메뉴 건너뛰기




Volumn 34, Issue 2, 2013, Pages 526-541

Approaches to synthetic platelet analogs

Author keywords

Adhesion; Aggregation; Margination; Synthetic platelet

Indexed keywords

MARGINATION; MYELOSUPPRESSION; OPTIMUM DESIGNS; PATHOGEN REDUCTION; PHYSICOMECHANICAL PROPERTIES; PLATELET CONCENTRATES; PLATELET MEMBRANES; PLATELET TRANSFUSIONS; SHELF LIFE; SIDE EFFECT; SINGLE PARTICLE; SYNTHETIC ANALOGS;

EID: 84868204706     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.09.074     Document Type: Review
Times cited : (99)

References (135)
  • 1
    • 77949544484 scopus 로고    scopus 로고
    • Current concepts in platelet transfusion
    • Mohanty D. Current concepts in platelet transfusion. Asian J Transfus Sci 2009, 3(1):18-21.
    • (2009) Asian J Transfus Sci , vol.3 , Issue.1 , pp. 18-21
    • Mohanty, D.1
  • 2
    • 0034790918 scopus 로고    scopus 로고
    • Novel treatment modalities: new platelet preparations and substitutes
    • Lee D., Blajchman M.A. Novel treatment modalities: new platelet preparations and substitutes. Br J Haematol 2001, 114(3):496-505.
    • (2001) Br J Haematol , vol.114 , Issue.3 , pp. 496-505
    • Lee, D.1    Blajchman, M.A.2
  • 4
    • 84876795714 scopus 로고    scopus 로고
    • Available from: URL:
    • American red cross blood facts and statistics 2012 Sept, Available from: URL:. http://www.redcrossblood.org/learn-about-blood/blood-facts-and-statistics.
    • (2012) American red cross blood facts and statistics
  • 5
    • 80054996933 scopus 로고    scopus 로고
    • The National blood collection and utilization survey report
    • Sept. Available from: URL:
    • The National blood collection and utilization survey report. 2012 Sept. Available from: URL: http://www.aabb.org/programs/biovigilance/nbcus/Pages/default.aspx.
    • (2012)
  • 6
    • 47349090837 scopus 로고    scopus 로고
    • Pathogen reduction of blood components
    • Solheim B.G. Pathogen reduction of blood components. Transfus Apher Sci 2008, 39(1):75-82.
    • (2008) Transfus Apher Sci , vol.39 , Issue.1 , pp. 75-82
    • Solheim, B.G.1
  • 7
    • 33751512729 scopus 로고    scopus 로고
    • Pathogen-reduction systems for blood components: the current position and future trends
    • Seghatchian J., de Sousa G. Pathogen-reduction systems for blood components: the current position and future trends. Transfus Apher Sci 2006, 35(3):189-196.
    • (2006) Transfus Apher Sci , vol.35 , Issue.3 , pp. 189-196
    • Seghatchian, J.1    de Sousa, G.2
  • 8
    • 0142040273 scopus 로고    scopus 로고
    • FDA approach to evaluation of pathogen reduction technology
    • Epstein J.S., Vostal J.G. FDA approach to evaluation of pathogen reduction technology. Transfusion 2003, 43:1347-1350.
    • (2003) Transfusion , vol.43 , pp. 1347-1350
    • Epstein, J.S.1    Vostal, J.G.2
  • 9
    • 79954618951 scopus 로고    scopus 로고
    • Impact of pathogen reduction technology and storage in platelet additive solutions on platelet function
    • Galan A.M., Lozano M., Molina P., Navalon F., Marschner S., Goodrich R., et al. Impact of pathogen reduction technology and storage in platelet additive solutions on platelet function. Transfusion 2011, 51(4):808-815.
    • (2011) Transfusion , vol.51 , Issue.4 , pp. 808-815
    • Galan, A.M.1    Lozano, M.2    Molina, P.3    Navalon, F.4    Marschner, S.5    Goodrich, R.6
  • 10
    • 70349536147 scopus 로고    scopus 로고
    • ®) treated single-donor platelets resuspended in a mixture of autologous plasma and PAS
    • ®) treated single-donor platelets resuspended in a mixture of autologous plasma and PAS. Vox Sang 2009, 97(3):234-239.
    • (2009) Vox Sang , vol.97 , Issue.3 , pp. 234-239
    • Janetzko, K.1    Hinz, K.2    Marschner, S.3    Goodrich, R.4    Klüter, H.5
  • 11
    • 0031785013 scopus 로고    scopus 로고
    • Platelet refractoriness and alloimmunization
    • Slichter S.J. Platelet refractoriness and alloimmunization. Leukemia 1998, 12(Suppl. 1):S51-S53.
    • (1998) Leukemia , vol.12 , Issue.SUPPL. 1
    • Slichter, S.J.1
  • 12
    • 0033005204 scopus 로고    scopus 로고
    • The reduction of HLA class I expression on platelets: a potential approach in the management of HLA-alloimmunized refractory patients
    • Novotný V.M., Doxiadis, Brand A. The reduction of HLA class I expression on platelets: a potential approach in the management of HLA-alloimmunized refractory patients. Transfus Med Rev 1999, 13(2):95-105.
    • (1999) Transfus Med Rev , vol.13 , Issue.2 , pp. 95-105
    • Novotný, V.M.1    Doxiadis2    Brand, A.3
  • 13
    • 0031822071 scopus 로고    scopus 로고
    • Immunomodulatory effects of allogeneic blood transfusions: clinical manifestations and mechanisms
    • Blajchman M.A. Immunomodulatory effects of allogeneic blood transfusions: clinical manifestations and mechanisms. Vox Sang 1998, 74(Suppl. 2):315-319.
    • (1998) Vox Sang , vol.74 , Issue.SUPPL. 2 , pp. 315-319
    • Blajchman, M.A.1
  • 14
    • 0030817818 scopus 로고    scopus 로고
    • Transfusion-associated graft-versus-host disease
    • Orlin J.B., Ellis M.H. Transfusion-associated graft-versus-host disease. Curr Opin Hematol 1997, 4(6):442-448.
    • (1997) Curr Opin Hematol , vol.4 , Issue.6 , pp. 442-448
    • Orlin, J.B.1    Ellis, M.H.2
  • 15
    • 84868213938 scopus 로고    scopus 로고
    • Design and modification of nanoparticles for blood substitutes
    • Takeoka S. Design and modification of nanoparticles for blood substitutes. Organ Microcirc 2005, 13:35-41.
    • (2005) Organ Microcirc , vol.13 , pp. 35-41
    • Takeoka, S.1
  • 16
    • 79951500742 scopus 로고    scopus 로고
    • Alternatives to platelet transfusions in the management of platelet dysfunction or thrombocytopenia
    • Kickler T.S. Alternatives to platelet transfusions in the management of platelet dysfunction or thrombocytopenia. TransAltern Trans Med 2006, 8(2):127-134.
    • (2006) TransAltern Trans Med , vol.8 , Issue.2 , pp. 127-134
    • Kickler, T.S.1
  • 17
    • 38649111600 scopus 로고    scopus 로고
    • Artificial blood: an update on current red cell and platelet substitutes
    • Kresie L. Artificial blood: an update on current red cell and platelet substitutes. Proc (Bayl Univ Med Cent 2001, 14(2):158-161.
    • (2001) Proc (Bayl Univ Med Cent , vol.14 , Issue.2 , pp. 158-161
    • Kresie, L.1
  • 18
    • 0034923706 scopus 로고    scopus 로고
    • Novel platelet products, substitutes and alternatives
    • Blajchman M.A. Novel platelet products, substitutes and alternatives. Transfus Clin Biol 2001, 8(3):267-271.
    • (2001) Transfus Clin Biol , vol.8 , Issue.3 , pp. 267-271
    • Blajchman, M.A.1
  • 19
    • 0345661337 scopus 로고    scopus 로고
    • Platelets: structure, function, and their fundamental contribution to hemostasis and pathologic thrombosis
    • Springer, New York, R.C. Becker (Ed.)
