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Volumn 121, Issue 3, 2008, Pages 369-378

Multiple regulatory inputs converge on cortactin to control invadopodia biogenesis and extracellular matrix degradation

Author keywords

Cortactin; Invadopodia; Invasion; Protein kinases

Indexed keywords

ACTIN RELATED PROTEIN 2-3 COMPLEX; CORTACTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN; P21 ACTIVATED KINASE 1; PROTEIN SH3; PROTEIN TYROSINE KINASE;

EID: 40549089536     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.008037     Document Type: Article
Times cited : (177)

References (74)
  • 1
    • 0036799301 scopus 로고    scopus 로고
    • Molecular proximity of seprase and the urokinase-type plasminogen activator receptor on malignant melanoma cell membranes: Dependence on betal integrins and the cytoskeleton
    • Artym, V. V., Kindzelskii, A. L., Chen, W. T. and Petty, H. R. (2002). Molecular proximity of seprase and the urokinase-type plasminogen activator receptor on malignant melanoma cell membranes: dependence on betal integrins and the cytoskeleton. Carcinogenesis 23, 1593-1601.
    • (2002) Carcinogenesis , vol.23 , pp. 1593-1601
    • Artym, V.V.1    Kindzelskii, A.L.2    Chen, W.T.3    Petty, H.R.4
  • 2
    • 33645507413 scopus 로고    scopus 로고
    • Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: Defining the stages of invadopodia formation and function
    • Artym, V. V., Zhang, Y., Sefillier-Moiseiwitsch, F., Yamada, K. M. and Mueller, S. C. (2006). Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function. Cancer Res. 66, 3034-3043.
    • (2006) Cancer Res , vol.66 , pp. 3034-3043
    • Artym, V.V.1    Zhang, Y.2    Sefillier-Moiseiwitsch, F.3    Yamada, K.M.4    Mueller, S.C.5
  • 3
    • 0346462998 scopus 로고    scopus 로고
    • p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells
    • Balasenthil, S., Sahin, A. A., Barnes, C. J., Wang, R. A., Pestell, R. G., Vadlamudi, R. K. and Kumar, R. (2004). p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells. J. Biol. Chem. 279, 1422-1428.
    • (2004) J. Biol. Chem , vol.279 , pp. 1422-1428
    • Balasenthil, S.1    Sahin, A.A.2    Barnes, C.J.3    Wang, R.A.4    Pestell, R.G.5    Vadlamudi, R.K.6    Kumar, R.7
  • 7
    • 0038554077 scopus 로고    scopus 로고
    • Biology of the p21-activated kinases
    • Bokoch, G. M. (2003). Biology of the p21-activated kinases. Annu. Rev. Biochem. 72,743-781.
    • (2003) Annu. Rev. Biochem , vol.72 , pp. 743-781
    • Bokoch, G.M.1
  • 8
    • 0033527066 scopus 로고    scopus 로고
    • An invasion-related complex of cortactin, paxillin and PKCmu associates with invadopodia at sites of extracellular matrix degradation
    • Bowden, E. T., Barth, M., Thomas, D., Glazer, R. I. and Mueller, S. C. (1999). An invasion-related complex of cortactin, paxillin and PKCmu associates with invadopodia at sites of extracellular matrix degradation. Oncogene 18, 4440-4449.
    • (1999) Oncogene , vol.18 , pp. 4440-4449
    • Bowden, E.T.1    Barth, M.2    Thomas, D.3    Glazer, R.I.4    Mueller, S.C.5
  • 9
    • 0035227262 scopus 로고    scopus 로고
    • Invadopodia: Unique methods for measurement of extracellular matrix degradation in vitro
    • Bowden, E. T., Coopman, P. J. and Mueller, S. C. (2001). Invadopodia: unique methods for measurement of extracellular matrix degradation in vitro. Methods Cell Biol. 63, 613-627.
