Does pharmacodynamic interaction of nonenzymatic antioxidants modify response to antioxidant therapy in the process of atherosclerosis?

Journal of Cardiovascular Pharmacology and Therapeutics

Volumn 17, Issue 4, 2012, Pages 366-372

  Yiannakopoulou, Eugenia Ch ^a  

^a UNIVERSITY OF WEST ATTICA   (Greece)

Author keywords

additive effect; antagonistic effect; antioxidants; atherosclerosis; interaction; synergistic effect

Indexed keywords

ACEROLA CHERRY EXTRACT; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; AVENANTHRAMIDE DERIVATIVE; BETA CAROTENE; CAFFEIC ACID DERIVATIVE; CARNOSIC ACID; CATECHIN; FERULIC ACID; GARLIC ACID; GARLIC EXTRACT; GLABRIDIN; HESPERIDIN; LOW DENSITY LIPOPROTEIN; LYCOPENE; PHENOL DERIVATIVE; PHYTOESTROGEN; PLACEBO; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; POLYPHENOL; POLYSACCHARIDE; RED WINE EXTRACT; RETINOL; ROSMARINIC ACID; RUTOSIDE; TERPINENE; TOCOPHEROL; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALFALFA; ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; DISEASE COURSE; DRUG EFFECT; DRUG FATALITY; DRUG MECHANISM; DRUG POTENTIATION; ECHINACEA PURPUREA; HEART INFARCTION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; ISCHEMIC HEART DISEASE; LIPID PEROXIDATION; LUNG CANCER; NONHUMAN; OLEA EUROPEA; OLIVE TREE; PRIORITY JOURNAL; PUBLICATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); RED WINE; SOYBEAN; SYSTEMATIC REVIEW; TREATMENT RESPONSE; VITAMIN SUPPLEMENTATION;

ANIMALS; ANTIOXIDANTS; ATHEROSCLEROSIS; COMBINED MODALITY THERAPY; DIETARY SUPPLEMENTS; DISEASE PROGRESSION; EVIDENCE-BASED MEDICINE; FOOD-DRUG INTERACTIONS; HUMANS; OXIDATIVE STRESS;

EID: 84868559944     PISSN: 10742484     EISSN: 19404034     Source Type: Journal    
DOI: 10.1177/1074248412447109     Document Type: Article

References (44)

