메뉴 건너뛰기




Volumn 31, Issue 3, 1998, Pages 175-186

Limbic epileptogenesis alters the anticonvulsant efficacy of phenytoin in Sprague-Dawley rats

Author keywords

Antiepileptic drugs; Epilepsy; Kindling; Seizures

Indexed keywords

PHENYTOIN;

EID: 0345698731     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(98)00029-1     Document Type: Article
Times cited : (13)

References (43)
  • 1
    • 0017846870 scopus 로고
    • Effects of phenobarbital and SC-13504 on partially kindled seizures in rats
    • Albertson T., Peterson S., Stark L. Effects of phenobarbital and SC-13504 on partially kindled seizures in rats. Exp. Neurol. 61:1978;270-280.
    • (1978) Exp. Neurol. , vol.61 , pp. 270-280
    • Albertson, T.1    Peterson, S.2    Stark, L.3
  • 2
    • 0019461510 scopus 로고
    • The anticonvulsant effects of diazepam and phenobarbital in prekindled and kindled seizures in rats
    • Albertson T.E., Peterson S.L., Stark L.G. The anticonvulsant effects of diazepam and phenobarbital in prekindled and kindled seizures in rats. Neuropharmacology. 20:1981;597-603.
    • (1981) Neuropharmacology , vol.20 , pp. 597-603
    • Albertson, T.E.1    Peterson, S.L.2    Stark, L.G.3
  • 3
    • 0020695919 scopus 로고
    • Effects of carbamazepine, clonazepam, and phenytoin on seizure threshold in amygdala and cortex
    • Albright P.S. Effects of carbamazepine, clonazepam, and phenytoin on seizure threshold in amygdala and cortex. Exp. Neurol. 79:1983;11-17.
    • (1983) Exp. Neurol. , vol.79 , pp. 11-17
    • Albright, P.S.1
  • 5
    • 0001600816 scopus 로고
    • The transfer phenomenon in kindling
    • In: Wada, J.A. (Ed.), Raven Press, New York
    • Cain, D.P., 1986. The transfer phenomenon in kindling. In: Wada, J.A. (Ed.), Kindling 3. Raven Press, New York, pp. 231-248.
    • (1986) Kindling , vol.3 , pp. 231-248
    • Cain, D.P.1
  • 6
    • 0018952226 scopus 로고
    • Pharmacological modification of amygdaloid-kindled seizures
    • Callaghan D.A., Schwark W.S. Pharmacological modification of amygdaloid-kindled seizures. Neuropharmacology. 19:1980;1131-1136.
    • (1980) Neuropharmacology , vol.19 , pp. 1131-1136
    • Callaghan, D.A.1    Schwark, W.S.2
  • 7
    • 0002422840 scopus 로고
    • Phenytoin. Mechanisms of action
    • In: Levy, R.H., Mattson, R.H., Meldrum, B.S. (Eds.), Raven Press, New York
    • DeLorenzo, R.J., 1995. Phenytoin. Mechanisms of action. In: Levy, R.H., Mattson, R.H., Meldrum, B.S. (Eds.), Antiepileptic Drugs, 4th ed. Raven Press, New York, pp. 271-282.
    • (1995) Antiepileptic Drugs, 4th Ed. , pp. 271-282
    • Delorenzo, R.J.1
  • 8
    • 0030929440 scopus 로고    scopus 로고
    • Phenytoin's effect on the spread of seizure activity in the amygdala kindling model
    • Ebert U., Cramer S., Löscher W. Phenytoin's effect on the spread of seizure activity in the amygdala kindling model. Naunyn-Schmiedeberg's Arch. Pharmacol. 356:1997;341-347.
    • (1997) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.356 , pp. 341-347
    • Ebert, U.1    Cramer, S.2    Löscher, W.3
  • 9
    • 0019854869 scopus 로고
    • The effect of interstimulation interval on the assessment and stability of kindled seizure threshold
    • Freeman F.G., Jarvis M.F. The effect of interstimulation interval on the assessment and stability of kindled seizure threshold. Brain Res. Bull. 7:1981;629-633.
    • (1981) Brain Res. Bull. , vol.7 , pp. 629-633
    • Freeman, F.G.1    Jarvis, M.F.2
  • 10
    • 0021260688 scopus 로고
