Trehalose lyophilized platelets for wound healing

Wound Repair and Regeneration

Volumn 15, Issue 2, 2007, Pages 213-220

  Pietramaggiori, Giorgio ^a,b,c   Kaipainen, Arja ^d   Ho, David ^e,f   Orser, Cindy ^e   Pebley, Walter ^g   Rudolph, Alan ^e   Orgill, Dennis P ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF PADOVA   (Italy)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e Adlyfe Inc   (United States)

^f Cellphire Inc   (United States)

^g Oregon Freeze Dry Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TREHALOSE; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE MODEL; FREEZE DRYING; GRANULATION TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; THROMBOCYTE; VASCULARIZATION; WOUND HEALING;

ADMINISTRATION, TOPICAL; ANIMALS; BLOOD PLATELETS; CELL PROLIFERATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FREEZE DRYING; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED STRAINS; MODELS, ANIMAL; PLASMA; PLATELET TRANSFUSION; TREHALOSE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 33847723071     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/j.1524-475X.2007.00207.x     Document Type: Article

References (45)

1. Folkman J, Browder T, Palmblad J. Angiogenesis research: guidelines for translation to clinical application. Thromb Haemost 2001; 86: 23-33.
2. English D, Garcia JG, Brindley DN. Platelet-released phospholipids link haemostasis and angiogenesis. Cardiovasc Res 2001; 49: 588-99.
3. English D, Welch Z, Kovala AT, Harvey K, Volpert OV, Brindley DN, Garcia JG. Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis. FASEB J 2000; 14: 2255-65.
4. Hla T. Physiological and pathological actions of sphingosine 1-phosphate. Semin Cell Dev Biol 2004; 15: 513-20.
5. Whitman DH, Berry RL, Green DM. Platelet gel: an autologous alternative to fibrin glue with applications in oral and maxillofacial surgery. J Oral Maxillofac Surg 1997; 55: 1294-9.
6. Kim SG, Chung CH, Kim YK, Park JC, Lim SC. Use of particulate dentin-plaster of Paris combination with/without platelet-rich plasma in the treatment of bone defects around implants. Int J Oral Maxillofac Implants 2002; 17: 86-94.
7. Margolis DJ, Kantor J, Santanna J, Strom BL, Berlin JA. Effectiveness of platelet releasate for the treatment of diabetic neuropathic foot ulcers. Diabetes Care 2001; 24: 483-8.
8. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR. Platelet-rich plasma: growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998; 85: 638-46.
9. Bhanot S, Alex JC. Current applications of platelet gels in facial plastic surgery. Facial Plastic Surg 2002; 18: 27-33.
10. Frechette JP, Martineau I, Gagnon G. Platelet-rich plasmas: growth factor content and roles in wound healing. J Dent Res 2005; 84: 434-9.
11. Eppley BL, Woodell JE, Higgins J. Platelet quantification and growth factor analysis from platelet-rich plasma: implications for wound healing. Plastic Reconstr Surg 2004; 114: 1502-8.
12. Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, Ramirez C, Cavallari U, Trabetti E, Sabate M, Jimenez-Quevedo P, Hernandez R, Moreno R. Variability in platelet aggregation following sustained aspirin and clopidogrel treatment in patients with coronary heart disease and influence of the 807 c/t polymorphism of the glycoprotein ia gene. Am J Cardiol 2005; 96: 1095-9.
13. Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, Ramirez C, Sabate M, Jimenez-Quevedo P, Hernandez R, Moreno R, Escaned J, Alfonso F, et al. Platelet function profiles in patients with type 2 diabetes and coronary artery disease on combined aspirin and clopidogrel treatment. Diabetes 2005; 54: 2430-5.
14. Fritschi J, Christe M, Lammle B, Marbet GA, Berger W, Duckert F. Platelet aggregation, beta-thromboglobulin and platelet factor 4 in diabetes mellitus and in patients with vasculopathy. Thromb Haemost 1984; 52: 236-9.
15. Watala C, Boncler M, Gresner P. Blood platelet abnormalities and pharmacological modulation of platelet reactivity in patients with diabetes mellitus. Pharmacol Rep 2005; 57 (Suppl.): 42-58.
16. Muylle L, Joos M, Wouters E, De Bock R, Peetermans ME. Increased tumor necrosis factor alpha (TNF alpha), interleukin 1, and interleukin 6 (IL-6) levels in the plasma of stored platelet concentrates: relationship between TNF alpha and IL-6 levels and febrile transfusion reactions. Transfusion 1993; 33: 195-9.
17. Stack G, Snyder EL. Cytokine generation in stored platelet concentrates. Transfusion 1994; 34: 20-5.
18. Aye MT, Palmer DS, Giulivi A, Hashemi S. Effect of filtration of platelet concentrates on the accumulation of cytokines and platelet release factors during storage. Transfusion 1995; 35: 117-24.