    • Spencer F.A. Platelets: structure, function, and their fundamental contribution to hemostasis and pathologic thrombosis. Textbook of coronary thrombosis and thrombolysis: developments in cardiovascular medicine 1997, 31-49. Springer, New York. R.C. Becker (Ed.).
    • (1997) Textbook of coronary thrombosis and thrombolysis: developments in cardiovascular medicine , pp. 31-49
    • Spencer, F.A.1
  • 20
    • 0020008173 scopus 로고
    • Human platelet size, shape, and related functions in health and disease
    • Frojmovic M.M., Milton J.G. Human platelet size, shape, and related functions in health and disease. Physiol Rev 1982, 62(1):185-261.
    • (1982) Physiol Rev , vol.62 , Issue.1 , pp. 185-261
    • Frojmovic, M.M.1    Milton, J.G.2
  • 21
    • 0014709498 scopus 로고
    • The minimum energy of bending as a possible explanation of the bioconcave shape of the human red blood cell
    • Canham P. The minimum energy of bending as a possible explanation of the bioconcave shape of the human red blood cell. J Theor Biol 1970, 26:61-81.
    • (1970) J Theor Biol , vol.26 , pp. 61-81
    • Canham, P.1
  • 22
    • 43449112045 scopus 로고    scopus 로고
    • Micro-scale dynamic simulation of erythrocyte-platelet interaction in blood flow
    • AlMomani T., Udaykumar H.S., Marshall J.S., Chandran K.B. Micro-scale dynamic simulation of erythrocyte-platelet interaction in blood flow. Ann Biomed Eng 2008, 36(6):905-920.
    • (2008) Ann Biomed Eng , vol.36 , Issue.6 , pp. 905-920
    • AlMomani, T.1    Udaykumar, H.S.2    Marshall, J.S.3    Chandran, K.B.4
  • 23
    • 0032033099 scopus 로고    scopus 로고
    • Quantification of the passive mechanical properties of the resting platelet
    • Haga J.H., Beaudoina J., White J.G., Strony J. Quantification of the passive mechanical properties of the resting platelet. Ann Biomed Eng 1998, 26(2):268-277.
    • (1998) Ann Biomed Eng , vol.26 , Issue.2 , pp. 268-277
    • Haga, J.H.1    Beaudoina, J.2    White, J.G.3    Strony, J.4
  • 24
    • 32844466261 scopus 로고    scopus 로고
    • Stiffness of normal and pathological erythrocytes studied by means of atomic force microscopy
    • Dulińska I., Targosz M., Strojny W., Lekka M., Czuba P., Balwierz W., et al. Stiffness of normal and pathological erythrocytes studied by means of atomic force microscopy. J Biochem Biophys Methods 2006, 66(1-3):1-11.
    • (2006) J Biochem Biophys Methods , vol.66 , Issue.1-3 , pp. 1-11
    • Dulińska, I.1    Targosz, M.2    Strojny, W.3    Lekka, M.4    Czuba, P.5    Balwierz, W.6
  • 25
    • 0030053843 scopus 로고    scopus 로고
    • Measuring the viscoelastic properties of human platelets with the atomic force microscope
    • Radmacher M., Fritz M., Kacher C.M., Cleveland J.P., Hansma P.K. Measuring the viscoelastic properties of human platelets with the atomic force microscope. Biophys J 1996, 70(1):556-567.
    • (1996) Biophys J , vol.70 , Issue.1 , pp. 556-567
    • Radmacher, M.1    Fritz, M.2    Kacher, C.M.3    Cleveland, J.P.4    Hansma, P.K.5
  • 26
    • 0001142668 scopus 로고
    • Flow behavior of erythrocytes. II. Particle motions in concentrated suspensions of ghost cells
    • Goldsmith H. Flow behavior of erythrocytes. II. Particle motions in concentrated suspensions of ghost cells. J Colloid Interface Sci 1979, 71(2):383-407.
    • (1979) J Colloid Interface Sci , vol.71 , Issue.2 , pp. 383-407
    • Goldsmith, H.1
  • 27
    • 77954492820 scopus 로고    scopus 로고
    • Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery (review)
    • Huang R.B., Mocherla S., Heslinga M.J., Charoenphol P., Eniola-Adefeso O. Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery (review). Mol Membr Biol 2010, 27(4-6):190-205.
    • (2010) Mol Membr Biol , vol.27 , Issue.4-6 , pp. 190-205
    • Huang, R.B.1    Mocherla, S.2    Heslinga, M.J.3    Charoenphol, P.4    Eniola-Adefeso, O.5
  • 28
    • 0021723554 scopus 로고
    • Red blood cell deformability influences platelets-vessel wall interaction in flowing blood
    • Aarts P., Heethaar R., Sixma J. Red blood cell deformability influences platelets-vessel wall interaction in flowing blood. Blood 1984, 64(64):1228-1233.
    • (1984) Blood , vol.64 , Issue.64 , pp. 1228-1233
    • Aarts, P.1    Heethaar, R.2    Sixma, J.3
  • 29
    • 0022542613 scopus 로고
    • Micropipette aspiration of human platelets after exposure to aggregating agents
    • Burris S.M., Smith C.M., Tukey D.T., Clawson C.C., White J.G. Micropipette aspiration of human platelets after exposure to aggregating agents. Arteriosclerosis 1986, 6(3):321-325.
    • (1986) Arteriosclerosis , vol.6 , Issue.3 , pp. 321-325
    • Burris, S.M.1    Smith, C.M.2    Tukey, D.T.3    Clawson, C.C.4    White, J.G.5
  • 30
    • 0036161958 scopus 로고    scopus 로고
    • Platelet shape changes and adhesion under high shear flow
    • Kuwahara M. Platelet shape changes and adhesion under high shear flow. Arteriosclerosis 2002, 22(2):329-334.
    • (2002) Arteriosclerosis , vol.22 , Issue.2 , pp. 329-334
    • Kuwahara, M.1
  • 32
    • 34250818668 scopus 로고    scopus 로고
    • Adhesion mechanisms in platelet function
    • Ruggeri Z.M., Mendolicchio G.L. Adhesion mechanisms in platelet function. Circ Res 2007, 100(12):1673-1685.
    • (2007) Circ Res , vol.100 , Issue.12 , pp. 1673-1685
    • Ruggeri, Z.M.1    Mendolicchio, G.L.2
  • 34
    • 0038494921 scopus 로고    scopus 로고
    • Platelet-collagen interaction: is GPVI the central receptor?
    • Nieswandt B., Watson S.P. Platelet-collagen interaction: is GPVI the central receptor?. Blood 2003, 102(2):449-461.
    • (2003) Blood , vol.102 , Issue.2 , pp. 449-461
    • Nieswandt, B.1    Watson, S.P.2
  • 35
    • 0025216612 scopus 로고
    • The ligand binding site of the platelet integrin receptor GPIIb-IIIa is proximal to the second calcium binding domain of its alpha subunit
    • D'Souza S.E., Ginsberg M.H., Burke T., Plow E.F. The ligand binding site of the platelet integrin receptor GPIIb-IIIa is proximal to the second calcium binding domain of its alpha subunit. J Biol Chem 1990, 265(6):3440-3446.
    • (1990) J Biol Chem , vol.265 , Issue.6 , pp. 3440-3446
    • D'Souza, S.E.1    Ginsberg, M.H.2    Burke, T.3    Plow, E.F.4
  • 36
    • 0035984323 scopus 로고    scopus 로고
    • Rolling properties of rGPIbalpha-conjugated phospholipid vesicles with different membrane flexibilities on vWf surface under flow conditions
    • Takeoka S., Teramura Y., Okamura Y., Tsuchida E., Handa M., Ikeda Y. Rolling properties of rGPIbalpha-conjugated phospholipid vesicles with different membrane flexibilities on vWf surface under flow conditions. Biochem Biophys Res Commun 2002, 296(3):765-770.