    • (2001) Methods Cell Biol , vol.63 , pp. 613-627
    • Bowden, E.T.1    Coopman, P.J.2    Mueller, S.C.3
  • 10
    • 33646071808 scopus 로고    scopus 로고
    • Co-localization of cortactin and phosphotyrosine identifies active invadopodia in human breast cancer cells
    • Bowden, E. T., Onikoyi, E., Slack, R., Myoui, A., Yuneda, T., Yamada, K. M. and Mueller, S. C. (2006). Co-localization of cortactin and phosphotyrosine identifies active invadopodia in human breast cancer cells. Exp, Cell Res. 312, 1240-1253.
    • (2006) Exp, Cell Res , vol.312 , pp. 1240-1253
    • Bowden, E.T.1    Onikoyi, E.2    Slack, R.3    Myoui, A.4    Yuneda, T.5    Yamada, K.M.6    Mueller, S.C.7
  • 11
    • 33847284434 scopus 로고    scopus 로고
    • A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation
    • Boyle, S. N., Michaud, G. A., Schweitzer, B., Predki, P. F. and Koleske, A. J. (2007). A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation. Carr. Biol. 17, 445-451.
    • (2007) Carr. Biol , vol.17 , pp. 445-451
    • Boyle, S.N.1    Michaud, G.A.2    Schweitzer, B.3    Predki, P.F.4    Koleske, A.J.5
  • 12
    • 0029917008 scopus 로고    scopus 로고
    • Expression of cyclin D1 and EMS1 in bladder tumours; relationship with chromosome 11q13 amplification
    • Bringuier, P. P., Tamimi, Y., Schuuring, E. and Schalken, J. (1996). Expression of cyclin D1 and EMS1 in bladder tumours; relationship with chromosome 11q13 amplification. Oncogene 12, 1747-1753.
    • (1996) Oncogene , vol.12 , pp. 1747-1753
    • Bringuier, P.P.1    Tamimi, Y.2    Schuuring, E.3    Schalken, J.4
  • 13
    • 0029188425 scopus 로고
    • Matrix metalloproteinase inhibitors: A novel class of anticancer agents
    • Brown, P. D. (1995). Matrix metalloproteinase inhibitors: a novel class of anticancer agents. Adv. Enzyme Regul. 35, 293-301.
    • (1995) Adv. Enzyme Regul , vol.35 , pp. 293-301
    • Brown, P.D.1
  • 14
    • 0029586589 scopus 로고
    • Matrix metalloproteinase inhibition: A review of anti-tumour activity
    • Brown, P. D. and Giavazzi, R. (1995). Matrix metalloproteinase inhibition: a review of anti-tumour activity. Ann. Oncol. 6, 967-974.
    • (1995) Ann. Oncol , vol.6 , pp. 967-974
    • Brown, P.D.1    Giavazzi, R.2
  • 15
    • 3543114271 scopus 로고    scopus 로고
    • Foot and mouth: Podosomes, invadopodia and circular dorsal ruffles
    • Buccione, R., Orth, J. D. and McNiven, M. A. (2004). Foot and mouth: podosomes, invadopodia and circular dorsal ruffles. Nat. Rev. Mol. Cell Biol. 5, 647-657.
    • (2004) Nat. Rev. Mol. Cell Biol , vol.5 , pp. 647-657
    • Buccione, R.1    Orth, J.D.2    McNiven, M.A.3
  • 16
    • 0032697492 scopus 로고    scopus 로고
    • Signaling pathways and structural domains required for phosphorylation of EMS1/cortactin
    • Campbell, D. H., Sutherland, R. L. and Daly, R. J. (1999). Signaling pathways and structural domains required for phosphorylation of EMS1/cortactin. Cancer Res. 59, 5376-5385.
