Unraveling the structure of membrane proteins in situ by transfer function corrected cryo-electron tomography

Journal of Structural Biology

Volumn 180, Issue 3, 2012, Pages 488-496

  Eibauer, Matthias ^a,b   Hoffmann, Christian ^a,c   Plitzko, Jürgen M ^a   Baumeister, Wolfgang ^a   Nickell, Stephan ^a,d   Engelhardt, Harald ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c NOVARTIS PHARMA AG   (Switzerland)

^d CARL ZEISS SMT AG   (Germany)

Author keywords

3D electron microscopy; Contrast transfer function (CTF); Cryo electron microscopy; Modulation transfer function (MTF); Mycobacterium smegmatis; Outer membrane protein; Porin; Subtomogram averaging

Indexed keywords

OUTER MEMBRANE PROTEIN; OUTER MEMBRANE PROTEIN MSPA; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL MEMBRANE; CONTRAST TRANSFER FUNCTION; ELECTRON TOMOGRAPHY; IMAGE ANALYSIS; LIPID VESICLE; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MODULATION TRANSFER FUNCTION; MYCOBACTERIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; SIGNAL NOISE RATIO; THREE DIMENSIONAL IMAGING; X RAY CRYSTALLOGRAPHY;

ALGORITHMS; CRYOELECTRON MICROSCOPY; ELECTRON MICROSCOPE TOMOGRAPHY; ELECTRONS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MYCOBACTERIUM SMEGMATIS; PORINS; PROTEOLIPIDS; RECOMBINANT PROTEINS; SIGNAL-TO-NOISE RATIO; SOFTWARE;

MYCOBACTERIUM SMEGMATIS;

EID: 84868496402     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2012.09.008     Document Type: Article

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