    • (2002) Biochem Biophys Res Commun , vol.296 , Issue.3 , pp. 765-770
    • Takeoka, S.1    Teramura, Y.2    Okamura, Y.3    Tsuchida, E.4    Handa, M.5    Ikeda, Y.6
  • 38
    • 34250688226 scopus 로고    scopus 로고
    • Prolonged hemostatic ability of polyethylene glycol-modified polymerized albumin particles carrying fibrinogen gamma-chain dodecapeptide
    • Okamura Y., Fujie T., Maruyama H., Handa M., Ikeda Y., Takeoka S. Prolonged hemostatic ability of polyethylene glycol-modified polymerized albumin particles carrying fibrinogen gamma-chain dodecapeptide. Transfusion 2007, 47(7):1254-1262.
    • (2007) Transfusion , vol.47 , Issue.7 , pp. 1254-1262
    • Okamura, Y.1    Fujie, T.2    Maruyama, H.3    Handa, M.4    Ikeda, Y.5    Takeoka, S.6
  • 39
    • 0036660413 scopus 로고    scopus 로고
    • Reconstitution of adhesive properties of human platelets in liposomes carrying both recombinant glycoproteins Ia/IIa and Ib alpha under flow conditions: specific synergy of receptor-ligand interactions
    • Nishiya T., Kainoh M., Murata M., Handa M., Ikeda Y. Reconstitution of adhesive properties of human platelets in liposomes carrying both recombinant glycoproteins Ia/IIa and Ib alpha under flow conditions: specific synergy of receptor-ligand interactions. Blood 2002, 100(1):136-142.
    • (2002) Blood , vol.100 , Issue.1 , pp. 136-142
    • Nishiya, T.1    Kainoh, M.2    Murata, M.3    Handa, M.4    Ikeda, Y.5
  • 40
    • 78651552085 scopus 로고    scopus 로고
    • Deformability and adhesive force of artificial platelets measured by atomic force microscopy
    • Wada T., Okamura Y., Takeoka S., Sudo R., Ikeda Y., Tanishita K. Deformability and adhesive force of artificial platelets measured by atomic force microscopy. J Biorheol 2009, 23:35-40.
    • (2009) J Biorheol , vol.23 , pp. 35-40
    • Wada, T.1    Okamura, Y.2    Takeoka, S.3    Sudo, R.4    Ikeda, Y.5    Tanishita, K.6
  • 41
    • 0035674674 scopus 로고    scopus 로고
    • Platelet interactions with liposomes carrying recombinant platelet membrane glycoproteins or fibrinogen: approach to platelet substitutes
    • Nishiya T., Kainoh M., Murata M., Handa M., Ikeda Y. Platelet interactions with liposomes carrying recombinant platelet membrane glycoproteins or fibrinogen: approach to platelet substitutes. Artif Cells Blood Substit Immobil Biotechnol 2001, 29(6):453-464.
    • (2001) Artif Cells Blood Substit Immobil Biotechnol , vol.29 , Issue.6 , pp. 453-464
    • Nishiya, T.1    Kainoh, M.2    Murata, M.3    Handa, M.4    Ikeda, Y.5
  • 42
    • 84862663588 scopus 로고    scopus 로고
    • Mimicking adhesive functionalities of blood platelets using ligand-decorated liposomes
    • Epub Jun 5
    • Ravikumar M., Modery C.L., Wong T.L., Sen Gupta A. Mimicking adhesive functionalities of blood platelets using ligand-decorated liposomes. Bioconjug Chem 2012, Epub Jun 5.
    • (2012) Bioconjug Chem
    • Ravikumar, M.1    Modery, C.L.2    Wong, T.L.3    Sen Gupta, A.4
  • 43
    • 34547523962 scopus 로고    scopus 로고
    • Relationship between the binding sites for von Willebrand factor, phospholipid, and human factor VIII C2 inhibitor alloantibodies within the factor VIII C2 domain
    • Nogami K., Shima M., Giddings J.C., Takeyama M., Tanaka I., Yoshioka A. Relationship between the binding sites for von Willebrand factor, phospholipid, and human factor VIII C2 inhibitor alloantibodies within the factor VIII C2 domain. Int J Hematol 2007, 85(4):317-322.
    • (2007) Int J Hematol , vol.85 , Issue.4 , pp. 317-322
    • Nogami, K.1    Shima, M.2    Giddings, J.C.3    Takeyama, M.4    Tanaka, I.5    Yoshioka, A.6
  • 44
    • 0028227278 scopus 로고
    • Promotion of human platelet adhesion and aggregation by a synthetic, triple-helical "mini-collagen"
    • Rao G.H., Fields C.G., White J.G., Fields G.B. Promotion of human platelet adhesion and aggregation by a synthetic, triple-helical "mini-collagen". J Biol Chem 1994, 269(19):13899-13903.
    • (1994) J Biol Chem , vol.269 , Issue.19 , pp. 13899-13903
    • Rao, G.H.1    Fields, C.G.2    White, J.G.3    Fields, G.B.4
  • 45
    • 34547218894 scopus 로고    scopus 로고
    • Nanoparticles that display short collagen-related peptides. Potent stimulation of human platelet aggregation by triple helical motifs
    • Cejas M.A., Chen C., Kinney W.A., Maryanoff B.E. Nanoparticles that display short collagen-related peptides. Potent stimulation of human platelet aggregation by triple helical motifs. Bioconjug Chem 2007, 18(4):1025-1027.
    • (2007) Bioconjug Chem , vol.18 , Issue.4 , pp. 1025-1027
    • Cejas, M.A.1    Chen, C.2    Kinney, W.A.3    Maryanoff, B.E.4
  • 46
    • 47249117473 scopus 로고    scopus 로고
    • Thrombogenic collagen-mimetic peptides: self-assembly of triple helix-based fibrils driven by hydrophobic interactions
    • Cejas M.A., Kinney W.A., Chen C., Vinter J.G., Almond H.R., Balss K.M., et al. Thrombogenic collagen-mimetic peptides: self-assembly of triple helix-based fibrils driven by hydrophobic interactions. Proc Natl Acad Sci USA 2008, 105(25):8513-8518.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.25 , pp. 8513-8518
    • Cejas, M.A.1    Kinney, W.A.2    Chen, C.3    Vinter, J.G.4    Almond, H.R.5    Balss, K.M.6
  • 47
    • 0026533067 scopus 로고
    • Erythrocytes with covalently bound fibrinogen as a cellular replacement for the treatment of thrombocytopenia
    • Agam G., Livne A.A. Erythrocytes with covalently bound fibrinogen as a cellular replacement for the treatment of thrombocytopenia. Eur J Clin Invest 1992, 22:105-112.
    • (1992) Eur J Clin Invest , vol.22 , pp. 105-112
    • Agam, G.1    Livne, A.A.2
  • 48
    • 0026594781 scopus 로고
    • Thromboerythrocytes. In vitro studies of a potential autologous, semi-artificial alternative to platelet transfusions
    • Coller B.S., Springer K.T., Beer J.H., Mohandas N., Scudder L.E., Norton K.J., et al. Thromboerythrocytes. In vitro studies of a potential autologous, semi-artificial alternative to platelet transfusions. J Clin Invest 1992, 89(2):546-555.
    • (1992) J Clin Invest , vol.89 , Issue.2 , pp. 546-555
    • Coller, B.S.1    Springer, K.T.2    Beer, J.H.3    Mohandas, N.4    Scudder, L.E.5    Norton, K.J.6
  • 49
    • 77953332949 scopus 로고    scopus 로고
    • Current and future cellular transfusion products
    • Gelderman M.P., Vostal J.G. Current and future cellular transfusion products. Clin Lab Med 2010, 30(2):443-452.
    • (2010) Clin Lab Med , vol.30 , Issue.2 , pp. 443-452
    • Gelderman, M.P.1    Vostal, J.G.2
  • 50
    • 84876802207 scopus 로고    scopus 로고
    • ProFibrix fibrocaps
    • Sept. Available from: URL:
    • ProFibrix fibrocaps. 2012 Sept. Available from: URL: http://www.aabb.org/programs/biovigilance/nbcus/Pages/default.aspx.
