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Volumn 227, Issue , 2012, Pages 283-292

Overexpression of multidrug resistance-associated protein 2 in the brain of pentylenetetrazole-kindled rats

Author keywords

Antiepileptic effect; Blood brain barrier; Multidrug resistance associated protein 2; Pharmacoresistant epilepsy; Phenytoin

Indexed keywords

BROMSULFOPHTHALEIN; MULTIDRUG RESISTANCE PROTEIN 2; PENTETRAZOLE; PHENYTOIN; PROBENECID;

EID: 84868333737     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.10.006     Document Type: Article
Times cited : (14)

References (38)
  • 2
    • 33847352626 scopus 로고    scopus 로고
    • Evaluation of therapeutic drug level monitoring of phenobarbital, phenytoin and carbamazepine in Iranian epileptic patients
    • Babaei A., Eslamai M. Evaluation of therapeutic drug level monitoring of phenobarbital, phenytoin and carbamazepine in Iranian epileptic patients. Int J Clin Pharmacol Ther 2007, 45:121-125.
    • (2007) Int J Clin Pharmacol Ther , vol.45 , pp. 121-125
    • Babaei, A.1    Eslamai, M.2
  • 3
    • 33846271368 scopus 로고    scopus 로고
    • Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein
    • Baltes S., Gastens A.M., Fedrowitz M., Potschka H., Kaever V., Löscher W. Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein. Neuropharmacology 2007, 52:333-346.
    • (2007) Neuropharmacology , vol.52 , pp. 333-346
    • Baltes, S.1    Gastens, A.M.2    Fedrowitz, M.3    Potschka, H.4    Kaever, V.5    Löscher, W.6
  • 4
    • 34247132191 scopus 로고    scopus 로고
    • Resistance to phenobarbital extends to phenytoin in a rat model of temporal lobe epilepsy
    • Bethmann K., Brandt C., Löscher W. Resistance to phenobarbital extends to phenytoin in a rat model of temporal lobe epilepsy. Epilepsia 2007, 48:816-826.
    • (2007) Epilepsia , vol.48 , pp. 816-826
    • Bethmann, K.1    Brandt, C.2    Löscher, W.3
  • 5
    • 0029046786 scopus 로고
    • Remission of epilepsy: results from the National General Practice Study of Epilepsy
    • Cockerell O., Sander J., Hart Y., Shorvon S., Johnson A. Remission of epilepsy: results from the National General Practice Study of Epilepsy. Lancet 1995, 346:140-144.
    • (1995) Lancet , vol.346 , pp. 140-144
    • Cockerell, O.1    Sander, J.2    Hart, Y.3    Shorvon, S.4    Johnson, A.5
  • 6
    • 0032769432 scopus 로고    scopus 로고
    • Enhanced susceptibility of pentylenetetrazole kindled mice to quinolone effects
    • De Sarro A., Naccari F., De Sarro G. Enhanced susceptibility of pentylenetetrazole kindled mice to quinolone effects. Int J Antimicrob Agents 1999, 12:239-244.
    • (1999) Int J Antimicrob Agents , vol.12 , pp. 239-244
    • De Sarro, A.1    Naccari, F.2    De Sarro, G.3
  • 8
    • 80052531859 scopus 로고    scopus 로고
    • Effect of penicillin G on the biliary excretion of cholephilic compounds in rats
    • Fukami M., Tanka A., Takikawa H. Effect of penicillin G on the biliary excretion of cholephilic compounds in rats. J Hepatobiliary Pancreat Sci 2011, 1-5.
    • (2011) J Hepatobiliary Pancreat Sci , pp. 1-5
    • Fukami, M.1    Tanka, A.2    Takikawa, H.3
  • 9
    • 0031897830 scopus 로고    scopus 로고
    • Antiepileptic drug-induced worsening of seizures in children
    • Guerrini R., Belmonte A., Genton P. Antiepileptic drug-induced worsening of seizures in children. Epilepsia 1998, 39:S2-S10.
    • (1998) Epilepsia , vol.39
    • Guerrini, R.1    Belmonte, A.2    Genton, P.3
  • 11
    • 33646001745 scopus 로고    scopus 로고
