-
1
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
B.D. Manning, and L.C. Cantley AKT/PKB signaling: navigating downstream Cell 129 2007 1261 1274
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
2
-
-
33847314539
-
The phosphatidyl inositol 3-kinase signaling network: Implications for human breast cancer
-
R.L. Dillon, D.E. White, and W.J. Muller The phosphatidyl inositol 3-kinase signaling network: implications for human breast cancer Oncogene 26 2007 1338 1345
-
(2007)
Oncogene
, vol.26
, pp. 1338-1345
-
-
Dillon, R.L.1
White, D.E.2
Muller, W.J.3
-
3
-
-
78650510609
-
MTOR: From growth signal integration to cancer, diabetes and ageing
-
R. Zoncu, A. Efeyan, and D.M. Sabatini mTOR: from growth signal integration to cancer, diabetes and ageing Nat. Rev. Mol. Cell Biol. 12 2011 21 35
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 21-35
-
-
Zoncu, R.1
Efeyan, A.2
Sabatini, D.M.3
-
4
-
-
67749122122
-
Targeting PI3K signaling in cancer: Opportunities, challenges and limitations
-
J.A. Engelman Targeting PI3K signaling in cancer: opportunities, challenges and limitations Nat. Rev. Cancer 9 2009 550 562
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 550-562
-
-
Engelman, J.A.1
-
5
-
-
77952007543
-
Mammalian target of rapamycin (mTOR): Conducting the cellular signaling symphony
-
K.G. Foster, and D.C. Fingar Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony J. Biol. Chem. 285 2010 14071 14077
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 14071-14077
-
-
Foster, K.G.1
Fingar, D.C.2
-
7
-
-
63749086305
-
ErbB receptors and signaling pathways in cancer
-
N.E. Hynes, and G. MacDonald ErbB receptors and signaling pathways in cancer Curr. Opin. Cell Biol. 21 2009 177 184
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 177-184
-
-
Hynes, N.E.1
MacDonald, G.2
-
9
-
-
0038398622
-
The insulin-like growth factor system and cancer
-
D. LeRoith, and C.T. Roberts Jr. The insulin-like growth factor system and cancer Cancer Lett. 195 2003 127 137
-
(2003)
Cancer Lett.
, vol.195
, pp. 127-137
-
-
Leroith, D.1
Roberts Jr., C.T.2
-
10
-
-
63749118028
-
DNA-dependent protein kinase-mediated phosphorylation of protein kinase B requires a specific recognition sequence in the C-terminal hydrophobic motif
-
J. Park, J. Feng, Y. Li, O. Hammarsten, D.P. Brazil, and B.A. Hemmings DNA-dependent protein kinase-mediated phosphorylation of protein kinase B requires a specific recognition sequence in the C-terminal hydrophobic motif J. Biol. Chem. 284 2009 6169 6174
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 6169-6174
-
-
Park, J.1
Feng, J.2
Li, Y.3
Hammarsten, O.4
Brazil, D.P.5
Hemmings, B.A.6
-
11
-
-
54049143645
-
Contributions of integrin-linked kinase to breast cancer metastasis and tumourigenesis
-
C.V. Hinton, S. Avraham, and H.K. Avraham Contributions of integrin-linked kinase to breast cancer metastasis and tumourigenesis J. Cell. Mol. Med. 12 2008 1517 1526
-
(2008)