    • (2012)
  • 51
    • 17444405937 scopus 로고    scopus 로고
    • Fibrinogen-coated albumin microcapsules reduce bleeding in severely thrombocytopenic rabbits
    • Levi M., Friederich P.W., Middleton S., de Groot P.G., Wu Y.P., Harris R., et al. Fibrinogen-coated albumin microcapsules reduce bleeding in severely thrombocytopenic rabbits. Nat Med 1999, 5(1):107-111.
    • (1999) Nat Med , vol.5 , Issue.1 , pp. 107-111
    • Levi, M.1    Friederich, P.W.2    Middleton, S.3    de Groot, P.G.4    Wu, Y.P.5    Harris, R.6
  • 52
    • 0000242193 scopus 로고
    • A new hemostatic agent: thrombospheres shorten the bleeding time (BT) in thrombocytopenic rabbits
    • Yen R.C., Ho T.W., Blajchman M.A. A new hemostatic agent: thrombospheres shorten the bleeding time (BT) in thrombocytopenic rabbits. Thromb Haemost 1995, 73:986.
    • (1995) Thromb Haemost , vol.73 , pp. 986
    • Yen, R.C.1    Ho, T.W.2    Blajchman, M.A.3
  • 53
    • 0003121221 scopus 로고
    • A novel approach to correcting the bleeding associated with thrombocytopenia
    • Yen R.C.K., Ho T.W.C. A novel approach to correcting the bleeding associated with thrombocytopenia. Transfusion 1995, 35:41S.
    • (1995) Transfusion , vol.35
    • Yen, R.C.K.1    Ho, T.W.C.2
  • 54
    • 84876794827 scopus 로고    scopus 로고
    • Available from: URL:
    • Advanced therapeutics fibrinoplate 2012 Sept, Available from: URL:. http://www.advtx.com/Fibrinoplate-s-details.htm.
    • (2012) Advanced therapeutics fibrinoplate
  • 56
    • 0041559949 scopus 로고    scopus 로고
    • RGD modified polymers: biomaterials for stimulated cell adhesion and beyond
    • Hersel U., Dahmen C., Kessler H. RGD modified polymers: biomaterials for stimulated cell adhesion and beyond. Biomaterials 2003, 24(24):4385-4415.
    • (2003) Biomaterials , vol.24 , Issue.24 , pp. 4385-4415
    • Hersel, U.1    Dahmen, C.2    Kessler, H.3
  • 57
    • 59849127731 scopus 로고    scopus 로고
    • Development of fibrinogen gamma-chain peptide-coated, adenosine diphosphate-encapsulated liposomes as a synthetic platelet substitute
    • Okamura Y., Takeoka S., Eto K., Maekawa I., Fujie T., Maruyama H., et al. Development of fibrinogen gamma-chain peptide-coated, adenosine diphosphate-encapsulated liposomes as a synthetic platelet substitute. J Thromb Haemost 2009, 7(3):470-477.
    • (2009) J Thromb Haemost , vol.7 , Issue.3 , pp. 470-477
    • Okamura, Y.1    Takeoka, S.2    Eto, K.3    Maekawa, I.4    Fujie, T.5    Maruyama, H.6
  • 58
    • 21644475963 scopus 로고    scopus 로고
    • Hemostatic effects of fibrinogen gamma-chain dodecapeptide-conjugated polymerized albumin particles in vitro and in vivo
    • Okamura Y., Takeoka S., Teramura Y., Maruyama H., Tsuchida E., Handa M., et al. Hemostatic effects of fibrinogen gamma-chain dodecapeptide-conjugated polymerized albumin particles in vitro and in vivo. Transfusion 2005, 45(7):1221-1228.
    • (2005) Transfusion , vol.45 , Issue.7 , pp. 1221-1228
    • Okamura, Y.1    Takeoka, S.2    Teramura, Y.3    Maruyama, H.4    Tsuchida, E.5    Handa, M.6
  • 59
    • 45349083291 scopus 로고    scopus 로고
    • Haemostatic effects of polymerized albumin particles carrying fibrinogen gamma-chain dodecapeptide as platelet substitutes in severely thrombocytopenic rabbits
    • Okamura Y., Fujie T., Nogawa M., Maruyama H., Handa M., Ikeda Y., et al. Haemostatic effects of polymerized albumin particles carrying fibrinogen gamma-chain dodecapeptide as platelet substitutes in severely thrombocytopenic rabbits. Transfus Med 2008, 18(3):158-166.
    • (2008) Transfus Med , vol.18 , Issue.3 , pp. 158-166
    • Okamura, Y.1    Fujie, T.2    Nogawa, M.3    Maruyama, H.4    Handa, M.5    Ikeda, Y.6
  • 60
    • 27944467898 scopus 로고    scopus 로고
    • Hemostatic effects of phospholipid vesicles carrying fibrinogen gamma chain dodecapeptide in vitro and in vivo
    • Okamura Y., Maekawa I., Teramura Y., Maruyama H., Handa M., Ikeda Y., et al. Hemostatic effects of phospholipid vesicles carrying fibrinogen gamma chain dodecapeptide in vitro and in vivo. Bioconjug Chem 2005, 16(6):1589-1596.
    • (2005) Bioconjug Chem , vol.16 , Issue.6 , pp. 1589-1596
    • Okamura, Y.1    Maekawa, I.2    Teramura, Y.3    Maruyama, H.4    Handa, M.5    Ikeda, Y.6
  • 61
    • 0028049293 scopus 로고
    • Design and synthesis of novel cyclic RGD-containing peptides as highly potent and selective integrin alpha IIb beta 3 antagonists
    • Cheng S., Craig W.S., Mullen D., Tschopp J.F., Dixon D., Pierschbacher M.D. Design and synthesis of novel cyclic RGD-containing peptides as highly potent and selective integrin alpha IIb beta 3 antagonists. J Med Chem 1994, 37(1):1-8.
    • (1994) J Med Chem , vol.37 , Issue.1 , pp. 1-8
    • Cheng, S.1    Craig, W.S.2    Mullen, D.3    Tschopp, J.F.4    Dixon, D.5    Pierschbacher, M.D.6
  • 62
    • 0031780567 scopus 로고    scopus 로고
    • Atrial fibrillation after bypass surgery: does the arrhythmia or the characteristics of the patients prolong hospital stay?
    • Borzak S., Tisdale J.E., Amin N.B., Goldberg A.D., Frank D., Padhi I.D., et al. Atrial fibrillation after bypass surgery: does the arrhythmia or the characteristics of the patients prolong hospital stay?. Chest 1998, 113(6):1489-1491.
    • (1998) Chest , vol.113 , Issue.6 , pp. 1489-1491
    • Borzak, S.1    Tisdale, J.E.2    Amin, N.B.3    Goldberg, A.D.4    Frank, D.5    Padhi, I.D.6
  • 63
    • 84861135976 scopus 로고    scopus 로고
    • Peptide-decorated liposomes promote arrest and aggregation of activated platelets under flow on vascular injury relevant protein surfaces in vitro
    • Ravikumar M., Modery C.L., Wong T.L., Sen Gupta A. Peptide-decorated liposomes promote arrest and aggregation of activated platelets under flow on vascular injury relevant protein surfaces in vitro. Biomacromolecules 2012, 13(5):1495-1502.
    • (2012) Biomacromolecules , vol.13 , Issue.5 , pp. 1495-1502
    • Ravikumar, M.1    Modery, C.L.2    Wong, T.L.3    Sen Gupta, A.4
  • 64
    • 0036851876 scopus 로고    scopus 로고
    • Role of platelets in atherothrombosis
    • Ruggeri Z.M. Role of platelets in atherothrombosis. Nat Med 2002, 8(11):1227-1234.