    • (1999) Cancer Res , vol.59 , pp. 5376-5385
    • Campbell, D.H.1    Sutherland, R.L.2    Daly, R.J.3
  • 17
    • 18344381438 scopus 로고    scopus 로고
    • Actin and Arf1-dependent recruitment of a cortactin-dynamin complex to the Golgi regulates post-Golgi transport
    • Cao, H., Weller, S., Orth, J. D., Chen, J., Huang, B., Chen, J. L., Stamnes, M. and McNiven, M. A. (2005). Actin and Arf1-dependent recruitment of a cortactin-dynamin complex to the Golgi regulates post-Golgi transport. Nat. Cell Biol. 7, 483-492.
    • (2005) Nat. Cell Biol , vol.7 , pp. 483-492
    • Cao, H.1    Weller, S.2    Orth, J.D.3    Chen, J.4    Huang, B.5    Chen, J.L.6    Stamnes, M.7    McNiven, M.A.8
  • 19
    • 0024414571 scopus 로고
    • Proteolytic activity of specialized surface protrusions formed at rosette contact sites of transformed cells
    • Chen, W. T. (1989). Proteolytic activity of specialized surface protrusions formed at rosette contact sites of transformed cells. J. Exp. Zool. 251, 167-185.
    • (1989) J. Exp. Zool , vol.251 , pp. 167-185
    • Chen, W.T.1
  • 20
    • 0029999333 scopus 로고    scopus 로고
    • Proteases associated with invadopodia, and their role in degradation of extracellular matrix
    • Chen, W. T. (1996). Proteases associated with invadopodia, and their role in degradation of extracellular matrix. Enzyme Protein 49, 59-71.
    • (1996) Enzyme Protein , vol.49 , pp. 59-71
    • Chen, W.T.1
  • 21
    • 34249320529 scopus 로고    scopus 로고
    • Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia
    • Clark, E. S., Whigham, A. S., Yarbrough, W. G. and Weaver, A. M. (2007). Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia. Cancer Res. 67, 4227-4235.
    • (2007) Cancer Res , vol.67 , pp. 4227-4235
    • Clark, E.S.1    Whigham, A.S.2    Yarbrough, W.G.3    Weaver, A.M.4
  • 22
    • 27844455570 scopus 로고    scopus 로고
    • Mechanism of filament nucleation and branch stability revealed by the structure of the Arp2/3 complex at actin branch junctions
    • Egile, C., Rouiller, L, Xu, X. P., Volkmann, N., Li, R. and Hanein, D. (2005). Mechanism of filament nucleation and branch stability revealed by the structure of the Arp2/3 complex at actin branch junctions. PLoS Biol. 3, e383.
    • (2005) PLoS Biol , vol.3
    • Egile, C.1    Rouiller, L.2    Xu, X.P.3    Volkmann, N.4    Li, R.5    Hanein, D.6
  • 23
    • 34548133221 scopus 로고    scopus 로고
    • PKD is recruited to sites of actin remodelling at the leading edge and negatively regulates cell migration
    • Eiseler, T., Schmid, M. A., Topbas, F., Pfizenmaier, K. and Hausser, A. (2007). PKD is recruited to sites of actin remodelling at the leading edge and negatively regulates cell migration. FEBS Lett. 581, 4279-4287.
    • (2007) FEBS Lett , vol.581 , pp. 4279-4287
    • Eiseler, T.1    Schmid, M.A.2    Topbas, F.3    Pfizenmaier, K.4    Hausser, A.5
  • 26
    • 0037066778 scopus 로고    scopus 로고
    • v-Src SH3-enhanced interaction with focal adhesion kinase at beta 1 integrin-containing invadopodia promotes cell invasion
    • Hauck, C. R., Hsia, D. A., Ilic, D. and Schlaepfer, D. D. (2002). v-Src SH3-enhanced interaction with focal adhesion kinase at beta 1 integrin-containing invadopodia promotes cell invasion. J. Biol. Chem. 277, 12487-12490.