    • Expression of the multidrug transporter MRP2 in the blood-brain barrier after pilocarpine-induced seizures in rats
    • Hoffmann K., Gastens A.M., Volk H.A., Löscher W. Expression of the multidrug transporter MRP2 in the blood-brain barrier after pilocarpine-induced seizures in rats. Epilepsy Res 2006, 69:1-14.
    • (2006) Epilepsy Res , vol.69 , pp. 1-14
    • Hoffmann, K.1    Gastens, A.M.2    Volk, H.A.3    Löscher, W.4
  • 12
    • 77949785192 scopus 로고    scopus 로고
    • Combined effects of epileptic seizure and phenobarbital induced overexpression of P-glycoprotein in brain of chemically kindled rats
    • Jing X., Liu X., Wen T., Xie S., Yao D., Wang G., Xie L. Combined effects of epileptic seizure and phenobarbital induced overexpression of P-glycoprotein in brain of chemically kindled rats. Br J Pharmacol 2010, 159:1511-1522.
    • (2010) Br J Pharmacol , vol.159 , pp. 1511-1522
    • Jing, X.1    Liu, X.2    Wen, T.3    Xie, S.4    Yao, D.5    Wang, G.6    Xie, L.7
  • 13
    • 4344592086 scopus 로고    scopus 로고
    • Prescribing antiepileptic drugs: should patients be switched on the basis of cost?
    • Jobst B.C., Holmes G.L. Prescribing antiepileptic drugs: should patients be switched on the basis of cost?. CNS Drugs 2004, 18:617-628.
    • (2004) CNS Drugs , vol.18 , pp. 617-628
    • Jobst, B.C.1    Holmes, G.L.2
  • 15
    • 33644503533 scopus 로고    scopus 로고
    • Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis
    • Kubota H., Ishihara H., Langmann T., Schmitz G., Stieger B., Wieser H.-G., Yonekawa Y., Frei K. Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis. Epilepsy Res 2006, 68:213-228.
    • (2006) Epilepsy Res , vol.68 , pp. 213-228
    • Kubota, H.1    Ishihara, H.2    Langmann, T.3    Schmitz, G.4    Stieger, B.5    Wieser, H.-G.6    Yonekawa, Y.7    Frei, K.8
  • 16
    • 63849134803 scopus 로고    scopus 로고
    • Complex time-dependent alterations in the brain expression of different drug efflux transporter genes after status epilepticus
    • Kuteykin-Teplyakov K., Brandt C., Hoffmann K., Löscher W. Complex time-dependent alterations in the brain expression of different drug efflux transporter genes after status epilepticus. Epilepsia 2009, 50:887-897.
    • (2009) Epilepsia , vol.50 , pp. 887-897
    • Kuteykin-Teplyakov, K.1    Brandt, C.2    Hoffmann, K.3    Löscher, W.4
  • 17
    • 0345698731 scopus 로고    scopus 로고
    • Limbic epileptogenesis alters the anticonvulsant efficacy of phenytoin in Sprague-Dawley rats
    • Löscher W., Cramer S., Ebert U. Limbic epileptogenesis alters the anticonvulsant efficacy of phenytoin in Sprague-Dawley rats. Epilepsy Res 1998, 31:175-186.
    • (1998) Epilepsy Res , vol.31 , pp. 175-186
    • Löscher, W.1    Cramer, S.2    Ebert, U.3
  • 18
    • 0036128985 scopus 로고    scopus 로고
    • Role of multidrug transporters in pharmacoresistance to antiepileptic drugs
    • Löscher W., Potschka H. Role of multidrug transporters in pharmacoresistance to antiepileptic drugs. J Pharmacol Exp Ther 2002, 301:7-14.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 7-14
    • Löscher, W.1    Potschka, H.2
  • 19
    • 34848910711 scopus 로고    scopus 로고
    • ABC transporters during epilepsy and mechanisms underlying multidrug resistance in refractory epilepsy
    • Lazarowski A., Czornyj L., Lubienieki F., Girardi E., Vazquez S., D'Giano C. ABC transporters during epilepsy and mechanisms underlying multidrug resistance in refractory epilepsy. Epilepsia 2007, 48:140-149.
    • (2007) Epilepsia , vol.48 , pp. 140-149