J. Cell. Mol. Med.
, vol.12
, pp. 1517-1526
-
-
Hinton, C.V.1
Avraham, S.2
Avraham, H.K.3
-
12
-
-
79958696694
-
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling
-
P.P. Hsu, S.A. Kang, J. Rameseder, Y. Zhang, K.A. Ottina, D. Lim, T.R. Peterson, Y. Choi, N.S. Gray, M.B. Yaffe, J.A. Marto, and D.M. Sabatini The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling Science 332 2011 1317 1322
-
(2011)
Science
, vol.332
, pp. 1317-1322
-
-
Hsu, P.P.1
Kang, S.A.2
Rameseder, J.3
Zhang, Y.4
Ottina, K.A.5
Lim, D.6
Peterson, T.R.7
Choi, Y.8
Gray, N.S.9
Yaffe, M.B.10
Marto, J.A.11
Sabatini, D.M.12
-
13
-
-
79958696336
-
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling
-
Y. Yu, S.O. Yoon, G. Poulogiannis, Q. Yang, X.M. Ma, J. Villén, N. Kubica, G.R. Hoffman, L.C. Cantley, S.P. Gygi, and J. Blenis Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling Science 332 2011 1322 1326
-
(2011)
Science
, vol.332
, pp. 1322-1326
-
-
Yu, Y.1
Yoon, S.O.2
Poulogiannis, G.3
Yang, Q.4
Ma, X.M.5
Villén, J.6
Kubica, N.7
Hoffman, G.R.8
Cantley, L.C.9
Gygi, S.P.10
Blenis, J.11
-
14
-
-
51349164790
-
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
-
A. Carracedo, L. Ma, J. Teruya-Feldstein, F. Rojo, L. Salmena, A. Alimonti, A. Egia, A.T. Sasaki, G. Thomas, S.C. Kozma, A. Papa, C. Nardella, L.C. Cantley, J. Baselga, and P.P. Pandolfi Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer J. Clin. Invest. 118 2008 3065 3074
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3065-3074
-
-
Carracedo, A.1
Ma, L.2
Teruya-Feldstein, J.3
Rojo, F.4
Salmena, L.5
Alimonti, A.6
Egia, A.7
Sasaki, A.T.8
Thomas, G.9
Kozma, S.C.10
Papa, A.11
Nardella, C.12
Cantley, L.C.13
Baselga, J.14
Pandolfi, P.P.15
-
15
-
-
77954235821
-
Targeting mTOR: Prospects for mTOR complex 2 inhibitors in cancer therapy
-
C.A. Sparks, and D.A. Guertin Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy Oncogene 29 2010 3733 3744
-
(2010)
Oncogene
, vol.29
, pp. 3733-3744
-
-
Sparks, C.A.1
Guertin, D.A.2
-
16
-
-
71749106273
-
Fatty acids and breast cancer: Sensitization to treatments and prevention of metastatic re-growth
-
P. Bougnoux, N. Hajjaji, K. Maheo, C. Couet, and S. Chevalier Fatty acids and breast cancer: sensitization to treatments and prevention of metastatic re-growth Prog. Lipid Res. 49 2010 76 86
-
(2010)
Prog. Lipid Res.
, vol.49
, pp. 76-86
-
-
Bougnoux, P.1
Hajjaji, N.2
Maheo, K.3
Couet, C.4
Chevalier, S.5
-
17
-
-
3042767902
-
Dietary long-chain n-3 fatty acids for the prevention of cancer: A review of potential mechanisms
-
S.C. Larsson, M. Kumlin, M. Ingelman-Sundberg, and A. Wolk Dietary long-chain n-3 fatty acids for the prevention of cancer: a review of potential mechanisms Am. J. Clin. Nutr. 79 2004 935 945
-
(2004)
Am. J. Clin. Nutr.
, vol.79
, pp. 935-945
-
-
Larsson, S.C.1
Kumlin, M.2
Ingelman-Sundberg, M.3
Wolk, A.4
-
18
-
-
51349137876
-
Multi-targeted therapy of cancer by omega-3 fatty acids
-
I.M. Berquin, I.J. Edwards, and Y.Q. Chen Multi-targeted therapy of cancer by omega-3 fatty acids Cancer Lett. 269 2008 363 377
-
(2008)
Cancer Lett.
, vol.269
, pp. 363-377
-
-
Berquin, I.M.1
Edwards, I.J.2
Chen, Y.Q.3
-
19
-
-
58849102749
-
DHA induces ER stress and growth arrest in human colon cancer cells: Associations with cholesterol and calcium homeostasis
-
C.H. Jakobsen, G.L. Størvold, H. Bremseth, T. Follestad, K. Sand, M. Mack, K.S. Olsen, A.G. Lundemo, J.G. Iversen, H.E. Krokan, and S.A. Schønberg DHA induces ER stress and growth arrest in human colon cancer cells: associations with cholesterol and calcium homeostasis J. Lipid Res. 49 2008 2089 2100
-
(2008)