    • (2002) J. Biol. Chem , vol.277 , pp. 12487-12490
    • Hauck, C.R.1    Hsia, D.A.2    Ilic, D.3    Schlaepfer, D.D.4
  • 27
    • 0029942238 scopus 로고    scopus 로고
    • Association of a dynamin-like protein with the Golgi apparatus in mammalian cells
    • Henley, J. R. and McNiven, M. A. (1996). Association of a dynamin-like protein with the Golgi apparatus in mammalian cells. J. Cell Biol. 133, 761-775.
    • (1996) J. Cell Biol , vol.133 , pp. 761-775
    • Henley, J.R.1    McNiven, M.A.2
  • 28
    • 0030971098 scopus 로고    scopus 로고
    • Down-regulation of the filamentous actin cross-linking activity of cortactin by Src-mediated tyrosine phosphorylation
    • Huang, C., Ni, Y., Wang, T., Gao, Y., Haudenschild, C. C. and Zhan, X. (1997). Down-regulation of the filamentous actin cross-linking activity of cortactin by Src-mediated tyrosine phosphorylation. J. Biol. Chem. 272, 13911-13915.
    • (1997) J. Biol. Chem , vol.272 , pp. 13911-13915
    • Huang, C.1    Ni, Y.2    Wang, T.3    Gao, Y.4    Haudenschild, C.C.5    Zhan, X.6
  • 29
    • 0032476012 scopus 로고    scopus 로고
    • The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells
    • Huang, C., Liu, J., Haudenschild, C. C. and Zhan, X. (1998). The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells. J. Biol. Chem. 273, 25770-25776.
    • (1998) J. Biol. Chem , vol.273 , pp. 25770-25776
    • Huang, C.1    Liu, J.2    Haudenschild, C.C.3    Zhan, X.4
  • 31
    • 0028115933 scopus 로고
    • Invadopedia promote proteolysis of a wide variety of extracellular matrix proteins
    • Kelly, T., Mueller, S. C., Yeh, Y. and Chen, W. T. (1994). Invadopedia promote proteolysis of a wide variety of extracellular matrix proteins. J. Cell. Physiol. 158, 299-308.
    • (1994) J. Cell. Physiol , vol.158 , pp. 299-308
    • Kelly, T.1    Mueller, S.C.2    Yeh, Y.3    Chen, W.T.4
  • 32
    • 27644575157 scopus 로고    scopus 로고
    • Coordinating ERK/MAPK signalling through scaffolds and inhibitors
    • Kolch, W. (2005). Coordinating ERK/MAPK signalling through scaffolds and inhibitors. Nat. Rev. Mol. Cell Biol. 6, 827-837.
    • (2005) Nat. Rev. Mol. Cell Biol , vol.6 , pp. 827-837
    • Kolch, W.1
  • 33
    • 0021237842 scopus 로고
    • A human melanoma line heterogeneous with respect to metastatic capacity in athymic nude mice
    • Kozlowski, J. M., Hart, I. R., Fidler, I. J. and Hanna, N. (1984). A human melanoma line heterogeneous with respect to metastatic capacity in athymic nude mice. J. Natl. Cancer Inst. 72, 913-917.
    • (1984) J. Natl. Cancer Inst , vol.72 , pp. 913-917
    • Kozlowski, J.M.1    Hart, I.R.2    Fidler, I.J.3    Hanna, N.4
  • 34
    • 0037343053 scopus 로고    scopus 로고
    • A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells
    • Krueger, E. W., Orth, J. D., Cao, H. and McNiven, M. A. (2003). A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells. Mol. Biol. Cell 14, 1085-1096.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 1085-1096
    • Krueger, E.W.1    Orth, J.D.2    Cao, H.3    McNiven, M.A.4
  • 36
    • 0034711209 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of cortactin is required for H2O2-mediated injury of human endothelial cells
    • Li, Y., Liu, J. and Zhan, X. (2000). Tyrosine phosphorylation of cortactin is required for H2O2-mediated injury of human endothelial cells. J. Biol. Chem. 275, 37187-37193.
