-
1
-
-
70350443414
-
Enhanced peroxisome proliferator-activated receptor-gamma expression in monocyte/macrophages from coronary artery disease patients and possible gender differences
-
Amoruso A, Bardelli C, Fresu LG, Palma A, Vidali M, Ferrero V, Ribichini F, Vassanelli C, Brunelleschi S (2009) Enhanced peroxisome proliferator- activated receptor-gamma expression in monocyte/macrophages from coronary artery disease patients and possible gender differences. J Pharmacol Exp Ther 331:531-538
-
(2009)
J Pharmacol Exp Ther
, vol.331
, pp. 531-538
-
-
Amoruso, A.1
Bardelli, C.2
Fresu, L.G.3
Palma, A.4
Vidali, M.5
Ferrero, V.6
Ribichini, F.7
Vassanelli, C.8
Brunelleschi, S.9
-
2
-
-
77958093616
-
Rosiglitazone and pioglitazone increase fracture risk in women and men with type 2 diabetes
-
Aubert RE, Herrera V, Chen W, Haffner SM, Pendergrass M (2010) Rosiglitazone and pioglitazone increase fracture risk in women and men with type 2 diabetes. Diabetes Obes Metab 12:716-721
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 716-721
-
-
Aubert, R.E.1
Herrera, V.2
Chen, W.3
Haffner, S.M.4
Pendergrass, M.5
-
3
-
-
0030747895
-
Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: No alteration in adipose tissue of obese and NIDDM patients
-
Auboeuf D, Rieusset J, Fajas L, Vallier P, Frering V, Riou JP, Staels B, Auwerx J, Laville M, Vidal H (1997) Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients. Diabetes 46:1319-1327
-
(1997)
Diabetes
, vol.46
, pp. 1319-1327
-
-
Auboeuf, D.1
Rieusset, J.2
Fajas, L.3
Vallier, P.4
Frering, V.5
Riou, J.P.6
Staels, B.7
Auwerx, J.8
Laville, M.9
Vidal, H.10
-
4
-
-
3242724126
-
Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)gamma-2 with longevity
-
Barbieri M, Bonafe M, Rizzo MR, Ragno E, Olivieri F, Marchegiani F, Franceschi C, Paolisso G (2004) Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)gamma-2 with longevity. Exp Gerontol 39:1095-1100
-
(2004)
Exp Gerontol
, vol.39
, pp. 1095-1100
-
-
Barbieri, M.1
Bonafe, M.2
Rizzo, M.R.3
Ragno, E.4
Olivieri, F.5
Marchegiani, F.6
Franceschi, C.7
Paolisso, G.8
-
5
-
-
0031667127
-
Association of the pro12ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two caucasian populations
-
Beamer BA, Yen CJ, Andersen RE, Muller D, Elahi D, Cheskin LJ, Andres R, Roth J, Shuldiner AR (1998) Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations. Diabetes 47:1806-1808
-
(1998)
Diabetes
, vol.47
, pp. 1806-1808
-
-
Beamer, B.A.1
Yen, C.J.2
Andersen, R.E.3
Muller, D.4
Elahi, D.5
Cheskin, L.J.6
Andres, R.7
Roth, J.8
Shuldiner, A.R.9
-
6
-
-
10744228147
-
Species and gender differences in the formation of an active metabolite of a substituted 2,4-thiazolidinedione insulin sensitizer
-
Beconi M, Mao A, Creighton M, Hop CE, Chiu SH, Eydelloth R, Franklin R, Tang F, Yu N, Vincent S (2003) Species and gender differences in the formation of an active metabolite of a substituted 2,4-thiazolidinedione insulin sensitizer. Xenobiotica 33:767-787
-
(2003)
Xenobiotica
, vol.33
, pp. 767-787
-
-
Beconi, M.1
Mao, A.2
Creighton, M.3
Hop, C.E.4
Chiu, S.H.5
Eydelloth, R.6
Franklin, R.7
Tang, F.8
Yu, N.9
Vincent, S.10
-
7
-
-
70349783791
-
Gender-specific effect of pro12ala polymorphism in peroxisome proliferator-activated receptor gamma-2 gene on obesity risk and leptin levels in a Tunisian population
-
Ben Ali S, Ben Yahia F, Sediri Y, Kallel A, Ftouhi B, Feki M, Elasmi M, Haj-Taieb S, Souheil O, Sanhagi H et al (2009) Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma-2 gene on obesity risk and leptin levels in a Tunisian population. Clin Biochem 42:1642-1647
-
(2009)
Clin Biochem
, vol.42
, pp. 1642-1647
-
-
Ben Ali, S.1
Ben Yahia, F.2
Sediri, Y.3
Kallel, A.4
Ftouhi, B.5
Feki, M.6
Elasmi, M.7
Haj-Taieb, S.8
Souheil, O.9
Sanhagi, H.10
-
8
-
-
0036183630
-
The mechanisms of action of PPARs
-
Berger J, Moller DE (2002) The mechanisms of action of PPARs. Annu Rev Med 53:409-435
-
(2002)
Annu Rev Med
, vol.53
, pp. 409-435
-
-
Berger, J.1
Moller, D.E.2
-
9
-
-
77957779218
-
Thiazolidinediones and fractures: Evidence from translating research into action for diabetes
-
Bilik D, McEwen LN, Brown MB, Pomeroy NE, Kim C, Asao K, Crosson JC, Duru OK, Ferrara A, Hsiao VC et al (2010) Thiazolidinediones and fractures: evidence from translating research into action for diabetes. J Clin Endocrinol Metab 95:4560-4565
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 4560-4565
-
-
Bilik, D.1
McEwen, L.N.2
Brown, M.B.3
Pomeroy, N.E.4
Kim, C.5
Asao, K.6
Crosson, J.C.7
Duru, O.K.8
Ferrara, A.9
Hsiao, V.C.10
-
10
-
-
11844296800
-
Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: A meta-analysis of randomized controlled trials
-
Birjmohun RS, Hutten BA, Kastelein JJ, Stroes ES (2005) Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials. J Am Coll Cardiol 45:185-197
-
(2005)
J Am Coll Cardiol
, vol.45
, pp. 185-197
-
-
Birjmohun, R.S.1
Hutten, B.A.2
Kastelein, J.J.3
Stroes, E.S.4
-
11
-
-
0035744752
-
Gender differences in fat metabolism
-
Blaak E (2001) Gender differences in fat metabolism. Curr Opin Clin Nutr Metab Care 4:499-502
-
(2001)
Curr Opin Clin Nutr Metab Care
, vol.4
, pp. 499-502
-
-
Blaak, E.1
-
12
-
-
0029981772
-
Differential activation of adipogenesis by multiple PPAR isoforms
-
Brun RP, Tontonoz P, Forman BM, Ellis R, Chen J, Evans RM, Spiegelman BM (1996) Differential activation of adipogenesis by multiple PPAR isoforms. Genes Dev 10:974-984
-
(1996)
Genes Dev
, vol.10
, pp. 974-984
-
-
Brun, R.P.1
Tontonoz, P.2
Forman, B.M.3
Ellis, R.4
Chen, J.5
Evans, R.M.6
Spiegelman, B.M.7
-
13
-
-
0041852780
-
17beta-estradiol upregulates the expression of peroxisome proliferator-activated receptor alpha and lipid oxidative genes in skeletal muscle
-
Campbell SE, Mehan KA, Tunstall RJ, Febbraio MA, Cameron-Smith D (2003) 17beta-estradiol upregulates the expression of peroxisome proliferator-activated receptor alpha and lipid oxidative genes in skeletal muscle. J Mol Endocrinol 31:37-45
-
(2003)
J Mol Endocrinol
, vol.31
, pp. 37-45
-
-
Campbell, S.E.1
Mehan, K.A.2
Tunstall, R.J.3
Febbraio, M.A.4
Cameron-Smith, D.5
-
14
-
-
0016824466
-
Editorial: Results of the coronary drug project - An interpretation
-
Carlson LA, Rossner S (1975) Editorial: results of the coronary drug project - an interpretation. Atherosclerosis 22:317-323
-
(1975)
Atherosclerosis
, vol.22
, pp. 317-323
-
-
Carlson, L.A.1
Rossner, S.2
-
15
-
-
0034979124
-
Substrate utilization during endurance exercise in men and women after endurance training