J. Lipid Res.
, vol.49
, pp. 2089-2100
-
-
Jakobsen, C.H.1
Størvold, G.L.2
Bremseth, H.3
Follestad, T.4
Sand, K.5
MacK, M.6
Olsen, K.S.7
Lundemo, A.G.8
Iversen, J.G.9
Krokan, H.E.10
Schønberg, S.A.11
-
20
-
-
21644462730
-
Mechanisms of omega-3 fatty acid-induced growth inhibition in MDA-MB-231 human breast cancer cells
-
P.D. Schley, H.B. Jijon, L.E. Robinson, and C.J. Field Mechanisms of omega-3 fatty acid-induced growth inhibition in MDA-MB-231 human breast cancer cells Breast Cancer Res. Treat. 92 2005 187 195
-
(2005)
Breast Cancer Res. Treat.
, vol.92
, pp. 187-195
-
-
Schley, P.D.1
Jijon, H.B.2
Robinson, L.E.3
Field, C.J.4
-
21
-
-
77956295532
-
Docosahexaenoic acid alters epidermal growth factor receptor-related signaling by disrupting its lipid raft association
-
K.R. Rogers, K.D. Kikawa, M. Mouradian, K. Hernandez, K.M. McKinnon, S.M. Ahwah, and R.S. Pardini Docosahexaenoic acid alters epidermal growth factor receptor-related signaling by disrupting its lipid raft association Carcinogenesis 31 2010 1523 1530
-
(2010)
Carcinogenesis
, vol.31
, pp. 1523-1530
-
-
Rogers, K.R.1
Kikawa, K.D.2
Mouradian, M.3
Hernandez, K.4
McKinnon, K.M.5
Ahwah, S.M.6
Pardini, R.S.7
-
22
-
-
0035036533
-
N-6 and n-3 polyunsaturated fatty acids differentially modulate oncogenic Ras activation in colonocytes
-
E.D. Collett, L.A. Davidson, Y.Y. Fan, J.R. Lupton, and R.S. Chapkin n-6 and n-3 polyunsaturated fatty acids differentially modulate oncogenic Ras activation in colonocytes Am. J. Physiol. Cell Physiol. 280 2001 C1066 C1075
-
(2001)
Am. J. Physiol. Cell Physiol.
, vol.280
-
-
Collett, E.D.1
Davidson, L.A.2
Fan, Y.Y.3
Lupton, J.R.4
Chapkin, R.S.5
-
23
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
M.G. Vander Heiden, L.C. Cantley, and C.B. Thompson Understanding the Warburg effect: the metabolic requirements of cell proliferation Science 324 2009 1029 1033
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
24
-
-
0029763569
-
Identification of a specific DNA region required for enhanced transcription of HER2/neu in the MDA-MB-453 breast cancer cell line
-
S.J. Miller, X. Xing, L. Xi, and M.C. Hung Identification of a specific DNA region required for enhanced transcription of HER2/neu in the MDA-MB-453 breast cancer cell line DNA Cell Biol. 15 1996 749 757
-
(1996)
DNA Cell Biol.
, vol.15
, pp. 749-757
-
-
Miller, S.J.1
Xing, X.2
Xi, L.3
Hung, M.C.4
-
25
-
-
0036834994
-
Aberrant expression of integrin and erbB subunits in breast cancer cell lines
-
H. Shimizu, N. Koyama, M. Asada, and K. Yoshimatsu Aberrant expression of integrin and erbB subunits in breast cancer cell lines Int. J. Oncol. 21 2002 1073 1079
-
(2002)
Int. J. Oncol.