1. Mizuno Y, Jacob RF, Mason RP. Inflammation and the development of atherosclerosis. J Atheroscler Thromb. 2011 ; 18 (5). 351-358
2. Aguirre R, May JM. Inflammation in the vascular bed: importance of vitamin C. Pharmacol Ther. 2008 ; 119 (1). 96-103
3. Bonomini F, Tengattini S, Fabiano A, Bianchi R, Rezzani R. Atherosclerosis and oxidative stress. Histol Histopathol. 2008 ; 23 (3). 381-390
4. Lushchak VI. Adaptive response to oxidative stress: bacteria, fungi, plants and animals. Comp Biochem Physiol C Toxicol Pharmacol. 2011 ; 153 (2). 175-190
5. Klatt P, Lamas S. Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stress. Eur J Biochem. 2000 ; 267 (16). 4928-4944
6. Mitra S, Deshmukh A, Sachdeva R, Lu J, Mehta JL. Oxidized low-density lipoprotein and atherosclerosis implications in antioxidant therapy. Am J Med Sci. 2011 ; 342 (2). 135-142
7. Yiannakopoulou ECh, Tyligada E. Protective effect of salicylates against hydrogen peroxide stress in yeast. J Appl Microbiol. 2009 ; 106 (3). 903-908
8. Carr AC, Zhu BZ, Frei B. Potential antiatherogenic mechanisms of ascorbate (vitamin C) and alpha-tocopherol (vitamin E). Circ Res. 2000 ; 87 (5). 349-354
9. Sahyoun NR, Jacques PF, Russell RM. Carotenoids, vitamins C and E, and mortality in an elderly population. Am J Epidemiol. 1996 ; 144 (5). 501-511
10. Muntwyler J, Hennekens CH, Manson JE, Buring JE, Gaziano JM. Vitamin supplement use in a low-risk population of US male physicians and subsequent cardiovascular mortality. Arch Intern Med. 2002 ; 162 (13). 1472-1476
11. Joshipura KJ, Hu FB, Manson JE, et al. The effect of fruit and vegetable intake on risk for coronary heart disease. Ann Intern Med. 2001 ; 134 (12). 1106-1114
12. Zureik M, Galan P, Bertrais S, et al. Effects of long-term daily low-dose supplementation with antioxidant vitamins and minerals on structure and function of large arteries. Atheroscler Thromb Vasc Biol. 2004 ; 24 (8). 1485-1491
13. Sesso HD, Buring JE, Christen WG, et al. Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA. 2008 ; 300 (18). 2123-2133
14. Trombino S, Serini S, Di Nicuolo F, et al. Antioxidant effect of ferulic acid in isolated membranes and intact cells: synergistic interactions with alpha-tocopherol, beta-carotene, and ascorbic acid. J Agric Food Chem. 2004 ; 52 (8). 2411-2420
15. Negre-Salvayre A, Mabile L, Delchambre A, Salvayre R. Alpha-tocopherol, ascorbic acid and rutin inhibit synergistically the copper-promoted LDL oxidation and the cytotoxicity of oxidized LDL to cultured endothelial cells. Biol Trace Elem Res. 1995 ; 47 (1-3). 81-91
16. Dobreanu M, Mody E. Influence of natural antioxidants on in vitro lipoprotein oxidation. Rom J Intern Med. 1997 ; 35 (1-4). 55-62
17. Fuhrman B, Volkova N, Rosenblat M, Aviram M. Lycopene synergistically inhibits LDL oxidation in combination with vitamin E, glabridin, rosmarinic acid, carnosic acid or garlic. Antioxid Redox Signal. 2000 ; 2 (3). 491-506
18. Hwang J, Hodis HN, Sevanian A. Soy and alfalfa phytoestrogen extracts become potent low density lipoprotein antioxidants in the presence of acerola cherry extract. J Agric Food Chem. 2001 ; 49 (1). 308-314
19. Ivanov C, Carr AC, Frei B. Red wine antioxidants bind to human lipoproteins and protect them from metal-ion dependent and independent oxidation. J Agric Food Chem. 2001 ; 49 (9). 4442-4449
20. Shafiee M, Carbonneau MA, d'Huart JB, Descomps B, Leger CL. Synergistic antioxidant properties of phenolics from natural origin towards low density lipoproteins dependent on the oxidation system. J Med Food. 2002 ; 5 (2). 69-78
21. Milde J, Elstner EF, Grassman J. Synergistic effects of low density lipoprotein oxidation by rutin, gamma-terpinene and ascorbic acid. Phytomedicine. 2004 ; 11 (2-3). 105-113
22. Briante R, Febbraio F, Nucci R. Antioxidant/prooxidant effects of dietary non flavonoid phenols on the Cu induced oxidation of human low density lipoprotein (LDL). Chem Biodivers. 2004 ; 1 (11). 1716-1719
23. Chen CY, Milbury PE, Kwak HK, Collins FW, Samuel P, Blumberg GB. Avenanthramides and phenolic acids from oats are bioavailable and act synergistically with vitamin C to enhance hamster and human LDL resistance to oxidation. J Nutr. 2004 ; 134 (6). 1459-1466