-
Carter SL, Rennie C, Tarnopolsky MA (2001) Substrate utilization during endurance exercise in men and women after endurance training. Am J Physiol 280:E898-E907
-
(2001)
Am J Physiol
, vol.280
-
-
Carter, S.L.1
Rennie, C.2
Tarnopolsky, M.A.3
-
16
-
-
0029121358
-
Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor
-
Cavailles V, Dauvois S, L'Horset F, Lopez G, Hoare S, Kushner PJ, Parker MG (1995) Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor. EMBO J 14:3741-3751
-
(1995)
EMBO J
, vol.14
, pp. 3741-3751
-
-
Cavailles, V.1
Dauvois, S.2
L'Horset, F.3
Lopez, G.4
Hoare, S.5
Kushner, P.J.6
Parker, M.G.7
-
17
-
-
0034630720
-
Fenofibrate and rosiglitazone lower serum triglycerides with opposing effects on body weight
-
Chaput E, Saladin R, Silvestre M, Edgar AD (2000) Fenofibrate and rosiglitazone lower serum triglycerides with opposing effects on body weight. Biochem Biophys Res Commun 271:445-450
-
(2000)
Biochem Biophys Res Commun
, vol.271
, pp. 445-450
-
-
Chaput, E.1
Saladin, R.2
Silvestre, M.3
Edgar, A.D.4
-
18
-
-
33846616376
-
A novel peroxisome proliferator-activated receptor responsive element-luciferase reporter mouse reveals gender specificity of peroxisome proliferator-activated receptor activity in liver
-
Ciana P, Biserni A, Tatangelo L, Tiveron C, Sciarroni AF, Ottobrini L, Maggi A (2007) A novel peroxisome proliferator-activated receptor responsive element-luciferase reporter mouse reveals gender specificity of peroxisome proliferator-activated receptor activity in liver. Mol Endocrinol 21:388-400
-
(2007)
Mol Endocrinol
, vol.21
, pp. 388-400
-
-
Ciana, P.1
Biserni, A.2
Tatangelo, L.3
Tiveron, C.4
Sciarroni, A.F.5
Ottobrini, L.6
Maggi, A.7
-
19
-
-
26244441014
-
The farnesoid X receptor: A molecular link between bile acid and lipid and glucose metabolism
-
Claudel T, Staels B, Kuipers F (2005) The Farnesoid X receptor: a molecular link between bile acid and lipid and glucose metabolism. Arterioscler Thromb Vasc Biol 25:2020-2030
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 2020-2030
-
-
Claudel, T.1
Staels, B.2
Kuipers, F.3
-
20
-
-
0032491614
-
Peroxisome proliferator-activated receptor alpha-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis
-
Costet P, Legendre C, More J, Edgar A, Galtier P, Pineau T (1998) Peroxisome proliferator-activated receptor alpha-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis. J Biol Chem 273:29577-29585
-
(1998)
J Biol Chem
, vol.273
, pp. 29577-29585
-
-
Costet, P.1
Legendre, C.2
More, J.3
Edgar, A.4
Galtier, P.5
Pineau, T.6
-
21
-
-
73349143317
-
PPAR-alpha contributes to the anti-inflammatory activity of 17beta-estradiol
-
Crisafulli C, Bruscoli S, Esposito E, Mazzon E, Di Paola R, Genovese T, Bramanti P, Migliorati G, Cuzzocrea S (2009) PPAR-alpha contributes to the anti-inflammatory activity of 17beta-estradiol. J Pharmacol Exp Ther 331:796-807
-
(2009)
J Pharmacol Exp Ther
, vol.331
, pp. 796-807
-
-
Crisafulli, C.1
Bruscoli, S.2
Esposito, E.3
Mazzon, E.4
Di Paola, R.5
Genovese, T.6
Bramanti, P.7
Migliorati, G.8
Cuzzocrea, S.9
-
22
-
-
77951228956
-
The immunomodulatory effects of estrogens: Clinical relevance in immune-mediated rheumatic diseases
-
Cutolo M, Brizzolara R, Atzeni F, Capellino S, Straub RH, Puttini PC (2010) The immunomodulatory effects of estrogens: clinical relevance in immune-mediated rheumatic diseases. Ann N Y Acad Sci 1193:36-42
-
(2010)
Ann N y Acad Sci
, vol.1193
, pp. 36-42
-
-
Cutolo, M.1
Brizzolara, R.2
Atzeni, F.3
Capellino, S.4
Straub, R.H.5
Puttini, P.C.6
-
23
-
-
77956715369
-
Impact of triglycerides on lipid and lipoprotein biology in women
-
Dayspring TD, Pokrywka G (2010) Impact of triglycerides on lipid and lipoprotein biology in women. Gend Med 7:189-205
-
(2010)
Gend Med
, vol.7
, pp. 189-205
-
-
Dayspring, T.D.1
Pokrywka, G.2
-
24
-
-
0032828454
-
The effect of menopause on blood lipid and lipoprotein levels
-
The Icarus Study Group
-
de Aloysio D, Gambacciani M, Meschia M, Pansini F, Bacchi Modena A, Bolis PF, Massobrio M, Maiocchi G, Peruzzi E (1999) The effect of menopause on blood lipid and lipoprotein levels. The Icarus Study Group. Atherosclerosis 147:147-153
-
(1999)
Atherosclerosis
, vol.147
, pp. 147-153
-
-
De Aloysio, D.1
Gambacciani, M.2
Meschia, M.3
Pansini, F.4
Bacchi Modena, A.5
Bolis, P.F.6
Massobrio, M.7
Maiocchi, G.8
Peruzzi, E.9
-
25
-
-
33750475959
-
Cross-talk between nuclear receptors and nuclear factor kappaB
-
De Bosscher K, Vanden Berghe W, Haegeman G (2006) Cross-talk between nuclear receptors and nuclear factor kappaB. Oncogene 25:6868-6886
-
(2006)
Oncogene
, vol.25
, pp. 6868-6886
-
-
De Bosscher, K.1
Vanden Berghe, W.2
Haegeman, G.3
-
26
-
-
33846221498
-
The pro12ala polymorphism in PPARgamma2 gene affects lipid parameters in greek primary school children: A case of gene-to-gender interaction
-
Dedoussis GV, Theodoraki EV, Manios Y, Yiannakouris N, Panagiotakos D, Papoutsakis C, Skenderi K, Zampelas A (2007) The Pro12Ala polymorphism in PPARgamma2 gene affects lipid parameters in Greek primary school children: a case of gene-to-gender interaction. Am J Med Sci 333:10-15
-
(2007)
Am J Med Sci
, vol.333
, pp. 10-15
-
-
Dedoussis, G.V.1
Theodoraki, E.V.2
Manios, Y.3
Yiannakouris, N.4
Panagiotakos, D.5
Papoutsakis, C.6
Skenderi, K.7
Zampelas, A.8
-
27
-
-
70349501470
-
Peroxisome proliferator-activated receptor-gamma (PPARgamma) pro12ala polymorphism and risk for pediatric obesity
-
Dedoussis GV, Vidra N, Butler J, Papoutsakis C, Yannakoulia M, Hirschhorn JN, Lyon HN (2009) Peroxisome proliferator-activated receptor-gamma (PPARgamma) Pro12Ala polymorphism and risk for pediatric obesity. Clin Chem Lab Med 47:1047-1050
-
(2009)
Clin Chem Lab Med
, vol.47
, pp. 1047-1050
-
-
Dedoussis, G.V.1
Vidra, N.2
Butler, J.3
Papoutsakis, C.4
Yannakoulia, M.5
Hirschhorn, J.N.6
Lyon, H.N.7
-
28
-
-
0031595923
-
A pro12ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
-
Deeb SS, Fajas L, Nemoto M, Pihlajamaki J, Mykkanen L, Kuusisto J, Laakso M, Fujimoto W, Auwerx J (1998) A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet 20:284-287
-
(1998)
Nat Genet
, vol.20
, pp. 284-287
-
-
Deeb, S.S.1
Fajas, L.2
Nemoto, M.3
Pihlajamaki, J.4
Mykkanen, L.5
Kuusisto, J.6
Laakso, M.7
Fujimoto, W.8
Auwerx, J.9
-
29
-
-
58549100843
-
Pioglitazone versus rosiglitazone: Effects on lipids, lipoproteins, and apolipoproteins in head-to-head randomized clinical studies
-
Deeg MA, Tan MH (2008) Pioglitazone versus rosiglitazone: effects on lipids, lipoproteins, and apolipoproteins in head-to-head randomized clinical studies. PPAR Res 2008:520465