    • Anticonvulsant effect of primidone in the gerbil. Time course and significance of the active metabolites
    • Frey H.-H., Löscher W., Reiche R., Schultz D. Anticonvulsant effect of primidone in the gerbil. Time course and significance of the active metabolites. Pharmacology. 28:1984;329-335.
    • (1984) Pharmacology , vol.28 , pp. 329-335
    • Frey, H.-H.1    Löscher, W.2    Reiche, R.3    Schultz, D.4
  • 11
    • 0028022008 scopus 로고
    • Strategies for the development of drugs for pharmacoresistant epilepsies
    • Heinemann U., Draguhn A., Ficker E., Stabel J., Zhang C.L. Strategies for the development of drugs for pharmacoresistant epilepsies. Epilepsia. 35(Suppl. 5):1994;S10-S21.
    • (1994) Epilepsia , vol.35 , Issue.SUPPL. 5
    • Heinemann, U.1    Draguhn, A.2    Ficker, E.3    Stabel, J.4    Zhang, C.L.5
  • 12
    • 0029161428 scopus 로고
    • Kindling increases the sensitivity of rats to adverse effects of certain antiepileptic drugs
    • Hönack D., Löscher W. Kindling increases the sensitivity of rats to adverse effects of certain antiepileptic drugs. Epilepsia. 36:1995;763-771.
    • (1995) Epilepsia , vol.36 , pp. 763-771
    • Hönack, D.1    Löscher, W.2
  • 13
    • 0002297699 scopus 로고
    • Monitoring antiepileptic drug levels
    • In: Frey, H.-H., Janz, D. (Eds.), Springer, Berlin
    • Hvidberg, E.F., 1985. Monitoring antiepileptic drug levels. In: Frey, H.-H., Janz, D. (Eds.), Antiepileptic Drugs. Springer, Berlin, pp. 725-764.
    • (1985) Antiepileptic Drugs , pp. 725-764
    • Hvidberg, E.F.1
  • 15
    • 0006222956 scopus 로고
    • Hydantoins
    • In: Frey, H.-H., Janz, D. (Eds.), Springer, Berlin
    • Jones, G.L., Wimbish, G.H., 1985. Hydantoins. In: Frey, H.-H., Janz, D. (Eds.), Antiepileptic Drugs. Springer, Berlin, pp. 351-420.
    • (1985) Antiepileptic Drugs , pp. 351-420
    • Jones, G.L.1    Wimbish, G.H.2
  • 16
    • 0343223353 scopus 로고
    • Electrophysiological effects of antiepileptic drugs
    • In: Frey, H.-H., Janz, D. (Eds.), Springer, Berlin
    • Jurna, I., 1985. Electrophysiological effects of antiepileptic drugs. In: Frey, H.-H., Janz, D. (Eds.), Antiepileptic Drugs. Springer, Berlin, pp. 611-658.
    • (1985) Antiepileptic Drugs , pp. 611-658
    • Jurna, I.1
  • 17
    • 0022861558 scopus 로고
    • Seizures induced or aggravated by anticonvulsants
    • Lerman P. Seizures induced or aggravated by anticonvulsants. Epilepsia. 27:1986;706-710.
    • (1986) Epilepsia , vol.27 , pp. 706-710
    • Lerman, P.1
  • 18
    • 84910573142 scopus 로고
    • Diphenylhydantoin activated seizures
    • Levy L.L., Fenichel G.M. Diphenylhydantoin activated seizures. Neurology. 15:1965;716-722.
    • (1965) Neurology , vol.15 , pp. 716-722
    • Levy, L.L.1    Fenichel, G.M.2
  • 20
    • 0343990077 scopus 로고    scopus 로고
    • Animal models of intractable epilepsy
    • Löscher W. Animal models of intractable epilepsy. Prog. Neurobiol. 53:1997;239-258.
    • (1997) Prog. Neurobiol. , vol.53 , pp. 239-258
    • Löscher, W.1
  • 21
    • 0345019797 scopus 로고    scopus 로고
    • New visions in the pharmacology of anticonvulsion
    • Löscher W. New visions in the pharmacology of anticonvulsion. Eur. J. Pharmacol. 342:1998;1-13.
    • (1998) Eur. J. Pharmacol. , vol.342 , pp. 1-13
    • Löscher, W.1
  • 22
    • 0023897574 scopus 로고
    • Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations
    • Löscher W., Schmidt D. Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Res. 2:1988;145-181.
    • (1988) Epilepsy Res. , vol.2 , pp. 145-181
