Quantitation of asparagine deamidation by isotope labeling and liquid chromatography coupled with mass spectrometry analysis

Analytical Biochemistry

Volumn 432, Issue 1, 2013, Pages 16-22

  Liu, Hongcheng ^a   Wang, Fengqiang ^a   Xu, Wei ^a   May, Kimberly ^a   Richardson, Daisy ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Deamidation; Isotope labeling; Mass spectrometry

Indexed keywords

AMINO ACIDS; CHEMICAL REACTIONS; ISOTOPES; MASS SPECTROMETERS; MASS SPECTROMETRY; PEPTIDES;

ANALYTICAL ARTIFACT; CALCULATION PROCEDURE; DATA INTERPRETATION; DEAMIDATION; ISOTOPE LABELING; LABELING PROCEDURES; MASS SPECTROMETRY ANALYSIS; POST-TRANSLATIONAL MODIFICATIONS;

LIQUID CHROMATOGRAPHY;

ASPARAGINE; ASPARTIC ACID; CARBOXYL GROUP; ISOASPARTIC ACID; OXYGEN 18;

ARTICLE; CALCULATION; CARBOXY TERMINAL SEQUENCE; DEAMINATION; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REACTION ANALYSIS;

EID: 84868230100     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2012.09.024     Document Type: Article

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