    • (2000) J. Biol. Chem , vol.275 , pp. 37187-37193
    • Li, Y.1    Liu, J.2    Zhan, X.3
  • 38
    • 0037441884 scopus 로고    scopus 로고
    • Amplification and overexpression of JUNB is associated with primary cutaneous T-cell lymphomas
    • Mao, X., Orchard, G., Lillington, D. M., Russell-Jones, R., Young, B. D. and Whittaker, S. J. (2003). Amplification and overexpression of JUNB is associated with primary cutaneous T-cell lymphomas. Blood 101, 1513-1519.
    • (2003) Blood , vol.101 , pp. 1513-1519
    • Mao, X.1    Orchard, G.2    Lillington, D.M.3    Russell-Jones, R.4    Young, B.D.5    Whittaker, S.J.6
  • 40
    • 2942594602 scopus 로고    scopus 로고
    • Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP
    • Martinez-Quiles, N., Ho, H. Y., Kirschner, M. W., Ramesh, N. and Geha, R. S. (2004). Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP. Mol. Cell. Biol. 24, 5269-5280.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 5269-5280
    • Martinez-Quiles, N.1    Ho, H.Y.2    Kirschner, M.W.3    Ramesh, N.4    Geha, R.S.5
  • 41
    • 0034597062 scopus 로고    scopus 로고
    • Regulated interactions between dynamin and the actin-binding protein cortactin modulate cell shape
    • McNiven, M. A., Kim, L., Krueger, E. W., Orth, J. D., Cao, H. and Wong, T. W. (2000). Regulated interactions between dynamin and the actin-binding protein cortactin modulate cell shape. J. Cell Biol. 151, 187-198.
    • (2000) J. Cell Biol , vol.151 , pp. 187-198
    • McNiven, M.A.1    Kim, L.2    Krueger, E.W.3    Orth, J.D.4    Cao, H.5    Wong, T.W.6
  • 42
    • 0036468250 scopus 로고    scopus 로고
    • Essential role of neural Wiskott-Aldrich syndrome protein in podosome formation and degradation of extracellular matrix in sre-transformed fibroblasts
    • Mizutani, K., Miki, H., He, H., Marutta, H. and Takenawa, T. (2002). Essential role of neural Wiskott-Aldrich syndrome protein in podosome formation and degradation of extracellular matrix in sre-transformed fibroblasts. Cancer Res. 62, 669-674.
    • (2002) Cancer Res , vol.62 , pp. 669-674
    • Mizutani, K.1    Miki, H.2    He, H.3    Marutta, H.4    Takenawa, T.5
  • 43
    • 0028152543 scopus 로고
    • A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells
    • Monsky, W. L., Lin, C. Y., Aoyama, A., Kelly, T., Akiyama, S. K., Mueller, S. C. and Chen, W. T. (1994). A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells. Cancer Res. 54, 5702-5710.
    • (1994) Cancer Res , vol.54 , pp. 5702-5710
    • Monsky, W.L.1    Lin, C.Y.2    Aoyama, A.3    Kelly, T.4    Akiyama, S.K.5    Mueller, S.C.6    Chen, W.T.7
  • 44
    • 0025853849 scopus 로고
    • Cellular invasion into matrix heads: Localization of beta 1 integrins and fibronectin to the invadopodia
    • Mueller, S. C. and Chen, W. T. (1991). Cellular invasion into matrix heads: localization of beta 1 integrins and fibronectin to the invadopodia. J. Cell Sci. 99, 213-225.
