Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels

Science

Volumn 337, Issue 6095, 2012, Pages 738-742

  Korin, Netanel ^a   Kanapathipillai, Mathumai ^a   Matthews, Benjamin D ^b   Crescente, Marilena ^b,c   Brill, Alexander ^b,c   Mammoto, Tadanori ^b   Ghosh, Kaustabh ^b   Jurek, Samuel ^b   Bencherif, Sidi A ^a,d   Bhatta, Deen ^d   Coskun, Ahmet U ^e   Feldman, Charles L ^c   Wagner, Denisa D ^b,c   Ingber, Donald E ^a,b,d  

^a HARVARD UNIVERSITY   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HARVARD UNIVERSITY   (United States)

^e Northeastern University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NANOPARTICLE; TISSUE PLASMINOGEN ACTIVATOR;

BIOPHYSICS; BLOOD; CARDIOVASCULAR DISEASE; DISEASE TREATMENT; DRUG; FLUID DYNAMICS; NANOTECHNOLOGY; RODENT; SHEAR STRESS; TECHNOLOGICAL DEVELOPMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOMIMETICS; CONTROLLED STUDY; DRUG EFFICACY; DRUG TARGETING; LUNG EMBOLISM; MESENTERIC ARTERY OCCLUSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SHEAR STRESS; THROMBOCYTE;

MUS;

EID: 84864832183     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1217815     Document Type: Article

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