24. Dalby-Brown L, Barsett H, Landbo AK, Meyer AS, Mølgaard P. Synergistic antioxidative effects of alkamides, caffeic acid derivatives, and polysaccharide fractions from Echinacea purpurea on in vitro oxidation of human low-density lipoproteins. J Agric Food Chem. 2005 ; 53 (24). 9413-9423
25. Cirico TL, Omaye ST. Additive or synergistic effects of phenolic compounds on human low density lipoprotein oxidation. Food Chem Toxicol. 2006 ; 44 (4). 510-516
26. Milde J, Elstner E, Grassman J. Synergistic effects of phenolics and carotenoids on human low density lipoprotein oxidation. Mol Nutr Food Res. 2007 ; 51 (8). 956-961
27. Ulrich-Merzenich G, Metzner C, Shiermeyer B, Vetter H. Vitamin C and vitamin E antagonistically modulate human vascular endothelial and smooth muscle cell DNA synthesis and proliferation. Eur J Nutr. 2002 ; 41 (1). 27-34
28. Negre-Salvayre A, Affany A, Hariton C, Salvayre R. Additional lipoperoxidant activities of alpha tocopherol and ascorbic acid on membrane-like systems are potentiated by rutin. Pharmacology. 1991 ; 42 (5). 262-272
29. Zhang P, Omay SP. Antioxidant and prooxidant roles for beta-carotene, alpha-tocopherol and ascorbic acid in human lung cells. Toxicol In Vitro. 2001 ; 15 (1). 13-24
30. Schmidt A, Salvayre R, Delchambre A, Negre-Salvayre A. Prevention by alpha-tocopherol and rutin of glutathione and ATP depletion induced by oxidized LDL in cultured endothelial cells. Br J Pharmacol. 1995 ; 116 (3). 1985-1990
31. Sabharwal AK, May JM. Alpha-lipoic acid and ascorbate prevent LDL oxidation and oxidant stress in endothelial cells. Mol Cell Biochem. 2008 ; 309 (1-2). 125-132
32. Rapola JM, Virtamo J, Ripatti S, et al. Randomized trial of alpha tocopherol and beta-carotene supplements on incidence of major coronary events in men with previous myocardial infarction. Lancet. 1997 ; 349 (9067). 1715-1720
33. Salonen JT, Nyyssönen K, Salonen R, et al. Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) study: a randomized trial of the effect of vitamins E and C on 3-year progression of carotid atherosclerosis. J Intern Med. 2000 ; 248 (5). 377-386
34. Huang HY, Appel LJ, Croft KD, Miller ER, Mori TA, Pudey IB. Effects of vitamin C and vitamin E on in vivo lipid peroxidation: results of a randomized controlled trial. Am J Clin Nutr. 2002 ; 76 (3). 549-555
35. Salonen RM, Nyyssönen K, Kaikkonen J, et al. Antioxidant Supplementation in Atherosclerosis Prevention Study. Six-year effect of combined vitamin C and E supplementation on atherosclerotic progression: the Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) Study. Circulation. 2003 ; 107 (7). 947-953
36. Chan AC. Partners in defense, vitamin E and vitamin C. Can J Physiol Pharmacol. 1993 ; 71 (9). 725-731
37. Kagan VE, Serbinova EA, Forte T, Scita G, Packer L. Recycling of vitamin E in human low density lipoproteins. J Lipid Res. 1992 ; 33 (3). 385-397
38. Keaney JF, Simon DI, Freedman JE. Vitamin E and vascular homeostasis: implications for atherosclerosis. FASEB J. 1999 ; 13 (9). 965-975
39. Kinlay S, Fang JC, Hikita H, et al. Plasma alpha-tocopherol and coronary endothelium-dependent vasodilator function. Circulation. 1999 ; 100 (3). 219-221
40. Yasunari K, Kohno M, Kano H, Yokokawa K, Minami M, Yoshikawa J. Antioxidants improve impaired insulin-mediated glucose uptake and prevent migration and proliferation of cultured rabbit coronary smooth muscle cells induced by high glucose. Circulation. 1999 ; 99 (10). 1370-1378
41. Eckert RL, Crish JF, Efimova T, Balasubramanian S. Opposing action of curcumin and green tea polyphenol in human ceratocytes. Mol Nutr Food Res. 2006 ; 50 (2). 123-129
42. Murakami A, Takahashi D, Koshimizu K, Ohigashi H. Synergistic suppression of superoxide and nitric oxide generation from inflammatory cells by combined food factors. Mutat Res. 2003 ;: 523 151-524 161
43. Yiannakopoulou ECh, Tiligada E. Antagonistic action of antioxidants during the oxidative stress response in eukaryotic cells. FEBS J. 2008 ; 275 (Suppl 1). 282
44. Omenn GS, Goodman GE, Thornquist MD, et al. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med. 1996 ; 334 (18). 1150-1155