    • (1991) J. Cell Sci , vol.99 , pp. 213-225
    • Mueller, S.C.1    Chen, W.T.2
  • 45
    • 0026457798 scopus 로고
    • Tyrosine phosphorylation of membrane proteins mediates cellular invasion by transformed cells
    • Mueller, S. C., Yeh, Y. and Chen, W. T. (1992). Tyrosine phosphorylation of membrane proteins mediates cellular invasion by transformed cells. J. Cell Biol. 119, 1309-1325.
    • (1992) J. Cell Biol , vol.119 , pp. 1309-1325
    • Mueller, S.C.1    Yeh, Y.2    Chen, W.T.3
  • 46
    • 0030791315 scopus 로고    scopus 로고
    • Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion
    • Nakahara, H., Howard, L., Thompson, E. W., Sato, H., Seiki, M., Yeh, Y. and Chen, W. T. (1997). Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion. Proc. Natl. Acad. Sci. USA 94, 7959-7964.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 7959-7964
    • Nakahara, H.1    Howard, L.2    Thompson, E.W.3    Sato, H.4    Seiki, M.5    Yeh, Y.6    Chen, W.T.7
  • 47
    • 0035921432 scopus 로고    scopus 로고
    • Abp1p and cortactin, new "hand-holds" for actin
    • Olazabal, I. M. and Machesky, L. M. (2001). Abp1p and cortactin, new "hand-holds" for actin. J. Cell Biol. 154, 679-682.
    • (2001) J. Cell Biol , vol.154 , pp. 679-682
    • Olazabal, I.M.1    Machesky, L.M.2
  • 48
    • 0032566062 scopus 로고    scopus 로고
    • Overexpression of EMS1/cortactin in NIH3T3 fibroblasts causes increased cell motility and invasion in vitro
    • Patel, A. S., Schechter, G. L., Wasilenko, W. J. and Somers, K. D. (1998). Overexpression of EMS1/cortactin in NIH3T3 fibroblasts causes increased cell motility and invasion in vitro. Oncogene 16, 3227-3232.
    • (1998) Oncogene , vol.16 , pp. 3227-3232
    • Patel, A.S.1    Schechter, G.L.2    Wasilenko, W.J.3    Somers, K.D.4
  • 49
    • 0037452054 scopus 로고    scopus 로고
    • The cytoskeleton, cellular motility and the reductionist agenda
    • Pollard, T. D. (2003). The cytoskeleton, cellular motility and the reductionist agenda. Nature 422, 741-745.
    • (2003) Nature , vol.422 , pp. 741-745
    • Pollard, T.D.1
  • 50
    • 0030839472 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibition as a novel anticancer strategy: A review with special focus on batimastat and marimastat
    • Rasmussen, H. S. and McCann, P. P. (1997). Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat. Pharmacol. Ther. 75, 69-75.
    • (1997) Pharmacol. Ther , vol.75 , pp. 69-75
    • Rasmussen, H.S.1    McCann, P.P.2
  • 51
    • 0036468381 scopus 로고    scopus 로고
    • Coupling actin dynamics and membrane dynamics during endocytosis
    • Schafer, D. A. (2002). Coupling actin dynamics and membrane dynamics during endocytosis. Curr. Opin. Cell Biol. 14, 76-81.
    • (2002) Curr. Opin. Cell Biol , vol.14 , pp. 76-81
    • Schafer, D.A.1
  • 52
    • 0034329741 scopus 로고    scopus 로고
    • Actin assembly at membranes controlled by ARF6
    • Schafer, D. A., D'Souza-Schorey, C. and Cooper, J. A. (2000). Actin assembly at membranes controlled by ARF6. Traffic 1, 892-903.
    • (2000) Traffic , vol.1 , pp. 892-903
    • Schafer, D.A.1    D'Souza-Schorey, C.2    Cooper, J.A.3
  • 54
    • 0041423391 scopus 로고    scopus 로고
    • Combined array comparative genomic hybridization and tissue microarray analysis suggest PAK1 at 11q13.5-q14 as a critical oncogene target in ovarian carcinoma
    • Schrand, P., Schwerdtfeger, G., Burkhalter, F., Raggi, A., Schmidt, D., Ruffalo, T., King, W., Wilber, K., Mihatsch, M. J. and Moch, H. (2003). Combined array comparative genomic hybridization and tissue microarray analysis suggest PAK1 at 11q13.5-q14 as a critical oncogene target in ovarian carcinoma. Am. J. Pathol. 163, 985-992.
