메뉴 건너뛰기




Volumn 39, Issue 10, 2012, Pages 9299-9306

Effect of small interfering RNA transfection on FAK and DLC1 mRNA expression in OVCAR-3

Author keywords

DLC1; FAK; OVCAR 3; pGFP siCon DLC1 vector; pGFP siFAK DLC1 vector; siRNA; Transfection

Indexed keywords

CASPASE 3; CASPASE 9; MESSENGER RNA; ONCOPROTEIN; PROTEIN DLC1; PROTEIN FAK; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84868545438     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-1724-7     Document Type: Article
Times cited : (7)

References (44)
  • 1
    • 42249094731 scopus 로고    scopus 로고
    • Pharmaceutical management of ovarian cancer: Current status
    • Markman M (2008) Pharmaceutical management of ovarian cancer: current status. Drugs 68:771-789
    • (2008) Drugs , vol.68 , pp. 771-789
    • Markman, M.1
  • 3
    • 0043240182 scopus 로고    scopus 로고
    • Ovarian cancer: Strategies for overcoming resistance to chemotherapy
    • Agarwal R, Kaye SB (2003) Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat Rev Cancer 3(7):502
    • (2003) Nat Rev Cancer , vol.3 , Issue.7 , pp. 502
    • Agarwal, R.1    Kaye, S.B.2
  • 4
    • 11244261320 scopus 로고    scopus 로고
    • Reversing resistance to targeted therapy
    • Vidal L, Attard G, Kaye S, De Bono J (2004) Reversing resistance to targeted therapy. J Chemother 16(Suppl 4):7-12
    • (2004) J Chemother , vol.16 , Issue.SUPPL. 4 , pp. 7-12
    • Vidal, L.1    Attard, G.2    Kaye, S.3    De Bono, J.4
  • 5
    • 27944481777 scopus 로고    scopus 로고
    • Drug resistance in ovarian cancer: The emerging importance of gene transcription and spatio-temporal regulation of resistance
    • Richardson A, Kaye SB (2005) Drug resistance in ovarian cancer: the emerging importance of gene transcription and spatio-temporal regulation of resistance. Drug Resist Updat 8(5):311-321
    • (2005) Drug Resist Updat , vol.8 , Issue.5 , pp. 311-321
    • Richardson, A.1    Kaye, S.B.2
  • 6
    • 36849044732 scopus 로고    scopus 로고
    • Nonviral delivery of synthetic siRNAs in vivo
    • Akhtar S, Benter IF (2007) Nonviral delivery of synthetic siRNAs in vivo. J Clin Invest 117:3623-3632
    • (2007) J Clin Invest , vol.117 , pp. 3623-3632
    • Akhtar, S.1    Benter, I.F.2
  • 7
    • 34248682403 scopus 로고    scopus 로고
    • RNAi therapeutics: Principles, prospects and challenges
    • Aagaard L, Rossi JJ (2007) RNAi therapeutics: principles, prospects and challenges. Adv Drug Deliv Rev 59:75-86
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 75-86
    • Aagaard, L.1    Rossi, J.J.2
  • 8
    • 78449309070 scopus 로고    scopus 로고
    • Efficient and targeted delivery of siRNA in vivo
    • Shim MS, Kwon YJ (2010) Efficient and targeted delivery of siRNA in vivo. FEBS J 277:4814-4827
    • (2010) FEBS J , vol.277 , pp. 4814-4827
    • Shim, M.S.1    Kwon, Y.J.2
  • 9
    • 0017681196 scopus 로고
    • DNA sequencing with chain-terminating inhibitors
    • Sanger F, Nicklen S, Coulson AR (1977) DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74(12):5463-5467
    • (1977) Proc Natl Acad Sci USA , vol.74 , Issue.12 , pp. 5463-5467
    • Sanger, F.1    Nicklen, S.2    Coulson, A.R.3
  • 10
    • 0020959710 scopus 로고
    • Studies on transformation of Escherichia coli with plasmids