-
(2008)
PPAR Res
, vol.2008
, pp. 520465
-
-
Deeg, M.A.1
Tan, M.H.2
-
30
-
-
0033527569
-
Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1
-
Delerive P, De Bosscher K, Besnard S, Vanden Berghe W, Peters JM, Gonzalez FJ, Fruchart JC, Tedgui A, Haegeman G, Staels B (1999) Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1. J Biol Chem 274:32048-32054
-
(1999)
J Biol Chem
, vol.274
, pp. 32048-32054
-
-
Delerive, P.1
De Bosscher, K.2
Besnard, S.3
Vanden Berghe, W.4
Peters, J.M.5
Gonzalez, F.J.6
Fruchart, J.C.7
Tedgui, A.8
Haegeman, G.9
Staels, B.10
-
31
-
-
0033305213
-
Peroxisome proliferator-activated receptors: Nuclear control of metabolism
-
Desvergne B, Wahli W (1999) Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 20:649-688
-
(1999)
Endocr Rev
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
32
-
-
0029661982
-
The PPARalphaleukotriene B4 pathway to inflammation control
-
Devchand PR, Keller H, Peters JM, Vazquez M, Gonzalez FJ, Wahli W (1996) The PPARalphaleukotriene B4 pathway to inflammation control. Nature 384:39-43
-
(1996)
Nature
, vol.384
, pp. 39-43
-
-
Devchand, P.R.1
Keller, H.2
Peters, J.M.3
Vazquez, M.4
Gonzalez, F.J.5
Wahli, W.6
-
33
-
-
0032530765
-
A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator-activated receptor alpha-deficient mice
-
Djouadi F, Weinheimer CJ, Saffitz JE, Pitchford C, Bastin J, Gonzalez FJ, Kelly DP (1998) A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator-activated receptor alpha- deficient mice. J Clin Invest 102:1083-1091
-
(1998)
J Clin Invest
, vol.102
, pp. 1083-1091
-
-
Djouadi, F.1
Weinheimer, C.J.2
Saffitz, J.E.3
Pitchford, C.4
Bastin, J.5
Gonzalez, F.J.6
Kelly, D.P.7
-
34
-
-
26244453309
-
Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive study (PROspective pioglitAzone clinical trial in macroVascular events): A randomised controlled trial
-
Dormandy JA, Charbonnel B, Eckland DJ, Erdmann E, Massi-Benedetti M, Moules IK, Skene AM, Tan MH, Lefebvre PJ, Murray GD et al (2005) Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet 366:1279-1289
-
(2005)
Lancet
, vol.366
, pp. 1279-1289
-
-
Dormandy, J.A.1
Charbonnel, B.2
Eckland, D.J.3
Erdmann, E.4
Massi-Benedetti, M.5
Moules, I.K.6
Skene, A.M.7
Tan, M.H.8
Lefebvre, P.J.9
Murray, G.D.10
-
35
-
-
51349089115
-
Sex differences in autoimmune disease from a pathological perspective
-
Fairweather D, Frisancho-Kiss S, Rose NR (2008) Sex differences in autoimmune disease from a pathological perspective. Am J Pathol 173:600-609
-
(2008)
Am J Pathol
, vol.173
, pp. 600-609
-
-
Fairweather, D.1
Frisancho-Kiss, S.2
Rose, N.R.3
-
36
-
-
0842263981
-
The biology of peroxisome proliferator-activated receptors: Relationship with lipid metabolism and insulin sensitivity
-
Ferre P (2004) The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity. Diabetes 53(Suppl 1):S43-S50
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 1
-
-
Ferre, P.1
-
37
-
-
0028972025
-
15-deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
-
Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM (1995) 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 83:803-812
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
Brun, R.P.4
Spiegelman, B.M.5
Evans, R.M.6
-
38
-
-
0030952937
-
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
-
Forman BM, Chen J, Evans RM (1997) Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci USA 94:4312-4317
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4312-4317
-
-
Forman, B.M.1
Chen, J.2
Evans, R.M.3
-
39
-
-
46249083607
-
Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma
-
Foryst-Ludwig A, Clemenz M, Hohmann S, Hartge M, Sprang C, Frost N, Krikov M, Bhanot S, Barros R, Morani A et al (2008) Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma. PLoS Genet 4:e1000108
-
(2008)
PLoS Genet
, vol.4
-
-
Foryst-Ludwig, A.1
Clemenz, M.2
Hohmann, S.3
Hartge, M.4
Sprang, C.5
Frost, N.6
Krikov, M.7
Bhanot, S.8
Barros, R.9
Morani, A.10
-
40
-
-
0342506477
-
Prevention of the angiographic progression of coronary and vein-graft atherosclerosis by gemfibrozil after coronary bypass surgery in men with low levels of HDL cholesterol
-
Lopid Coronary Angiography Trial (LOCAT) Study Group
-
Frick MH, Syvanne M, Nieminen MS, Kauma H, Majahalme S, Virtanen V, Kesaniemi YA, Pasternack A, Taskinen MR (1997) Prevention of the angiographic progression of coronary and vein-graft atherosclerosis by gemfibrozil after coronary bypass surgery in men with low levels of HDL cholesterol. Lopid Coronary Angiography Trial (LOCAT) Study Group. Circulation 96:2137-2143
-
(1997)
Circulation
, vol.96
, pp. 2137-2143
-
-
Frick, M.H.1
Syvanne, M.2
Nieminen, M.S.3
Kauma, H.4
Majahalme, S.5
Virtanen, V.6
Kesaniemi, Y.A.7
Pasternack, A.8
Taskinen, M.R.9
-
41
-
-
0035924635
-
Peroxisome proliferator-activated receptor-alpha activation and high-density lipoprotein metabolism
-
Fruchart JC (2001) Peroxisome proliferator-activated receptor-alpha activation and high-density lipoprotein metabolism. Am J Cardiol 88:24N-29N
-
(2001)
Am J Cardiol
, vol.88
-
-
Fruchart, J.C.1
-
42
-
-
1542714421
-
Sex differences in the pharmacokinetics of pioglitazone in rats
-
Fujita Y, Yamada Y, Kusama M, Yamauchi T, Kamon J, Kadowaki T, Iga T (2003) Sex differences in the pharmacokinetics of pioglitazone in rats. Comp Biochem Physiol C Toxicol Pharmacol 136:85-94
-
(2003)
Comp Biochem Physiol C Toxicol Pharmacol
, vol.136
, pp. 85-94
-
-
Fujita, Y.1
Yamada, Y.2
Kusama, M.3
Yamauchi, T.4
Kamon, J.5
Kadowaki, T.6
Iga, T.7
-
44
-
-
33748748206
-
Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: A randomised controlled trial
-
Gerstein HC, Yusuf S, Bosch J, Pogue J, Sheridan P, Dinccag N, Hanefeld M, Hoogwerf B, Laakso M, Mohan V et al (2006) Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial. Lancet 368:1096-1105
-
(2006)
Lancet
, vol.368
, pp. 1096-1105
-
-
Gerstein, H.C.1
Yusuf, S.2
Bosch, J.3
Pogue, J.4
Sheridan, P.5
Dinccag, N.6
Hanefeld, M.7
Hoogwerf, B.8
Laakso, M.9
Mohan, V.10
-
45
-
-
77951704587
-
Effects of combination lipid therapy in type 2 diabetes mellitus
-
Ginsberg HN, Elam MB, Lovato LC, Crouse JR 3rd, Leiter LA, Linz P, Friedewald WT, Buse JB, Gerstein HC, Probstfield J et al (2010) Effects of combination lipid therapy in type 2 diabetes mellitus. N Engl J Med 362:1563-1574
-
(2010)
N Engl J Med
, vol.362
, pp. 1563-1574
-
-
Ginsberg, H.N.1
Elam, M.B.2
Lovato, L.C.3
Crouse III, J.R.4