    • (2002) Nat Med , vol.8 , Issue.11 , pp. 1227-1234
    • Ruggeri, Z.M.1
  • 65
    • 33645295529 scopus 로고    scopus 로고
    • Platelet interactions with vessel wall components during thrombogenesis
    • Ruggeri Z.M. Platelet interactions with vessel wall components during thrombogenesis. Blood Cells Mol Dis 2006, 36(2):145-147.
    • (2006) Blood Cells Mol Dis , vol.36 , Issue.2 , pp. 145-147
    • Ruggeri, Z.M.1
  • 66
    • 0033168347 scopus 로고    scopus 로고
    • Contribution of distinct adhesive interactions to platelet aggregation in flowing blood
    • Ruggeri Z.M., Dent J.A., Saldívar E. Contribution of distinct adhesive interactions to platelet aggregation in flowing blood. Blood 1999, 94(1):172-178.
    • (1999) Blood , vol.94 , Issue.1 , pp. 172-178
    • Ruggeri, Z.M.1    Dent, J.A.2    Saldívar, E.3
  • 67
    • 33847292309 scopus 로고
    • Effects of dried fraction from platelets on Ca clotting time of normal plasmas and plasma in thrombocytopenia and hemophilia
    • Klein E., Farber S., Freman G. Effects of dried fraction from platelets on Ca clotting time of normal plasmas and plasma in thrombocytopenia and hemophilia. Fed Proc 1955, 14:410-1324.
    • (1955) Fed Proc , vol.14 , pp. 410-1324
    • Klein, E.1    Farber, S.2    Freman, G.3
  • 68
    • 0000041193 scopus 로고
    • The preparation and clinical administration of lyophilized platelet material to children with acute leukemia and aplastic anemia
    • Arnold P., Djerassi I., Ferber S., Freeman G., Klein E., Toch R. The preparation and clinical administration of lyophilized platelet material to children with acute leukemia and aplastic anemia. J Pediatr 1956, 49(5):517-522.
    • (1956) J Pediatr , vol.49 , Issue.5 , pp. 517-522
    • Arnold, P.1    Djerassi, I.2    Ferber, S.3    Freeman, G.4    Klein, E.5    Toch, R.6
  • 69
    • 33847300433 scopus 로고
    • Hemostasis following the administration of lyophilized platelet material in secondary thrombocytopenia
    • Klein E., Farber S., Djorassi I., Arnold P. Hemostasis following the administration of lyophilized platelet material in secondary thrombocytopenia. Sixth Intl Congr Hematol 1956, 525.
    • (1956) Sixth Intl Congr Hematol , pp. 525
    • Klein, E.1    Farber, S.2    Djorassi, I.3    Arnold, P.4
  • 70
    • 0001493869 scopus 로고
    • Comparing effectiveness of fresh and lyophilized platelets in controlling irradiation hemorrhage in the rat
    • Fliedner D., Sorensen D., Bond V., Fliedner T. Comparing effectiveness of fresh and lyophilized platelets in controlling irradiation hemorrhage in the rat. Proc Soc Expl Biol 1958, 99:731-733.
    • (1958) Proc Soc Expl Biol , vol.99 , pp. 731-733
    • Fliedner, D.1    Sorensen, D.2    Bond, V.3    Fliedner, T.4
  • 71
    • 84912334933 scopus 로고
    • Effectiveness of transfusions of fresh and lyophilized platelets in controlling bleeding due to thrombocytopenia
    • Jackson D., Sorensen D., Cronkite E., Bond V., Fliedner T. Effectiveness of transfusions of fresh and lyophilized platelets in controlling bleeding due to thrombocytopenia. J Clin Invest 1959, 38:1689-1697.
    • (1959) J Clin Invest , vol.38 , pp. 1689-1697
    • Jackson, D.1    Sorensen, D.2    Cronkite, E.3    Bond, V.4    Fliedner, T.5
  • 72
    • 0015531096 scopus 로고
    • An application of lyophilization and scanning electron microscopy
    • Murphy M. An application of lyophilization and scanning electron microscopy. Thrombos Diath Haemorrh 1972, 28:237-243.
    • (1972) Thrombos Diath Haemorrh , vol.28 , pp. 237-243
    • Murphy, M.1
  • 73
    • 0016689054 scopus 로고
    • Platelets fixed with paraformaldehyde: a new reagent for assay of von Willebrand Factor and platelet aggregating factor
    • Allain J., Cooper H., Wagner R., Brinkhous K. Platelets fixed with paraformaldehyde: a new reagent for assay of von Willebrand Factor and platelet aggregating factor. J Lab Clin Med 1975, 85:328-335.
    • (1975) J Lab Clin Med , vol.85 , pp. 328-335
    • Allain, J.1    Cooper, H.2    Wagner, R.3    Brinkhous, K.4
  • 74
    • 0018175866 scopus 로고
    • Preservation of platelet receptors for platelet aggregating factor/von Willebrand factor by air drying, freezing, or lyophilization: new stable platelet preparations for von Willebrand factor assays
    • Brinkhous K.M., Read M.S. Preservation of platelet receptors for platelet aggregating factor/von Willebrand factor by air drying, freezing, or lyophilization: new stable platelet preparations for von Willebrand factor assays. Thromb Res 1978, 13(4):591-597.
    • (1978) Thromb Res , vol.13 , Issue.4 , pp. 591-597
    • Brinkhous, K.M.1    Read, M.S.2
  • 75
    • 0028816030 scopus 로고
    • Preservation of hemostatic and structural properties of rehydrated lyophilized platelets: potential for long-term storage of dried platelets for transfusion
    • Read M.S., Reddick R.L., Bode A.P., Bellinger D.A., Nichols T.C., Taylor K., et al. Preservation of hemostatic and structural properties of rehydrated lyophilized platelets: potential for long-term storage of dried platelets for transfusion. Proc Natl Acad Sci USA 1995, 92(2):397-401.
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.2 , pp. 397-401
    • Read, M.S.1    Reddick, R.L.2    Bode, A.P.3    Bellinger, D.A.4    Nichols, T.C.5    Taylor, K.6
  • 77
    • 0007434036 scopus 로고    scopus 로고
    • Fibrinogen binding to rehydrated lyophilized platelet surface GPIIb-IIIa: normal clot formation and tPA lysis
    • Sanders W.E., Khandelwal G., Bellinger D.A., Bode A.P., Read M.S. Fibrinogen binding to rehydrated lyophilized platelet surface GPIIb-IIIa: normal clot formation and tPA lysis. Blood 1996, 88(Suppl. 1):30a.
    • (1996) Blood , vol.88 , Issue.SUPPL. 1
    • Sanders, W.E.1    Khandelwal, G.2    Bellinger, D.A.3    Bode, A.P.4    Read, M.S.5
  • 78
    • 0029073889 scopus 로고
    • Preclinical testing of lyophilized platelets as a product for transfusion medicine
    • Bode A.P. Preclinical testing of lyophilized platelets as a product for transfusion medicine. Transfus Sci 1995, 16(2):183-185.
    • (1995) Transfus Sci , vol.16 , Issue.2 , pp. 183-185
    • Bode, A.P.1
  • 79
    • 0030923256 scopus 로고    scopus 로고
    • The thrombocytopenic rabbit bleeding time model to evaluate the in vivo hemostatic efficacy of platelets and platelet substitutes
    • Blajchman M.A., Lee D.H. The thrombocytopenic rabbit bleeding time model to evaluate the in vivo hemostatic efficacy of platelets and platelet substitutes. Transfus Med Rev 1997, 11(2):95-105.
    • (1997) Transfus Med Rev , vol.11 , Issue.2 , pp. 95-105
    • Blajchman, M.A.1    Lee, D.H.2
  • 80
    • 0013562972 scopus 로고
    • Hemostatic properties of human lyophilized platelets in a thrombocytopenic rabbit model and a simulated bleeding time device
    • Bode A.P., Blajchman M.A., Bardossy L., Read M. Hemostatic properties of human lyophilized platelets in a thrombocytopenic rabbit model and a simulated bleeding time device. Blood 1994, 84(Suppl. 1):464a.