, vol.21
, pp. 1073-1079
-
-
Shimizu, H.1
Koyama, N.2
Asada, M.3
Yoshimatsu, K.4
-
26
-
-
77949423592
-
The FGFR4 Y367C mutant is a dominant oncogene in MDA-MB-453 breast cancer cells
-
A. Roidl, P. Foo, W. Wong, C. Mann, S. Bechtold, H.J. Berger, S. Streit, J.E. Ruhe, S. Hart, A. Ullrich, and H.K. Ho The FGFR4 Y367C mutant is a dominant oncogene in MDA-MB-453 breast cancer cells Oncogene 29 2010 1543 1552
-
(2010)
Oncogene
, vol.29
, pp. 1543-1552
-
-
Roidl, A.1
Foo, P.2
Wong, W.3
Mann, C.4
Bechtold, S.5
Berger, H.J.6
Streit, S.7
Ruhe, J.E.8
Hart, S.9
Ullrich, A.10
Ho, H.K.11
-
27
-
-
0033629139
-
Comparison of action of paclitaxel and poly(L-glutamic acid)-paclitaxel conjugate in human breast cancer cells
-
E.A. Oldham, C. Li, S. Ke, S. Wallace, and P. Huang Comparison of action of paclitaxel and poly(L-glutamic acid)-paclitaxel conjugate in human breast cancer cells Int. J. Oncol. 16 2000 125 132
-
(2000)
Int. J. Oncol.
, vol.16
, pp. 125-132
-
-
Oldham, E.A.1
Li, C.2
Ke, S.3
Wallace, S.4
Huang, P.5
-
28
-
-
21344444336
-
Complex CGH alterations on chromosome arm 8p at candidate tumor suppressor gene loci in breast cancer cell lines
-
D.J. Venter, S.J. Ramus, F.M. Hammet, M. de Silva, A.M. Hutchins, V. Petrovic, G. Price, and J.E. Armes Complex CGH alterations on chromosome arm 8p at candidate tumor suppressor gene loci in breast cancer cell lines Cancer Genet. Cytogenet. 160 2005 134 140
-
(2005)
Cancer Genet. Cytogenet.
, vol.160
, pp. 134-140
-
-
Venter, D.J.1
Ramus, S.J.2
Hammet, F.M.3
De Silva, M.4
Hutchins, A.M.5
Petrovic, V.6
Price, G.7
Armes, J.E.8
-
29
-
-
1942542103
-
Extracting long-chain fatty acids from a fermentation medium
-
J.A. Lalman, and D.M. Bagley Extracting long-chain fatty acids from a fermentation medium J. Am. Oil Chem. Soc. 81 2004 105 110
-
(2004)
J. Am. Oil Chem. Soc.
, vol.81
, pp. 105-110
-
-
Lalman, J.A.1
Bagley, D.M.2
-
30
-
-
4644302460
-
An improved method for tissue long-chain acyl-CoA extraction and analysis
-
M.Y. Golovko, and E.J. Murphy An improved method for tissue long-chain acyl-CoA extraction and analysis J. Lipid Res. 45 2004 1777 1782
-
(2004)
J. Lipid Res.
, vol.45
, pp. 1777-1782
-
-
Golovko, M.Y.1
Murphy, E.J.2
-
31
-
-
4243190715
-
Preparation of fatty acid methyl esters and dimethyacetals from lipids with boron fluoride-methanol
-
W.R. Morrison, and L.M. Smith Preparation of fatty acid methyl esters and dimethyacetals from lipids with boron fluoride-methanol J. Lipid Res. 5 1964 600 608
-
(1964)
J. Lipid Res.
, vol.5
, pp. 600-608
-
-
Morrison, W.R.1
Smith, L.M.2
-
32
-
-
20044370874
-
Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members
-
D. DeFeo-Jones, S.F. Barnett, S. Fu, P.J. Hancock, K.M. Haskell, K.R. Leander, E. McAvoy, R.G. Robinson, M.E. Duggan, C.W. Lindsley, Z. Zhao, H.E. Huber, and R.E. Jones Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members Mol. Cancer Ther. 4 2005 271 279
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 271-279
-
-
Defeo-Jones, D.1
Barnett, S.F.2
Fu, S.3
Hancock, P.J.4
Haskell, K.M.5
Leander, K.R.6
McAvoy, E.7
Robinson, R.G.8
Duggan, M.E.9
Lindsley, C.W.10
Zhao, Z.11
Huber, H.E.12
Jones, R.E.13
-
33
-
-
58849120491
-
Role of a novel PH-kinase domain interface in PKB/Akt regulation: Structural mechanism for allosteric inhibition
-
V. Calleja, M. Laguerre, P.J. Parker, and B. Larijani Role of a novel PH-kinase domain interface in PKB/Akt regulation: structural mechanism for allosteric inhibition PLoS Biol. 7 2009 e17
-
(2009)
PLoS Biol.
