Volumn 23, Issue 4, 2012, Pages 699-707

  Valeja, Santosh G ^a   Emmett, Mark R ^a,b   Marshall, Alan G ^a,b  

^a FLORIDA STATE UNIVERSITY   (United States)

^b FLORIDA STATE UNIVERSITY   (United States)

Author keywords

FT ICR; FTMS; Luteinizing hormone releasing hormone (LHRH); Myoglobin

Indexed keywords

APROTIC; CHROMATOGRAPHIC SEPARATIONS; FOURIER TRANSFORM ION CYCLOTRON RESONANCE MASS SPECTROMETRY; FT-ICR; FT-ICR MS; FTMS; H/D EXCHANGE; HYDROGEN/DEUTERIUM EXCHANGE; ISOTOPIC DISTRIBUTIONS; LUTEINIZING HORMONE RELEASING HORMONES; MOBILE PHASE; MYOGLOBIN; N-METHYLPYRROLIDONE; ORGANIC MODIFIER; PROTEIN STRUCTURES; PROTEIN-PROTEIN INTERACTIONS; PROTEOLYTIC PEPTIDES; QUANTITATIVE DETERMINATIONS; REVERSED-PHASE LIQUID CHROMATOGRAPHY; SOLVENT COMPOSITION; SUPER CRITICAL FLUID CHROMATOGRAPHY;

DIMETHYLFORMAMIDE; GAS CHROMATOGRAPHY; HYDROGEN; MASS SPECTROMETRY; ORGANIC SOLVENTS; PEPTIDES;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

1 METHYL 2 PYRROLIDINONE; DEUTERIUM; HYDROGEN; N,N DIMETHYLFORMAMIDE; PEPTIDE; PROTEIN; SOLVENT; WATER;

ARTICLE; BACK EXCHANGE; CHEMICAL COMPOSITION; CHEMICAL MODIFICATION; CHEMICAL PHENOMENA; DEUTERIUM HYDROGEN EXCHANGE; ELECTROSPRAY MASS SPECTROMETRY; ION CYCLOTRON RESONANCE MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; ONLINE ANALYSIS; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; DEUTERIUM EXCHANGE MEASUREMENT; DIMETHYLFORMAMIDE; FOURIER ANALYSIS; HORSES; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MASS SPECTROMETRY; PEPTIDE FRAGMENTS; PROTEINS; PYRROLIDINONES;

EID: 84862517885     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-011-0329-z     Document Type: Article

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