    • (1994) Blood , vol.84 , Issue.SUPPL. 1
    • Bode, A.P.1    Blajchman, M.A.2    Bardossy, L.3    Read, M.4
  • 81
    • 0025227931 scopus 로고
    • Bleeding complications associated with cardiopulmonary bypass
    • Woodman R.C., Harker L.A. Bleeding complications associated with cardiopulmonary bypass. Blood 1990, 76(9):1680-1697.
    • (1990) Blood , vol.76 , Issue.9 , pp. 1680-1697
    • Woodman, R.C.1    Harker, L.A.2
  • 82
    • 37549021531 scopus 로고    scopus 로고
    • Correction of the bleeding time with lyophilized platelet infusions in dogs on cardiopulmonary bypass
    • Bode A.P., Lust R.M., Read M.S., Fischer T.H. Correction of the bleeding time with lyophilized platelet infusions in dogs on cardiopulmonary bypass. Clin Appl Thromb Hemost 2008, 14(1):38-54.
    • (2008) Clin Appl Thromb Hemost , vol.14 , Issue.1 , pp. 38-54
    • Bode, A.P.1    Lust, R.M.2    Read, M.S.3    Fischer, T.H.4
  • 83
    • 0031449859 scopus 로고    scopus 로고
    • Lyophilized platelets: nearing clinical trials
    • Bode A.P., Read M., Summaria L., Lust R. Lyophilized platelets: nearing clinical trials. Platelets 1997, 8:436-437.
    • (1997) Platelets , vol.8 , pp. 436-437
    • Bode, A.P.1    Read, M.2    Summaria, L.3    Lust, R.4
  • 84
    • 0012098552 scopus 로고    scopus 로고
    • Lyophilized platelets for transfusion medicine
    • Elsevier, Amsterdam, J. Seghatchan, E.L. Snyder (Eds.)
    • Bode A.P., Read M. Lyophilized platelets for transfusion medicine. Platelet therapy: current status and future challenges 2000, 131-167. Elsevier, Amsterdam. J. Seghatchan, E.L. Snyder (Eds.).
    • (2000) Platelet therapy: current status and future challenges , pp. 131-167
    • Bode, A.P.1    Read, M.2
  • 87
    • 84855199917 scopus 로고    scopus 로고
    • Lyophilization of human platelet and study of its aggregability
    • Nasiri S., Khosroshahi B.N. Lyophilization of human platelet and study of its aggregability. Int J Drug Del 2011, 3:241-244.
    • (2011) Int J Drug Del , vol.3 , pp. 241-244
    • Nasiri, S.1    Khosroshahi, B.N.2
  • 89
    • 80054714406 scopus 로고    scopus 로고
    • Production and characterization of liquid-stored and lyophilized reconstituted human infusible platelet membranes
    • Ahmadzadeh N., Yari F., Amirizadeh N., Khorramizadeh M.R. Production and characterization of liquid-stored and lyophilized reconstituted human infusible platelet membranes. Int J Lab Hematol 2011, 33(6):586-592.
    • (2011) Int J Lab Hematol , vol.33 , Issue.6 , pp. 586-592
    • Ahmadzadeh, N.1    Yari, F.2    Amirizadeh, N.3    Khorramizadeh, M.R.4
  • 90
    • 0035227457 scopus 로고    scopus 로고
    • Infusible platelet membranes retain partial functionality of the platelet GPIb/IX/V receptor complex
    • Graham S.S., Gonchoroff N.J., Miller J.L. Infusible platelet membranes retain partial functionality of the platelet GPIb/IX/V receptor complex. Am J Clin Pathol 2001, 115(1):144-147.
    • (2001) Am J Clin Pathol , vol.115 , Issue.1 , pp. 144-147
    • Graham, S.S.1    Gonchoroff, N.J.2    Miller, J.L.3
  • 91
    • 0033823078 scopus 로고    scopus 로고
    • Infusible platelet membranes improve hemostasis in thrombocytopenic blood: experimental studies under flow conditions
    • Galan A.-M., Bozzo J., Pino M., Reverter J., Mazzara R., Ordinas A. Infusible platelet membranes improve hemostasis in thrombocytopenic blood: experimental studies under flow conditions. Transfusion 2000, 40:1074-1080.
    • (2000) Transfusion , vol.40 , pp. 1074-1080
    • Galan, A.-M.1    Bozzo, J.2    Pino, M.3    Reverter, J.4    Mazzara, R.5    Ordinas, A.6
  • 92
    • 0030851037 scopus 로고    scopus 로고
    • Frozen platelets and platelet substitutes in transfusion medicine
    • Alving B.M., Reid T.J., Fratantoni J.C., Finlayson J.S. Frozen platelets and platelet substitutes in transfusion medicine. Transfusion 1997, 37(8):866-876.
    • (1997) Transfusion , vol.37 , Issue.8 , pp. 866-876
    • Alving, B.M.1    Reid, T.J.2    Fratantoni, J.C.3    Finlayson, J.S.4
  • 93
    • 0027287933 scopus 로고
    • A liposome based platelet substitute, the plateletsome, with hemostatic efficacy
    • Rybak M.E., Renzulli L.A. A liposome based platelet substitute, the plateletsome, with hemostatic efficacy. Biomater Artif Cells Immobilization Biotechnol 1993, 21(2):101-118.
    • (1993) Biomater Artif Cells Immobilization Biotechnol , vol.21 , Issue.2 , pp. 101-118
    • Rybak, M.E.1    Renzulli, L.A.2
  • 94
    • 84937055139 scopus 로고
    • A platelet substitute-the plateletsome to be used in transfusion therapy
    • US Army Medical Research and Development Command, Fort Detrick, Frederick, Maryland, Contract No. DAMD17-87-C-7172
    • Rybak M.E. A platelet substitute-the plateletsome to be used in transfusion therapy. Report by university of massachusetts medical center 1989, 1-41. US Army Medical Research and Development Command, Fort Detrick, Frederick, Maryland, Contract No. DAMD17-87-C-7172.
    • (1989) Report by university of massachusetts medical center , pp. 1-41
    • Rybak, M.E.1
  • 95
    • 33845681193 scopus 로고    scopus 로고
    • New strategy of platelet substitutes for enhancing platelet aggregation at high shear rates: cooperative effects of a mixed system of fibrinogen gamma-chain dodecapeptide- or glycoprotein Ibalpha-conjugated latex beads under flow conditions
    • Okamura Y., Handa M., Suzuki H., Ikeda Y., Takeoka S. New strategy of platelet substitutes for enhancing platelet aggregation at high shear rates: cooperative effects of a mixed system of fibrinogen gamma-chain dodecapeptide- or glycoprotein Ibalpha-conjugated latex beads under flow conditions. J Artif Organs 2006, 9(4):251-258.
    • (2006) J Artif Organs , vol.9 , Issue.4 , pp. 251-258
    • Okamura, Y.1    Handa, M.2    Suzuki, H.3    Ikeda, Y.4    Takeoka, S.5
  • 96
    • 72149100143 scopus 로고    scopus 로고
    • Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers
    • Charoenphol P., Huang R.B., Eniola-Adefeso O. Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers. Biomaterials 2010, 31(6):1392-1402.
    • (2010) Biomaterials , vol.31 , Issue.6 , pp. 1392-1402
    • Charoenphol, P.1    Huang, R.B.2    Eniola-Adefeso, O.3
  • 97
    • 84868213422 scopus 로고    scopus 로고
    • Motion of artificial platelet in the model arteriole. Proceedings of summer bioengineering conference. Key Biscayne, Florida
    • Fujita H, Tsuji T, Tabata T, Takeoka S, Ikeda Y, Tanishita K. Motion of artificial platelet in the model arteriole. Proceedings of summer bioengineering conference. Key Biscayne, Florida. 2003: p. 29-30.