, vol.7
, pp. 17
-
-
Calleja, V.1
Laguerre, M.2
Parker, P.J.3
Larijani, B.4
-
34
-
-
34548743475
-
Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development
-
J. Ursini-Siegel, A.B. Rajput, H. Lu, V. Sanguin-Gendreau, D. Zuo, V. Papavasiliou, C. Lavoie, J. Turpin, K. Cianflone, D.G. Huntsman, and W.J. Muller Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development Mol. Cell. Biol. 27 2007 6361 6371
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 6361-6371
-
-
Ursini-Siegel, J.1
Rajput, A.B.2
Lu, H.3
Sanguin-Gendreau, V.4
Zuo, D.5
Papavasiliou, V.6
Lavoie, C.7
Turpin, J.8
Cianflone, K.9
Huntsman, D.G.10
Muller, W.J.11
-
35
-
-
21244435590
-
Novel small molecule inhibitors of 3-phosphoinositide- dependent kinase-1
-
R.I. Feldman, J.M. Wu, M.A. Polokoff, M.J. Kochanny, H. Dinter, D. Zhu, S.L. Biroc, B. Alicke, J. Bryant, S. Yuan, B.O. Buckman, D. Lentz, M. Ferrer, M. Whitlow, M. Adler, S. Finster, Z. Chang, and D.O. Arnaiz Novel small molecule inhibitors of 3-phosphoinositide- dependent kinase-1 J. Biol. Chem. 280 2005 19867 19874
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 19867-19874
-
-
Feldman, R.I.1
Wu, J.M.2
Polokoff, M.A.3
Kochanny, M.J.4
Dinter, H.5
Zhu, D.6
Biroc, S.L.7
Alicke, B.8
Bryant, J.9
Yuan, S.10
Buckman, B.O.11
Lentz, D.12
Ferrer, M.13
Whitlow, M.14
Adler, M.15
Finster, S.16
Chang, Z.17
Arnaiz, D.O.18
-
36
-
-
67650312583
-
Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)
-
J.M. García-Martínez, J. Moran, R.G. Clarke, A. Gray, S.C. Cosulich, C.M. Chresta, and D.R. Alessi Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR) Biochem. J. 421 2009 29 42
-
(2009)
Biochem. J.
, vol.421
, pp. 29-42
-
-
García-Martínez, J.M.1
Moran, J.2
Clarke, R.G.3
Gray, A.4
Cosulich, S.C.5
Chresta, C.M.6
Alessi, D.R.7
-
37
-
-
33744924482
-
Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441
-
Y. Zhao, H.D. Thomas, M.A. Batey, I.G. Cowell, C.J. Richardson, R.J. Griffin, A.H. Calvert, D.R. Newell, G.C. Smith, and N.J. Curtin Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441 Cancer Res. 66 2006 5354 5362
-
(2006)
Cancer Res.
, vol.66
, pp. 5354-5362
-
-
Zhao, Y.1
Thomas, H.D.2
Batey, M.A.3
Cowell, I.G.4
Richardson, C.J.5
Griffin, R.J.6
Calvert, A.H.7
Newell, D.R.8
Smith, G.C.9
Curtin, N.J.10
-
38
-
-
31544439674
-
Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival
-
A.A. Troussard, P.C. McDonald, E.D. Wederell, N.M. Mawji, N.R. Filipenko, K.A. Gelmon, J.E. Kucab, S.E. Dunn, J.T. Emerman, M.B. Bally, and S. Dedhar Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival Cancer Res. 66 2006 393 403
-
(2006)
Cancer Res.
