Actopaxin (α-parvin) phosphorylation is required for matrix degradation and cancer cell invasion

Journal of Biological Chemistry

Volumn 287, Issue 44, 2012, Pages 37309-37320

  Pignatelli, Jeanine ^a   LaLonde, Sara E ^b   LaLonde, David P ^c   Clarke, Dominic ^d   Turner, Christopher E ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b Department of Obstetrics Gynecology   (United States)

^c School of Integrative Plant Sciences   (United States)

^d Department of Cellular Therapy   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTOPAXIN; CANCER CELLS; CELL INVASION; CONTROL MATRICES; INTEGRAL COMPONENTS;

CELLS;

PHOSPHORYLATION;

ACTOPAXIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MATRIX METALLOPROTEINASE; MYOSIN; P21 ACTIVATED KINASE; PAK INTERACTING EXCHANGE FACTOR; PAXILLIN; PROTEIN CDC42; PROTEIN TYROSINE KINASE; QUINT PROTEIN; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; S4D PROTEIN; S8D PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL; CANCER CELL CULTURE; CELL INVASION; CELL NUCLEUS MATRIX; CELL STRAIN MCF10A; CELL STRAIN MDA MB 231; CELL STRESS; COMPLEX FORMATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX DEGRADATION; HUMAN; HUMAN CELL; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WILD TYPE;

CELL LINE, TUMOR; CELL MOVEMENT; ENZYME INHIBITORS; EXTRACELLULAR MATRIX; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MATRIX METALLOPROTEINASES, SECRETED; MICROFILAMENT PROTEINS; MYOSINS; NEOPLASM INVASIVENESS; NEOPLASMS; P21-ACTIVATED KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; RAC1 GTP-BINDING PROTEIN; SRC-FAMILY KINASES;

EID: 84868217293     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.385229     Document Type: Article

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