    • Löscher, W.1    Schmidt, D.2
  • 23
    • 0025246109 scopus 로고
    • High doses of memantine (1-amino-3,5-dimethyladamantane) induce seizures in kindled but not in non-kindled rats
    • Löscher W., Hönack D. High doses of memantine (1-amino-3,5-dimethyladamantane) induce seizures in kindled but not in non-kindled rats. Naunyn-Schmiedeberg's Arch. Pharmacol. 341:1990;476-481.
    • (1990) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.341 , pp. 476-481
    • Löscher, W.1    Hönack, D.2
  • 24
    • 0026065121 scopus 로고
    • Responses to NMDA receptor antagonists altered by epileptogenesis
    • Löscher W., Hönack D. Responses to NMDA receptor antagonists altered by epileptogenesis. Trends Pharmacol. Sci. 12:1991;52.
    • (1991) Trends Pharmacol. Sci. , vol.12 , pp. 52
    • Löscher, W.1    Hönack, D.2
  • 25
    • 0026075949 scopus 로고
    • Kindling as a model of drug-resistant partial epilepsy: Selection of phenytoin-resistant and nonresistant rats
    • Löscher W., Rundfeldt C. Kindling as a model of drug-resistant partial epilepsy: selection of phenytoin-resistant and nonresistant rats. J. Pharmacol. Exp. Ther. 258:1991;483-489.
    • (1991) J. Pharmacol. Exp. Ther. , vol.258 , pp. 483-489
    • Löscher, W.1    Rundfeldt, C.2
  • 26
    • 0028220347 scopus 로고
    • Strategies in antiepileptic drug development: Is rational drug design superior to random screening and structural variation?
    • Löscher W., Schmidt D. Strategies in antiepileptic drug development: is rational drug design superior to random screening and structural variation? Epilepsy Res. 17:1994;95-134.
    • (1994) Epilepsy Res. , vol.17 , pp. 95-134
    • Löscher, W.1    Schmidt, D.2
  • 27
    • 0022455261 scopus 로고
    • Is amygdala kindling in rats a model for drug-resistant partial epilepsy?
    • Löscher W., Jäckel R., Czuczwar S.J. Is amygdala kindling in rats a model for drug-resistant partial epilepsy? Exp. Neurol. 93:1986;211-226.
    • (1986) Exp. Neurol. , vol.93 , pp. 211-226
    • Löscher, W.1    Jäckel, R.2    Czuczwar, S.J.3
  • 28
    • 0025817126 scopus 로고
    • The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. III. Pentylenetetrazol seizure models
    • Löscher W., Hönack D., Fassbender C.P., Nolting B. The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. III. Pentylenetetrazol seizure models. Epilepsy Res. 8:1991;171-189.
    • (1991) Epilepsy Res. , vol.8 , pp. 171-189
    • Löscher, W.1    Hönack, D.2    Fassbender, C.P.3    Nolting, B.4
  • 29
    • 0027242081 scopus 로고
    • Pharmacological characterization of phenytoin-resistant amygdala-kindled rats, a new model of drug-resistant partial epilepsy
    • Löscher W., Rundfeldt C., Hönack D. Pharmacological characterization of phenytoin-resistant amygdala-kindled rats, a new model of drug-resistant partial epilepsy. Epilepsy Res. 15:1993;207-219.
    • (1993) Epilepsy Res. , vol.15 , pp. 207-219
    • Löscher, W.1    Rundfeldt, C.2    Hönack, D.3
  • 30
    • 0023879388 scopus 로고
    • Pursuit of the mechanisms of kindling
    • McNamara J.O. Pursuit of the mechanisms of kindling. Trends Neurosci. 11:1988;33-36.
    • (1988) Trends Neurosci. , vol.11 , pp. 33-36
    • McNamara, J.O.1
  • 31
    • 0028179659 scopus 로고
    • Cellular and molecular basis of epilepsy
    • McNamara J.O. Cellular and molecular basis of epilepsy. J. Neurosci. 14:1994;3413-3425.
    • (1994) J. Neurosci. , vol.14 , pp. 3413-3425
    • McNamara, J.O.1
  • 32
    • 0024457284 scopus 로고