    • (2003) , pp. 29-30
    • Fujita, H.1    Tsuji, T.2    Tabata, T.3    Takeoka, S.4    Ikeda, Y.5    Tanishita, K.6
  • 98
    • 52649118065 scopus 로고    scopus 로고
    • The effect of shape on the margination dynamics of non-neutrally buoyant particles in two-dimensional shear flows
    • Gentile F., Chiappini C., Fine D., Bhavane R.C., Peluccio M.S., Cheng M.M.-C., et al. The effect of shape on the margination dynamics of non-neutrally buoyant particles in two-dimensional shear flows. J Biomech 2008, 41(10):2312-2318.
    • (2008) J Biomech , vol.41 , Issue.10 , pp. 2312-2318
    • Gentile, F.1    Chiappini, C.2    Fine, D.3    Bhavane, R.C.4    Peluccio, M.S.5    Cheng, M.M.-C.6
  • 99
    • 79951820750 scopus 로고    scopus 로고
    • The effects of particle size, density and shape on margination of nanoparticles in microcirculation
    • Toy R., Hayden E., Shoup C., Baskaran H., Karathanasis E. The effects of particle size, density and shape on margination of nanoparticles in microcirculation. Nanotechnology 2011, 22(11):1-9.
    • (2011) Nanotechnology , vol.22 , Issue.11 , pp. 1-9
    • Toy, R.1    Hayden, E.2    Shoup, C.3    Baskaran, H.4    Karathanasis, E.5
  • 100
    • 17144417434 scopus 로고    scopus 로고
    • A theoretical model for the margination of particles within blood vessels
    • Decuzzi P., Lee S., Bhushan B., Ferrari M. A theoretical model for the margination of particles within blood vessels. Ann Biomed Eng 2005, 33(2):179-190.
    • (2005) Ann Biomed Eng , vol.33 , Issue.2 , pp. 179-190
    • Decuzzi, P.1    Lee, S.2    Bhushan, B.3    Ferrari, M.4
  • 101
    • 78751508035 scopus 로고    scopus 로고
    • Shape-specific polymeric nanomedicine: emerging opportunities and challenges
    • Tao L., Hu W., Liu Y., Huang G., Sumer B.D., Gao J. Shape-specific polymeric nanomedicine: emerging opportunities and challenges. Exp Biol Med 2011, 236(1):20-29.
    • (2011) Exp Biol Med , vol.236 , Issue.1 , pp. 20-29
    • Tao, L.1    Hu, W.2    Liu, Y.3    Huang, G.4    Sumer, B.D.5    Gao, J.6
  • 102
    • 79960771888 scopus 로고    scopus 로고
    • Novel platforms for vascular carriers with controlled geometry
    • Pillai J.D., Dunn S.S., Napier M.E., DeSimone J.M. Novel platforms for vascular carriers with controlled geometry. IUBMB Life 2011, 63(8):596-606.
    • (2011) IUBMB Life , vol.63 , Issue.8 , pp. 596-606
    • Pillai, J.D.1    Dunn, S.S.2    Napier, M.E.3    DeSimone, J.M.4
  • 103
    • 77955413581 scopus 로고    scopus 로고
    • Flow and adhesion of drug carriers in blood vessels depend on their shape: a study using model synthetic microvascular networks
    • Doshi N., Prabhakarpandian B., Rea-Ramsey A., Pant K., Sundaram S., Mitragotri S. Flow and adhesion of drug carriers in blood vessels depend on their shape: a study using model synthetic microvascular networks. J Control Release 2010, 146(2):196-200.
    • (2010) J Control Release , vol.146 , Issue.2 , pp. 196-200
    • Doshi, N.1    Prabhakarpandian, B.2    Rea-Ramsey, A.3    Pant, K.4    Sundaram, S.5    Mitragotri, S.6
  • 104
    • 0014828510 scopus 로고
    • Observations on the change in shape of blood platelets brought about by adenosine diphosphate
    • Born G. Observations on the change in shape of blood platelets brought about by adenosine diphosphate. J Physiol 1970, 209:487-511.
    • (1970) J Physiol , vol.209 , pp. 487-511
    • Born, G.1
  • 105
    • 77953402341 scopus 로고    scopus 로고
    • Challenging nature's monopoly on the creation of well-defined nanoparticles
    • Jeong W., Napier M.E., DeSimone J.M. Challenging nature's monopoly on the creation of well-defined nanoparticles. Nanomedicine 2010, 5(4):633-639.
    • (2010) Nanomedicine , vol.5 , Issue.4 , pp. 633-639
    • Jeong, W.1    Napier, M.E.2    DeSimone, J.M.3
  • 106
    • 79952392869 scopus 로고    scopus 로고
    • Swelling behavior of nanoscale, shape- and size-specific, hydrogel particles fabricated using imprint lithography
    • Caldorera-Moore M., Kang M.K., Moore Z., Singh V., Sreenivasan S.V., Shi L., et al. Swelling behavior of nanoscale, shape- and size-specific, hydrogel particles fabricated using imprint lithography. Soft Matter 2011, 7(6):2879-2887.
    • (2011) Soft Matter , vol.7 , Issue.6 , pp. 2879-2887
    • Caldorera-Moore, M.1    Kang, M.K.2    Moore, Z.3    Singh, V.4    Sreenivasan, S.V.5    Shi, L.6
  • 107
    • 77949942627 scopus 로고    scopus 로고
    • Designer nanoparticles: incorporating size, shape and triggered release into nanoscale drug carriers
    • Caldorera-Moore M., Guimard N., Shi L., Roy K. Designer nanoparticles: incorporating size, shape and triggered release into nanoscale drug carriers. Expert Opin Drug Deliv 2010, 7(4):479-495.
    • (2010) Expert Opin Drug Deliv , vol.7 , Issue.4 , pp. 479-495
    • Caldorera-Moore, M.1    Guimard, N.2    Shi, L.3    Roy, K.4
  • 108
    • 57849113507 scopus 로고    scopus 로고
    • Physical approaches to biomaterial design
    • Mitragotri S., Lahann J. Physical approaches to biomaterial design. Nat Mater 2009, 8(1):15-23.
    • (2009) Nat Mater , vol.8 , Issue.1 , pp. 15-23
    • Mitragotri, S.1    Lahann, J.2
  • 109
    • 34547178393 scopus 로고    scopus 로고
    • Particle shape: a new design parameter for micro- and nanoscale drug delivery carriers
    • Champion J.A., Katare Y.K., Mitragotri S. Particle shape: a new design parameter for micro- and nanoscale drug delivery carriers. J Control Release 2007, 121(1-2):3-9.
    • (2007) J Control Release , vol.121 , Issue.1-2 , pp. 3-9
    • Champion, J.A.1    Katare, Y.K.2    Mitragotri, S.3
  • 110
    • 34547507000 scopus 로고    scopus 로고
    • Making polymeric micro- and nanoparticles of complex shapes
    • Champion J.A., Katare Y.K., Mitragotri S. Making polymeric micro- and nanoparticles of complex shapes. Proc Natl Acad Sci USA 2007, 104(29):11901-11904.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.29 , pp. 11901-11904
    • Champion, J.A.1    Katare, Y.K.2    Mitragotri, S.3
  • 111
    • 79551679772 scopus 로고    scopus 로고
    • Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles
    • Merkel T.J., Jones S.W., Herlihy K.P., Kersey F.R., Shields A.R., Napier M., et al. Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles. Proc Natl Acad Sci USA 2011, 108(2):586-591.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.2 , pp. 586-591
    • Merkel, T.J.1    Jones, S.W.2    Herlihy, K.P.3    Kersey, F.R.4    Shields, A.R.5    Napier, M.6
  • 113
    • 84876815363 scopus 로고    scopus 로고
    • Available from: URL:
    • US clinical trials 2012 Sept, Available from: URL:. http://www.clinicaltrials.gov.
    • (2012) US clinical trials
  • 114
    • 84876782374 scopus 로고    scopus 로고
    • Available from: URL:
    • Z-Medica QuikClot 2012 Sept, Available from: URL:. http://www.z-medica.com/healthcare/How-QuikClot-Works/How-QuikClot-Works.aspx.