Leiter, L.A.5
Linz, P.6
Friedewald, W.T.7
Buse, J.B.8
Gerstein, H.C.9
Probstfield, J.10
-
46
-
-
33644636344
-
Going nuclear in metabolic and cardiovascular disease
-
Glass CK (2006) Going nuclear in metabolic and cardiovascular disease. J Clin Invest 116:556-560
-
(2006)
J Clin Invest
, vol.116
, pp. 556-560
-
-
Glass, C.K.1
-
47
-
-
13844262924
-
Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes
-
Guan HP, Ishizuka T, Chui PC, Lehrke M, Lazar MA (2005) Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes. Genes Dev 19:453-461
-
(2005)
Genes Dev
, vol.19
, pp. 453-461
-
-
Guan, H.P.1
Ishizuka, T.2
Chui, P.C.3
Lehrke, M.4
Lazar, M.A.5
-
48
-
-
0034595980
-
Peroxisome proliferator-activated receptor alpha activators improve insulin sensitivity and reduce adiposity
-
Guerre-Millo M, Gervois P, Raspe E, Madsen L, Poulain P, Derudas B, Herbert JM, Winegar DA, Willson TM, Fruchart JC et al (2000) Peroxisome proliferator-activated receptor alpha activators improve insulin sensitivity and reduce adiposity. J Biol Chem 275:16638-16642
-
(2000)
J Biol Chem
, vol.275
, pp. 16638-16642
-
-
Guerre-Millo, M.1
Gervois, P.2
Raspe, E.3
Madsen, L.4
Poulain, P.5
Derudas, B.6
Herbert, J.M.7
Winegar, D.A.8
Willson, T.M.9
Fruchart, J.C.10
-
49
-
-
76149114236
-
Thiazolidinedione use and the longitudinal risk of fractures in patients with type 2 diabetes mellitus
-
Habib ZA, Havstad SL, Wells K, Divine G, Pladevall M, Williams LK (2010) Thiazolidinedione use and the longitudinal risk of fractures in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 95:592-600
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 592-600
-
-
Habib, Z.A.1
Havstad, S.L.2
Wells, K.3
Divine, G.4
Pladevall, M.5
Williams, L.K.6
-
50
-
-
0036736212
-
Molecular pathways to obesity
-
Hofbauer KG (2002) Molecular pathways to obesity. Int J Obes Relat Metab Disord 26(Suppl 2): S18-S27
-
(2002)
Int J Obes Relat Metab Disord
, vol.26
, Issue.SUPPL. 2
-
-
Hofbauer, K.G.1
-
51
-
-
67149146438
-
Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): A multicentre, randomised, open-label trial
-
Home PD, Pocock SJ, Beck-Nielsen H, Curtis PS, Gomis R, Hanefeld M, Jones NP, Komajda M, McMurray JJ (2009) Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial. Lancet 373:2125-2135
-
(2009)
Lancet
, vol.373
, pp. 2125-2135
-
-
Home, P.D.1
Pocock, S.J.2
Beck-Nielsen, H.3
Curtis, P.S.4
Gomis, R.5
Hanefeld, M.6
Jones, N.P.7
Komajda, M.8
McMurray, J.J.9
-
52
-
-
34548150238
-
Metabolic modulators following trauma sepsis: Sex hormones
-
Hsieh YC, Frink M, Choudhry MA, Bland KI, Chaudry IH (2007) Metabolic modulators following trauma sepsis: sex hormones. Crit Care Med 35:S621-S629
-
(2007)
Crit Care Med
, vol.35
-
-
Hsieh, Y.C.1
Frink, M.2
Choudhry, M.A.3
Bland, K.I.4
Chaudry, I.H.5
-
53
-
-
0037225347
-
Sex difference in hepatic peroxisome proliferator-activated receptor alpha expression: Influence of pituitary and gonadal hormones
-
Jalouli M, Carlsson L, Ameen C, Linden D, Ljungberg A, Michalik L, Eden S, Wahli W, Oscarsson J (2003) Sex difference in hepatic peroxisome proliferator-activated receptor alpha expression: influence of pituitary and gonadal hormones. Endocrinology 144:101-109
-
(2003)
Endocrinology
, vol.144
, pp. 101-109
-
-
Jalouli, M.1
Carlsson, L.2
Ameen, C.3
Linden, D.4
Ljungberg, A.5
Michalik, L.6
Eden, S.7
Wahli, W.8
Oscarsson, J.9
-
54
-
-
0034664769
-
Combinatorial roles of the nuclear receptor corepressor in transcription and development
-
Jepsen K, Hermanson O, Onami TM, Gleiberman AS, Lunyak V, McEvilly RJ, Kurokawa R, Kumar V, Liu F, Seto E et al (2000) Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell 102:753-763
-
(2000)
Cell
, vol.102
, pp. 753-763
-
-
Jepsen, K.1
Hermanson, O.2
Onami, T.M.3
Gleiberman, A.S.4
Lunyak, V.5
McEvilly, R.J.6
Kurokawa, R.7
Kumar, V.8
Liu, F.9
Seto, E.10
-
55
-
-
74249097743
-
Rosiglitazone decreases C-reactive protein to a greater extent relative to glyburide and metformin over 4 years despite greater weight gain: Observations from a diabetes outcome progression trial (ADOPT)
-
Kahn SE, Haffner SM, Viberti G, Herman WH, Lachin JM, Kravitz BG, Yu D, Paul G, Holman RR, Zinman B (2010) Rosiglitazone decreases C-reactive protein to a greater extent relative to glyburide and metformin over 4 years despite greater weight gain: observations from a Diabetes Outcome Progression Trial (ADOPT). Diabetes Care 33:177-183
-
(2010)
Diabetes Care
, vol.33
, pp. 177-183
-
-
Kahn, S.E.1
Haffner, S.M.2
Viberti, G.3
Herman, W.H.4
Lachin, J.M.5
Kravitz, B.G.6
Yu, D.7
Paul, G.8
Holman, R.R.9
Zinman, B.10
-
56
-
-
0142091356
-
PPARgamma coactivator 1beta/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity
-
Kamei Y, Ohizumi H, Fujitani Y, Nemoto T, Tanaka T, Takahashi N, Kawada T, Miyoshi M, Ezaki O, Kakizuka A (2003) PPARgamma coactivator 1beta/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity. Proc Natl Acad Sci USA 100:12378-12383
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12378-12383
-
-
Kamei, Y.1
Ohizumi, H.2
Fujitani, Y.3
Nemoto, T.4
Tanaka, T.5
Takahashi, N.6
Kawada, T.7
Miyoshi, M.8
Ezaki, O.9
Kakizuka, A.10
-
57
-
-
28044452217
-
Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): Randomised controlled trial
-
Keech A, Simes RJ, Barter P, Best J, Scott R, Taskinen MR, Forder P, Pillai A, Davis T, Glasziou P et al (2005) Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet 366:1849-1861
-
(2005)
Lancet
, vol.366
, pp. 1849-1861
-
-
Keech, A.1
Simes, R.J.2
Barter, P.3
Best, J.4
Scott, R.5
Taskinen, M.R.6
Forder, P.7
Pillai, A.8
Davis, T.9
Glasziou, P.10
-
58
-
-
0027447461
-
Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers
-
Keller H, Dreyer C, Medin J, Mahfoudi A, Ozato K, Wahli W (1993) Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers. Proc Natl Acad Sci USA 90:2160-2164
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 2160-2164
-
-
Keller, H.1
Dreyer, C.2
Medin, J.3
Mahfoudi, A.4
Ozato, K.5
Wahli, W.6
-
59
-
-
0029067225
-
Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements
-
Keller H, Givel F, Perroud M, Wahli W (1995) Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements. Mol Endocrinol 9:794-804
-
(1995)
Mol Endocrinol
, vol.9
, pp. 794-804
-
-
Keller, H.1
Givel, F.2
Perroud, M.3
Wahli, W.4
-
60
-
-
4544378971
-
Lipid-binding proteins and lipoprotein lipase activity in human skeletal muscle: Influence of physical activity and gender
-