    • Hanahan D (1983) Studies on transformation of Escherichia coli with plasmids. J Mol Biol 166:557-580
    • (1983) J Mol Biol , vol.166 , pp. 557-580
    • Hanahan, D.1
  • 11
    • 19744368302 scopus 로고    scopus 로고
    • Cancer of the ovary
    • Cannistra SA (2004) Cancer of the ovary. N Engl J Med 351:2519-2529
    • (2004) N Engl J Med , vol.351 , pp. 2519-2529
    • Cannistra, S.A.1
  • 12
    • 1442278561 scopus 로고    scopus 로고
    • Restoration of DLC-1 gene expression induces apoptosis and inhibits both cell growth and tumorigenicity in human hepatocellular carcinoma cells
    • Zhou X, Thorgeirsson SS, Popescu NC (2004) Restoration of DLC-1 gene expression induces apoptosis and inhibits both cell growth and tumorigenicity in human hepatocellular carcinoma cells. Oncogene 23(6):1308-1313
    • (2004) Oncogene , vol.23 , Issue.6 , pp. 1308-1313
    • Zhou, X.1    Thorgeirsson, S.S.2    Popescu, N.C.3
  • 14
    • 33847073342 scopus 로고    scopus 로고
    • DLC-1, a GTPase-activating protein for Rho, is associated with cell proliferation, morphology, and migration in human hepatocellular carcinoma
    • Kim TY, Lee JW, Kim HP, Jong HS, Kim TY, Jung M, Bang YJ (2007) DLC-1, a GTPase-activating protein for Rho, is associated with cell proliferation, morphology, and migration in human hepatocellular carcinoma. Biochem Biophys Res Commun 355(1):72-77
    • (2007) Biochem Biophys Res Commun , vol.355 , Issue.1 , pp. 72-77
    • Kim, T.Y.1    Lee, J.W.2    Kim, H.P.3    Jong, H.S.4    Kim, T.Y.5    Jung, M.6    Bang, Y.J.7
  • 15
    • 55349116044 scopus 로고    scopus 로고
    • Deleted in liver cancer 1 controls cell migration through a Dia1-dependent signaling pathway
    • Holeiter G, Heering J, Erlmann P, Schmid S, Jahne R, Olayioye MA (2008) Deleted in liver cancer 1 controls cell migration through a Dia1-dependent signaling pathway. Cancer Res 68:8743-8751
    • (2008) Cancer Res , vol.68 , pp. 8743-8751
    • Holeiter, G.1    Heering, J.2    Erlmann, P.3    Schmid, S.4    Jahne, R.5    Olayioye, M.A.6
  • 16
    • 14944386960 scopus 로고    scopus 로고
    • Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesteroneregulated genes for ovarian cancer cells by gene profiling
    • Syed V, Mukherjee K, Lyons-Weiler J, Lau KM, Mashima T, Tsuruo T, Ho SM (2005) Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesteroneregulated genes for ovarian cancer cells by gene profiling. Oncogene 24:1774-1787
    • (2005) Oncogene , vol.24 , pp. 1774-1787
    • Syed, V.1    Mukherjee, K.2    Lyons-Weiler, J.3    Lau, K.M.4    Mashima, T.5    Tsuruo, T.6    Ho, S.M.7
  • 17
    • 79951578122 scopus 로고    scopus 로고
    • DLC-1 as a modulator of proliferation, apoptosis and migration in Burkitt's lymphoma cells
    • Feng MH, Huang B, Du ZG, Xu XP, Chen Z (2011) DLC-1 as a modulator of proliferation, apoptosis and migration in Burkitt's lymphoma cells. Mol Biol Rep 38:1915-1920
    • (2011) Mol Biol Rep , vol.38 , pp. 1915-1920
    • Feng, M.H.1    Huang, B.2    Du, Z.G.3    Xu, X.P.4    Chen, Z.5
  • 18
    • 68149125221 scopus 로고    scopus 로고
    • DNA profiling by array comparative genomic hybridization (CGH) of peripheral blood mononuclear cells (PBMC) and tumor tissue cell in non-small cell lung cancer (NSCLC)