, vol.66
, pp. 393-403
-
-
Troussard, A.A.1
McDonald, P.C.2
Wederell, E.D.3
Mawji, N.M.4
Filipenko, N.R.5
Gelmon, K.A.6
Kucab, J.E.7
Dunn, S.E.8
Emerman, J.T.9
Bally, M.B.10
Dedhar, S.11
-
39
-
-
74049103772
-
QLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatment outcomes in an orthotopic breast cancer model
-
J. Kalra, C. Warburton, K. Fang, L. Edwards, T. Daynard, D. Waterhouse, W. Dragowska, B.W. Sutherland, S. Dedhar, K. Gelmon, and M. Bally QLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatment outcomes in an orthotopic breast cancer model Breast Cancer Res. 11 2009 R25
-
(2009)
Breast Cancer Res.
, vol.11
, pp. 25
-
-
Kalra, J.1
Warburton, C.2
Fang, K.3
Edwards, L.4
Daynard, T.5
Waterhouse, D.6
Dragowska, W.7
Sutherland, B.W.8
Dedhar, S.9
Gelmon, K.10
Bally, M.11
-
40
-
-
78650969051
-
Differential roles of internal and terminal double bonds in docosahexaenoic acid: Comparative study of cytotoxicity of polyunsaturated fatty acids to HT-29 human colorectal tumor cell line
-
S.B. Sato, S. Sato, J. Kawamoto, and T. Kurihara Differential roles of internal and terminal double bonds in docosahexaenoic acid: Comparative study of cytotoxicity of polyunsaturated fatty acids to HT-29 human colorectal tumor cell line Prostaglandins Leukot. Essent. Fatty Acids 84 2011 31 37
-
(2011)
Prostaglandins Leukot. Essent. Fatty Acids
, vol.84
, pp. 31-37
-
-
Sato, S.B.1
Sato, S.2
Kawamoto, J.3
Kurihara, T.4
-
42
-
-
0031275070
-
Changes in hydrolysis specificities of lipase from Rhizomucor miehei to polyunsaturated fatty acyl esters in different aggregation states
-
Y. Kosugi, C. Quinglong, K. Kanazawa, and H. Nakanishi Changes in hydrolysis specificities of lipase from Rhizomucor miehei to polyunsaturated fatty acyl esters in different aggregation states J. Am. Oil Chem. Soc. 74 1997 1395 1399
-
(1997)
J. Am. Oil Chem. Soc.
, vol.74
, pp. 1395-1399
-
-
Kosugi, Y.1
Quinglong, C.2
Kanazawa, K.3
Nakanishi, H.4
-
43
-
-
58149161720
-
PPARgamma, PTEN, and the fight against cancer
-
R.E. Teresi, and K.A. Waite PPARgamma, PTEN, and the fight against cancer PPAR Res. 2008 2008 932632
-
(2008)
PPAR Res.
, vol.2008
, pp. 932632
-
-
Teresi, R.E.1
Waite, K.A.2
-
44
-
-
34548159221
-
Akt activation by arachidonic acid metabolism occurs via oxidation and inactivation of PTEN tumor suppressor
-
T.M. Covey, K. Edes, and F.A. Fitzpatrick Akt activation by arachidonic acid metabolism occurs via oxidation and inactivation of PTEN tumor suppressor Oncogene 26 2007 5784 5792
-
(2007)
Oncogene
, vol.26
, pp. 5784-5792
-
-
Covey, T.M.1
Edes, K.2
Fitzpatrick, F.A.3
-
45
-
-
0042175375
-
Multiple signal pathways are involved in the mitogenic effect of 5(S)-HETE in human pancreatic cancer
-
X.Z. Ding, W.G. Tong, and T.E. Adrian Multiple signal pathways are involved in the mitogenic effect of 5(S)-HETE in human pancreatic cancer Oncology 65 2003 285 294
-
(2003)
Oncology
, vol.65
, pp. 285-294
-
-
Ding, X.Z.1
Tong, W.G.2
Adrian, T.E.3
-
46
-
-
80052275615
-
PI3K/Akt signaling requires spatial compartmentalization in plasma membrane microdomains
-
X. Gao, P.R. Lowry, X. Zhou, C. Depry, Z. Wei, G.W. Wong, and J. Zhang PI3K/Akt signaling requires spatial compartmentalization in plasma membrane microdomains Proc. Natl. Acad. Sci. U. S. A. 108 2011 14509 14514
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 14509-14514
-
-
Gao, X.1
Lowry, P.R.2
Zhou, X.3
Depry, C.4
Wei, Z.5