Kiens B, Roepstorff C, Glatz JF, Bonen A, Schjerling P, Knudsen J, Nielsen JN (2004) Lipid-binding proteins and lipoprotein lipase activity in human skeletal muscle: influence of physical activity and gender. J Appl Physiol 97:1209-1218
-
(2004)
J Appl Physiol
, vol.97
, pp. 1209-1218
-
-
Kiens, B.1
Roepstorff, C.2
Glatz, J.F.3
Bonen, A.4
Schjerling, P.5
Knudsen, J.6
Nielsen, J.N.7
-
61
-
-
0019943007
-
Relation of body fat distribution to metabolic complications of obesity
-
Kissebah AH, Vydelingum N, Murray R, Evans DJ, Hartz AJ, Kalkhoff RK, Adams PW (1982) Relation of body fat distribution to metabolic complications of obesity. J Clin Endocrinol Metab 54:254-260
-
(1982)
J Clin Endocrinol Metab
, vol.54
, pp. 254-260
-
-
Kissebah, A.H.1
Vydelingum, N.2
Murray, R.3
Evans, D.J.4
Hartz, A.J.5
Kalkhoff, R.K.6
Adams, P.W.7
-
62
-
-
77952302572
-
Elevated production of docosahexaenoic acid in females: Potential molecular mechanisms
-
Kitson AP, Stroud CK, Stark KD (2010) Elevated production of docosahexaenoic acid in females: potential molecular mechanisms. Lipids 45:209-224
-
(2010)
Lipids
, vol.45
, pp. 209-224
-
-
Kitson, A.P.1
Stroud, C.K.2
Stark, K.D.3
-
63
-
-
0028321529
-
Differential expression and activation of a family of murine peroxisome proliferator-activated receptors
-
Kliewer SA, Forman BM, Blumberg B, Ong ES, Borgmeyer U, Mangelsdorf DJ, Umesono K, Evans RM (1994) Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci USA 91:7355-7359
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7355-7359
-
-
Kliewer, S.A.1
Forman, B.M.2
Blumberg, B.3
Ong, E.S.4
Borgmeyer, U.5
Mangelsdorf, D.J.6
Umesono, K.7
Evans, R.M.8
-
65
-
-
0030985318
-
Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay
-
Krey G, Braissant O, L'Horset F, Kalkhoven E, Perroud M, Parker MG, Wahli W (1997) Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol Endocrinol 11:779-791
-
(1997)
Mol Endocrinol
, vol.11
, pp. 779-791
-
-
Krey, G.1
Braissant, O.2
L'Horset, F.3
Kalkhoven, E.4
Perroud, M.5
Parker, M.G.6
Wahli, W.7
-
66
-
-
34250847265
-
Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone
-
Lazarenko OP, Rzonca SO, Hogue WR, Swain FL, Suva LJ, Lecka-Czernik B (2007) Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone. Endocrinology 148:2669-2680
-
(2007)
Endocrinology
, vol.148
, pp. 2669-2680
-
-
Lazarenko, O.P.1
Rzonca, S.O.2
Hogue, W.R.3
Swain, F.L.4
Suva, L.J.5
Lecka-Czernik, B.6
-
67
-
-
77955984749
-
PPARs in bone: The role in bone cell differentiation and regulation of energy metabolism
-
Lecka-Czernik B (2010) PPARs in bone: the role in bone cell differentiation and regulation of energy metabolism. Curr Osteoporos Rep 8:84-90
-
(2010)
Curr Osteoporos Rep
, vol.8
, pp. 84-90
-
-
Lecka-Czernik, B.1
-
68
-
-
0028997684
-
Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
-
Lee SS, Pineau T, Drago J, Lee EJ, Owens JW, Kroetz DL, Fernandez-Salguero PM, Westphal H, Gonzalez FJ (1995) Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol 15:3012-3022
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3012-3022
-
-
Lee, S.S.1
Pineau, T.2
Drago, J.3
Lee, E.J.4
Owens, J.W.5
Kroetz, D.L.6
Fernandez-Salguero, P.M.7
Westphal, H.8
Gonzalez, F.J.9
-
69
-
-
33644652183
-
Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis
-
Lefebvre P, Chinetti G, Fruchart JC, Staels B (2006) Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis. J Clin Invest 116:571-580
-
(2006)
J Clin Invest
, vol.116
, pp. 571-580
-
-
Lefebvre, P.1
Chinetti, G.2
Fruchart, J.C.3
Staels, B.4
-
70
-
-
34548590934
-
Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: A meta-analysis of randomized trials
-
Lincoff AM, Wolski K, Nicholls SJ, Nissen SE (2007) Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized trials. JAMA 298:1180-1188
-
(2007)
JAMA
, vol.298
, pp. 1180-1188
-
-
Lincoff, A.M.1
Wolski, K.2
Nicholls, S.J.3
Nissen, S.E.4
-
71
-
-
58849094131
-
Long-term use of thiazolidinediones and fractures in type 2 diabetes: A meta-analysis
-
Loke YK, Singh S, Furberg CD (2009) Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis. CMAJ 180:32-39
-
(2009)
CMAJ
, vol.180
, pp. 32-39
-
-
Loke, Y.K.1
Singh, S.2
Furberg, C.D.3
-
72
-
-
33646133406
-
The expanding cosmos of nuclear receptor coactivators
-
Lonard DM, O'Malley BW (2006) The expanding cosmos of nuclear receptor coactivators. Cell 125:411-414
-
(2006)
Cell
, vol.125
, pp. 411-414
-
-
Lonard, D.M.1
O'Malley, B.W.2
-
73
-
-
0033305094
-
Titration by estrogen receptor activation function-2 of targets that are downstream from coactivators
-
Lopez GN, Webb P, Shinsako JH, Baxter JD, Greene GL, Kushner PJ (1999) Titration by estrogen receptor activation function-2 of targets that are downstream from coactivators. Mol Endocrinol 13:897-909
-
(1999)
Mol Endocrinol
, vol.13
, pp. 897-909
-
-
Lopez, G.N.1
Webb, P.2
Shinsako, J.H.3
Baxter, J.D.4
Greene, G.L.5
Kushner, P.J.6
-
74
-
-
67651246719
-
Sex differences in global mRNA content of human skeletal muscle
-
Maher AC, Fu MH, Isfort RJ, Varbanov AR, Qu XA, Tarnopolsky MA (2009) Sex differences in global mRNA content of human skeletal muscle. PLoS One 4:e6335
-
(2009)
PLoS One
, vol.4
-
-
Maher, A.C.1
Fu, M.H.2
Isfort, R.J.3
Varbanov, A.R.4
Qu, X.A.5
Tarnopolsky, M.A.6
-
75
-
-
77957778868
-
Women have higher protein content of beta-oxidation enzymes in skeletal muscle than men
-
Maher AC, Akhtar M, Vockley J, Tarnopolsky MA (2010) Women have higher protein content of beta-oxidation enzymes in skeletal muscle than men. PLoS One 5:e12025
-
(2010)
PLoS One
, vol.5
-
-
Maher, A.C.1
Akhtar, M.2
Vockley, J.3
Tarnopolsky, M.A.4
-
76
-
-
0035936883
-
Fenofibrate prevents and reduces body weight gain and adiposity in diet-induced obese rats
-
Mancini FP, Lanni A, Sabatino L, Moreno M, Giannino A, Contaldo F, Colantuoni V, Goglia F (2001) Fenofibrate prevents and reduces body weight gain and adiposity in diet-induced obese rats. FEBS Lett 491:154-158
-
(2001)
FEBS Lett
, vol.491
, pp. 154-158
-
-
Mancini, F.P.1
Lanni, A.2
Sabatino, L.3
Moreno, M.4
Giannino, A.5
Contaldo, F.6
Colantuoni, V.7
Goglia, F.8
-
77
-
-
1542283630
-
Peroxisome proliferator-activated receptor alpha target genes
-
Mandard S, Muller M, Kersten S (2004) Peroxisome proliferator-activated receptor alpha target genes. Cell Mol Life Sci 61:393-416
-
(2004)
Cell Mol Life Sci
, vol.61
, pp. 393-416
-
-
Mandard, S.1
Muller, M.2
Kersten, S.3
-
78
-
-
77954356742
-
Cardiac safety profile of rosiglitazone: A comprehensive meta-analysis of randomized clinical trials
-