    • Baik S-H, Jee B-K, Choi J-S, Yoon H-K, Lee K-H, Kim YH, Lim Y (2009) DNA profiling by array comparative genomic hybridization (CGH) of peripheral blood mononuclear cells (PBMC) and tumor tissue cell in non-small cell lung cancer (NSCLC). Mol Biol Rep 36:1767-1778
    • (2009) Mol Biol Rep , vol.36 , pp. 1767-1778
    • Baik, S.-H.1    Jee, B.-K.2    Choi, J.-S.3    Yoon, H.-K.4    Lee, K.-H.5    Kim, Y.H.6    Lim, Y.7
  • 20
    • 0034941053 scopus 로고    scopus 로고
    • PP 60 (c-src) and related tyrosine kinases: A role in the assembly and reorganization of matrix adhesions
    • Volberg T, Romer L, Zamir E, Geiger B (2001) pp 60 (c-src) and related tyrosine kinases: a role in the assembly and reorganization of matrix adhesions. J Cell Sci 114:2279-2289
    • (2001) J Cell Sci , vol.114 , pp. 2279-2289
    • Volberg, T.1    Romer, L.2    Zamir, E.3    Geiger, B.4
  • 21
    • 0032576547 scopus 로고    scopus 로고
    • Regulation of the cell cycle by focal adhesion kinase
    • Zhao JH, Reiske H, Guan JL (1998) Regulation of the cell cycle by focal adhesion kinase. J Cell Biol 143:1997-2008
    • (1998) J Cell Biol , vol.143 , pp. 1997-2008
    • Zhao, J.H.1    Reiske, H.2    Guan, J.L.3
  • 23
    • 84860344107 scopus 로고    scopus 로고
    • Chronic mechanical stress induces mucin 5AC expression in human bronchial epithelial cells through ERK dependent pathways
    • Li N, Li Q, Zhou XD, Kolosov VP, Perelman JM (2012) Chronic mechanical stress induces mucin 5AC expression in human bronchial epithelial cells through ERK dependent pathways. Mol Biol Rep 39:1019-1028
    • (2012) Mol Biol Rep , vol.39 , pp. 1019-1028
    • Li, N.1    Li, Q.2    Zhou, X.D.3    Kolosov, V.P.4    Perelman, J.M.5
  • 24
    • 66849094252 scopus 로고    scopus 로고
    • Applications of RNA interference in cancer therapeutics as a powerful tool for suppressing gene expression
    • He S, Zhang DC, Cheng F, Gong FH, Guo YN (2009) Applications of RNA interference in cancer therapeutics as a powerful tool for suppressing gene expression. Mol Biol Rep 36:2153-2163
    • (2009) Mol Biol Rep , vol.36 , pp. 2153-2163
    • He, S.1    Zhang, D.C.2    Cheng, F.3    Gong, F.H.4    Guo, Y.N.5
  • 26
    • 33746481375 scopus 로고    scopus 로고
    • Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model
    • Mitra SK, Lim ST, Chi A, Schlaepfer DD (2006) Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model. Oncogene 25:4429-4440
    • (2006) Oncogene , vol.25 , pp. 4429-4440
    • Mitra, S.K.1    Lim, S.T.2    Chi, A.3    Schlaepfer, D.D.4
  • 27
    • 19644388523 scopus 로고    scopus 로고
    • Requirement for focal adhesion kinase in the early phase of mammary adenocarcinoma lung metastasis formation
    • Van Nimwegen MJ, Verkoeijen S, Van Buren L, Burg D, Van De Water B (2005) Requirement for focal adhesion kinase in the early phase of mammary adenocarcinoma lung metastasis formation. Cancer Res 65:4698-4706
    • (2005) Cancer Res , vol.65 , pp. 4698-4706
    • Van Nimwegen, M.J.1    Verkoeijen, S.2    Van Buren, L.3    Burg, D.4    Van De Water, B.5
  • 28
    • 0035948579 scopus 로고    scopus 로고
    • Biochemical signals and biological responses elicited by the focal adhesion kinase