    • (2003) Am. J. Pathol , vol.163 , pp. 985-992
    • Schrand, P.1    Schwerdtfeger, G.2    Burkhalter, F.3    Raggi, A.4    Schmidt, D.5    Ruffalo, T.6    King, W.7    Wilber, K.8    Mihatsch, M.J.9    Moch, H.10
  • 55
    • 0029043876 scopus 로고
    • The involvement of the chromosome 11q13 region in human malignancies: Cyclin D1 and EMS1 are two new candidate oncogenes - a review
    • Schuuring, E. (1995). The involvement of the chromosome 11q13 region in human malignancies: cyclin D1 and EMS1 are two new candidate oncogenes - a review. Gene 159, 83-96.
    • (1995) Gene , vol.159 , pp. 83-96
    • Schuuring, E.1
  • 56
    • 3042798296 scopus 로고    scopus 로고
    • ADP-ribosylation factor 6 regulates tumor cell invasion through the activation of the MEK/ERK signaling pathway
    • Tague, S. E., Muralidharan, V. and D'Souza-Schorey, C. (2004). ADP-ribosylation factor 6 regulates tumor cell invasion through the activation of the MEK/ERK signaling pathway. Proc. Natl. Acad. Sci. USA 101, 9671-9676.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 9671-9676
    • Tague, S.E.1    Muralidharan, V.2    D'Souza-Schorey, C.3
  • 59
    • 0037114750 scopus 로고    scopus 로고
    • Cdc42/Rac1-dependent activation of the p21-activated kinase (PAK) regulates human platelet lamellipodia spreading: Implication of the cortical-actin binding protein cortactin
    • Vidal, C., Geny, B., Melle, J., Jandrot-Perrus, M. and Fontenay-Roupie, M. (2002). Cdc42/Rac1-dependent activation of the p21-activated kinase (PAK) regulates human platelet lamellipodia spreading: implication of the cortical-actin binding protein cortactin. Blood 100, 4462-4469.
    • (2002) Blood , vol.100 , pp. 4462-4469
    • Vidal, C.1    Geny, B.2    Melle, J.3    Jandrot-Perrus, M.4    Fontenay-Roupie, M.5
  • 60
    • 0028981376 scopus 로고
    • Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix
    • Vuori, K. and Ruoslahti, E. (1995). Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix. J. Biol. Chem. 270, 22259-22262.
    • (1995) J. Biol. Chem , vol.270 , pp. 22259-22262
    • Vuori, K.1    Ruoslahti, E.2
  • 65
    • 33947140891 scopus 로고    scopus 로고
    • Dissecting the functional domain requirements of cortactin in invadopodia formation
    • Webb, B. A., Jia, L., Eves, R. and Mak, A. S. (2007). Dissecting the functional domain requirements of cortactin in invadopodia formation. Eur. J. Cell Biol. 86, 189-206.
    • (2007) Eur. J. Cell Biol , vol.86 , pp. 189-206
    • Webb, B.A.1    Jia, L.2    Eves, R.3    Mak, A.S.4
  • 66
    • 0035475450 scopus 로고    scopus 로고
    • Cortactin: Coupling membrane dynamics to cortical actin assembly
    • Weed, S. A. and Parsons, J. T. (2001). Cortactin: coupling membrane dynamics to cortical actin assembly. Oncogene 20, 6418-6434.