Mannucci E, Monami M, Di Bari M, Lamanna C, Gori F, Gensini GF, Marchionni N (2010) Cardiac safety profile of rosiglitazone: a comprehensive meta-analysis of randomized clinical trials. Int J Cardiol 143:135-140
-
(2010)
Int J Cardiol
, vol.143
, pp. 135-140
-
-
Mannucci, E.1
Monami, M.2
Di Bari, M.3
Lamanna, C.4
Gori, F.5
Gensini, G.F.6
Marchionni, N.7
-
79
-
-
0025636233
-
Lipoproteins and coronary heart disease in the helsinki heart study
-
Manttari M, Huttunen JK, Koskinen P, Manninen V, Tenkanen L, Heinonen OP, Frick MH (1990) Lipoproteins and coronary heart disease in the Helsinki Heart Study. Eur Heart J 11(Suppl H):26-31
-
(1990)
Eur Heart J
, vol.11
, Issue.SUPPL. H
, pp. 26-31
-
-
Manttari, M.1
Huttunen, J.K.2
Koskinen, P.3
Manninen, V.4
Tenkanen, L.5
Heinonen, O.P.6
Frick, M.H.7
-
80
-
-
0034607051
-
Inhibitory effect of a proline-to-alanine substitution at codon 12 of peroxisome proliferator-activated receptor-gamma 2 on thiazolidinedione-induced adipogenesis
-
Masugi J, Tamori Y, Mori H, Koike T, Kasuga M (2000) Inhibitory effect of a proline-to-alanine substitution at codon 12 of peroxisome proliferator-activated receptor-gamma 2 on thiazolidinedione-induced adipogenesis. Biochem Biophys Res Commun 268:178-182
-
(2000)
Biochem Biophys Res Commun
, vol.268
, pp. 178-182
-
-
Masugi, J.1
Tamori, Y.2
Mori, H.3
Koike, T.4
Kasuga, M.5
-
81
-
-
34547768729
-
Effects of a PPARG gene variant on obesity characteristics in Brazil
-
Mattevi VS, Zembrzuski VM, Hutz MH (2007) Effects of a PPARG gene variant on obesity characteristics in Brazil. Braz J Med Biol Res 40:927-932
-
(2007)
Braz J Med Biol Res
, vol.40
, pp. 927-932
-
-
Mattevi, V.S.1
Zembrzuski, V.M.2
Hutz, M.H.3
-
82
-
-
0037154974
-
Combinatorial control of gene expression by nuclear receptors and coregulators
-
McKenna NJ, O'Malley BW (2002) Combinatorial control of gene expression by nuclear receptors and coregulators. Cell 108:465-474
-
(2002)
Cell
, vol.108
, pp. 465-474
-
-
McKenna, N.J.1
O'Malley, B.W.2
-
83
-
-
44449120021
-
Interaction between PPARgamma2 variants and gender on the modulation of body weight
-
Morini E, Tassi V, Capponi D, Ludovico O, Dallapiccola B, Trischitta V, Prudente S (2008) Interaction between PPARgamma2 variants and gender on the modulation of body weight. Obesity (Silver Spring) 16:1467-1470
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 1467-1470
-
-
Morini, E.1
Tassi, V.2
Capponi, D.3
Ludovico, O.4
Dallapiccola, B.5
Trischitta, V.6
Prudente, S.7
-
84
-
-
0037140679
-
Effects of a lipid lowering fibrate and hormone replacement therapy on serum lipids and lipoproteins in overweight postmenopausal women with elevated triglycerides
-
Nerbrand C, Nyberg P, Nordstrom L, Samsioe G (2002) Effects of a lipid lowering fibrate and hormone replacement therapy on serum lipids and lipoproteins in overweight postmenopausal women with elevated triglycerides. Maturitas 42:55-62
-
(2002)
Maturitas
, vol.42
, pp. 55-62
-
-
Nerbrand, C.1
Nyberg, P.2
Nordstrom, L.3
Samsioe, G.4
-
85
-
-
34250212715
-
Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
-
Nissen SE, Wolski K (2007) Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 356:2457-2471
-
(2007)
N Engl J Med
, vol.356
, pp. 2457-2471
-
-
Nissen, S.E.1
Wolski, K.2
-
86
-
-
0035942162
-
A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport
-
Oliver WR Jr, Shenk JL, Snaith MR, Russell CS, Plunket KD, Bodkin NL, Lewis MC, Winegar DA, Sznaidman ML, Lambert MH et al (2001) A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport. Proc Natl Acad Sci USA 98:5306-5311
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5306-5311
-
-
Oliver Jr., W.R.1
Shenk, J.L.2
Snaith, M.R.3
Russell, C.S.4
Plunket, K.D.5
Bodkin, N.L.6
Lewis, M.C.7
Winegar, D.A.8
Sznaidman, M.L.9
Lambert, M.H.10
-
87
-
-
0031952238
-
Peroxisome proliferator activated receptor-alpha expression in human liver
-
Palmer CN, Hsu MH, Griffin KJ, Raucy JL, Johnson EF (1998) Peroxisome proliferator activated receptor-alpha expression in human liver. Mol Pharmacol 53:14-22
-
(1998)
Mol Pharmacol
, vol.53
, pp. 14-22
-
-
Palmer, C.N.1
Hsu, M.H.2
Griffin, K.J.3
Raucy, J.L.4
Johnson, E.F.5
-
88
-
-
0033123466
-
Rosiglitazone monotherapy improves glycaemic control in patients with type 2 diabetes: A twelve-week, randomized, placebo-controlled study
-
Patel J, Anderson RJ, Rappaport EB (1999) Rosiglitazone monotherapy improves glycaemic control in patients with type 2 diabetes: a twelve-week, randomized, placebo-controlled study. Diabetes Obes Metab 1:165-172
-
(1999)
Diabetes Obes Metab
, vol.1
, pp. 165-172
-
-
Patel, J.1
Anderson, R.J.2
Rappaport, E.B.3
-
90
-
-
33751335302
-
Factors associated with the effect-size of thiazolidinedione (TZD) therapy on HbA(1c): A meta-analysis of published randomized clinical trials
-
Phatak HM, Yin DD (2006) Factors associated with the effect-size of thiazolidinedione (TZD) therapy on HbA(1c): a meta-analysis of published randomized clinical trials. Curr Med Res Opin 22:2267-2278
-
(2006)
Curr Med Res Opin
, vol.22
, pp. 2267-2278
-
-
Phatak, H.M.1
Yin, D.D.2
-
91
-
-
0036399805
-
PPAR(gamma) and glucose homeostasis
-
Picard F, Auwerx J (2002) PPAR(gamma) and glucose homeostasis. Annu Rev Nutr 22:167-197
-
(2002)
Annu Rev Nutr
, vol.22
, pp. 167-197
-
-
Picard, F.1
Auwerx, J.2
-
92
-
-
2442635417
-
Peroxisome proliferators and peroxisome proliferator-activated receptor alpha: Biotic and xenobiotic sensing
-
Reddy JK (2004) Peroxisome proliferators and peroxisome proliferator-activated receptor alpha: biotic and xenobiotic sensing. Am J Pathol 164:2305-2321
-
(2004)
Am J Pathol
, vol.164
, pp. 2305-2321
-
-
Reddy, J.K.1
-
93
-
-
17744374490
-
Additive effects of the PPARgamma, APOE, and FABP-2 genes in increasing daylong triglycerides of normolipidemic women to concentrations comparable to those in men
-
Ribalta J, Halkes CJ, Salazar J, Masana L, Cabezas MC (2005) Additive effects of the PPARgamma, APOE, and FABP-2 genes in increasing daylong triglycerides of normolipidemic women to concentrations comparable to those in men. Clin Chem 51:864-871
-
(2005)
Clin Chem
, vol.51
, pp. 864-871
-
-
Ribalta, J.1
Halkes, C.J.2
Salazar, J.3
Masana, L.4
Cabezas, M.C.5
-
95
-
-
33751171107
-
Sex differences in hormone-sensitive lipase expression, activity, and phosphorylation in skeletal muscle at rest and during exercise
-
Roepstorff C, Donsmark M, Thiele M, Vistisen B, Stewart G, Vissing K, Schjerling P, Hardie DG, Galbo H, Kiens B (2006) Sex differences in hormone-sensitive lipase expression, activity, and phosphorylation in skeletal muscle at rest and during exercise. Am J Physiol 291: E1106-E1114
