Involvement of Hic-5 in platelet activation: Integrin αIIbβ3-dependent tyrosine phosphorylation and association with proline-rich tyrosine kinase 2

Biochemical Journal

Volumn 355, Issue 3, 2001, Pages 691-697

  Osada, Makoto ^a   Ohmori, Tsukasa ^a   Yatomi, Yutaka ^a   Satoh, Kaneo ^a   Hosogaya, Shigerni ^a   Ozaki, Yukio ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Adhesion; Focal adhesion kinase; Protein kinase C

Indexed keywords

ADHESION; AGGLOMERATION; CELLS; COLLAGEN; MEMBRANES; PROTEINS;

PHOSPHORYLATION;

ENZYMES;

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; COLLAGEN; FIBRINOGEN; FOCAL ADHESION KINASE; INTEGRIN; PAXILLIN; PROLINE; PROTEIN; PROTEIN HIC 5; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; THROMBIN; THROMBOXANE A2; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; CYTOSOL; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION;

EID: 0035340492     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3550691     Document Type: Article

References (38)

1. 1 Watson, S. P. (1999) Collagen receptor-signaling in platelets and megakaryocytes. Thromb. Haemost. 82, 365-376
2. 2 Jackson, S. P., Schoenwaelder, S. M., Yuan, Y., Salem, H. H. and-Cooray, P. (1996) Non-receptor protein tyrosine kinases and phosphatases in human platelets. Thromb. Haemost. 76, 640-650.
3. 3 Levy-Toledano, S., Gallet, C., Nadal, F., Bryckaert, M., Maclouf, J. and Rosa, J. P. (1997) Phosphorylation and dephosphorylation mechanisms in platelet function: a tightly-regulated balance. Thromb. Haemost. 78, 226-233
4. 4 Shattil, S. J., Kashiwagi, H. and Pampori, N. (1998) Integrin signaling: the platelet paradigm. Blood 81, 2645-2657
5. 5 Ferrell, J. E. and Martin, G. S. (1989) Tyrosine-specific protein phosphorylation is regulated by glycoprotein IIb-IIIa in platelets. Proc. Natl. Acad. Sci. U.S.A. 86, 2234-2238
6. 6 Ohmori, T., Yatomi, Y., Asazuma, N., Satoh, K. and Ozaki, Y. (1999) Suppression of protein kinase C is associated with inhibition of PYK2 tyrosine phosphorylation and enhancement of PYK2 interaction with Sre in thrombin-activated platelets. Thromb. Res. 93, 291-298
7. 7 Ohmori, T., Yatomi, Y., Asazuma, N., Satoh, K. and Ozaki, Y. (2000) Proline-rich tyrosine kinase 2 involvement in platelet activation: tyrosine phosphorylation mostly dependent on αIIbβ3 integrln and protein kinase C, translocation to the cytoskeleton, and association with Shc through Grb2, Biochem, J. 347, 561-569
8. 8 Shibanuma, M., Mashimo, J., Kuroki, T. and Nose, K. (1994) Characterization of the TGFβ 1-inducible hlc-5 gene that encodes a putative novel zinc finger protein and its possible involvement in cellular senescence. J. Biol. Chem. 269, 26767-26774
9. 9 Matsuya, M., Sasaki, H., Aoto, H., Mitaka, T., Nagura, K., Ohba, T., Ishino, M., Takahashi, S., Suzuki, R. and Sasaki, T. (1998) Cell adhesion kinase β forms a complex with a new member, Hlc-5, of proteins localized at focal adhesions. J. Biol. Chem. 273, 1003-1014
10. 10 Thomas, S. M., Hagel, M. and Turner, C. E. (1999) Characterization of a focal adhesion protein, Hlc-5, that shares extensive homology with paxillin. J. Cell. Sci. 112, 181-190
11. 11 Zhang, J., Zhang, L. X., Meltzer, P. S., Barrett, J. C. and Trent, J. M. (2000) Molecular cloning of human Hlc-5, a potential regulator involved in signal transduction and cellular senescence. Mol. Carcinogen. 27, 177-183
12. 12 Fujita, H., Kamiguchi, K., Cho, D., Shibanuma, M., Morimoto, C. and Tachibana, K. (1998) Interaction of Hlc-5, A senescence-related protein, with focal adhesion kinase. J. Biol. Chem. 273, 26516-26521
13. 13 Law, D. A., DeGuzman, F. R., Heiser, P., Ministri-Madrid, K., Killeen, N. and Phillips, D. R. (1999) Integrin cytoplasmic tyrosine motif is required for outside-in αIIbβ3 signalling and platelet function. Nature (London) 401, 808-811
14. 14 Hagmann, J., Grob, M., Welman, A., van Willigen, G. and Burger, M. M. (1998) Recruitment of the LIM protein hlc-5 to focal contacts of human platelets. J. Cell Sci. 111, 2181-2188