    • (2001) Oncogene , vol.20 , pp. 6418-6434
    • Weed, S.A.1    Parsons, J.T.2
  • 67
    • 0034597092 scopus 로고    scopus 로고
    • Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex
    • Weed, S. A., Karginov, A. V., Schafer, D. A., Weaver, A. M., Kinley, A. W., Cooper, J. A. and Parsons, J. T. (2000). Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex. J. Cell Biol. 151, 29-40.
    • (2000) J. Cell Biol , vol.151 , pp. 29-40
    • Weed, S.A.1    Karginov, A.V.2    Schafer, D.A.3    Weaver, A.M.4    Kinley, A.W.5    Cooper, J.A.6    Parsons, J.T.7
  • 68
    • 0027419589 scopus 로고
    • Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex
    • Wu, H. and Parsons, J. T. (1993). Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex. J. Cell Biol. 120, 1417-1426.
    • (1993) J. Cell Biol , vol.120 , pp. 1417-1426
    • Wu, H.1    Parsons, J.T.2
  • 69
    • 0025940103 scopus 로고
    • Identification and characterization of a novel cytoskeleton-associated pp60src substrate
    • Wu, H., Reynolds, A. B., Kanner, S. B., Vines, R. R. and Parsons, J. T. (1991). Identification and characterization of a novel cytoskeleton-associated pp60src substrate. Mol. Cell. Biol. 11, 5113-5124.
    • (1991) Mol. Cell. Biol , vol.11 , pp. 5113-5124
    • Wu, H.1    Reynolds, A.B.2    Kanner, S.B.3    Vines, R.R.4    Parsons, J.T.5
  • 71
    • 0027423238 scopus 로고
    • Murine cortactin is phosphorylated in response to fibroblast growth factor-1 on tyrosine residues late in the G1 phase of the BALB/c 3T3 cell cycle
    • Zhan, X., Hu, X., Hampton, B., Burgess, W. H., Friesel, R. and Maciag, T. (1993). Murine cortactin is phosphorylated in response to fibroblast growth factor-1 on tyrosine residues late in the G1 phase of the BALB/c 3T3 cell cycle. J. Biol. Chem. 268, 24427-24431.
    • (1993) J. Biol. Chem , vol.268 , pp. 24427-24431
    • Zhan, X.1    Hu, X.2    Hampton, B.3    Burgess, W.H.4    Friesel, R.5    Maciag, T.6
  • 72
    • 14844293207 scopus 로고    scopus 로고
    • PAK and other Rho-associated kinases - effectors with surprisingly diverse mechanisms of regulation
    • Zhao, Z. S. and Manser, E. (2005). PAK and other Rho-associated kinases - effectors with surprisingly diverse mechanisms of regulation. Biochem. J. 386, 201-214.
    • (2005) Biochem. J , vol.386 , pp. 201-214
    • Zhao, Z.S.1    Manser, E.2
  • 73
    • 0031948850 scopus 로고    scopus 로고
    • A conserved negative regulatory region in alphaPAK: Inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1
    • Zhao, Z. S., Manser, E., Chen, X. Q., Chong, C., Leung, T. and Lim, L. (1998). A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1. Mol. Cell. Biol. 18, 2153-2163.
    • (1998) Mol. Cell. Biol , vol.18 , pp. 2153-2163
    • Zhao, Z.S.1    Manser, E.2    Chen, X.Q.3    Chong, C.4    Leung, T.5    Lim, L.6
  • 74
    • 34447530247 scopus 로고    scopus 로고
    • Receptor-mediated endocytosis involves tyrosine phosphorylation of cortactin
    • Zhu, J., Yu, D., Zeng, X. C., Zhou, K. and Zhan, X. (2007). Receptor-mediated endocytosis involves tyrosine phosphorylation of cortactin. J. Biol. Chem. 282, 16086-16094.
    • (2007) J. Biol. Chem , vol.282 , pp. 16086-16094
    • Zhu, J.1    Yu, D.2    Zeng, X.C.3    Zhou, K.4    Zhan, X.5


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