Investigation of amide hydrogen back-exchange in Asp and His repeats measured by hydrogen (1H/2H) exchange mass spectrometry

International Journal of Mass Spectrometry

Volumn 302, Issue 1-3, 2011, Pages 110-115

  Rand, Kasper D ^a   Lund, Frederik W ^a   Amon, Sabine ^a   Jørgensen, Thomas J D ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Back exchange; Electron transfer dissociation; Hydrogen deuterium exchange

Indexed keywords

EID: 79954634131     PISSN: 13873806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijms.2010.08.027     Document Type: Article

References (27)

1. T.E. Wales, and J.R. Engen Hydrogen exchange mass spectrometry for the analysis of protein dynamics Mass Spectrom. Rev. 25 2006 158 170
2. Z. Zhang, and D.L. Smith Determination of amide hydrogen exchange by mass spectrometry: a new tool for protein structure elucidation Protein Sci. 2 1993 522 531 (Pubitemid 23119303)
3. V. Hindie, A. Stroba, H. Zhang, L.A. Lopez-Garcia, L. Idrissova, S. Zeuzem, D. Hirschberg, F. Schaeffer, T.J.D. Jorgensen, M. Engel, P.M. Alzari, and R.M. Biondi Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1 Nat. Chem. Biol. 5 2009 758 764
4. K.D. Rand, M.D. Andersen, O.H. Olsen, T.J.D. Jorgensen, H. Ostergaard, O.N. Jensen, H.R. Stennicke, and E. Persson The origins of enhanced activity in factor VIIa analogs and the interplay between key allosteric sites revealed by hydrogen exchange mass spectrometry J. Biol. Chem. 283 2008 13378 13387
5. M. Kjaergaard, H. Gardsvoll, D. Hirschberg, S. Nielbo, A. Mayasundari, C.B. Peterson, A. Jansson, T.J.D. Jorgensen, F.M. Poulsen, and M. Ploug Solution structure of recombinant somatomedin B domain from vitronectin produced in Pichia pastoris Protein Sci. 16 2007 1934 1945 (Pubitemid 47367116)
6. K.D. Rand, T.J.D. Jorgensen, O.H. Olsen, E. Persson, O.N. Jensen, H.R. Stennicke, and M.D. Andersen Allosteric activation of coagulation factor VIIa visualized by hydrogen exchange J. Biol. Chem. 281 2006 23018 23024
7. M.R. Emmett, S. Kazazic, A.G. Marshall, W. Chen, S.D.H. Shi, B. Bolanos, and M.J. Greig Supercritical fluid chromatography reduction of hydrogen/deuterium back exchange in solution-phase hydrogen/deuterium exchange with mass spectrometric analysis Anal. Chem. 78 2006 7058 7060 (Pubitemid 44522564)
8. Y. Bai, J.S. Milne, L. Mayne, and S.W. Englander Primary structure effects on peptide group hydrogen exchange Proteins 17 1993 75 86 (Pubitemid 23261059)
9. 2H) scrambling upon gas phase fragmentation Anal. Chem. 79 2007 8686 8693 (Pubitemid 350171380)
10. M. Zehl, K.D. Rand, O.N. Jensen, and T.J.D. Jorgensen Electron transfer dissociation facilitates the measurement of deuterium incorporation into selectively labeled peptides with single residue resolution J. Am. Chem. Soc. 130 2008 17453 17459
11. K.D. Rand, C.M. Adams, R.A. Zubarev, and T.J.D. Jorgensen Electron capture proceeds with a low degree of intramolecular migration of peptide amide hydrogens J. Am. Chem. Soc. 130 2008 1341 1349 (Pubitemid 351171014)
12. S. Karlin, L. Brocchieri, A. Bergman, J. Mrazek, and A.J. Gentles Amino acid runs in eukaryotic proteomes and disease associations Proc. Natl. Acad. Sci. U.S.A. 99 2002 333 338 (Pubitemid 34060363)
13. D.D. Weis, J.R. Engen, and I.J. Kass Semi-automated data processing of hydrogen exchange mass spectra using HX-Express J. Am. Soc. Mass Spectrom. 17 2006 1700 1703 (Pubitemid 44809951)
14. C.E. Dempsey Hydrogen-bond stabilities in the isolated alamethicin helix - ph-dependent amide exchange measurements in methanol J. Am. Chem. Soc. 117 1995 7526 7534
15. E. Salichs, A. Ledda, L. Mularoni, M.M. Alba, and S. de la Luna Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment PLoS Genet. 5 2009
16. W. Burkitt, and G. O'Connor Assessment of the repeatability and reproducibility of hydrogen/deuterium exchange mass spectrometry measurements Rapid Commun. Mass Spectrom. 22 2008 3893 3901
17. L.M. Feng, R. Orlando, and J.H. Prestegard Amide proton back-exchange in deuterated peptides: applications to MS and NMR analyses Anal. Chem. 78 2006 6885 6892 (Pubitemid 44522540)
18. N. Bache, K.D. Rand, P. Roepstorff, M. Ploug, and T.J.D. Jorgensen Hydrogen atom scrambling in selectively labeled anionic peptides upon collisional activation by MALDI tandem time-of-flight mass spectrometry J. Am. Soc. Mass Spectrom. 19 2008 1719 1725
19. T.J.D. Jorgensen, H. Gardsvoll, M. Ploug, and P. Roepstorff Intramolecular migration of amide hydrogens in protonated peptides upon collisional activation J. Am. Chem. Soc. 127 2005 2785 2793 (Pubitemid 40327841)
20. T.J.D. Jorgensen, N. Bache, P. Roepstorff, H. Gardsvoll, and M. Ploug Collisional activation by MALDI tandem time-of-flight mass spectrometry induces intramolecular migration of amide hydrogens in protonated peptides Mol. Cell. Proteomics 4 2005 1910 1919 (Pubitemid 41830185)
21. N. Bache, K.D. Rand, P. Roepstorff, and T.J.D. Jorgensen Gas-phase fragmentation of peptides by MALDI in-source decay with limited amide hydrogen (H-1/H-2) scrambling Anal. Chem. 80 2008 6431 6435
22. K.D. Rand, M. Zehl, O.N. Jensen, and T.J.D. Jorgensen Protein hydrogen exchange measured at single-residue resolution by electron transfer dissociation mass spectrometry Anal. Chem. 81 2009 5577 5584
23. J.X. Pan, J. Han, C.H. Borchers, and L. Konermann Hydrogen/deuterium exchange mass spectrometry with top-down electron capture dissociation for characterizing structural transitions of a 17 kDa protein J. Am. Chem. Soc. 131 2009 12801 12808
24. R.R. Abzalimov, D.A. Kaplan, M.L. Easterling, and I.A. Kaltashov Protein conformations can be probed in top-down HDX MS experiments utilizing electron transfer dissociation of protein ions without hydrogen scrambling J. Am. Soc. Mass Spectrom. 20 2009 1514 1517
25. J. Pan, J. Han, C.H. Borchers, and L. Konermann Electron capture dissociation of electrosprayed protein ions for spatially resolved hydrogen exchange measurements J. Am. Chem. Soc. 130 2008 11574 11575
26. C.N. Pace, and J.M. Scholtz A helix propensity scale based on experimental studies of peptides and proteins Biophys. J. 75 1998 422 427 (Pubitemid 28311831)
27. P.S. Kim, and R.L. Baldwin Influence of charge on the rate of amide proton-exchange Biochemistry 21 1982 1 5