    • Lazarowski, A.1    Czornyj, L.2    Lubienieki, F.3    Girardi, E.4    Vazquez, S.5    D'Giano, C.6
  • 20
    • 0028836283 scopus 로고
    • Effects of conventional antiepileptic drugs in a model of spontaneous recurrent seizures in rats
    • Leite J.P., Cavalheiro E.A. Effects of conventional antiepileptic drugs in a model of spontaneous recurrent seizures in rats. Epilepsy Res 1995, 20:93-104.
    • (1995) Epilepsy Res , vol.20 , pp. 93-104
    • Leite, J.P.1    Cavalheiro, E.A.2
  • 21
    • 53849141817 scopus 로고    scopus 로고
    • Involvement of P-glycoprotein, multidrug resistance protein 2 and breast cancer resistance protein in the transport of belotecan and topotecan in Caco-2 and MDCKII cells
    • Li H., Jin H.-E., Kim W., Han Y.-H., Kim D.-D., Chung S.-J., Shim C.-K. Involvement of P-glycoprotein, multidrug resistance protein 2 and breast cancer resistance protein in the transport of belotecan and topotecan in Caco-2 and MDCKII cells. Pharm Res 2008, 25:2601-2612.
    • (2008) Pharm Res , vol.25 , pp. 2601-2612
    • Li, H.1    Jin, H.-E.2    Kim, W.3    Han, Y.-H.4    Kim, D.-D.5    Chung, S.-J.6    Shim, C.-K.7
  • 22
    • 34848911714 scopus 로고    scopus 로고
    • Increased P-glycoprotein expression and decreased phenobarbital distribution in the brain of pentylenetetrazole-kindled rats
    • Liu X., Yang Z., Yang J., Yang H. Increased P-glycoprotein expression and decreased phenobarbital distribution in the brain of pentylenetetrazole-kindled rats. Neuropharmacology 2007, 53:657-663.
    • (2007) Neuropharmacology , vol.53 , pp. 657-663
    • Liu, X.1    Yang, Z.2    Yang, J.3    Yang, H.4
  • 23
    • 56349138032 scopus 로고    scopus 로고
    • Several major antiepileptic drugs are substrates for human P-glycoprotein
    • Luna-Tortós C., Fedrowitz M., Löscher W. Several major antiepileptic drugs are substrates for human P-glycoprotein. Neuropharmacology 2008, 55:1364-1375.
    • (2008) Neuropharmacology , vol.55 , pp. 1364-1375
    • Luna-Tortós, C.1    Fedrowitz, M.2    Löscher, W.3
  • 24
    • 77950949013 scopus 로고    scopus 로고
    • Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRP1, 2 and 5) that are overexpressed in pharmacoresistant epilepsy
    • Luna-Tortós C., Fedrowitz M., Löscher W. Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRP1, 2 and 5) that are overexpressed in pharmacoresistant epilepsy. Neuropharmacology 2010, 58:1019-1032.
    • (2010) Neuropharmacology , vol.58 , pp. 1019-1032
    • Luna-Tortós, C.1    Fedrowitz, M.2    Löscher, W.3
  • 25
    • 33751547871 scopus 로고    scopus 로고
    • Functional analysis of mouse and monkey multidrug resistance-associated protein 2 (Mrp2)
    • Ninomiya M., Ito K., Hiramatsu R., Horie T. Functional analysis of mouse and monkey multidrug resistance-associated protein 2 (Mrp2). Drug Metab Dispos 2006, 34:2056-2063.
    • (2006) Drug Metab Dispos , vol.34 , pp. 2056-2063
    • Ninomiya, M.1    Ito, K.2    Hiramatsu, R.3    Horie, T.4
  • 26
    • 23444451266 scopus 로고    scopus 로고
    • Simultaneous determination of lamotrigine, phenobarbitone, carbamazepine and phenytoin in human serum by high-performance liquid chromatography
    • Patil K.M., Bodhankar S.L. Simultaneous determination of lamotrigine, phenobarbitone, carbamazepine and phenytoin in human serum by high-performance liquid chromatography. J Pharm Biomed Anal 2005, 39:181-186.
    • (2005) J Pharm Biomed Anal , vol.39 , pp. 181-186
    • Patil, K.M.1    Bodhankar, S.L.2
  • 27
    • 0031883148 scopus 로고    scopus 로고
    • Antiepileptic drugs as a cause of worsening seizures