-
(2006)
Am J Physiol
, vol.291
-
-
Roepstorff, C.1
Donsmark, M.2
Thiele, M.3
Vistisen, B.4
Stewart, G.5
Vissing, K.6
Schjerling, P.7
Hardie, D.G.8
Galbo, H.9
Kiens, B.10
-
96
-
-
66449086930
-
Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity
-
Rogers NH, Perfield JW 2nd, Strissel KJ, Obin MS, Greenberg AS (2009) Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity. Endocrinology 150:2161-2168
-
(2009)
Endocrinology
, vol.150
, pp. 2161-2168
-
-
Rogers, N.H.1
Perfield II, J.W.2
Strissel, K.J.3
Obin, M.S.4
Greenberg, A.S.5
-
97
-
-
0036084660
-
Abdominal adiposity and insulin resistance in obese men
-
Ross R, Aru J, Freeman J, Hudson R, Janssen I (2002) Abdominal adiposity and insulin resistance in obese men. Am J Physiol 282:E657-E663
-
(2002)
Am J Physiol
, vol.282
-
-
Ross, R.1
Aru, J.2
Freeman, J.3
Hudson, R.4
Janssen, I.5
-
98
-
-
0033527030
-
Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol
-
Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group
-
Rubins HB, Robins SJ, Collins D, Fye CL, Anderson JW, Elam MB, Faas FH, Linares E, Schaefer EJ, Schectman G et al (1999) Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. N Engl J Med 341:410-418
-
(1999)
N Engl J Med
, vol.341
, pp. 410-418
-
-
Rubins, H.B.1
Robins, S.J.2
Collins, D.3
Fye, C.L.4
Anderson, J.W.5
Elam, M.B.6
Faas, F.H.7
Linares, E.8
Schaefer, E.J.9
Schectman, G.10
-
99
-
-
0032533219
-
Treatment effects on serum lipoprotein lipids, apolipoproteins and low density lipoprotein particle size and relationships of lipoprotein variables to progression of coronary artery disease in the bezafibrate coronary atherosclerosis intervention trial (BECAIT)
-
Ruotolo G, Ericsson CG, Tettamanti C, Karpe F, Grip L, Svane B, Nilsson J, de Faire U, Hamsten A (1998) Treatment effects on serum lipoprotein lipids, apolipoproteins and low density lipoprotein particle size and relationships of lipoprotein variables to progression of coronary artery disease in the Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT). J Am Coll Cardiol 32:1648-1656
-
(1998)
J Am Coll Cardiol
, vol.32
, pp. 1648-1656
-
-
Ruotolo, G.1
Ericsson, C.G.2
Tettamanti, C.3
Karpe, F.4
Grip, L.5
Svane, B.6
Nilsson, J.7
De Faire, U.8
Hamsten, A.9
-
100
-
-
77958529709
-
Cardiovascular risk and thiazolidinediones-what do meta-analyses really tell us?
-
Schernthaner G, Chilton RJ (2010) Cardiovascular risk and thiazolidinediones-what do meta-analyses really tell us? Diabetes Obes Metab 12:1023-1035
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 1023-1035
-
-
Schernthaner, G.1
Chilton, R.J.2
-
102
-
-
34548580881
-
Long-term risk of cardiovascular events with rosiglitazone: A meta-analysis
-
Singh S, Loke YK, Furberg CD (2007) Long-term risk of cardiovascular events with rosiglitazone: a meta-analysis. JAMA 298:1189-1195
-
(2007)
JAMA
, vol.298
, pp. 1189-1195
-
-
Singh, S.1
Loke, Y.K.2
Furberg, C.D.3
-
103
-
-
79960799930
-
Low high-density lipoprotein cholesterol: Current status and future strategies for management
-
Singh V, Sharma R, Kumar A, Deedwania P (2010) Low high-density lipoprotein cholesterol: current status and future strategies for management. Vasc Health Risk Manag 6:979-996
-
(2010)
Vasc Health Risk Manag
, vol.6
, pp. 979-996
-
-
Singh, V.1
Sharma, R.2
Kumar, A.3
Deedwania, P.4
-
104
-
-
0032506273
-
Mechanism of action of fibrates on lipid and lipoprotein metabolism
-
Staels B, Dallongeville J, Auwerx J, Schoonjans K, Leitersdorf E, Fruchart JC (1998) Mechanism of action of fibrates on lipid and lipoprotein metabolism. Circulation 98:2088-2093
-
(1998)
Circulation
, vol.98
, pp. 2088-2093
-
-
Staels, B.1
Dallongeville, J.2
Auwerx, J.3
Schoonjans, K.4
Leitersdorf, E.5
Fruchart, J.C.6
-
105
-
-
36049034344
-
Anti-inflammatory actions of PPAR ligands: New insights on cellular and molecular mechanisms
-
Straus DS, Glass CK (2007) Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms. Trends Immunol 28:551-558
-
(2007)
Trends Immunol
, vol.28
, pp. 551-558
-
-
Straus, D.S.1
Glass, C.K.2
-
106
-
-
0026671184
-
Sex-dependent expression and clofibrate inducibility of cytochrome P450 4A fatty acid omega-hydroxylases. Male specificity of liver and kidney CYP4A2 mRNA and tissue-specific regulation by growth hormone and testosterone
-
Sundseth SS, Waxman DJ (1992) Sex-dependent expression and clofibrate inducibility of cytochrome P450 4A fatty acid omega-hydroxylases. Male specificity of liver and kidney CYP4A2 mRNA and tissue-specific regulation by growth hormone and testosterone. J Biol Chem 267:3915-3921
-
(1992)
J Biol Chem
, vol.267
, pp. 3915-3921
-
-
Sundseth, S.S.1
Waxman, D.J.2
-
107
-
-
0031080568
-
A study to determine the response of coronary atherosclerosis to raising low high density lipoprotein cholesterol with a fibric-acid derivative in men after coronary bypass surgery. The rationale, design, and baseline characteristics of the LOCAT study
-
Lopid Coronary Angiography Trial
-
Syvanne M, Taskinen MR, Nieminen, Manninen V, Kesaniemi YA, Pasternack A, Nawrocki JW, Haber H, and Frick MH (1997) A study to determine the response of coronary atherosclerosis to raising low high density lipoprotein cholesterol with a fibric-acid derivative in men after coronary bypass surgery. The rationale, design, and baseline characteristics of the LOCAT Study. Lopid Coronary Angiography Trial. Control Clin Trials 18:93-119
-
(1997)
Control Clin Trials
, vol.18
, pp. 93-119
-
-
Syvanne, M.1
Taskinen, M.R.2
Nieminen3
Manninen, V.4
Kesaniemi, Y.A.5
Pasternack, A.6
Nawrocki, J.W.7
Haber, H.8
Frick, M.H.9
-
108
-
-
40949147435
-
Sex differences in exercise metabolism and the role of 17-beta estradiol
-
Tarnopolsky MA (2008) Sex differences in exercise metabolism and the role of 17-beta estradiol. Med Sci Sports Exerc 40:648-654
-
(2008)
Med Sci Sports Exerc
, vol.40
, pp. 648-654
-
-
Tarnopolsky, M.A.1
-
109
-
-
33747818266
-
Nuclear receptors as drug targets in metabolic diseases: New approaches to therapy
-
Tobin JF, Freedman LP (2006) Nuclear receptors as drug targets in metabolic diseases: new approaches to therapy. Trends Endocrinol Metab 17:284-290
-
(2006)
Trends Endocrinol Metab
, vol.17
, pp. 284-290
-
-
Tobin, J.F.1
Freedman, L.P.2
-
110
-
-
0033591032
-
Up-regulation of liver uncoupling protein-2 mRNA by either fish oil feeding or fibrate administration in mice
-