    • Intravenous phenytoin is an effective anticonvulsant in the kindling model
    • McNamara J.O., Rigsbee L.C., Butler L.S., Shin C. Intravenous phenytoin is an effective anticonvulsant in the kindling model. Ann. Neurol. 26:1989;675-678.
    • (1989) Ann. Neurol. , vol.26 , pp. 675-678
    • McNamara, J.O.1    Rigsbee, L.C.2    Butler, L.S.3    Shin, C.4
  • 33
    • 0024589607 scopus 로고
    • Phenytoin-induced seizures: A paradoxical effect at toxic concentrations in epileptic patients
    • Oscorio I., Burnstine T.H., Remler B., Manon-Espaillat R., Reed R.C. Phenytoin-induced seizures: a paradoxical effect at toxic concentrations in epileptic patients. Epilepsia. 30:1989;230-234.
    • (1989) Epilepsia , vol.30 , pp. 230-234
    • Oscorio, I.1    Burnstine, T.H.2    Remler, B.3    Manon-Espaillat, R.4    Reed, R.C.5
  • 35
    • 0015309163 scopus 로고
    • Modification of seizure activity by electrical stimulation: II. Motor seizure
    • Racine R.J. Modification of seizure activity by electrical stimulation: II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 32:1972;281-294.
    • (1972) Electroencephalogr. Clin. Neurophysiol. , vol.32 , pp. 281-294
    • Racine, R.J.1
  • 36
    • 0016607403 scopus 로고
    • Effects of procaine hydrochloride, diazepam, and diphenylhydantoin on seizure development in cortical and subcortical structures in rats
    • Racine R.J., Livingston K., Joaquin A. Effects of procaine hydrochloride, diazepam, and diphenylhydantoin on seizure development in cortical and subcortical structures in rats. Electroencephalogr. Clin. Neurophysiol. 38:1975;355-365.
    • (1975) Electroencephalogr. Clin. Neurophysiol. , vol.38 , pp. 355-365
    • Racine, R.J.1    Livingston, K.2    Joaquin, A.3
  • 37
    • 0025050694 scopus 로고
    • Antiepileptic drugs: Pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds
    • Rogawski M.A., Porter R.J. Antiepileptic drugs: pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds. Pharmacol. Rev. 42:1990;223-286.
    • (1990) Pharmacol. Rev. , vol.42 , pp. 223-286
    • Rogawski, M.A.1    Porter, R.J.2
  • 38
    • 0025168396 scopus 로고
    • Phenytoin potently increases the threshold for focal seizures in amygdala-kindled rats
    • Rundfeldt C., Hönack D., Löscher W. Phenytoin potently increases the threshold for focal seizures in amygdala-kindled rats. Neuropharmacology. 29:1990;845-851.
    • (1990) Neuropharmacology , vol.29 , pp. 845-851
    • Rundfeldt, C.1    Hönack, D.2    Löscher, W.3
  • 41
    • 0022625903 scopus 로고
    • The influence of seizure type on the efficacy of plasma concentrations of phenytoin, phenobarbital, and carbamazepine
    • Schmidt D., Einicke I., Haenel F. The influence of seizure type on the efficacy of plasma concentrations of phenytoin, phenobarbital, and carbamazepine. Arch. Neurol. 43:1986;263-265.
    • (1986) Arch. Neurol. , vol.43 , pp. 263-265
    • Schmidt, D.1    Einicke, I.2    Haenel, F.3
  • 42
    • 0018405907 scopus 로고
    • Behavioural analysis of amygdaloid kindling in Beagle dogs and the effects of clonazepam, diazepam, phenobarbital, diphenylhydantoin, and flunarizine on seizure manifestations
    • Wauquier A., Ashton D., Melis W. Behavioural analysis of amygdaloid kindling in Beagle dogs and the effects of clonazepam, diazepam, phenobarbital, diphenylhydantoin, and flunarizine on seizure manifestations. Exp. Neurol. 64:1979;579-586.
    • (1979) Exp. Neurol. , vol.64 , pp. 579-586
    • Wauquier, A.1    Ashton, D.2    Melis, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.