15. 3yk in human platelets. J. Biol. Chem. 70, 15119-15124
16. 16 Hisano, N., Yatomi, Y., Satoh, K., Akimoto, S., Mitsumata, M., Fujino, M. A. and Ozaki, Y. (1999) Induction and suppression of endothelial cell apoptosis by sphingolipids: a possible in vitro model for cell-cell interactions between platelets and endothelial cells. Blood 93, 4293-4299
17. 17 Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254
18. ras GTPase activating protein with the membrane skeleton. J. Biol. Chem. 268, 25973-25984
19. 19 Ogura, M., Morishima, Y., Ohno, R., Kato, Y., Hirabayashi, N., Nagura, H. and Saito, H. (1985) Establishment of a novel human megakaryoblastic leukemia cell line, MEG-01, with positive Philadelphia chromosome. Blood 66, 1384-1392
20. 20 Ishino, M., Aoto, H., Sasaki, H., Suzuki, R. and Sasaki, T. (2000) Phosphorylation of Hlc-5 at tyrosine 60 by CAKβ and Fyn. FEBS Lett. 474, 179-183
21. 21 Mazaki, Y., Hashimoto, S. and Sabe, H. (1997) Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins. J. Biol. Chem. 272, 7437-7444
22. 22 Brass, L. F., Manning, D. R., Cichowski, K. and Abrams, C. S. (1997) Signaling through G proteins in platelets: to the integrins and beyond. Thromb. Haemost. 78, 581-589
23. 23 Ozaki, K., Oda, A., Wakao, H., Rhodes, J., Druker, B. J., Ishida, A., Wakul, M., Okamoto, S., Morita, K., Handa, M. et al. (1998) Thrombopoletin induces association of Crkl with STAT5 but not STATS in human platelets. Blood 92, 4652-4662
24. 24 Oda, A., Miyakawa, Y., Druker, B. J., Ozaki, K., Ohashi, H., Kato, T., Miyazaki, H., Handa, M., Ikebuchi, K. and Ikeda, Y. (1999) Thrombopoletin-induced signal transduction and potentiation of platelet activation. Thromb. Haemost. 82, 377-384
25. 25 Asazuma, N., Ozaki, Y., Satoh, K., Yatomi, Y., Handa, M., Fujimura, Y., Miura, S. and Kume, S. (1997) Glycoprotein Ib-von Willebrand factor interactions activate tyrosine kinases in human platelets. Blood 90, 4789-4798
26. 26 Nishizuka, Y. (1988) The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature (London) 334, 661-665
27. 27 Tamaoki, T. (1991) Use and specificity of staurasporine, UCN-01, and calphostin C as protein kinase inhibitors. Methods Enzymol. 201, 340-347
28. 28 Wilkinson, S. E., Parker, P. J. and Nixon, J. S. (1993) Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. Biochem. J. 294, 335-337
29. syk protein tyrosine kinase by platelet integrin αIIbβ3. EMBO J. 16, 6414-6425
30. 30 Turner, C. E. (1998) Paxillin. Int. J. Biochem. Cell. Biol. 30, 955-959
31. 31 Ishino, K., Kaneyama, Jr., Shibanuma, M. and Nose, K. (2000) Specific decrease in the level of Hlc-5, a focal adhesion protein, during immortalization of mouse embryonic fibrablasts, and its association with focal adhesion kinase. J. Cell. Biochem. 76, 411-419
32. 32 Shibanuma, M. and Nose, K. (1998) Forced expression of hlc-5, a senescence-related gene, potentiates a differentiation process of RCT-1 cells induced by retinoic acid. Int. J. Biochem. Cell. Biol. 30, 39-45
33. 33 Schlaepfer, D. D., Hauck, C. R. and Sieg, D. J. (1999) Signaling through focal adhesion kinase. Prog. Biophys. Mol. Biol. 71, 435-478
34. 34 Block, K. L. and Ponez, M. (1998) Platelet glycoprotein IIb gene expression as a model of megakaryocyte-specific expression. Stem Cells 13, 135-145
35. 35 Rozengurt, E. (1998) Signal transduction pathways in the mitogenic response to G protein-coupled neuropeptide receptor agonists. J. Cell. Physlol. 177, 507-517
36. FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol. Cell. Biol. 15, 2635-2645
37. 37 Avraham, S. and Avraham, H. (1997) Characterization of the novel focal adhesion kinase RAFTK in hematopoietic cells. Leuk. Lymphoma 27, 247-256
38. 38 Schaller, M. D. and Sasaki, T. (1997) Differential signaling by the focal adhesion kinase and cell adhesion kinase β. J. Biol. Chem. 272, 25319-25325