    • Perucca E., Gram L., Avanzini G., Dulac O. Antiepileptic drugs as a cause of worsening seizures. Epilepsia 1998, 39:5-17.
    • (1998) Epilepsia , vol.39 , pp. 5-17
    • Perucca, E.1    Gram, L.2    Avanzini, G.3    Dulac, O.4
  • 28
    • 0347364703 scopus 로고    scopus 로고
    • Brain access and anticonvulsant efficacy of carbamazepine, lamotrigine, and felbamate in ABCC2/MRP2-deficient TR-rats
    • Potschka H., Fedrowitz M., Löscher W. Brain access and anticonvulsant efficacy of carbamazepine, lamotrigine, and felbamate in ABCC2/MRP2-deficient TR-rats. Epilepsia 2003, 44:1479-1486.
    • (2003) Epilepsia , vol.44 , pp. 1479-1486
    • Potschka, H.1    Fedrowitz, M.2    Löscher, W.3
  • 29
    • 0037665280 scopus 로고    scopus 로고
    • Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity
    • Potschka H., Fedrowitz M., Löscher W. Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity. J Pharmacol Exp Ther 2003, 306:124-131.
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 124-131
    • Potschka, H.1    Fedrowitz, M.2    Löscher, W.3
  • 30
    • 0035828178 scopus 로고    scopus 로고
    • Multidrug resistance-associated protein is involved in the regulation of extracellular levels of phenytoin in the brain
    • Potschka H., Löscher W. Multidrug resistance-associated protein is involved in the regulation of extracellular levels of phenytoin in the brain. Neuroreport 2001, 12:2387-2389.
    • (2001) Neuroreport , vol.12 , pp. 2387-2389
    • Potschka, H.1    Löscher, W.2
  • 31
    • 0032918385 scopus 로고    scopus 로고
    • Clinical aspects and biological bases of drug-resistant epilepsies
    • Regesta G., Tanganelli P. Clinical aspects and biological bases of drug-resistant epilepsies. Epilepsy Res 1999, 34:109-122.
    • (1999) Epilepsy Res , vol.34 , pp. 109-122
    • Regesta, G.1    Tanganelli, P.2
  • 32
    • 0021176131 scopus 로고
    • Therapeutic plasma levels of phenytoin, phenobarbital, and carbamazepine
    • Schmidt D., Haenel F. Therapeutic plasma levels of phenytoin, phenobarbital, and carbamazepine. Neurology 1984, 34:1252.
    • (1984) Neurology , vol.34 , pp. 1252
    • Schmidt, D.1    Haenel, F.2
  • 33
    • 0036156280 scopus 로고    scopus 로고
    • Drug resistance in epilepsy: expression of drug resistance proteins in common causes of refractory epilepsy
    • Sisodiya S.M., Lin W.R., Harding B.N., Squier M.V., Thom M. Drug resistance in epilepsy: expression of drug resistance proteins in common causes of refractory epilepsy. Brain 2002, 125:22-31.
    • (2002) Brain , vol.125 , pp. 22-31
    • Sisodiya, S.M.1    Lin, W.R.2    Harding, B.N.3    Squier, M.V.4    Thom, M.5
  • 36
    • 27244436425 scopus 로고    scopus 로고
    • Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats
    • Van Vliet E.A., Redeker S., Aronica E., Edelbroek P.M., Gorter J.A. Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats. Epilepsia 2005, 46:1569-1580.
    • (2005) Epilepsia , vol.46 , pp. 1569-1580
    • Van Vliet, E.A.1    Redeker, S.2    Aronica, E.3    Edelbroek, P.M.4    Gorter, J.A.5
  • 38
    • 77953020053 scopus 로고    scopus 로고
    • In vitro concentration dependent transport of phenytoin and phenobarbital, but not ethosuximide, by human P-glycoprotein
    • Zhang C., Kwan P., Zuo Z., Baum L. In vitro concentration dependent transport of phenytoin and phenobarbital, but not ethosuximide, by human P-glycoprotein. Life Sci 2010, 86:899-905.
    • (2010) Life Sci , vol.86 , pp. 899-905
    • Zhang, C.1    Kwan, P.2    Zuo, Z.3    Baum, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.