Tsuboyama-Kasaoka N, Takahashi M, Kim H, Ezaki O (1999) Up-regulation of liver uncoupling protein-2 mRNA by either fish oil feeding or fibrate administration in mice. Biochem Biophys Res Commun 257:879-885
-
(1999)
Biochem Biophys Res Commun
, vol.257
, pp. 879-885
-
-
Tsuboyama-Kasaoka, N.1
Takahashi, M.2
Kim, H.3
Ezaki, O.4
-
111
-
-
0033816008
-
Pro12Ala mutation in the peroxisome proliferator-activated receptor gamma2 (PPARgamma2) and severe obesity: A case-control study
-
Vaccaro O, Mancini FP, Ruffa G, Sabatino L, Colantuoni V, Riccardi G (2000) Pro12Ala mutation in the peroxisome proliferator-activated receptor gamma2 (PPARgamma2) and severe obesity: a case-control study. Int J Obes Relat Metab Disord 24:1195-1199
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, pp. 1195-1199
-
-
Vaccaro, O.1
Mancini, F.P.2
Ruffa, G.3
Sabatino, L.4
Colantuoni, V.5
Riccardi, G.6
-
112
-
-
44149122469
-
The clinical reality of guidelines for primary prevention of cardiovascular disease in type 2 diabetes in Italy
-
Vaccaro O, Boemi M, Cavalot F, De Feo P, Miccoli R, Patti L, Rivellese AA, Trovati M, Ardigo D, Zavaroni I (2008) The clinical reality of guidelines for primary prevention of cardiovascular disease in type 2 diabetes in Italy. Atherosclerosis 198:396-402
-
(2008)
Atherosclerosis
, vol.198
, pp. 396-402
-
-
Vaccaro, O.1
Boemi, M.2
Cavalot, F.3
De Feo, P.4
Miccoli, R.5
Patti, L.6
Rivellese, A.A.7
Trovati, M.8
Ardigo, D.9
Zavaroni, I.10
-
113
-
-
0037426396
-
Relationships between low-density lipoprotein particle size, plasma lipoproteins, and progression of coronary artery disease: The diabetes atherosclerosis intervention study (DAIS)
-
Vakkilainen J, Steiner G, Ansquer JC, Aubin F, Rattier S, Foucher C, Hamsten A, Taskinen MR (2003) Relationships between low-density lipoprotein particle size, plasma lipoproteins, and progression of coronary artery disease: the Diabetes Atherosclerosis Intervention Study (DAIS). Circulation 107:1733-1737
-
(2003)
Circulation
, vol.107
, pp. 1733-1737
-
-
Vakkilainen, J.1
Steiner, G.2
Ansquer, J.C.3
Aubin, F.4
Rattier, S.5
Foucher, C.6
Hamsten, A.7
Taskinen, M.R.8
-
114
-
-
78650609247
-
Hypoglycaemia with pioglitazone: Analysis of data from the prescription-event monitoring study
-
Vlckova V, Cornelius V, Kasliwal R, Wilton L, Shakir S (2010) Hypoglycaemia with pioglitazone: analysis of data from the Prescription-Event Monitoring study. J Eval Clin Pract 16:1124-1128
-
(2010)
J Eval Clin Pract
, vol.16
, pp. 1124-1128
-
-
Vlckova, V.1
Cornelius, V.2
Kasliwal, R.3
Wilton, L.4
Shakir, S.5
-
115
-
-
36849034568
-
PPAR-gamma regulates osteoclastogenesis in mice
-
Wan Y, Chong LW, Evans RM (2007) PPAR-gamma regulates osteoclastogenesis in mice. Nat Med 13:1496-1503
-
(2007)
Nat Med
, vol.13
, pp. 1496-1503
-
-
Wan, Y.1
Chong, L.W.2
Evans, R.M.3
-
116
-
-
0037200657
-
Signal cross-talk between estrogen receptor alpha and beta and the peroxisome proliferator-activated receptor gamma1 in MDA-MB-231 and MCF-7 breast cancer cells
-
Wang X, Kilgore MW (2002) Signal cross-talk between estrogen receptor alpha and beta and the peroxisome proliferator-activated receptor gamma1 in MDA-MB-231 and MCF-7 breast cancer cells. Mol Cell Endocrinol 194:123-133
-
(2002)
Mol Cell Endocrinol
, vol.194
, pp. 123-133
-
-
Wang, X.1
Kilgore, M.W.2
-
117
-
-
0037453718
-
Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity
-
Wang YX, Lee CH, Tiep S, Yu RT, Ham J, Kang H, Evans RM (2003) Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell 113:159-170
-
(2003)
Cell
, vol.113
, pp. 159-170
-
-
Wang, Y.X.1
Lee, C.H.2
Tiep, S.3
Yu, R.T.4
Ham, J.5
Kang, H.6
Evans, R.M.7
-
118
-
-
77952293181
-
Troglitazone is an estrogen-related receptor alpha and gamma inverse agonist
-
Wang Y, Fang F, Wong CW (2010) Troglitazone is an estrogen-related receptor alpha and gamma inverse agonist. Biochem Pharmacol 80:80-85
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 80-85
-
-
Wang, Y.1
Fang, F.2
Wong, C.W.3
-
119
-
-
77956408841
-
PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss
-
Wei W, Wang X, Yang M, Smith LC, Dechow PC, Sonoda J, Evans RM, Wan Y (2010) PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss. Cell Metab 11:503-516
-
(2010)
Cell Metab
, vol.11
, pp. 503-516
-
-
Wei, W.1
Wang, X.2
Yang, M.3
Smith, L.C.4
Dechow, P.C.5
Sonoda, J.6
Evans, R.M.7
Wan, Y.8
-
120
-
-
0345164399
-
Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic caucasians: Identification of a pro12ala PPAR gamma 2 missense mutation
-
Yen CJ, Beamer BA, Negri C, Silver K, Brown KA, Yarnall DP, Burns DK, Roth J, Shuldiner AR (1997) Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic Caucasians: identification of a Pro12Ala PPAR gamma 2 missense mutation. Biochem Biophys Res Commun 241:270-274
-
(1997)
Biochem Biophys Res Commun
, vol.241
, pp. 270-274
-
-
Yen, C.J.1
Beamer, B.A.2
Negri, C.3
Silver, K.4
Brown, K.A.5
Yarnall, D.P.6
Burns, D.K.7
Roth, J.8
Shuldiner, A.R.9
-
121
-
-
77957768699
-
Estrogen receptor-ibeta}-selective ligands alleviate high-fat diet- and ovariectomy-induced obesity in mice
-
Yepuru M, Eswaraka J, Kearbey JD, Barrett CM, Raghow S, Veverka KA, Miller DD, Dalton JT, Narayanan R (2010) Estrogen receptor-ibeta}-selective ligands alleviate high-fat diet- and ovariectomy-induced obesity in mice. J Biol Chem 285:31292-31303
-
(2010)
J Biol Chem
, vol.285
, pp. 31292-31303
-
-
Yepuru, M.1
Eswaraka, J.2
Kearbey, J.D.3
Barrett, C.M.4
Raghow, S.5
Veverka, K.A.6
Miller, D.D.7
Dalton, J.T.8
Narayanan, R.9
-
122
-
-
19244365650
-
Thiazolidinediones
-
Yki-Jarvinen H (2004) Thiazolidinediones. N Engl J Med 351:1106-1118
-
(2004)
N Engl J Med
, vol.351
, pp. 1106-1118
-
-
Yki-Jarvinen, H.1
-
123
-
-
0037207240
-
Fenofibrate regulates obesity and lipid metabolism with sexual dimorphism
-
Yoon M, Jeong S, Nicol CJ, Lee H, Han M, Kim JJ, Seo YJ, Ryu C, Oh GT (2002) Fenofibrate regulates obesity and lipid metabolism with sexual dimorphism. Exp Mol Med 34:481-488
-
(2002)
Exp Mol Med
, vol.34
, pp. 481-488
-
-
Yoon, M.1
Jeong, S.2
Nicol, C.J.3
Lee, H.4
Han, M.5
Kim, J.J.6
Seo, Y.J.7
Ryu, C.8
Oh, G.T.9
-
124
-
-
27644457743
-
Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: A case-control study
-
Yusuf S, Hawken S, Ounpuu S, Bautista L, Franzosi MG, Commerford P, Lang CC, Rumboldt Z, Onen CL, Lisheng L et al (2005) Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study. Lancet 366:1640-1649
-
(2005)
Lancet
, vol.366
, pp. 1640-1649
-
-
Yusuf, S.1
Hawken, S.2
Ounpuu, S.3
Bautista, L.4
Franzosi, M.G.5
Commerford, P.6
Lang, C.C.7
Rumboldt, Z.8
Onen, C.L.9
Lisheng, L.10
|