Wong, G.W.6
Zhang, J.7
-
47
-
-
63749117393
-
TORC2 plasma membrane localization is essential for cell viability and restricted to a distinct domain
-
D. Berchtold, and T.C. Walther TORC2 plasma membrane localization is essential for cell viability and restricted to a distinct domain Mol. Biol. Cell 20 2009 1565 1575
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1565-1575
-
-
Berchtold, D.1
Walther, T.C.2
-
48
-
-
53149083731
-
Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells
-
C. Partovian, R. Ju, Z.W. Zhuang, K.A. Martin, and M. Simons Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells Mol. Cell 32 2008 140 149
-
(2008)
Mol. Cell
, vol.32
, pp. 140-149
-
-
Partovian, C.1
Ju, R.2
Zhuang, Z.W.3
Martin, K.A.4
Simons, M.5
-
49
-
-
0038496905
-
Novel localization of the DNA-PK complex in lipid rafts: A putative role in the signal transduction pathway of the ionizing radiation response
-
H. Lucero, D. Gae, and G.E. Taccioli Novel localization of the DNA-PK complex in lipid rafts: a putative role in the signal transduction pathway of the ionizing radiation response J. Biol. Chem. 278 2003 22136 22143
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 22136-22143
-
-
Lucero, H.1
Gae, D.2
Taccioli, G.E.3
-
50
-
-
33644848599
-
ILK, PINCH and parvin: The tIPP of integrin signaling
-
K.R. Legate, E. Montañez, O. Kudlacek, and R. Fässler ILK, PINCH and parvin: the tIPP of integrin signaling Nat. Rev. Mol. Cell Biol. 7 2006 20 31
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 20-31
-
-
Legate, K.R.1
Montañez, E.2
Kudlacek, O.3
Fässler, R.4
-
51
-
-
75349083246
-
Molecular species of phosphatidylinositol-cycle intermediates in the endoplasmic reticulum and plasma membrane
-
Y.V. Shulga, D.S. Myers, P.T. Ivanova, S.B. Milne, H.A. Brown, M.K. Topham, and R.M. Epand Molecular species of phosphatidylinositol-cycle intermediates in the endoplasmic reticulum and plasma membrane Biochemistry 49 2010 312 317
-
(2010)
Biochemistry
, vol.49
, pp. 312-317
-
-
Shulga, Y.V.1
Myers, D.S.2
Ivanova, P.T.3
Milne, S.B.4
Brown, H.A.5
Topham, M.K.6
Epand, R.M.7
-
53
-
-
67349142556
-
Mammalian diacylglycerol kinases: Molecular interactions and biological functions of selected isoforms
-
M.K. Topham, and R.M. Epand Mammalian diacylglycerol kinases: molecular interactions and biological functions of selected isoforms Biochim. Biophys. Acta 1790 2009 416 424
-
(2009)
Biochim. Biophys. Acta
, vol.1790
, pp. 416-424
-
-
Topham, M.K.1
Epand, R.M.2
-
54
-
-
62849111751
-
Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: Competition with rapamycin
-
A. Toschi, E. Lee, L. Xu, A. Garcia, N. Gadir, and D.A. Foster Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin Mol. Cell. Biol. 29 2009 1411 1420
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 1411-1420
-
-
Toschi, A.1
Lee, E.2
Xu, L.3
Garcia, A.4
Gadir, N.5
Foster, D.A.6
-
55
-
-
75049085322
-
Subgram daily supplementation with docosahexaenoic acid protects low-density lipoproteins from oxidation in healthy men
-
C. Calzada, R. Colas, N. Guillot, M. Guichardant, M. Laville, E. Véricel, and M. Lagarde Subgram daily supplementation with docosahexaenoic acid protects low-density lipoproteins from oxidation in healthy men Atherosclerosis 208 2010 467 472
-
(2010)
Atherosclerosis
, vol.208
, pp. 467-472
-
-
Calzada, C.1
Colas, R.2
Guillot, N.3
Guichardant, M.4
Laville, M.5
Véricel, E.6
Lagarde, M.7
|