    • (2012) Z-Medica QuikClot
  • 115
    • 0035194439 scopus 로고    scopus 로고
    • Recombinant Factor Vlla (NovoSeven) as a hemostatic agent
    • Hedner U. Recombinant Factor Vlla (NovoSeven) as a hemostatic agent. Semin Hematol 2001, 38(4 Suppl. 12):43-47.
    • (2001) Semin Hematol , vol.38 , Issue.4 SUPPL. 12 , pp. 43-47
    • Hedner, U.1
  • 116
    • 84876816458 scopus 로고    scopus 로고
    • Novo Nordisk Inc NovoSeven. Sept. Available from: URL:
    • Novo Nordisk Inc NovoSeven. 2012 Sept. Available from: URL: http://www.novosevenrt.com/.
    • (2012)
  • 117
    • 0036032289 scopus 로고    scopus 로고
    • Ongoing NovoSeven trials
    • Erhardtsen E. Ongoing NovoSeven trials. Intensive Care Med 2002, 28(Suppl. 2):S248-S255.
    • (2002) Intensive Care Med , vol.28 , Issue.SUPPL. 2
    • Erhardtsen, E.1
  • 118
    • 84876790087 scopus 로고    scopus 로고
    • Available from: URL:
    • CSL Behring LLC RioSTAP 2012 Sept, Available from: URL:. http://www.riastap.com/professional/default.aspx.
    • (2012) CSL Behring LLC RioSTAP
  • 119
    • 84876787157 scopus 로고    scopus 로고
    • Available from: URL:
    • CSL Behring LLC BioState 2012 Sept, Available from: URL:. http://www.csl.com.au/s1/cs/auhq/1199978997194/Web_Product_C/1196562715720/ProductDetail.htm.
    • (2012) CSL Behring LLC BioState
  • 120
    • 84876794836 scopus 로고    scopus 로고
    • Available from: URL:
    • Amgen NPlate 2012 Sept, Available from: URL:. http://www.nplate.com/patient/how-nplate-may-help/index.html%3fWT.srch%3d1.
    • (2012) Amgen NPlate
  • 122
    • 33646881754 scopus 로고    scopus 로고
    • Platelet transfusion therapy: from 1973 to 2005
    • Brand A., Novotny V., Tomson B. Platelet transfusion therapy: from 1973 to 2005. Hum Immunol 2006, 67:413-418.
    • (2006) Hum Immunol , vol.67 , pp. 413-418
    • Brand, A.1    Novotny, V.2    Tomson, B.3
  • 123
    • 84857756781 scopus 로고    scopus 로고
    • HLA alloimmunization against platelet transfusions: pathophysiology, significance, prevention and management
    • Pavenski K., Freedman J., Semple J. HLA alloimmunization against platelet transfusions: pathophysiology, significance, prevention and management. Tissue Antigens 2012, 78:237-245.
    • (2012) Tissue Antigens , vol.78 , pp. 237-245
    • Pavenski, K.1    Freedman, J.2    Semple, J.3
  • 124
    • 46949103859 scopus 로고    scopus 로고
    • Platelet transfusion refractoriness
    • Hod E., Schwartz J. Platelet transfusion refractoriness. Br J Haematol 2008, 142:348-360.
    • (2008) Br J Haematol , vol.142 , pp. 348-360
    • Hod, E.1    Schwartz, J.2
  • 125
    • 84859397936 scopus 로고    scopus 로고
    • Immunomodulatory mediators in platelet transfusion reactions
    • Morrell C. Immunomodulatory mediators in platelet transfusion reactions. Hematol Am Soc Hematol Educ Program 2011, 470-474.
    • (2011) Hematol Am Soc Hematol Educ Program , pp. 470-474
    • Morrell, C.1
  • 126
    • 15244343326 scopus 로고    scopus 로고
    • Transfusion-related actute lung injury
    • Sillliman C., Ambruso D., Boshkov L. Transfusion-related actute lung injury. Blood 2005, 105:2266-2273.
    • (2005) Blood , vol.105 , pp. 2266-2273
    • Sillliman, C.1    Ambruso, D.2    Boshkov, L.3
  • 127
    • 34547595111 scopus 로고    scopus 로고
    • Transfusion medicine
    • Stroncek D., Rebulla P. Transfusion medicine. Lancet 2007, 370:427-438.
    • (2007) Lancet , vol.370 , pp. 427-438
    • Stroncek, D.1    Rebulla, P.2
  • 129
    • 42349094203 scopus 로고    scopus 로고
    • Nanoparticles in medicine: therapeutic applications and developments
    • Zhang L., Gu F., Chan J., Wang A., Langer R., Farokhzad O. Nanoparticles in medicine: therapeutic applications and developments. Clin Pharmacol Ther 2008, 83(5):761-769.
    • (2008) Clin Pharmacol Ther , vol.83 , Issue.5 , pp. 761-769
    • Zhang, L.1    Gu, F.2    Chan, J.3    Wang, A.4    Langer, R.5    Farokhzad, O.6
  • 130
    • 77955607302 scopus 로고    scopus 로고
    • Factors that control the circulation time of nanoparticles in blood: challenges, solutions and future prospects
    • Yoo J.-W., Chambers E., Mitragotri S. Factors that control the circulation time of nanoparticles in blood: challenges, solutions and future prospects. Curr Pharm Des 2010, 16(21):2298-2307.
    • (2010) Curr Pharm Des , vol.16 , Issue.21 , pp. 2298-2307
    • Yoo, J.-W.1    Chambers, E.2    Mitragotri, S.3
  • 131
    • 84863666971 scopus 로고    scopus 로고
    • Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy
    • Yu M., Park J., Jon S. Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy. Theranostics 2012, 2(1):3-44.
    • (2012) Theranostics , vol.2 , Issue.1 , pp. 3-44
    • Yu, M.1    Park, J.2    Jon, S.3
  • 132
    • 52049117189 scopus 로고    scopus 로고
    • Evolution of phage display: from bioactive peptides to bioselective nanomaterials
    • Petrenko V. Evolution of phage display: from bioactive peptides to bioselective nanomaterials. Expert Opin Drug Deliv 2008, 5(8):1-12.
    • (2008) Expert Opin Drug Deliv , vol.5 , Issue.8 , pp. 1-12
    • Petrenko, V.1
  • 133
    • 78649776659 scopus 로고    scopus 로고
    • Release abilities of adenosine diphosphate from phospholipid vesicles with different membrane properties and their hemostatic effects as a platelet substitute
    • Okamura Y., Katsuno S., Suzuki H., Maruyama H., Handa M., Ikeda Y., et al. Release abilities of adenosine diphosphate from phospholipid vesicles with different membrane properties and their hemostatic effects as a platelet substitute. J Control Release 2010, 148(3):373-379.
    • (2010) J Control Release , vol.148 , Issue.3 , pp. 373-379
    • Okamura, Y.1    Katsuno, S.2    Suzuki, H.3    Maruyama, H.4    Handa, M.5    Ikeda, Y.6
  • 134
    • 84856552548 scopus 로고    scopus 로고
    • Biodegradable nanoparticles mimicking platelet binding as a targeted and controlled drug delivery system
    • Kona S., Dong J.-F., Liu Y., Tan J., Nguyen K.T. Biodegradable nanoparticles mimicking platelet binding as a targeted and controlled drug delivery system. Int J Pharm 2012, 423(2):516-524.
    • (2012) Int J Pharm , vol.423 , Issue.2 , pp. 516-524
    • Kona, S.1    Dong, J.-F.2    Liu, Y.3    Tan, J.4    Nguyen, K.T.5
  • 135
    • 84864832183 scopus 로고    scopus 로고
    • Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels
    • Korin N., Kanapathipillai M., Matthews B., Crescente M., Brill A., Mammoto T., et al. Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels. Science 2012, 337:738-742.
    • (2012) Science , vol.337 , pp. 738-742
    • Korin, N.1    Kanapathipillai, M.2    Matthews, B.3    Crescente, M.4    Brill, A.5    Mammoto, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.