19. Muylle L, Wouters E, De Bock R, Peetermans ME. Reactions to platelet transfusion: the effect of the storage time of the concentrate. Transfus Med 1992; 2: 289-93.
20. Sweeney JD, Holme S, Heaton WA, Nelson E. White cell-reduced platelet concentrates prepared by in-line filtration of platelet-rich plasma. Transfusion 1995; 35: 131-6.
21. Sweeney JD, Holme S, Stromberg RR, Heaton WA. In vitro and in vivo effects of prestorage filtration of apheresis platelets. Transfusion 1995; 35: 125-30.
22. Muylle L, Peetermans ME. Effect of prestorage leukocyte removal on the cytokine levels in stored platelet concentrates. Vox Sang 1994; 66: 14-7.
23. Flegel WA, Wiesneth M, Stampe D, Koerner K. Low cytokine contamination in buffy coat-derived platelet concentrates without filtration. Transfusion 1995; 35: 917-20.
24. Tablin F, Wolkers WF, Walker NJ, Oliver AE, Tsvetkova NM, Gousset K, Crowe LM, Crowe JH. Membrane reorganization during chilling: implications for long-term stabilization of platelets. Cryobiology 2001; 43: 114-23.
25. Devine P, Goldstein R, Linden JV, Postoway N, Hoffstadter LK, Hines DM. Data on apheresis, blood collection, and transfusion-related activities: statistical analyses of the American Association of Blood Banks institutional membership questionnaires. Transfusion 1996; 36: 375-81.
26. Crowe JH, Carpenter JF, Crowe LM. The role of vitrification in anhydrobiosis. Annu Rev Physiol 1998; 60: 73-103.
27. Wolkers WF, Walker NJ, Tablin F, Crowe JH. Human platelets loaded with trehalose survive freeze-drying. Cryobiology 2001; 42: 79-87.
28. Crowe JH, Tablin F, Wolkers WF, Gousset K, Tsvetkova NM, Ricker J. Stabilization of membranes in human platelets freeze-dried with trehalose. Chem Phys Lipids 2003; 122: 41-52.
29. Jaffe EA, Nachman RL, Becker CG, Minick CR. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 1973; 52: 2745-56.
30. Kubota Y, Kleinman HK, Martin GR, Lawley TJ. Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures. J Cell Biol 1988; 107: 1589-98.
31. Chua SC Jr., Chung WK, Wu-Peng XS, Zhang Y, Liu SM, Tartaglia L, Leibel RL. Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science 1996; 271: 994-6.
32. Kirchner LM, Meerbaum SO, Gruber BS, Knoll AK, Bulgrin J, Taylor RA, et al. Effects of vascular endothelial growth factor on wound closure rates in the genetically diabetic mouse model. Wound Repair Regen 2003; 11: 127-31.
33. Zimmermann R, Arnold D, Strasser E, Ringwald J, Schlegel A, Wiltfang J, Eckstein R. Sample preparation technique and white cell content influence the detectable levels of growth factors in platelet concentrates. Vox Sang 2003; 85: 283-9.
34. Chan RK, Liu PH, Pietramaggiori G, Ibrahim SI, Hechtman HB, Orgill DP. Effect of recombinant platelet-derived growth factor (Regranex(R)) on wound closure in genetically diabetic mice. J Burn Care Res 2006; 27: 202-5.
35. Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, Lakey ND, Culpepper J, Moore KJ, Breitbart RE, et al. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 1996; 84: 491-5.
36. www.idf.org/home/index.cfm.
37. Ktorza A, Bernard C, Parent V, Penicaud L, Froguel P, Lathrop M, Gauguier D. Are animal models of diabetes relevant to the study of the genetics of non-insulin-dependent diabetes in humans? Diabetes Metab 1997; 23 (Suppl. 2): 38-46.
38. Michaels Jt, Dobryansky M, Galiano RD, Bhatt KA, Ashinoff R, Ceradini DJ, Gurtner C. Topical vascular endothelial growth factor reverses delayed wound healing secondary to angiogenesis inhibitor administration. Wound Repair Regen 2005; 13: 506-12.
39. Pietramaggiori G, Kaipainen A, Czeczuga JM, Wagner CT, Orgill DP. Freeze-dried platelet-rich plasma shows beneficial healing properties in chronic wounds. Wound Repair Regen 2006; 14: 573-80.
40. Knighton DR, Fiegel VD. Growth factors and comprehensive surgical care of diabetic wounds. Curr Opin Gen Surg 1993: 32-9.
41. Galiano RD, Tepper OM, Pelo CR, Bhatt KA, Callaghan M, Bastidas N, Bunting S, Steinmetz HG, Gurtner GC. Topical vascular endothelial growth factor accelerates diabetic wound healing through increased angiogenesis and by mobilizing and recruiting bone marrow-derived cells. Am J Pathol 2004; 164: 1935-47.
42. Ferrara N. VEGF as a therapeutic target in cancer. Oncology 2005; 69 (Suppl. 3): 11-6.
43. Thurston G. Complementary actions of VEGF and angiopoietin-1 on blood vessel growth and leakage. J Anat 2002; 200: 575-80.
44. Phillips GD, Stone AM, Whitehead RA, Knighton DR. Platelet derived wound healing factors (PDWHF) accelerate and augment wound healing angiogenesis in the rat. In Vivo 1994; 8: 167-71.
45. Chan RK, Liu P, Lew DH, Ibrahim SI, Srey R, Valeri CR, Hechtman HB, Orgill DP. Expired liquid preserved platelet releasates retain proliferative activity. J Surg Res 2005; 126: 55-8.