    • Schaller MD (2001) Biochemical signals and biological responses elicited by the focal adhesion kinase. Biochim Biophys Acta 1540:1-21
    • (2001) Biochim Biophys Acta , vol.1540 , pp. 1-21
    • Schaller, M.D.1
  • 30
    • 0033833068 scopus 로고    scopus 로고
    • Pyk2 and FAK differentially regulate progression of the cell cycle
    • Zhao J, Zheng C, Guan J (2000) Pyk2 and FAK differentially regulate progression of the cell cycle. J Cell Sci 113:3063-3072
    • (2000) J Cell Sci , vol.113 , pp. 3063-3072
    • Zhao, J.1    Zheng, C.2    Guan, J.3
  • 31
    • 0037424498 scopus 로고    scopus 로고
    • The role of focal adhesion kinasephosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression
    • Reif S, Lang A, Lindquist JN, Yata Y, Gabele E, Scanga A, Brenner DA, Rippe RA (2003) The role of focal adhesion kinasephosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression. J Biol Chem 278:8083-8090
    • (2003) J Biol Chem , vol.278 , pp. 8083-8090
    • Reif, S.1    Lang, A.2    Lindquist, J.N.3    Yata, Y.4    Gabele, E.5    Scanga, A.6    Brenner, D.A.7    Rippe, R.A.8
  • 32
    • 33847171545 scopus 로고    scopus 로고
    • Combinatorial activation of FAK and AKT by transforming growth factor-β1 confers an anoikis-resistant phenotype to myofibroblasts
    • Horowitz JC, Rogers DS, Sharma V, Vittal R, White ES, Cui Z, Thannickal VJ (2007) Combinatorial activation of FAK and AKT by transforming growth factor-β1 confers an anoikis-resistant phenotype to myofibroblasts. Cell Signal 19:761-771
    • (2007) Cell Signal , vol.19 , pp. 761-771
    • Horowitz, J.C.1    Rogers, D.S.2    Sharma, V.3    Vittal, R.4    White, E.S.5    Cui, Z.6    Thannickal, V.J.7
  • 34
    • 33847314539 scopus 로고    scopus 로고
    • The phosphatidyl inositol 3-kinase signaling network: Implications for human breast cancer
    • Dillon RL, White DE, Muller WJ (2007) The phosphatidyl inositol 3-kinase signaling network: implications for human breast cancer. Oncogene 26:1338-1345
    • (2007) Oncogene , vol.26 , pp. 1338-1345
    • Dillon, R.L.1    White, D.E.2    Muller, W.J.3
  • 37
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme
    • Fernandes-Alnemri T, Litwack G, Alnemri ES (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J Biol Chem 269:30761-30764
    • (1994) J Biol Chem , vol.269 , pp. 30761-30764
    • Fernandes-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 38
    • 0035879816 scopus 로고    scopus 로고
    • Expression of caspases-3, -6 and -8 and their relation to apoptosis in non-small cell lung carcinoma
    • Tormanen-Napankangas U, Soini Y, Kahlos K, Kinnula V, Paakko P (2001) Expression of caspases-3, -6 and -8 and their relation to apoptosis in non-small cell lung carcinoma. Int J Cancer 93:192-198
    • (2001) Int J Cancer , vol.93 , pp. 192-198
    • Tormanen-Napankangas, U.1    Soini, Y.2    Kahlos, K.3    Kinnula, V.4    Paakko, P.5
  • 41
    • 42449123761 scopus 로고    scopus 로고
    • Expansion and evolution of cell death programmes
    • Degterev A, Yuan J (2008) Expansion and evolution of cell death programmes. Nat Rev Mol Cell Biol 9(5):378-390
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.5 , pp. 378-390
    • Degterev, A.1    Yuan, J.2
  • 43


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.