Plekhh2, a novel podocyte protein downregulated in human focal segmental glomerulosclerosis, is involved in matrix adhesion and actin dynamics

Kidney International

Volumn 82, Issue 10, 2012, Pages 1071-1083

  Perisic, Ljubica ^a   Lal, Mark ^a   Hulkko, Jenny ^a   Hultenby, Kjell ^a   Önfelt, Björn ^b   Sun, Ying ^a   Dunér, Fredrik ^a   Patrakka, Jaakko ^a   Betsholtz, Christer ^a   Uhlen, Mathias ^b   Brismar, Hjalmar ^b   Tryggvason, Karl ^a   Wernerson, Annika ^a   Pikkarainen, Timo ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

cell biology and structure; cell matrix interactions; cytoskeleton; podocyte; protein interaction

Indexed keywords

ACTIN; CELL PROTEIN; FOCAL ADHESION KINASE; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PLECKSTRIN HOMOLOGY DOMAIN CONTAINING FAMILY H MEMBER 2 PROTEIN; PROTEIN HIC 5; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL ADHESION; CONTROLLED STUDY; DEPOLYMERIZATION; DOWN REGULATION; EXTRACELLULAR MATRIX; FERM DOMAIN; FOCAL GLOMERULOSCLEROSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY BIOPSY; LAMELLIPODIUM; MOLECULAR PATHOLOGY; MOUSE; MYTH4 DOMAIN; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS;

ACTIN CYTOSKELETON; ACTINS; ANIMALS; BINDING SITES; BIOPSY; CASE-CONTROL STUDIES; CELL-MATRIX JUNCTIONS; CERCOPITHECUS AETHIOPS; CHO CELLS; COS CELLS; CRICETINAE; CRICETULUS; CYTOSKELETAL PROTEINS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; DOWN-REGULATION; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIM DOMAIN PROTEINS; MICE; PHOSPHATIDYLINOSITOL PHOSPHATES; PODOCYTES; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, SECONDARY; PROTEIN TRANSPORT; PSEUDOPODIA; SEQUENCE ANALYSIS, PROTEIN; TRANSFECTION; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 84868562645     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2012.252     Document Type: Article

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